المؤلفون: Browne LJ; Research Department, CIBA-GEIGY Corporation, Summit, New Jersey 07901., Gude C, Rodriguez H, Steele RE, Bhatnager A

المصدر: Journal of medicinal chemistry [J Med Chem] 1991 Feb; Vol. 34 (2), pp. 725-36.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN: 0022-2623 (Print) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Aromatase Inhibitors*, Antineoplastic Agents/*chemical synthesis , Estrogen Antagonists/*chemical synthesis , Imidazoles/*therapeutic use , Nitriles/*therapeutic use, Animals ; Antineoplastic Agents/therapeutic use ; Chemical Phenomena ; Chemistry ; Estrogen Antagonists/therapeutic use ; Fadrozole ; Female ; Humans ; Rats ; Structure-Activity Relationship

المؤلفون: Gruenfeld N, Stanton JL, Yuan AM, Ebetino FH, Browne LJ, Gude C, Huebner CF

المصدر: Journal of medicinal chemistry [J Med Chem] 1983 Sep; Vol. 26 (9), pp. 1277-82.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN: 0022-2623 (Print) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Angiotensin-Converting Enzyme Inhibitors*, Indoles/*chemical synthesis, Animals ; Binding Sites ; Blood Pressure/drug effects ; Indoles/pharmacology ; Magnetic Resonance Spectroscopy ; Rats ; Rats, Inbred Strains ; Zinc/metabolism

المؤلفون: Ford NF, Browne LJ, Campbell T, Gemenden C, Goldstein R, Gude C, Wasley JW

المصدر: Journal of medicinal chemistry [J Med Chem] 1985 Feb; Vol. 28 (2), pp. 164-70.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN: 0022-2623 (Print) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Cytochrome P-450 Enzyme System* , Intramolecular Oxidoreductases*, Imidazoles/*chemical synthesis , Oxidoreductases/*antagonists & inhibitors , Pyridines/*chemical synthesis , Thromboxane A2/*biosynthesis , Thromboxane-A Synthase/*antagonists & inhibitors , Thromboxanes/*biosynthesis, Animals ; Blood Platelets/enzymology ; Cattle ; Epoprostenol/biosynthesis ; Epoprostenol/metabolism ; Humans ; Imidazoles/pharmacology ; Male ; Prostaglandin-Endoperoxide Synthases/metabolism ; Pyridines/pharmacology ; Sheep ; Structure-Activity Relationship