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المؤلفون: Vikrant Kumar, Bryn Hardwick, Saranya Giridharan, Sneha Sudhakar, Markus Muellner, Manjunath A. Hurakadli, Ashok R. Venkitaraman, Gayathri Sadasivam, T.K. Prasad, Neelagandan Kamariah, Grahame J. McKenzie, Alex T. Crooks, Subashini Mathivanan, Paul M. Watt, Miguel Coelho, Sneha Bairy, Nadia Milech, Chandan Mithra, Christopher J. Torrance, Amy Emery, Kavitha Bharatham
المصدر: Cell Chemical Biology
مصطلحات موضوعية: Phenotypic screening, Systems biology, Clinical Biochemistry, Peptide, Computational biology, Biology, medicine.disease_cause, 01 natural sciences, Biochemistry, Article, Protein–protein interaction, law.invention, Small Molecule Libraries, protein-protein interaction, Peptide Library, target identification, law, Drug Discovery, medicine, Humans, Genes, Tumor Suppressor, Phosphorylation, FOXO3a, lead discovery, Peptide library, Molecular Biology, Cells, Cultured, 14-3-3, Pharmacology, chemistry.chemical_classification, Mutation, 010405 organic chemistry, Forkhead Box Protein O3, phenotypic screening, Small molecule, 0104 chemical sciences, prokaryal genomes, target validation, chemistry, bioactive peptide, Molecular Medicine, Suppressor, Female, protein interference
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82261f81e78bea18e12f385b6c100941
https://doi.org/10.1016/j.chembiol.2021.05.009 -
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المؤلفون: Paul M. Watt, Nadia Milech, Shane R. Stone
المصدر: Current Opinion in Chemical Biology. 38:127-133
مصطلحات موضوعية: 0301 basic medicine, Intracellular protein, Phenotypic screening, Drug Evaluation, Preclinical, Intracellular Space, Computational biology, Biology, Biochemistry, Molecular biology, Phenotype, Peptide Fragments, Analytical Chemistry, Protein–protein interaction, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Peptide Library, Animals, Humans, Molecular Targeted Therapy, Peptide library, 030217 neurology & neurosurgery, Binding affinities
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المؤلفون: Paula T. Cunningham, Mark Anastasas, Tatjana Heinrich, Laura Florez, Danie Champain, Theresa Connor, Paul M. Watt, Nadia Milech, Scott Winslow, Abbie M. Adams, Karen M. Kroeger, Richard W. Francis, Brooke A. C. Longville, Robert E. Dewhurst, Shane R. Stone, Yew Foon Tan, M. Scobie, Clinton M. Hall, Helena M. Viola, Maria Kerfoot, Livia C. Hool, Heique M. Bogdawa, Arne Skerra, Katrin Hoffmann, Ferrer Ong, Volker Morath, Suzy M. Juraja, Sue Fletcher, Gregory A. Weiss, Richard Hopkins
المصدر: Scientific reports, vol 8, iss 1
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)مصطلحات موضوعية: 0301 basic medicine, Male, Cell, Druggability, Drug Evaluation, Preclinical, lcsh:Medicine, Cell-Penetrating Peptides, Inbred C57BL, Mice, 0302 clinical medicine, Drug Delivery Systems, Bacteriophage T7, Carbon-Nitrogen Ligases, Muscular Dystrophy, lcsh:Science, Microscopy, Multidisciplinary, Chemistry, Escherichia coli Proteins, Circular Dichroism, Preclinical, Other Physical Sciences, medicine.anatomical_structure, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Biotinylation, Development of treatments and therapeutic interventions, Intracellular, Endosome, Computational biology, CHO Cells, Article, Fluorescence, 03 medical and health sciences, Cricetulus, Rare Diseases, Peptide Library, medicine, Animals, Humans, Peptide library, Animal, HEK 293 cells, lcsh:R, Duchenne, Mice, Inbred C57BL, Muscular Dystrophy, Duchenne, Repressor Proteins, Disease Models, Animal, 030104 developmental biology, HEK293 Cells, Orphan Drug, Microscopy, Fluorescence, Cytoplasm, Disease Models, Drug Evaluation, lcsh:Q, Biochemistry and Cell Biology, Generic health relevance
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2982281cc58305b13bc410a28e61452e
https://escholarship.org/uc/item/9539k69b -
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المؤلفون: Tatjana Heinrich, Renae K. Barr, Richard W. Francis, Heique M. Bogdawa, Nadia Milech, Shane R. Stone, Robert E. Dewhurst, Paul M. Watt
مصطلحات موضوعية: chemistry.chemical_classification, Empirical data, Amino acid composition, chemistry, Peptide, Identification (biology), Computational biology, Biology, Combinatorial chemistry, Genome, Phenotype
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9f7cd2b256feed269730aa0148f5dbec
https://doi.org/10.1039/9781788011532-00497 -
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المؤلفون: Amanda J. Meade, Bruno P. Meloni, Paul M. Watt, Nadia Milech, Neville W. Knuckey, William R Gow, Kym Campbell
المصدر: Journal of Cerebral Blood Flow & Metabolism. 31:e1-e8
