يعرض 1 - 10 نتائج من 72 نتيجة بحث عن '"Acetylcholine receptor"', وقت الاستعلام: 1.70s تنقيح النتائج
  1. 1
    Oligoarginine Peptides, a New Family of Nicotinic Acetylcholine Receptor Inhibitors

    المؤلفون: Ia Iagorshvili, Victor I. Tsetlin, Ramaz Katsarava, Ekaterina N. Spirova, Dmitry S. Lebedev, Igor E. Kasheverov, Elizaveta Yu. Tufanova, Natalia S. Egorova, Nikita D. Timofeev, Elena V. Kryukova, Nino Zavradashvili, Igor Ivanov, Andrei E. Siniavin, Marios Zouridakis, Socrates J. Tzartos, Denis S. Kudryavtsev

    المصدر: Molecular Pharmacology. 96:664-673

    مصطلحات موضوعية: 0301 basic medicine, Arginine, Protein subunit, Nicotinic Antagonists, Receptors, Nicotinic, complex mixtures, Mice, Xenopus laevis, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, mental disorders, Radioligand, Animals, Humans, Conotoxin, Binding site, Acetylcholine receptor, Pharmacology, Dose-Response Relationship, Drug, Chemistry, musculoskeletal, neural, and ocular physiology, Nicotinic acetylcholine receptor, 030104 developmental biology, Nicotinic agonist, nervous system, Biochemistry, Molecular Medicine, Female, sense organs, Peptides, 030217 neurology & neurosurgery

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5ca78c83ee18a3a5feeb9828fc555c2
    https://doi.org/10.1124/mol.119.117713

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  2. 2
    M1and M2Muscarinic Receptor Subtypes Regulate Antidepressant-Like Effects of the Rapidly Acting Antidepressant Scopolamine

    المؤلفون: Graham N. Wishart, Richard E. Higgs, Christian C. Felder, Jeffrey M. Witkin, Vladimir Tolstikov, Ming-Shang Kuo, Wesley H. Anderson, Beverly A. Heinz, John T. Catlow, Alexander Nikolayev, Xia Li, Douglas A. Schober, Carl D Overshiner

    المصدر: Journal of Pharmacology and Experimental Therapeutics. 351:448-456

    مصطلحات موضوعية: Male, medicine.medical_specialty, Scopolamine, Muscarinic Antagonists, Motor Activity, Pharmacology, Imipramine, Rats, Sprague-Dawley, Mice, Internal medicine, Muscarinic acetylcholine receptor, medicine, Muscarinic acetylcholine receptor M4, Animals, Receptor, Swimming, Mice, Knockout, Receptor, Muscarinic M2, Chemistry, Receptor, Muscarinic M1, Antagonist, Brain, Muscarinic acetylcholine receptor M2, Muscarinic acetylcholine receptor M1, Pirenzepine, Antidepressive Agents, Rats, Mice, Inbred C57BL, Endocrinology, Molecular Medicine, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12828a04885b8647fb9bb921e3096fc0
    https://doi.org/10.1124/jpet.114.216804

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  3. 3
    Nicotine Dependence Reveals Distinct Responses from Neurons and Their Resident Nicotinic Receptors in Medial Habenula

    المؤلفون: J. Michael McIntosh, Pei Yu Shih, Ryan M. Drenan

    المصدر: Molecular Pharmacology. 88:1035-1044

    مصطلحات موضوعية: Nicotine, Interpeduncular nucleus, Receptors, Nicotinic, Mice, Organ Culture Techniques, Slice preparation, Pregnancy, medicine, Animals, Receptor, Acetylcholine receptor, Mice, Knockout, Neurons, Pharmacology, Habenula, Chemistry, musculoskeletal, neural, and ocular physiology, Tobacco Use Disorder, Articles, Anatomy, Mice, Inbred C57BL, Electrophysiology, Nicotinic agonist, nervous system, Molecular Medicine, Female, sense organs, Neuroscience, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f0d19f90d332ff1fd9e1b262a78fb5
    https://doi.org/10.1124/mol.115.101444

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  4. 4
    Menthol Enhances the Desensitization of Human α3β4 Nicotinic Acetylcholine Receptors

    المؤلفون: Hoai T. Ton, Brittany L. Aguilar, Kenneth J. Kellar, Thao T. Olson, Gerard P. Ahern, Amanda E. Smart

