المؤلفون: Singh A; Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University , Baltimore, Maryland 21205, United States., Venkannagari S; Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University , Baltimore, Maryland 21205, United States., Oh KH; Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University , Baltimore, Maryland 21205, United States., Zhang YQ; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States., Rohde JM; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States., Liu L; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States., Nimmagadda S; Departments of Radiology and Oncology, School of Medicine, Johns Hopkins University , Baltimore, Maryland 21205, United States., Sudini K; Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University , Baltimore, Maryland 21205, United States., Brimacombe KR; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States., Gajghate S; Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University , Baltimore, Maryland 21205, United States., Ma J; Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University , Baltimore, Maryland 21205, United States., Wang A; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States., Xu X; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States., Shahane SA; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States., Xia M; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States., Woo J; Department of Oncology, School of Medicine, Johns Hopkins University , Baltimore, Maryland 21205, United States., Mensah GA; Department of Pharmaceutical Sciences, Massachusetts College of Pharmacy and Health Sciences , Worcester, Massachusetts 01608, United States., Wang Z; Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University , Baltimore, Maryland 21205, United States., Ferrer M; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States., Gabrielson E; Department of Oncology, School of Medicine, Johns Hopkins University , Baltimore, Maryland 21205, United States., Li Z; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States., Rastinejad F; Metabolic Signaling and Disease Program, Sanford-Burnham Medical Research Institute , Orlando, Florida 32827, United States., Shen M; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States., Boxer MB; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States., Biswal S; Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University , Baltimore, Maryland 21205, United States.; Department of Oncology, School of Medicine, Johns Hopkins University , Baltimore, Maryland 21205, United States.

المصدر: ACS chemical biology [ACS Chem Biol] 2016 Nov 18; Vol. 11 (11), pp. 3214-3225. Date of Electronic Publication: 2016 Oct 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Drug Resistance, Neoplasm*, Carcinoma, Non-Small-Cell Lung/*drug therapy , Kelch-Like ECH-Associated Protein 1/*genetics , Lung Neoplasms/*drug therapy , NF-E2-Related Factor 2/*antagonists & inhibitors, Carcinoma, Non-Small-Cell Lung/metabolism ; Carcinoma, Non-Small-Cell Lung/pathology ; Cell Line, Tumor ; Humans ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology

المؤلفون: Kumar V; Laboratory of Synthetic Chemistry, SAIC Frederick, Inc., National Cancer Institute at Frederick, Frederick, Maryland 21702, United States., Kumar S, Hassan M, Wu H, Thimmulappa RK, Kumar A, Sharma SK, Parmar VS, Biswal S, Malhotra SV

المصدر: Journal of medicinal chemistry [J Med Chem] 2011 Jun 23; Vol. 54 (12), pp. 4147-59. Date of Electronic Publication: 2011 May 19.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Bronchi/*drug effects , Chalcones/*chemical synthesis , Enzyme Activators/*chemical synthesis , Epithelial Cells/*drug effects , NF-E2-Related Factor 2/*metabolism, Animals ; Bronchi/cytology ; Bronchi/metabolism ; Cell Line ; Cell Survival/drug effects ; Chalcones/chemistry ; Chalcones/pharmacology ; Enzyme Activators/chemistry ; Enzyme Activators/pharmacology ; Epithelial Cells/metabolism ; Glutamate-Cysteine Ligase/biosynthesis ; Glutamate-Cysteine Ligase/genetics ; Heme Oxygenase-1/biosynthesis ; Heme Oxygenase-1/genetics ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; NAD(P)H Dehydrogenase (Quinone)/biosynthesis ; NAD(P)H Dehydrogenase (Quinone)/genetics ; Oxidation-Reduction ; Quantitative Structure-Activity Relationship ; Reactive Oxygen Species/metabolism ; Stereoisomerism ; Transcription, Genetic