المؤلفون: Serttas R; Department of Medical Biology, School of Medicine, Trakya University, Balkan Campus, 22030, Edirne, Turkey., Erdogan S; Department of Medical Biology, School of Medicine, Trakya University, Balkan Campus, 22030, Edirne, Turkey.

المصدر: Anti-cancer agents in medicinal chemistry [Anticancer Agents Med Chem] 2023; Vol. 23 (17), pp. 1958-1965.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: Netherlands NLM ID: 101265649 Publication Model: Print Cited Medium: Internet ISSN: 1875-5992 (Electronic) Linking ISSN: 18715206 NLM ISO Abbreviation: Anticancer Agents Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Ribonucleotide Reductases*/pharmacology , Ribonucleotide Reductases*/therapeutic use , Prostatic Neoplasms*/metabolism, Male ; Humans ; Docetaxel/pharmacology ; Docetaxel/therapeutic use ; Apoptosis ; Endoplasmic Reticulum Stress ; Cell Line, Tumor

المؤلفون: Iman M, Khansefid Z, Davood A; Medicinal Chemistry, Department of Medicinal Chemistry, Pharmaceutical Sciences Branch, Islamic Azad University, Tehran, 19419, Iran; Postal address: No 99, Yakhchal Street, Shariatie ave. Tehran, 19419, Iran. adavood2001@yahoo.com.

المصدر: Recent patents on anti-cancer drug discovery [Recent Pat Anticancer Drug Discov] 2016; Vol. 11 (4), pp. 461-468.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101266081 Publication Model: Print Cited Medium: Internet ISSN: 2212-3970 (Electronic) Linking ISSN: 15748928 NLM ISO Abbreviation: Recent Pat Anticancer Drug Discov Subsets: MEDLINE

مواضيع طبية MeSH: Molecular Docking Simulation* , Molecular Dynamics Simulation*, Antineoplastic Agents/*pharmacology , Enzyme Inhibitors/*pharmacology , Hydroxyurea/*pharmacology , Neoplasms/*drug therapy , Ribonucleotide Reductases/*antagonists & inhibitors, Antineoplastic Agents/chemistry ; Antineoplastic Agents/metabolism ; Binding Sites ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/metabolism ; Humans ; Hydroxyurea/chemistry ; Hydroxyurea/metabolism ; Neoplasms/enzymology ; Oxidation-Reduction ; Protein Binding ; Protein Conformation ; Ribonucleotide Reductases/chemistry ; Ribonucleotide Reductases/metabolism ; Structure-Activity Relationship

المؤلفون: Gokhale N, Jain S, Yadav M; Department of Pharmaceutical Chemistry, Suresh Gyan Vihar University, Jaipur, India-302004. niharikasubhedar@gmail.com.

المصدر: Current topics in medicinal chemistry [Curr Top Med Chem] 2015; Vol. 15 (1), pp. 37-42.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101119673 Publication Model: Print Cited Medium: Internet ISSN: 1873-4294 (Electronic) Linking ISSN: 15680266 NLM ISO Abbreviation: Curr Top Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Drug Design*, Antineoplastic Agents/*chemistry , Enzyme Inhibitors/*chemistry , Ribonucleotide Reductases/*antagonists & inhibitors , Thiosemicarbazones/*chemistry, Amino Acid Motifs ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/pharmacology ; Biological Transport ; Catalytic Domain ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/pharmacology ; High-Throughput Screening Assays ; Humans ; Hydrogen Bonding ; Hydrophobic and Hydrophilic Interactions ; Inhibitory Concentration 50 ; MCF-7 Cells ; Molecular Docking Simulation ; Protein Binding ; Ribonucleotide Reductases/chemistry ; Structure-Activity Relationship ; Thiosemicarbazones/chemical synthesis ; Thiosemicarbazones/pharmacology ; User-Computer Interface

المؤلفون: Moorthy NS; REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto, s/n, Rua do Campo Alegre, 4169-007 Porto, Portugal. hari.moorthy@fc.up.pt., Cerqueira NM, Ramos MJ, Fernandes PA

المصدر: Mini reviews in medicinal chemistry [Mini Rev Med Chem] 2013 Nov; Vol. 13 (13), pp. 1862-72.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: Netherlands NLM ID: 101094212 Publication Model: Print Cited Medium: Internet ISSN: 1875-5607 (Electronic) Linking ISSN: 13895575 NLM ISO Abbreviation: Mini Rev Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Drug Discovery/*methods , Enzyme Inhibitors/*chemistry , Enzyme Inhibitors/*pharmacology , Ribonucleotide Reductases/*antagonists & inhibitors, Animals ; Humans ; Ribonucleotide Reductases/chemistry ; Ribonucleotide Reductases/metabolism ; Structure-Activity Relationship

المؤلفون: Cerqueira NM; REQUIMTE / Faculdade de Ciências do Porto, Rua Campo Alegre, 687, 4169-007 Porto, Portugal. nscerque@fc.up.pt, Fernandes PA, Ramos MJ