مصطلحات موضوعية: Male, medicine.medical_treatment, Oncogene Protein p65(gag-jun), Excitotoxicity, Ischemia, Neuropeptide, Blood Pressure, Pharmacology, medicine.disease_cause, Neuroprotection, Negative Result, Rats, Inbred SHR, Laser-Doppler Flowmetry, medicine, Animals, Mitogen-Activated Protein Kinase 8, Saline, Stroke, Dose-Response Relationship, Drug, business.industry, Neuropeptides, c-jun, JNK Mitogen-Activated Protein Kinases, Glutamate receptor, Infarction, Middle Cerebral Artery, Carbon Dioxide, medicine.disease, Rats, Oxygen, Neuroprotective Agents, Neurology, Ischemic Attack, Transient, Anesthesia, Neurology (clinical), Peptides, Cardiology and Cardiovascular Medicine, business, Psychomotor Performance
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المؤلفون: Paul M. Watt, Tanya Armstrong, A. Estcourt, C.K. Woh, Simon Reid, R. Jefferies, Anthony Armson, Rongchang Yang, Nadia Milech, T. Weldt, Richard Hopkins, Una Ryan
المصدر: Experimental parasitology. 148
مصطلحات موضوعية: 030231 tropical medicine, Immunology, Molecular Sequence Data, Cryptosporidium, Microbiology, 03 medical and health sciences, 0302 clinical medicine, IMP Dehydrogenase, IMP dehydrogenase, Peptide Library, Cell Line, Tumor, Two-Hybrid System Techniques, parasitic diseases, medicine, Animals, Humans, Amino Acid Sequence, Inosine-5′-monophosphate dehydrogenase, Inosine, Nucleotide salvage, 030304 developmental biology, 0303 health sciences, biology, Base Sequence, Dose-Response Relationship, Drug, Oocysts, Nitazoxanide, General Medicine, DNA, Protozoan, biology.organism_classification, 3. Good health, Infectious Diseases, Cryptosporidium parvum, Biochemistry, biology.protein, Parasitology, Cattle, Peptides, Cryptosporidium hominis, Genome, Bacterial, medicine.drug, Plasmids
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المؤلفون: Paul M. Watt, Ursula R. Kees, Nadia Milech
المصدر: Genes, Chromosomes and Cancer. 32:275-280
مصطلحات موضوعية: Homeodomain Proteins, Genetics, Gene isoform, Cancer Research, Molecular Sequence Data, fungi, Chromosomal translocation, Biology, medicine.disease, Homology (biology), Leukemia, Cell culture, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Proto-Oncogene Proteins, medicine, Transcriptional regulation, Humans, Protein Isoforms, Homeobox, splice, Transcription Factors
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المؤلفون: Bruce W. S. Robinson, Julia V. Marley, Michael J. Garlepp, Suzanne Loh, C.C. Leong, Nadia Milech
المصدر: International Journal of Cancer. 71:476-482
مصطلحات موضوعية: Cancer Research, fungi, Genetic transfer, Transfection, Biology, Immune system, Oncology, Antigen, Cell culture, Immunity, Immunology, Cancer research, Cytotoxic T cell, CD8
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c7cea8eaf2fb3b442c3cb8e11697e331
https://doi.org/10.1002/(sici)1097-0215(19970502)71:3<476::aid-ijc28>3.0.co;2-c -
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المؤلفون: Neville W. Knuckey, Richard Hopkins, Paul M. Watt, Bruno P. Meloni, Nadia Milech, Amanda J. Craig
المصدر: Cellular and molecular neurobiology. 34(2)
مصطلحات موضوعية: Kainic acid, Cell Survival, Cysteamine, Molecular Sequence Data, Neurotoxins, Excitotoxicity, Glutamic Acid, Peptide, Cell-Penetrating Peptides, Pharmacology, medicine.disease_cause, Neuroprotection, Models, Biological, Rats, Sprague-Dawley, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Inhibitory Concentration 50, Ischemia, Medicine, Animals, Amino Acid Sequence, Peptide sequence, Cells, Cultured, chemistry.chemical_classification, Cerebral Cortex, Neurons, Kainic Acid, business.industry, Cell Biology, General Medicine, Glutamic acid, In vitro, Amino acid, Rats, Neuroprotective Agents, chemistry, Gene Products, tat, business, Carrier Proteins, Peptides, Oligopeptides
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المصدر: The international journal of biochemistrycell biology. 45(8)
مصطلحات موضوعية: Doublecortin Protein, Proto-Oncogene Proteins c-jun, p38 mitogen-activated protein kinases, Molecular Sequence Data, Peptide, Biology, Biochemistry, Binding, Competitive, p38 Mitogen-Activated Protein Kinases, Substrate Specificity, Mice, medicine, Animals, Amino Acid Sequence, Surface plasmon resonance, Phosphorylation, Protein Kinase Inhibitors, Enzyme Assays, ets-Domain Protein Elk-1, chemistry.chemical_classification, Binding Sites, Activating Transcription Factor 2, Kinase, JNK Mitogen-Activated Protein Kinases, Cell Biology, Retro-Inverso Peptide, ErbB Receptors, Immobilized Proteins, Mechanism of action, chemistry, Docking (molecular), medicine.symptom, Peptides, Protein Binding