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المؤلفون: Richard Cunningham, Siyang Jia, Krishna Purohit, Omar Salem, Ning Sze Hui, Yue Lin, Neil O. Carragher, Carsten Gram Hansen
المصدر: Cunningham, R, Jia, S, Purohit, K, Salem, O, Sze Hui, N, Lin, Y, Carragher, N O & Hansen, C G 2023, ' YAP/TAZ activation predicts clinical outcomes in mesothelioma and is conserved in in vitro model of driver mutations ', Clinical and Translational Medicine, vol. 13, no. 2, pp. e1190 . https://doi.org/10.1002/ctm2.1190
مصطلحات موضوعية: Mutation/genetics, Transcriptional Coactivator with PDZ-Binding Motif Proteins, Transcription Factors/genetics, Humans, Molecular Medicine, Medicine (miscellaneous), Hippo Signaling Pathway, Protein Serine-Threonine Kinases/metabolism, YAP-Signaling Proteins, Mesothelioma/genetics
وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document; application/pdf
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المؤلفون: António Rego, Manuela Côrte-Real, Filipa Mendes, Vítor Costa, Susana R. Chaves
المساهمون: Instituto de Investigação e Inovação em Saúde
المصدر: Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Oxidative Medicine and Cellular Longevityمصطلحات موضوعية: Aging, Ceramide, Saccharomyces cerevisiae Proteins, Article Subject, Saccharomyces cerevisiae, Protein Serine-Threonine Kinases, Cell fate determination, Mitochondrion, Biochemistry, chemistry.chemical_compound, Saccharomyces cerevisiae / metabolism, Acetic Acid, Saccharomyces cerevisiae Proteins / metabolism, QH573-671, Cell Death, biology, Chemistry, Endoplasmic reticulum, Cytochrome c, Mitochondria / metabolism, Cell Biology, General Medicine, Sphingolipid, Mitochondria, Acetic Acid / metabolism, Cell biology, Apoptosis, Protein Serine-Threonine Kinases / metabolism, biology.protein, Phosphorylation, Cytology, Research Article
وصف الملف: application/pdf; text/xhtml
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المساهمون: Psychiatrie & Neuropsychologie, RS: MHeNs - R3 - Neuroscience
المصدر: Methods in Molecular Biology ISBN: 9781071608135
Lipid Rafts: Methods and Protocols, 2187, 327-335مصطلحات موضوعية: 0301 basic medicine, Sphingolipids/metabolism, Cholera Toxin/metabolism, Fluorescent Antibody Technique/methods, Carrier Proteins/metabolism, Membrane Microdomains/metabolism, Immunofluorescence, medicine.disease_cause, Cell Line, 03 medical and health sciences, 0302 clinical medicine, Organelle, medicine, Fluorescence microscope, Humans, Protein Serine-Threonine Kinases/metabolism, Lipid localization, Lipid bilayer, Lipid raft, medicine.diagnostic_test, Chemistry, Cell Membrane/metabolism, Cholera toxin, Sphingolipid, HEK293 Cells, 030104 developmental biology, Fluorescent Dyes/metabolism, Membrane Lipids/metabolism, Biophysics, Membrane Proteins/metabolism, lipids (amino acids, peptides, and proteins), 030217 neurology & neurosurgery, Antibodies/metabolism
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c72686d69e90f8496e6010e983b1c29
https://doi.org/10.1007/978-1-0716-0814-2_19 -
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المؤلفون: Ana Carvalho, Eric J. Lambie, Hai Wei, Daniel S. Osorio, Barbara Conradt
المساهمون: Instituto de Investigação e Inovação em Saúde
المصدر: PLoS Genetics, Vol 16, Iss 9, p e1008912 (2020)
