المؤلفون: Schwartz-Duval, Aaron S., Mackeyev, Yuri, Mahmud, Iqbal, Lorenzi, Philip L., Gagea, Mihai, Krishnan, Sunil, Sokolov, Konstantin V.

المصدر: ACS Nano; 1/23/2024, Vol. 18 Issue 3, p1865-1881, 17p

المؤلفون: Purwaha, Preeti, Silva, Leslie P., Hawke, David H., Weinstein, John N., Lorenzi, Philip L.

المصدر: Analytical Chemistry; 6/17/2014, Vol. 86 Issue 12, p5633-5637, 5p

المؤلفون: Silva, Leslie P., Lorenzi, Philip L., Purwaha, Preeti, Valeda Yong, Hawke, David H., Weinstein, John N.

المصدر: Analytical Chemistry; 10/15/2013, Vol. 85 Issue 20, p9536-9542, 7p

المؤلفون: Lubkowski J; Macromolecular Crystallography Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States., Vanegas J; Department of Physics, The University of Vermont, Burlington, Vermont 05408, United States., Chan WK; Department of Bioinformatics and Computational Biology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, United States., Lorenzi PL; Department of Bioinformatics and Computational Biology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, United States., Weinstein JN; Department of Bioinformatics and Computational Biology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, United States., Sukharev S; Department of Biology, University of Maryland, College Park, Maryland 20742, United States., Fushman D; Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20742, United States., Rempe S; Center for Biological and Engineering Sciences, Sandia National Laboratories, Albuquerque, New Mexico 87185, United States., Anishkin A; Department of Biology, University of Maryland, College Park, Maryland 20742, United States., Wlodawer A; Macromolecular Crystallography Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States.

المصدر: Biochemistry [Biochemistry] 2020 May 26; Vol. 59 (20), pp. 1927-1945. Date of Electronic Publication: 2020 May 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4995 (Electronic) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE

مواضيع طبية MeSH: Biocatalysis*, Asparaginase/*metabolism , Dickeya chrysanthemi/*enzymology , Escherichia coli/*enzymology, Asparaginase/chemistry ; Crystallography, X-Ray ; Hydrolysis ; Kinetics ; Models, Molecular

المؤلفون: Song X; Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109, USA., Lorenzi PL, Landowski CP, Vig BS, Hilfinger JM, Amidon GL

المصدر: Molecular pharmaceutics [Mol Pharm] 2005 Mar-Apr; Vol. 2 (2), pp. 157-67.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print Cited Medium: Print ISSN: 1543-8384 (Print) Linking ISSN: 15438384 NLM ISO Abbreviation: Mol Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Amino Acids/*pharmacology , Antineoplastic Agents/*pharmacology , Deoxycytidine/*analogs & derivatives , Prodrugs/*chemistry , Symporters/*chemistry, Amino Acids/chemistry ; Antineoplastic Agents/chemistry ; Biological Transport ; Caco-2 Cells ; Cell Line, Tumor ; Chromatography, High Pressure Liquid ; Cytidine Deaminase/chemistry ; Cytidine Deaminase/metabolism ; Deoxycytidine/pharmacokinetics ; Deoxycytidine/pharmacology ; Dipeptides/pharmacokinetics ; Drug Screening Assays, Antitumor/methods ; HeLa Cells ; Humans ; Hydrolysis ; Inhibitory Concentration 50 ; Peptide Transporter 1 ; Peptides/chemistry ; Gemcitabine

المؤلفون: Song X; Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109-1065, USA., Vig BS, Lorenzi PL, Drach JC, Townsend LB, Amidon GL

المصدر: Journal of medicinal chemistry [J Med Chem] 2005 Feb 24; Vol. 48 (4), pp. 1274-7.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN: 0022-2623 (Print) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Amino Acids/*chemical synthesis , Antiviral Agents/*chemical synthesis , Benzimidazoles/*chemical synthesis , Prodrugs/*chemical synthesis , Ribonucleosides/*chemical synthesis , Symporters/*metabolism, Amino Acids/chemistry ; Amino Acids/pharmacology ; Antiviral Agents/chemistry ; Antiviral Agents/pharmacology ; Benzimidazoles/chemistry ; Benzimidazoles/pharmacology ; Dipeptides/antagonists & inhibitors ; Dipeptides/metabolism ; Esters ; HeLa Cells ; Humans ; Peptide Transporter 1 ; Prodrugs/chemistry ; Prodrugs/pharmacology ; Ribonucleosides/chemistry ; Ribonucleosides/pharmacology ; Stereoisomerism ; Structure-Activity Relationship