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المؤلفون: Ana Carvalho, Eric J. Lambie, Hai Wei, Daniel S. Osorio, Barbara Conradt
المساهمون: Instituto de Investigação e Inovação em Saúde
المصدر: PLoS Genetics, Vol 16, Iss 9, p e1008912 (2020)
PLoS Geneticsمصطلحات موضوعية: Cancer Research, DNA-Binding Proteins / genetics, Cell, Apoptosis, Neural Stem Cells / metabolism, Snail, Cell Polarity / physiology, QH426-470, medicine.disease_cause, Myosin Type II / metabolism, Animals, Genetically Modified, 0302 clinical medicine, Neural Stem Cells, Cytoskeletal Proteins / metabolism, Phosphorylation, Genetics (clinical), Caenorhabditis elegans, Neurons, 0303 health sciences, Cell Death, biology, Kinase, Chemistry, Neurons / metabolism, Cell Polarity, Actomyosin, Protein Serine-Threonine Kinases / genetics, Actomyosin / metabolism, Cell biology, DNA-Binding Proteins, medicine.anatomical_structure, Protein Serine-Threonine Kinases / metabolism, Snail Family Transcription Factors / genetics, Snail Family Transcription Factors / metabolism, Context (language use), Protein Serine-Threonine Kinases, Neuroblast division, 03 medical and health sciences, Neuroblast, Transcription Factors / genetics, biology.animal, Caenorhabditis elegans Proteins / metabolism, Genetics, medicine, Animals, Cell Death / physiology, Caenorhabditis elegans Proteins, Molecular Biology, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Myosin Type II, Transcription Factors / metabolism, fungi, DNA-Binding Proteins / metabolism, biology.organism_classification, Cytoskeletal Proteins, Caenorhabditis elegans Proteins / genetics, Snail Family Transcription Factors, Apoptosis / physiology, Carcinogenesis, 030217 neurology & neurosurgery, Transcription Factors
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e89eb8b227c8d8bb6fd9f36c74a4f95
https://doi.org/10.1101/2020.06.04.133983 -
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المؤلفون: Victor A. Neel, Seung-Hee Jo, G. Paolo Dotto, Maria-Giuseppina Procopio, Sandro Goruppi, Andrea Clocchiatti
المصدر: Cell Reports, Vol 20, Iss 10, Pp 2468-2479 (2017)
Cell reports, vol. 20, no. 10, pp. 2468-2479مصطلحات موضوعية: squamous cell carcinoma, 0301 basic medicine, autophagy, Stromal cell, cancer-associated fibroblast, Notch signaling pathway, Fluorescent Antibody Technique, Protein Serine-Threonine Kinases, Biology, Zinc Finger Protein GLI1, Article, General Biochemistry, Genetics and Molecular Biology, Mice, ULK3, 03 medical and health sciences, Cancer-Associated Fibroblasts, Downregulation and upregulation, GLI2, Animals, Humans, tumor microenvironment, Gene silencing, CAF, Autophagy/physiology, Cancer-Associated Fibroblasts/metabolism, Female, Fibroblasts/metabolism, Immunoglobulin J Recombination Signal Sequence-Binding Protein/metabolism, Protein-Serine-Threonine Kinases/genetics, Protein-Serine-Threonine Kinases/metabolism, Signal Transduction/genetics, Signal Transduction/physiology, Zinc Finger Protein GLI1/genetics, Zinc Finger Protein GLI1/metabolism, CSL/RBPJ, GLI, SCC, cancer stroma, lcsh:QH301-705.5, RBPJ, Autophagy, Fibroblasts, 030104 developmental biology, lcsh:Biology (General), Immunoglobulin J Recombination Signal Sequence-Binding Protein, Cancer research, Signal transduction, Signal Transduction
وصف الملف: application/pdf
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المؤلفون: Jawahar Kopparam, Mauro Delorenzi, Etienne Meylan, Paolo Angelino, Nadine Zangger, Alessandra Piersigilli, Johanna Chiffelle
