المؤلفون: Nursasi Handayani, Abdul Gofur

المصدر: Jurnal Kedokteran Hewan, Vol 11, Iss 4 (2018)

مصطلحات موضوعية: epimetrium thickness, mice, myometrium thickness, pulutan, uterine diameter, Animal culture, SF1-1100, Veterinary medicine, SF600-1100

الوصف: The purpose of this research was to determine the effect of decoction of pulutan leaves simplicia(Urenalobata L.) on the development of the uterus of Balb C mice (Musmusculus). Female mice aged 10-12 weeks were given decoction of pulutan leaves simplicia with concentration of 5%, 7.5%, 10%, 12.5%, 15%, and control. The administration of pulutan leaves was performed by gavage for 11 consecutive days. On day 12, mice were dissected, then, the uterus was taken for histological preparations using paraffin method. Data such as uterine diameter and myometrium and epimetrium thickness were analyzed using one way analysis of variance followed by least significant different. The results showed that decoction of pulutan leaves simplicia decrease the uterine diameter and epimetrium and myometrium thickness compared to control. The decrease of uterine diameter and uterine myometrium and epimetrium thickness was started at the concentration of 7.5%. Decoction of pulutan leaves simplicia could reduce uterine diameter and thickness of uterine myometrium and epimetrium, thus, it might decrease the uterine function as the site of implantation. The decline in the function of the uterus might decrease the number of born children, thus decoction of pulutan leaves simplicia is potential as antifertility agent.

وصف الملف: electronic resource

Relation: https://jurnal.usk.ac.id/JKH/article/view/6261; https://doaj.org/toc/1978-225X; https://doaj.org/toc/2502-5600

URL الوصول: https://doaj.org/article/226139f966d74ada8ca7ea52f0ccda1e

المؤلفون: Cicilia Novi Primiani, Umie Lestari, Mohammad Amin, Sutiman Bambang Sumitro

المصدر: Journal of Biological Researches, Vol 18, Iss 2, Pp 1-7 (2014)

مصطلحات موضوعية: compounds dynamic, daidzein, myometrium, Pachyrhizus erosus, Science, Biology (General), QH301-705.5

الوصف: Daidzein compounds dynamic and the effect of yam tuber (Pachyrhizus erosus (L)) Urb on myometrium rats model of estrogenic were investigated. Twentyfour of 5 months-old female Sprague Dawley rats were randomly assigned to three groups as followed, control, Daidzein administraton and yam tuber juice administration for 24 days. The administration of yam tuber juice were given by orally using a stomach with gavage tube in the morning. Every 8 h, the rats blood and urine were collected from tail until 24 h. The treatment were continued until 24 days. The result showed that the level of daidzein in blood and urine of rats that administratered by Yam tuber juice is lower than pure daidzein treatment rats every 8 until 24 hours of collection. The results demonstrated that the administration of yam tuber juice significantly myometrium proliferated in rats. It is assumed that genistein and quercetin is estrogenic as found in daidzein so that the miometrium is potentially more effecctive. This study suggest that phytoestrogen compound from Pachyrhizus erosus may offer a potential as natural estrogenic in women.

وصف الملف: electronic resource

Relation: http://berkalahayati.org/journal/f1171a78; https://doaj.org/toc/0852-6834; https://doaj.org/toc/2337-389X

URL الوصول: https://doaj.org/article/a63949901a8f4b96abdd4d1719787cc9