PLoS Geneticsمصطلحات موضوعية: Cancer Research, DNA-Binding Proteins / genetics, Cell, Apoptosis, Neural Stem Cells / metabolism, Snail, Cell Polarity / physiology, QH426-470, medicine.disease_cause, Myosin Type II / metabolism, Animals, Genetically Modified, 0302 clinical medicine, Neural Stem Cells, Cytoskeletal Proteins / metabolism, Phosphorylation, Genetics (clinical), Caenorhabditis elegans, Neurons, 0303 health sciences, Cell Death, biology, Kinase, Chemistry, Neurons / metabolism, Cell Polarity, Actomyosin, Protein Serine-Threonine Kinases / genetics, Actomyosin / metabolism, Cell biology, DNA-Binding Proteins, medicine.anatomical_structure, Protein Serine-Threonine Kinases / metabolism, Snail Family Transcription Factors / genetics, Snail Family Transcription Factors / metabolism, Context (language use), Protein Serine-Threonine Kinases, Neuroblast division, 03 medical and health sciences, Neuroblast, Transcription Factors / genetics, biology.animal, Caenorhabditis elegans Proteins / metabolism, Genetics, medicine, Animals, Cell Death / physiology, Caenorhabditis elegans Proteins, Molecular Biology, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Myosin Type II, Transcription Factors / metabolism, fungi, DNA-Binding Proteins / metabolism, biology.organism_classification, Cytoskeletal Proteins, Caenorhabditis elegans Proteins / genetics, Snail Family Transcription Factors, Apoptosis / physiology, Carcinogenesis, 030217 neurology & neurosurgery, Transcription Factors
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e89eb8b227c8d8bb6fd9f36c74a4f95
https://doi.org/10.1101/2020.06.04.133983 -
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المؤلفون: Alain Doucet, Marc Maillard, Caroline Ronzaud, Lydie Cheval, Alessia Spirli, David Penton, Olivier Staub, Anne Debonneville, Johannes Loffing
المساهمون: Centre de Recherche des Cordeliers (CRC), Université Pierre et Marie Curie - Paris 6 (UPMC)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Lausanne (UNIL), Medical Cell Biology, Universität Regensburg (UR), University of Fribourg, University of Zurich, Staub, Olivier
المصدر: Physiological Reports
Physiological Reports, Wiley, 2019, 7 (15), pp.e14177. ⟨10.14814/phy2.14177⟩
Physiological Reports, Vol 7, Iss 15, Pp n/a-n/a (2019)
Physiological reports, vol. 7, no. 15, pp. e14177مصطلحات موضوعية: Male, 10017 Institute of Anatomy, Physiology, [SDV]Life Sciences [q-bio], 030204 cardiovascular system & hematology, Plasma renin activity, lcsh:Physiology, chemistry.chemical_compound, 2737 Physiology (medical), 0302 clinical medicine, Aldosterone/pharmacology, Animals, Kidney/drug effects, Kidney/metabolism, Mice, Inbred C57BL, Nephrons/drug effects, Nephrons/metabolism, Nuclear Proteins/genetics, Phenotype, Protein-Serine-Threonine Kinases/metabolism, Sodium/metabolism, Transcription Factors/genetics, Blood pressure, blood volume, kidney, steroid hormone, MESH: Sodium, MESH: Animals, Threonine, Aldosterone, Original Research, Kidney, lcsh:QP1-981, Chemistry, Kinase, Nuclear Proteins, MESH: Transcription Factors, Cell biology, medicine.anatomical_structure, Regulatory Pathways, PIM1, 610 Medicine & health, Protein Serine-Threonine Kinases, MESH: Phenotype, MESH: Protein-Serine-Threonine Kinases, 03 medical and health sciences, MESH: Mice, Inbred C57BL, Physiology (medical), medicine, MESH: Nephrons, Serine/threonine-specific protein kinase, Sodium, MESH: Aldosterone, Nephrons, 1314 Physiology, MESH: Kidney, MESH: Male, 570 Life sciences, biology, MESH: Nuclear Proteins, 030217 neurology & neurosurgery, Homeostasis, Transcription Factors
وصف الملف: application/pdf; Spirli_et_al-2019-Physiological_Reports.pdf - application/pdf
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المؤلفون: Miguel Angel de la Fuente, Paul A. Anderson, Johannes Popow, Alexis A. Jourdain, Maria Simarro, Jean-Claude Martinou
المساهمون: Swiss National Science Foundation, Junta de Castilla y León
المصدر: UVaDOC. Repositorio Documental de la Universidad de Valladolid
instname
UVaDOC: Repositorio Documental de la Universidad de Valladolid
Universidad de Valladolid
Nucleic acids research, vol. 45, no. 19, pp. 10941-10947
Digital.CSIC. Repositorio Institucional del CSIC