    المصدر: Molecular Pharmacology. 88:256-264

    مصطلحات موضوعية: Nicotine, Sensory Receptor Cells, Pyridines, Cholinergic Agonists, Receptors, Nicotinic, Pharmacology, Ion Channels, Mice, chemistry.chemical_compound, Allosteric Regulation, Desensitization (telecommunications), medicine, TRPM8, Animals, Humans, Cells, Cultured, Articles, Bridged Bicyclo Compounds, Heterocyclic, Acetylcholine, Mice, Inbred C57BL, Menthol, Nicotinic acetylcholine receptor, HEK293 Cells, Nicotinic agonist, chemistry, Epibatidine, Molecular Medicine, Nodose Ganglion, Signal Transduction, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::017e982ddf78c3c04895bef53cd35ccc
    https://doi.org/10.1124/mol.115.098285

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  5. 5
    Rapid Throughput Analysis Demonstrates that Chemicals with Distinct Seizurogenic Mechanisms Differentially Alter Ca2+ Dynamics in Networks Formed by Hippocampal Neurons in Culture

    المؤلفون: Yanjun Cui, Pamela J. Lein, Xiaohan Zou, Zhengyu Cao, Isaac N. Pessah, Susan Hulsizer, Heike Wulff

    المصدر: Molecular pharmacology, vol 87, iss 4
    Cao, Z; Zou, X; Cui, Y; Hulsizer, S; Lein, PJ; Wulff, H; et al.(2015). Rapid throughput analysis demonstrates that chemicals with distinct seizurogenic mechanisms differentially alter Ca2+dynamics in networks formed by hippocampal neurons in culture. Molecular Pharmacology, 87(4), 595-605. doi: 10.1124/mol.114.096701. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/6x00n7fh

    مصطلحات موضوعية: Agonist, Kainic acid, medicine.drug_class, Cells, Kainate receptor, Muscarinic Agonists, Pharmacology, Inbred C57BL, Lamotrigine, Hippocampus, Mice, chemistry.chemical_compound, Receptors, Kainic Acid, Seizures, Receptors, Muscarinic acetylcholine receptor, Potassium Channel Blockers, medicine, Animals, 2.1 Biological and endogenous factors, Channel blocker, Pharmacology & Pharmacy, 4-Aminopyridine, Aetiology, Cells, Cultured, Neurons, Cultured, Kainic Acid, Triazines, Chemistry, Neurosciences, Articles, Pharmacology and Pharmaceutical Sciences, High-Throughput Screening Assays, Mice, Inbred C57BL, Pilocarpine, Competitive antagonist, Neurological, CNQX, Biophysics, Molecular Medicine, Calcium, Anticonvulsants, Biochemistry and Cell Biology, Nerve Net, medicine.drug

    وصف الملف: application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f55072c3f566abb87b0f1680d0c7d10
    https://doi.org/10.1124/mol.114.096701

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  6. 6
    Effects of the Novel α7 Nicotinic Acetylcholine Receptor Agonist ABT-107 on Sensory Gating in DBA/2 Mice: Pharmacodynamic Characterization

    المؤلفون: Richard J. Radek, Karen E. Stevens, Robert S. Bitner, Holly M. Robb, Murali Gopalakrishnan

    المصدر: Journal of Pharmacology and Experimental Therapeutics. 343:736-745

    مصطلحات موضوعية: Agonist, Nicotine, Quinuclidines, Indoles, Time Factors, alpha7 Nicotinic Acetylcholine Receptor, medicine.drug_class, Gating, Receptors, Nicotinic, Pharmacology, Hippocampus, Drug Administration Schedule, Mice, chemistry.chemical_compound, medicine, Animals, Anesthesia, Nicotinic Agonists, Methyllycaconitine, Sensory gating, Dose-Response Relationship, Drug, Chemistry, Antagonist, Sensory Gating, Nicotinic acetylcholine receptor, medicine.anatomical_structure, Acoustic Stimulation, Mice, Inbred DBA, Pharmacodynamics, Evoked Potentials, Auditory, Molecular Medicine, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e67e0f6e05db6cb6d6c3618001093525
    https://doi.org/10.1124/jpet.112.197970

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  7. 7
    Synthesis of Selective Agonists for the α7 Nicotinic Acetylcholine Receptor with In Situ Click-Chemistry on Acetylcholine-Binding Protein Templates

    المؤلفون: Kwok-Yiu Ho, K. Barry Sharpless, Neil P. Grimster, Mikael Dufouil, Todd T. Talley, Kimberly Gomez, Palmer Taylor, Valery V. Fokin, John G. Yamauchi, Akos Nemecz, Joseph R. Fotsing

    المصدر: Molecular Pharmacology. 82:687-699

    مصطلحات موضوعية: Azides, alpha7 Nicotinic Acetylcholine Receptor, Stereochemistry, Nicotinic Antagonists, Receptors, Nicotinic, Cell Line, Mice, Radioligand Assay, Structure-Activity Relationship, Acetylcholine binding, chemistry.chemical_compound, Aplysia, Animals, Humans, Structure–activity relationship, Nicotinic Agonists, Nicotinic Antagonist, Ion channel, Lymnaea, Acetylcholine receptor, Pharmacology, Chemistry, Stereoisomerism, Tropane, Articles, Triazoles, Nicotinic agonist, nervous system, Alkynes, Mutation, Click chemistry, Molecular Medicine, Click Chemistry, Carrier Proteins, Tropanes