المصدر: Cell death and differentiation, vol. 24, no. 10, pp. 1761-1771
Cell Death and Differentiationمصطلحات موضوعية: STAT3 Transcription Factor, 0301 basic medicine, Original Paper, Gene knockdown, biology, Adenocarcinoma/metabolism, Cell Differentiation/physiology, Genes, ras/genetics, Humans, Lung Neoplasms/metabolism, Phosphorylation, Protein-Serine-Threonine Kinases/metabolism, Signal Transduction/physiology, Cancer, Lysyl oxidase, Cell Biology, medicine.disease, Proto-Oncogene Proteins p21(ras), Extracellular matrix, 03 medical and health sciences, 030104 developmental biology, HMGA2, Neoplasms, Extracellular, medicine, biology.protein, Cancer research, Adenocarcinoma, Lung cancer, Molecular Biology
وصف الملف: application/pdf
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المؤلفون: Yin Xu, Ivan Stamenkovic, Qin Yu
المصدر: Cancer Research, vol. 70, no. 6, pp. 2455-2464
مصطلحات موضوعية: Cancer Research, Recombinant Fusion Proteins, medicine.medical_treatment, Apoptosis, Cell Growth Processes, Protein Serine-Threonine Kinases, Article, Targeted therapy, Mice, Downregulation and upregulation, Cancer stem cell, Glioma, Chlorocebus aethiops, medicine, Animals, Humans, RNA, Small Interfering, Hippo signaling pathway, biology, Brain Neoplasms, CD44, Antigens, CD44/biosynthesis, Antigens, CD44/genetics, Apoptosis/physiology, Brain Neoplasms/drug therapy, Brain Neoplasms/genetics, COS Cells, Cell Growth Processes/physiology, Cercopithecus aethiops, Glioblastoma/drug therapy, Glioblastoma/genetics, Immunoglobulin Fc Fragments/genetics, Immunoglobulin Fc Fragments/pharmacology, Protein-Serine-Threonine Kinases/metabolism, Proto-Oncogene Proteins c-met/metabolism, RNA, Small Interfering/genetics, Recombinant Fusion Proteins/genetics, Recombinant Fusion Proteins/isolation & purification, Signal Transduction, Up-Regulation, Proto-Oncogene Proteins c-met, medicine.disease, nervous system diseases, Immunoglobulin Fc Fragments, Hyaluronan Receptors, Oncology, Cancer cell, biology.protein, Cancer research, Signal transduction, Glioblastoma
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50a24c9cee259d8d91ac4f279cecd33b
https://doi.org/10.1158/0008-5472.can-09-2505 -
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المؤلفون: Dominique Muller, Emmanuel Thévenot, Véronique Rousseau, Bernadette Boda, Jean-Vianney Barnier, Patricia Kreis
المصدر: Journal of Biological Chemistry, Vol. 282, No 29 (2007) pp. 21497-21506
مصطلحات موضوعية: rac1 GTP-Binding Protein, Dendritic spine, Hippocampus/metabolism, Synapses/metabolism, Neurons/metabolism, Dendritic spine morphogenesis, Protein Serine-Threonine Kinases, Biology, Hippocampus, Models, Biological, Synaptic Transmission, Biochemistry, Protein-Serine-Threonine Kinases/metabolism/ physiology, Cdc42 GTP-Binding Protein/ metabolism, Cercopithecus aethiops, Rac1 GTP-Binding Protein/metabolism, Mental Retardation/genetics/ metabolism, Intellectual Disability, Chlorocebus aethiops, Animals, Small GTPase, Kinase activity, cdc42 GTP-Binding Protein, p21-activated kinases, Molecular Biology, Neurons, Effector, Cell Biology, ddc:616.8, Rats, Cell biology, P21-Activated Kinases, p21-Activated Kinases, Cdc42 GTP-Binding Protein, COS Cells, Mutation, Synapses, Synaptic plasticity, Cancer research
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3661c681716036ec9b8a068da4795c40