المصدر: Recent patents on anti-cancer drug discovery [Recent Pat Anticancer Drug Discov] 2007 Jan; Vol. 2 (1), pp. 11-29.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101266081 Publication Model: Print Cited Medium: Print ISSN: 1574-8928 (Print) Linking ISSN: 15748928 NLM ISO Abbreviation: Recent Pat Anticancer Drug Discov Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Antineoplastic Agents/*therapeutic use , Antiviral Agents/*pharmacology , Antiviral Agents/*therapeutic use , Enzyme Inhibitors/*pharmacology , Enzyme Inhibitors/*therapeutic use , Ribonucleotide Reductases/*antagonists & inhibitors, Animals ; Gene Expression Regulation, Enzymologic/drug effects ; Humans ; Protein Conformation ; Ribonucleotide Reductases/biosynthesis ; Ribonucleotide Reductases/genetics

المؤلفون: Basu A; Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi, Jharkhand 835 215, India. abasu@bitmesra.ac.in, Sinha BN

المصدر: Current topics in medicinal chemistry [Curr Top Med Chem] 2012; Vol. 12 (24), pp. 2827-42.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101119673 Publication Model: Print Cited Medium: Internet ISSN: 1873-4294 (Electronic) Linking ISSN: 15680266 NLM ISO Abbreviation: Curr Top Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Drug Design*, Free Radical Scavengers/*chemistry , Ribonucleotide Reductases/*antagonists & inhibitors, Binding Sites ; Drug Discovery ; Free Radical Scavengers/classification ; Guanidines/chemistry ; Humans ; Hydroxamic Acids/chemistry ; Hydroxyurea/chemistry ; Molecular Docking Simulation ; Phenols/chemistry ; Protein Binding ; Protein Conformation ; Quantum Theory ; Ribonucleotide Reductases/chemistry

المؤلفون: Singh P; Department of Chemistry, Guru Nanak Dev University, Amritsar, India. palwinder_singh_2000@yahoo.com, Bhardwaj A

المصدر: Mini reviews in medicinal chemistry [Mini Rev Med Chem] 2008 Apr; Vol. 8 (4), pp. 388-98.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: Netherlands NLM ID: 101094212 Publication Model: Print Cited Medium: Print ISSN: 1389-5575 (Print) Linking ISSN: 13895575 NLM ISO Abbreviation: Mini Rev Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Topoisomerase II Inhibitors*, Antineoplastic Agents/*pharmacology , Neoplasms/*drug therapy , Neoplasms/*enzymology , Ribonucleotide Reductases/*antagonists & inhibitors , Thymidine Phosphorylase/*antagonists & inhibitors , Thymidylate Synthase/*antagonists & inhibitors, DNA Topoisomerases, Type II/metabolism ; Humans ; L-Lactate Dehydrogenase/antagonists & inhibitors ; L-Lactate Dehydrogenase/metabolism ; Ligands ; Neoplasms/pathology ; Prostaglandin-Endoperoxide Synthases/drug effects ; Prostaglandin-Endoperoxide Synthases/metabolism ; Ribonucleotide Reductases/metabolism ; Thymidine Phosphorylase/metabolism ; Thymidylate Synthase/metabolism

المؤلفون: Cerqueira NM; REQUIMTE/Faculdade de Ciências do Porto, Rua Campo Alegre, 687, 4169-007 Porto, Portugal., Pereira S, Fernandes PA, Ramos MJ

المصدر: Current medicinal chemistry [Curr Med Chem] 2005; Vol. 12 (11), pp. 1283-94.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 9440157 Publication Model: Print Cited Medium: Print ISSN: 0929-8673 (Print) Linking ISSN: 09298673 NLM ISO Abbreviation: Curr Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Enzyme Inhibitors/*pharmacology , Ribonucleotide Reductases/*antagonists & inhibitors, Animals ; Antineoplastic Agents/chemistry ; Catalysis/drug effects ; Dimerization ; Enzyme Inhibitors/chemistry ; Humans ; Ribonucleotide Reductases/metabolism ; Ribonucleotides/metabolism

المؤلفون: Liu J, Zhang K, Mai X; School of Pharmacy, Nanchang University, 461 Nanchang 330006, China. maixi123@aliyun.com., Wei J, Liao Y; School of Pharmacy, Nanchang University, 461 Nanchang 330006, China. jingzi5027@126.com., Zhong Y, Liu Y, Feng L, Liu C

المصدر: Medicinal chemistry (Shariqah (United Arab Emirates)) [Med Chem] 2016; Vol. 12 (1), pp. 37-47.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: Netherlands NLM ID: 101240303 Publication Model: Print Cited Medium: Internet ISSN: 1875-6638 (Electronic) Linking ISSN: 15734064 NLM ISO Abbreviation: Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Hydantoins/*pharmacology, Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Humans ; Hydantoins/chemical synthesis ; Hydantoins/chemistry ; Hydrogen Bonding ; K562 Cells ; Mice ; Molecular Docking Simulation ; Ribonucleotide Reductases/chemistry ; Saccharomyces cerevisiae Proteins/chemistry ; Structure-Activity Relationship

المؤلفون: Perez MA; REQUIMTE, Universidade do Porto, Portugal., Cerqueira NM, Fernandes PA, Ramos MJ

المصدر: Current medicinal chemistry [Curr Med Chem] 2010; Vol. 17 (26), pp. 2854-72.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 9440157 Publication Model: Print Cited Medium: Internet ISSN: 1875-533X (Electronic) Linking ISSN: 09298673 NLM ISO Abbreviation: Curr Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Enzyme Inhibitors/*chemistry , Enzyme Inhibitors/*pharmacology , Nucleosides/*chemistry , Nucleosides/*pharmacology , Ribonucleotide Reductases/*antagonists & inhibitors , Ribonucleotide Reductases/*chemistry, Humans ; Models, Biological