المؤلفون: Son S; College of Pharmacy, SungKyunKwan University, 300 Chonchon-dong, Jangan-gu, Suwon 440-746, Korea., Chae SY, Kim CW, Choi YG, Jung SY, Lee S, Lee KC

المصدر: Journal of medicinal chemistry [J Med Chem] 2009 Nov 12; Vol. 52 (21), pp. 6889-96.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Cholic Acids/*chemical synthesis , Hypoglycemic Agents/*chemical synthesis , Peptides/*chemical synthesis , Receptors, Glucagon/*agonists , Venoms/*chemical synthesis, Animals ; Cell Line, Tumor ; Cholic Acids/pharmacokinetics ; Cholic Acids/pharmacology ; Deoxycholic Acid/analogs & derivatives ; Deoxycholic Acid/chemical synthesis ; Deoxycholic Acid/pharmacokinetics ; Deoxycholic Acid/pharmacology ; Diabetes Mellitus, Type 2/drug therapy ; Exenatide ; Glucagon-Like Peptide-1 Receptor ; Glucose Tolerance Test ; Hydrophobic and Hydrophilic Interactions ; Hypoglycemic Agents/pharmacokinetics ; Hypoglycemic Agents/pharmacology ; In Vitro Techniques ; Islets of Langerhans/drug effects ; Islets of Langerhans/metabolism ; Lithocholic Acid/analogs & derivatives ; Lithocholic Acid/chemical synthesis ; Lithocholic Acid/pharmacokinetics ; Lithocholic Acid/pharmacology ; Male ; Mice ; Peptides/pharmacokinetics ; Peptides/pharmacology ; Protein Binding ; Radioligand Assay ; Rats ; Rats, Sprague-Dawley ; Serum Albumin/metabolism ; Structure-Activity Relationship ; Venoms/pharmacokinetics ; Venoms/pharmacology