يعرض 1 - 5 نتائج من 5 نتيجة بحث عن '"Shi-Liang Huang"', وقت الاستعلام: 0.77s تنقيح النتائج
  1. 1
    Design, Synthesis, and Evaluation of New Sugar-Substituted Imidazole Derivatives as Selective c-MYC Transcription Repressors Targeting the Promoter G-Quadruplex

    المؤلفون: Mao-Lin Li, Jing-Mei Yuan, Hao Yuan, Bi-Han Wu, Shi-Liang Huang, Qing-Jiang Li, Tian-Miao Ou, Hong-Gen Wang, Jia-Heng Tan, Ding Li, Shuo-Bin Chen, Zhi-Shu Huang

    المصدر: Journal of Medicinal Chemistry. 65:12675-12700

    مصطلحات موضوعية: Drug Discovery, Molecular Medicine

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e5266df396b14895123914afea378ad4
    https://doi.org/10.1021/acs.jmedchem.2c00467

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  2. 2
    Discovery of a Novel G-Quadruplex and Histone Deacetylase (HDAC) Dual-Targeting Agent for the Treatment of Triple-Negative Breast Cancer

    المؤلفون: Xin-Chen Jiang, Fang-Hai Tu, Li-Yuan Wei, Bo-Zheng Wang, Hao Yuan, Jing-Mei Yuan, Yong Rao, Shi-Liang Huang, Qing-Jiang Li, Tian-Miao Ou, Hong-Gen Wang, Jia-Heng Tan, Shuo-Bin Chen, Zhi-Shu Huang

    المصدر: Journal of Medicinal Chemistry. 65:12346-12366

    مصطلحات موضوعية: Histone Deacetylase Inhibitors, Zinc, Cell Line, Tumor, Drug Discovery, Humans, Molecular Medicine, Antineoplastic Agents, Apoptosis, Triple Negative Breast Neoplasms, DNA, Xenograft Model Antitumor Assays, Histone Deacetylases, Cell Proliferation

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ee936cf4c88cd1bc4652ea3f6093fb
    https://doi.org/10.1021/acs.jmedchem.2c01058

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  3. 3
    Design, Synthesis, and Evaluation of New Quinazolinone Derivatives that Inhibit Bloom Syndrome Protein (BLM) Helicase, Trigger DNA Damage at the Telomere Region, and Synergize with PARP Inhibitors

    المؤلفون: Shi-Liang Huang, Qi-Kun Yin, Jia-En Wang, Honggen Wang, Ding Li, Chen-Xi Wang, Jia-Heng Tan, Zhi-Shu Huang, Yao-Hao Xu, Yong Rao, Zi-Lin Zhang, Shuo-Bin Chen, Tian-Miao Ou, Jia-Li Tu, Qingjiang Li

    المصدر: Journal of Medicinal Chemistry. 63:9752-9772

    مصطلحات موضوعية: Models, Molecular, congenital, hereditary, and neonatal diseases and abnormalities, Protein Conformation, DNA damage, Poly ADP ribose polymerase, Apoptosis, Chemistry Techniques, Synthetic, Poly(ADP-ribose) Polymerase Inhibitors, 01 natural sciences, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, Humans, Polymerase, Cell Proliferation, Quinazolinones, 030304 developmental biology, 0303 health sciences, RecQ Helicases, biology, urogenital system, Chemistry, nutritional and metabolic diseases, Helicase, Drug Synergism, Telomere, HCT116 Cells, 0104 chemical sciences, Cell biology, 010404 medicinal & biomolecular chemistry, Bloom syndrome protein, Drug Design, Cancer cell, biology.protein, Molecular Medicine, DNA, DNA Damage

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f21267762456ab0e27c8001c4c005bf
    https://doi.org/10.1021/acs.jmedchem.0c00917

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  4. 4
    Energetic Cocrystal, Ionic Salt, and Coordination Polymer of a Perchlorate Free High Energy Density Oxidizer: Influence of pKa Modulation on Their Formation

    المؤلفون: Huang Jinglun, Gui-Juan Fan, Qing Ma, Fude Nie, Longyu Liao, Shi-Liang Huang, Huanchang Lu

    المصدر: Crystal Growth & Design. 19:714-723

    مصطلحات موضوعية: chemistry.chemical_classification, Organic base, 010405 organic chemistry, Coordination polymer, Inorganic chemistry, Salt (chemistry), Ionic bonding, General Chemistry, 010402 general chemistry, Condensed Matter Physics, 01 natural sciences, Cocrystal, 0104 chemical sciences, Dissociation constant, chemistry.chemical_compound, Perchlorate, chemistry, General Materials Science, Organic acid

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e58e68250cf0a4a9e3d825df1e7d62f4
    https://doi.org/10.1021/acs.cgd.8b01293

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  5. 5
    Synthesis of Benzofused N-Heterocycles via Rh(III)-Catalyzed Direct Benzannulation with 1,3-Dienes

    المؤلفون: Jia-Qiang Wu, Hui Gao, Shi-Liang Huang, Honggen Wang, Xianxing Jiang, Bai Li, Shang-Shi Zhang, Chu-Jun Zhou

    المصدر: ACS Catalysis. 9:556-564

    مصطلحات موضوعية: 010405 organic chemistry, Chemistry, chemistry.chemical_element, General Chemistry, 010402 general chemistry, Ring (chemistry), 01 natural sciences, Combinatorial chemistry, Catalysis, 0104 chemical sciences, Rhodium, De novo synthesis, chemistry.chemical_compound, Functional importance, Benzene derivatives, Benzene

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::457dccf2c0abe04c0531774cff2c3ec8
    https://doi.org/10.1021/acscatal.8b03595

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