Nucleic Acids Researchمصطلحات موضوعية: 0301 basic medicine, Mitochondrial DNA, RNA, Mitochondrial, Gene Expression Regulation, Humans, Mitochondrial Proteins/genetics, Mitochondrial Proteins/metabolism, Protein Serine-Threonine Kinases/genetics, Protein Serine-Threonine Kinases/metabolism, RNA/genetics, RNA/metabolism, RNA, Messenger/genetics, RNA, Messenger/metabolism, RNA-Binding Proteins/genetics, RNA-Binding Proteins/metabolism, RNA-binding protein, Protein Serine-Threonine Kinases, Mitochondrion, Biology, Ribosome assembly, Mitochondrial Proteins, Mitochondrial RNA, 03 medical and health sciences, 0302 clinical medicine, Genetics, RNA, Messenger, Survey and Summary, Regulation of gene expression, Messenger RNA, RNA-Binding Proteins, Proteins, RNA, Translation (biology), Cell biology, 030104 developmental biology, ARN mitocondrial, Proteínas, 030217 neurology & neurosurgery
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69bb511b150faf6e4c7dbd040aa3901e
https://doi.org/10.1093/nar/gkx772 -
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المؤلفون: Victor A. Neel, Seung-Hee Jo, G. Paolo Dotto, Maria-Giuseppina Procopio, Sandro Goruppi, Andrea Clocchiatti
المصدر: Cell Reports, Vol 20, Iss 10, Pp 2468-2479 (2017)
Cell reports, vol. 20, no. 10, pp. 2468-2479مصطلحات موضوعية: squamous cell carcinoma, 0301 basic medicine, autophagy, Stromal cell, cancer-associated fibroblast, Notch signaling pathway, Fluorescent Antibody Technique, Protein Serine-Threonine Kinases, Biology, Zinc Finger Protein GLI1, Article, General Biochemistry, Genetics and Molecular Biology, Mice, ULK3, 03 medical and health sciences, Cancer-Associated Fibroblasts, Downregulation and upregulation, GLI2, Animals, Humans, tumor microenvironment, Gene silencing, CAF, Autophagy/physiology, Cancer-Associated Fibroblasts/metabolism, Female, Fibroblasts/metabolism, Immunoglobulin J Recombination Signal Sequence-Binding Protein/metabolism, Protein-Serine-Threonine Kinases/genetics, Protein-Serine-Threonine Kinases/metabolism, Signal Transduction/genetics, Signal Transduction/physiology, Zinc Finger Protein GLI1/genetics, Zinc Finger Protein GLI1/metabolism, CSL/RBPJ, GLI, SCC, cancer stroma, lcsh:QH301-705.5, RBPJ, Autophagy, Fibroblasts, 030104 developmental biology, lcsh:Biology (General), Immunoglobulin J Recombination Signal Sequence-Binding Protein, Cancer research, Signal transduction, Signal Transduction
وصف الملف: application/pdf
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المؤلفون: Csaba Horváth, M.Saadeh Suleiman, Kristina Ferenczyova, Izabela Jarabicova, Tanya Ravingerova, Lucia Kindernay, Megan Young, Martin J. Lewis, Adriana Adameova
المصدر: International Journal of Molecular Sciences, Vol 22, Iss 7983, p 7983 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 15
Horvath, C, Young, M, Jarabicova, I, Kindernay, L, Ferenczyova, K, Ravingerova, T, Lewis, M, Suleiman, M S & Adameova, A 2021, ' Inhibition of Cardiac RIP3 Mitigates Early Reperfusion Injury and Calcium-Induced Mitochondrial Swelling without Altering Necroptotic Signalling ', International Journal of Molecular Sciences, vol. 22, no. 15, 7983 . https://doi.org/10.3390/ijms22157983مصطلحات موضوعية: Male, 0301 basic medicine, Myocardium/metabolism, medicine.disease_cause, Mitochondria, Heart, 0302 clinical medicine, Biology (General), myocardial ischemia/reperfusion, Spectroscopy, Calcium signaling, Chemistry, Inflammasome, General Medicine, Computer Science Applications, Cell biology, Receptor-Interacting Protein Serine-Threonine Kinases, 030220 oncology & carcinogenesis, Necroptosis, medicine.symptom, medicine.drug, Programmed cell death, Calcium/metabolism, QH301-705.5, Receptor-Interacting Protein Serine-Threonine Kinases/metabolism, necroptosis, Myocardial Reperfusion Injury, Inflammation, Article, Catalysis, Inorganic Chemistry, 03 medical and health sciences, Myocardial Reperfusion Injury/metabolism, medicine, Animals, Calcium Signaling, Rats, Wistar, Physical and Theoretical Chemistry, Protein kinase A, QD1-999, Molecular Biology, Myocardium, Organic Chemistry, medicine.disease, Mitochondria, Heart/metabolism, Rats, receptor-interacting protein kinase 3, 030104 developmental biology, Calcium, Reperfusion injury, Oxidative stress
