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المؤلفون: Ruoxing Lei, Nicole A. Repina, Sanjay Kumar, Dempsey Garrett, Kelly C Y Wong, David V. Schaffer, Kayla J. Wolf, Erin A Akins, Andreas Stahl
المصدر: ACS Biomater Sci Eng
مصطلحات موضوعية: Durotaxis, Chemistry, 0206 medical engineering, Biomedical Engineering, Hydrogels, 02 engineering and technology, Matrix (biology), 021001 nanoscience & nanotechnology, Mechanotransduction, Cellular, 020601 biomedical engineering, Article, Haptotaxis, Extracellular Matrix, Biomaterials, Extracellular matrix, Mechanobiology, Self-healing hydrogels, Cell Adhesion, Biophysics, Humans, Hyaluronic Acid, Mechanotransduction, 0210 nano-technology, Cell adhesion
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المصدر: Olesen, S V, Rajabi, N, Svensson, B, Olsen, C A & Madsen, A S 2018, ' An NAD +-dependent sirtuin depropionylase and deacetylase (Sir2La) from the probiotic bacterium Lactobacillus acidophilus NCFM ', Biochemistry, vol. 57, no. 26, pp. 3903-3915 . https://doi.org/10.1021/acs.biochem.8b00306
مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, biology, Nad dependent, Probiotic bacterium, Metabolism, Biochemistry, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Enzyme, Lactobacillus acidophilus, chemistry, Sirtuin, biology.protein, NAD+ kinase, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المؤلفون: Andreas Stahl Madsen, Ana Colaço, Alex Maolanon, Betül Kitir, Christian A. Olsen, Peter Fristrup, Ragnhild Gaard Ohm
المصدر: Biochemistry. 56:5134-5146
مصطلحات موضوعية: 0301 basic medicine, Macrocyclic Compounds, Antineoplastic Agents, Chemistry Techniques, Synthetic, 01 natural sciences, Biochemistry, Chemical synthesis, Histone Deacetylases, Romidepsin, Structure-Activity Relationship, 03 medical and health sciences, Nonribosomal peptide, medicine, Humans, Structure–activity relationship, Prodrugs, Epigenetics, chemistry.chemical_classification, Biological Products, Dose-Response Relationship, Drug, biology, 010405 organic chemistry, Small molecule, Recombinant Proteins, 3. Good health, 0104 chemical sciences, Histone Deacetylase Inhibitors, Kinetics, Zinc, 030104 developmental biology, Histone, chemistry, biology.protein, Histone deacetylase, HeLa Cells, medicine.drug
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المؤلفون: Andreas Stahl Madsen, Matthias Schiedel, Manfred Jung, Christian A. Olsen, Iacopo Galleano
المصدر: Journal of Medicinal Chemistry. 59:1021-1031
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Lysine, Drug Evaluation, Preclinical, Suramin, SIRT2, 01 natural sciences, Substrate Specificity, Acylation, Structure-Activity Relationship, 03 medical and health sciences, Sirtuin 2, Acetamides, Drug Discovery, Transcriptional regulation, Humans, Structure–activity relationship, Enzyme Inhibitors, Fluorescent Dyes, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, biology, 010405 organic chemistry, Chemistry, Small molecule, 0104 chemical sciences, Thiazoles, 030104 developmental biology, Enzyme, Biochemistry, Sirtuin, biology.protein, Molecular Medicine
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المؤلفون: Andreas Stahl Madsen, Jesper Wengel
المصدر: Madsen, A S & Wengel, J 2012, ' Oligonucleotides with 1,4-dioxane-based nucleotide monomers ', Journal of Organic Chemistry, vol. 77, no. 8, pp. 3878-86 . https://doi.org/10.1021/jo300222q
مصطلحات موضوعية: chemistry.chemical_classification, Sugar phosphates, Molecular Structure, Molecular model, Nucleotides, Oligonucleotide, Stereochemistry, Organic Chemistry, Oligonucleotides, 1,4-Dioxane, Dioxanes, chemistry.chemical_compound, Monomer, chemistry, Nucleic Acid Conformation, Nucleotide, A-DNA, DNA
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المصدر: Kumar, S T, Madsen, A S, Wengel, J & Hrdlicka, P J 2006, ' Synthesis and Hybridization Studies of 2'-Amino-a-L-LNA and a Tetracyclic "Locked LNA" ', Journal of Organic Chemistry, vol. 71, no. 11, pp. 4188-4201 . https://doi.org/10.1021/jo060331f
مصطلحات موضوعية: Phosphoramidite, Molecular Structure, Bicyclic molecule, Chemistry, Stereochemistry, Organic Chemistry, Diol, Nucleobase, Thymine, chemistry.chemical_compound, Thymidine Monophosphate, Nucleic acid, Protecting group, Nucleoside
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المؤلفون: Iacopo Galleano, Manfred Jung, Andreas Stahl Madsen, Christian A. Olsen, Matthias Schiedel
المصدر: Journal of Medicinal Chemistry. 59:2847-2847
مصطلحات موضوعية: 0301 basic medicine, biology, Chemistry, Stereochemistry, Substrate (chemistry), Carbon-13 NMR, 01 natural sciences, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, 030104 developmental biology, Drug Discovery, Sirtuin, biology.protein, Proton NMR, Molecular Medicine, NAD+ kinase