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d046e32717174debae934038c192e2e7
    https://doi.org/10.1124/mol.112.080291

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  8. 8
    Increased Nicotinic Acetylcholine Receptor Protein Underlies Chronic Nicotine-Induced Up-Regulation of Nicotinic Agonist Binding Sites in Mouse Brain

    المؤلفون: Allan C. Collins, John A. Cooper, Robert Brown, Michael J. Marks, Jon Lindstrom, Tristan D. McClure-Begley, Paul Whiteaker, Outi Salminen

    المصدر: Journal of Pharmacology and Experimental Therapeutics. 337:187-200

    مصطلحات موضوعية: Male, Agonist, Nicotine, medicine.drug_class, Immunoprecipitation, Receptors, Nicotinic, Pharmacology, Mice, Neuropharmacology, medicine, Animals, Nicotinic Agonists, Binding site, Acetylcholine receptor, Mice, Knockout, Binding Sites, Chemistry, Brain, Up-Regulation, Mice, Inbred C57BL, Nicotinic acetylcholine receptor, Nicotinic agonist, Epibatidine, Molecular Medicine, Female, sense organs, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3ce46511b8870969390308519d206e
    https://doi.org/10.1124/jpet.110.178236

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  9. 9
    Characterization of 2-[[4-Fluoro-3-(trifluoromethyl)phenyl]amino]-4-(4-pyridinyl)-5-thiazolemethanol (JNJ-1930942), a Novel Positive Allosteric Modulator of the α7 Nicotinic Acetylcholine Receptor

    المؤلفون: Hanne Verachtert, Anne S. J. Lesage, Erik De Prins, Lijun Zheng, Jan Willem Thuring, Luc Peeters, Ine Vandenberk, Karen E. Stevens, Theo Dinklo, Hilde Lavreysen, Claire Mackie, Hamdy Shaban, Greet Meulders, Christopher Grantham

    المصدر: Journal of Pharmacology and Experimental Therapeutics. 336:560-574

    مصطلحات موضوعية: Male, Allosteric modulator, alpha7 Nicotinic Acetylcholine Receptor, Cell Survival, Pyridines, Long-Term Potentiation, Receptors, Nicotinic, Pharmacology, Neurotransmission, Hippocampal formation, Hippocampus, Synaptic Transmission, Rats, Sprague-Dawley, Bridged Bicyclo Compounds, Mice, chemistry.chemical_compound, Allosteric Regulation, medicine, Animals, Humans, Nicotinic Agonists, Cells, Cultured, Methyllycaconitine, Chemistry, Dentate gyrus, Long-term potentiation, Rats, Thiazoles, Nicotinic acetylcholine receptor, Mice, Inbred DBA, Benzamides, Evoked Potentials, Auditory, Molecular Medicine, Calcium, Acetylcholine, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e289ed5c5cc48ab7d5d01a1cdde46957
    https://doi.org/10.1124/jpet.110.173245

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  10. 10
    The M2-Muscarinic Receptor Inhibits the Development of Streptozotocin-Induced Neuropathy in Mouse Urinary Bladder

    المؤلفون: Kirk J Pak, Rennolds S. Ostrom, Frederick J. Ehlert, Minoru Matsui

    المصدر: Journal of Pharmacology and Experimental Therapeutics. 335:239-248

    مصطلحات موضوعية: Blood Glucose, Male, medicine.medical_specialty, Muscarinic Antagonists, In Vitro Techniques, Biology, urologic and male genital diseases, Streptozocin, Mice, Adenosine Triphosphate, Internal medicine, Muscarinic acetylcholine receptor, medicine, Animals, Urinary Bladder, Neurogenic, Urothelium, Receptor, Mice, Knockout, Pharmacology, Receptor, Muscarinic M2, Antibiotics, Antineoplastic, Urinary bladder, Body Weight, Purinergic receptor, Isoproterenol, Muscle, Smooth, Muscarinic acetylcholine receptor M2, Organ Size, Adrenergic beta-Agonists, Streptozotocin, Electric Stimulation, female genital diseases and pregnancy complications, Mice, Inbred C57BL, Endocrine and Diabetes, medicine.anatomical_structure, Endocrinology, Hyperglycemia, Molecular Medicine, Cholinergic, Algorithms, Muscle Contraction, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba445dae41eb4d2415b51470f711bdd
    https://doi.org/10.1124/jpet.110.169995

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