https://doi.org/10.1074/jbc.m703298200 -
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المؤلفون: Maria Stefaniotou, Carol Murphy, Theodore Fotsis, Konstantinos Psillas, Marina Ziche, Lucia Morbidelli, Eleni Bagli
المصدر: Cancer Research. 64:7936-7946
مصطلحات موضوعية: Vascular Endothelial Growth Factor A, Cancer Research, p38 Mitogen-Activated Protein Kinases/metabolism, Angiogenesis, Angiogenesis Inhibitors, p38 Mitogen-Activated Protein Kinases, Angiogenesis Inhibitors/*pharmacology, Mice, chemistry.chemical_compound, Luteolin/*pharmacology, Phosphorylation, Luteolin, Cells, Cultured, Phosphoinositide-3 Kinase Inhibitors, Mice, Inbred BALB C, Kinase, Protein-Serine-Threonine Kinases/metabolism, Vascular endothelial growth factor, Oncology, Biochemistry, Female, Rabbits, Mitogen-Activated Protein Kinases, Mitogen-Activated Protein Kinases/metabolism, Cell Division, Cell Survival/drug effects, Ribosomal Protein S6 Kinases/metabolism, Cell Survival, Cell Division/drug effects, P70-S6 Kinase 1, Protein Serine-Threonine Kinases, Biology, Vascular Endothelial Growth Factor A/*antagonists & inhibitors, Proto-Oncogene Proteins, Animals, Humans, Kinase activity, Protein kinase B, PI3K/AKT/mTOR pathway, Ribosomal Protein S6 Kinases, Endothelial Cells, Neoplasms, Experimental, Proto-Oncogene Proteins/metabolism, Phosphatidylinositol 3-Kinases/*antagonists & inhibitors, Endothelial Cells/cytology/*drug effects, chemistry, Neoplasms, Experimental/blood supply/drug therapy, Cancer research, Proto-Oncogene Proteins c-akt
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051f8eebd4e63ff6b21dd5e3e5012aec
https://doi.org/10.1158/0008-5472.can-03-3104 -
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المؤلفون: Jean Christophe Noël, Xavier Catteau, Philippe Simon
المصدر: BMC cancer, 14 (1
BMC Cancerمصطلحات موضوعية: Cancer Research, Pathology, Receptor, Transforming Growth Factor-beta Type I, Transforming Growth Factor beta1 -- metabolism, CD34, Antigens, CD34, Actins -- metabolism, Metastasis, Tumor Microenvironment, SMA, Myofibroblasts, skin and connective tissue diseases, Lymph node, Aged, 80 and over, Carcinoma, Ductal, Breast, Fibrocytes, Middle Aged, medicine.anatomical_structure, Oncology, Lymphatic Metastasis, Female, Protein-Serine-Threonine Kinases -- metabolism, Breast carcinoma, Biologie, Research Article, Signal Transduction, Adult, medicine.medical_specialty, Stromal cell, Antigens, CD34 -- metabolism, Breast Neoplasms, Protein Serine-Threonine Kinases, Stromal Cells -- metabolism -- pathology, Transforming Growth Factor beta1, Breast cancer, Carcinoma, Ductal, Breast -- metabolism -- pathology, Receptors, Transforming Growth Factor beta -- metabolism, Genetics, medicine, Humans, Lymphatic Metastasis -- pathology, Aged, Myofibroblasts -- cytology -- metabolism -- pathology, Tumor microenvironment, business.industry, medicine.disease, Actins, Cancérologie, TGF-ß, Stromal Cells, business, Receptors, Transforming Growth Factor beta, Breast Neoplasms -- metabolism -- pathology
وصف الملف: 1 full-text file(s): application/pdf
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المؤلفون: Alexander Hoischen, Nathalie Janel, Anne Badel, Björn Menten, Clémentine Ripoll, Jean-Maurice Delabar, Stylianos E. Antonarakis, Bregje W.M. van Bon, Joseph Gecz, Henri Bléhaut, Asma Tlili, Nele Bockaert, Eva Benabou, R. Touraine, Samantha Stora, Yann Grattau, Bert B.A. de Vries, Anne Ronan, Marie-Claude Potier, Dominique Campion
