المؤلفون: Rappold PM; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York., Vuong L; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York., Leibold J; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Medical Oncology and Pneumology (Internal Medicine VIII), University Hospital Tuebingen, Tuebingen, Germany.; DFG Cluster of Excellence 2180 Image-Guided and Functional Instructed Tumor Therapy (iFIT), University of Tuebingen, Tuebingen, Germany., Chakiryan NH; Department of Genitourinary Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida., Curry M; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York., Kuo F; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York., Sabio E; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York., Jiang H; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York., Nixon BG; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, New York., Liu M; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, New York.; Legend Biotech USA Inc., Upper Saddle River, New Jersey., Berglund AE; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida., Silagy AW; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York., Mascareno EA; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York., Golkaram M; Illumina, Inc., San Diego, California., Marker M; Novartis Oncology, New Hanover, New Jersey., Reising A; Novartis Oncology, New Hanover, New Jersey., Savchenko A; Novartis Oncology, New Hanover, New Jersey., Millholland J; Novartis Oncology, New Hanover, New Jersey., Chen YB; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York., Russo P; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York., Coleman J; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York., Reznik E; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York., Manley BJ; Department of Genitourinary Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.; Integrated Mathematical Oncology Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida., Ostrovnaya I; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York., Makarov V; Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, Ohio., DiNatale RG; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York., Blum KA; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York., Ma X; Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, Ohio., Chowell D; Department of Oncological Sciences, The Precision Immunology Institute, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York., Li MO; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, New York., Solit DB; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, New York., Lowe SW; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York., Chan TA; Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, Ohio.; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York., Motzer RJ; Department of Medicine, Genitourinary Oncology, Memorial Sloan Kettering Cancer Center, New York, New York., Voss MH; Department of Medicine, Genitourinary Oncology, Memorial Sloan Kettering Cancer Center, New York, New York., Hakimi AA; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.

المصدر: Cancer discovery [Cancer Discov] 2022 Oct 05; Vol. 12 (10), pp. 2308-2329.

نوع المنشور: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Renal Cell*/pathology , Kidney Neoplasms*/pathology, Animals ; Mice ; Adenosine A2 Receptor Antagonists ; Biomarkers, Tumor/genetics ; Inflammation ; Interleukin-6 ; Neoplasm Recurrence, Local/pathology ; Prognosis ; Tumor Microenvironment/genetics ; Humans

المؤلفون: Leibold J; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York., Ruscetti M; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York., Cao Z; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, New York, New York., Ho YJ; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York., Baslan T; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York., Zou M; Departments of Pharmacology, Urology, Medicine, Pathology and Cell Biology, and Systems Biology, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York., Abida W; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York., Feucht J; Center for Cell Engineering and Immunology Program, Memorial Sloan Kettering Cancer Center, New York, New York., Han T; Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, New York, New York.; Sandra and Edward Meyer Cancer Center, Department of Medicine, Weill Cornell Medicine, New York, New York., Barriga FM; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York., Tsanov KM; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York., Zamechek L; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York., Kulick A; Department of Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York., Amor C; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York., Tian S; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York., Rybczyk K; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York., Salgado NR; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York., Sánchez-Rivera FJ; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York., Watson PA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York., de Stanchina E; Department of Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York., Wilkinson JE; Department of Pathology, University of Michigan, Ann Arbor, Michigan., Dow LE; Sandra and Edward Meyer Cancer Center, Department of Medicine, Weill Cornell Medicine, New York, New York., Abate-Shen C; Departments of Pharmacology, Urology, Medicine, Pathology and Cell Biology, and Systems Biology, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York., Sawyers CL; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York. lowes@mskcc.org sawyersc@mskcc.org.; Howard Hughes Medical Institute, Chevy Chase, Maryland., Lowe SW; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York. lowes@mskcc.org sawyersc@mskcc.org.; Howard Hughes Medical Institute, Chevy Chase, Maryland.

المصدر: Cancer discovery [Cancer Discov] 2020 Jul; Vol. 10 (7), pp. 1038-1057. Date of Electronic Publication: 2020 May 06.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Prostatic Neoplasms/*genetics , Tissue Engineering/*methods , Wnt Signaling Pathway/*genetics, Animals ; Disease Models, Animal ; Female ; Humans ; Male ; Mice ; Neoplasm Metastasis