وصف الملف: application/pdf
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المؤلفون: Jawahar Kopparam, Mauro Delorenzi, Etienne Meylan, Paolo Angelino, Nadine Zangger, Alessandra Piersigilli, Johanna Chiffelle
المصدر: Cell death and differentiation, vol. 24, no. 10, pp. 1761-1771
Cell Death and Differentiationمصطلحات موضوعية: STAT3 Transcription Factor, 0301 basic medicine, Original Paper, Gene knockdown, biology, Adenocarcinoma/metabolism, Cell Differentiation/physiology, Genes, ras/genetics, Humans, Lung Neoplasms/metabolism, Phosphorylation, Protein-Serine-Threonine Kinases/metabolism, Signal Transduction/physiology, Cancer, Lysyl oxidase, Cell Biology, medicine.disease, Proto-Oncogene Proteins p21(ras), Extracellular matrix, 03 medical and health sciences, 030104 developmental biology, HMGA2, Neoplasms, Extracellular, medicine, biology.protein, Cancer research, Adenocarcinoma, Lung cancer, Molecular Biology
وصف الملف: application/pdf
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المؤلفون: Florence Cordier, Nicolas Wolff, Henri Buc, Bertrand Raynal, Elouan Terrien, Muriel Delepierre, Alain Chaffotte, Florent Delhommel
المساهمون: Résonance Magnétique Nucléaire des Biomolécules, Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris], Cellule Pasteur UPMC, Institut Pasteur [Paris]-Sorbonne Université (SU), Biophysique Moléculaire (Plate-forme), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris], This work was supported by the Institut Pasteur and Institut Carnot Pasteur Maladies Infectieuses [grant number 13/10/120], and the Ministère de l’Enseignement Supérieur [grant number 883/2013 (to F.D.)]., We thank Jane Hardy and Terence Strick for careful proofreading of the manuscript and Patrick England for valuable discussions., Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP)-Sorbonne Université (SU), Institut Pasteur [Paris] (IP)
المصدر: Biochemical Journal
Biochemical Journal, Portland Press, 2015, 469 (1), pp.159-168. ⟨10.1042/BJ20141198⟩
Biochemical Journal, 2015, 469 (1), pp.159-168. ⟨10.1042/BJ20141198⟩مصطلحات موضوعية: Scaffold protein, MESH: Protein Structure, Quaternary, [SDV]Life Sciences [q-bio], Peptide binding, MESH: Protein Multimerization, Biochemistry, MESH: Protein Structure, Tertiary, MESH: Protein-Serine-Threonine Kinases / metabolism, 0302 clinical medicine, MESH: Nuclear Magnetic Resonance, Biomolecular, Tensin, MESH: Rabies virus / metabolism, MESH: Viral Proteins / chemistry, pre-steady-state kinetics, 0303 health sciences, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], biology, MESH: Molecular Dynamics Simulation, Cell biology, DLG1, Microtubule-Associated Proteins, Protein Binding, PDZ domain, MESH: Rabies virus / chemistry, protein–protein interactions, Molecular Dynamics Simulation, Protein Serine-Threonine Kinases, MESH: Protein-Serine-Threonine Kinases / chemistry, Viral Proteins, 03 medical and health sciences, MESH: Microtubule-Associated Proteins / chemistry, Humans, MESH: Protein Binding, PTEN, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Protein Structure, Quaternary, Nuclear Magnetic Resonance, Biomolecular, Molecular Biology, Protein kinase B, 030304 developmental biology, Serine/threonine-specific protein kinase, MESH: Humans, PDZ domains, Cell Biology, MESH: Viral Proteins / metabolism, Protein Structure, Tertiary, MESH: Microtubule-Associated Proteins / metabolism, Rabies virus, intradomain energetic connectivity, biology.protein, sense organs, Protein Multimerization, 030217 neurology & neurosurgery
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4686c21e9c3b7509080eb7a4c0a244
https://doi.org/10.1042/bj20141198