المصدر: Molecular Neurobiology, 46, 2, pp. 297-303
Molecular Neurobiology, Vol. 46, No 2 (2012) pp. 297-303
Molecular Neurobiology, 46, 297-303مصطلحات موضوعية: Down syndrome, Candidate gene, Brain-Derived Neurotrophic Factor/blood/metabolism, DYRK1A, Chromosomes, Human, Pair 21, Neuroscience (miscellaneous), Aneuploidy, Protein Serine-Threonine Kinases, Biology, Cell Line, Mice, Cellular and Molecular Neuroscience, medicine, Animals, Humans, ddc:576.5, Lymphocytes, Allele, Chromosome Aberrations, Brain-Derived Neurotrophic Factor, Genetic disorder, Chromosomes, Human, Pair 21/genetics, Protein-Serine-Threonine Kinases/metabolism, Middle Aged, Protein-Tyrosine Kinases, medicine.disease, Protein-Tyrosine Kinases/metabolism, Neurology, Down Syndrome/blood/enzymology, Cancer research, Down Syndrome, Lymphocytes/enzymology, Chromosome 21, Trisomy, Genetics and epigenetic pathways of disease Genomic disorders and inherited multi-system disorders [NCMLS 6]
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المصدر: PLoS ONE
PLoS ONE, Vol 5, Iss 6, p e11084 (2010)
Plos One, vol. 5, no. 6, pp. e11084مصطلحات موضوعية: Angiogenesis, Science, Receptor, Transforming Growth Factor-beta Type I, Biology, Protein Serine-Threonine Kinases, Metastasis, Neovascularization, 03 medical and health sciences, Mice, 0302 clinical medicine, In vivo, Cell Movement, Radiation, Ionizing, medicine, Animals, Cardiovascular Disorders/Vascular Biology, 030304 developmental biology, 0303 health sciences, Multidisciplinary, Neovascularization, Pathologic, Cancer, Cell Movement/radiation effects, Endothelium, Vascular/cytology, Endothelium, Vascular/metabolism, Mice, Inbred C57BL, Neovascularization, Pathologic/radiotherapy, Protein-Serine-Threonine Kinases/metabolism, Receptors, Transforming Growth Factor beta/metabolism, medicine.disease, 3. Good health, Cell biology, Endothelial stem cell, Cell Biology/Cell Adhesion, Oncology, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, Medicine, Endothelium, Vascular, medicine.symptom, Receptors, Transforming Growth Factor beta, Ex vivo, Research Article
وصف الملف: application/pdf
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المؤلفون: Gian-Carlo Alghisi, E. Roberts, Susan M. Gasser, Yegor S. Vassetzky
المصدر: Scopus-Elsevier
British Journal of Cancer, vol. 73, no. 10, pp. 1201-1209
British Journal of Cancerمصطلحات موضوعية: Cancer Research, Mutant, Molecular Sequence Data, Drug Resistance, Gene Expression, Saccharomyces cerevisiae, Protein Serine-Threonine Kinases, medicine.disease_cause, Structure-Activity Relationship, Plasmid, medicine, Amino Acid Sequence, Casein Kinase II, Etoposide, Sequence Deletion, Mutation, Binding Sites, biology, Topoisomerase, Point mutation, Genetic Complementation Test, Phosphoproteins, Molecular biology, Culture Media, DNA Topoisomerases, Type II, Oncology, biology.protein, Ectopic expression, Casein kinase 2, medicine.drug, Research Article, DNA Topoisomerases, Type II/metabolism, Etoposide/pharmacology, Phosphoproteins/metabolism, Protein-Serine-Threonine Kinases/metabolism, Saccharomyces cerevisiae/enzymology
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d45543bdc04a6da5ff17cb9eba2be5d7
http://www.scopus.com/inward/record.url?eid=2-s2.0-0029896892&partnerID=MN8TOARS
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