المؤلفون: Stratford AL; Laboratory for Oncogenomic Research, Department of Pediatrics, Child and Family Research Institute, University of British Columbia, Vancouver, BC V5Z 4H4, Canada., Fry CJ, Desilets C, Davies AH, Cho YY, Li Y, Dong Z, Berquin IM, Roux PP, Dunn SE

المصدر: Breast cancer research : BCR [Breast Cancer Res] 2008; Vol. 10 (6), pp. R99. Date of Electronic Publication: 2008 Nov 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100927353 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1465-542X (Electronic) Linking ISSN: 14655411 NLM ISO Abbreviation: Breast Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Breast Neoplasms/*metabolism , Neoplasms, Basal Cell/*metabolism , Ribosomal Protein S6 Kinases, 90-kDa/*metabolism , Y-Box-Binding Protein 1/*metabolism, Animals ; Benzopyrans/pharmacology ; Blotting, Western ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Cell Proliferation/drug effects ; Cells, Cultured ; Chromatin Immunoprecipitation ; Electrophoretic Mobility Shift Assay ; Embryo, Mammalian/cytology ; Embryo, Mammalian/drug effects ; Embryo, Mammalian/metabolism ; ErbB Receptors/metabolism ; Female ; Fibroblasts/cytology ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Gene Expression Regulation, Neoplastic ; Humans ; Immunoprecipitation ; Luciferases/metabolism ; MAP Kinase Signaling System ; Mice ; Monosaccharides/pharmacology ; Neoplasms, Basal Cell/genetics ; Neoplasms, Basal Cell/pathology ; Phosphorylation/drug effects ; Promoter Regions, Genetic ; Protein Kinase C-alpha/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; RNA, Small Interfering/pharmacology ; Ribosomal Protein S6 Kinases, 90-kDa/antagonists & inhibitors ; Ribosomal Protein S6 Kinases, 90-kDa/genetics ; Serine/chemistry ; Serine/metabolism ; Y-Box-Binding Protein 1/genetics

المؤلفون: Foey A; Kennedy Institute of Rheumatology Division, Imperial College School of Medicine, Hammersmith, London, W6 8LH, UK. a.foey@ic.ac.uk, Green P, Foxwell B, Feldmann M, Brennan F

المصدر: Arthritis research [Arthritis Res] 2002; Vol. 4 (1), pp. 64-70. Date of Electronic Publication: 2001 Oct 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100913255 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1465-9905 (Print) Linking ISSN: 14659905 NLM ISO Abbreviation: Arthritis Res Subsets: MEDLINE

مواضيع طبية MeSH: Arthritis, Rheumatoid/*enzymology , Interleukin-10/*biosynthesis , Macrophages/*enzymology , Phosphatidylinositol 3-Kinases/*metabolism , Ribosomal Protein S6 Kinases/*metabolism , T-Lymphocytes/*enzymology, Androstadienes/pharmacology ; Arthritis, Rheumatoid/pathology ; Cells, Cultured ; Chromones/pharmacology ; Coculture Techniques ; Cytokines/pharmacology ; Enzyme Inhibitors ; Humans ; Macrophages/drug effects ; Morpholines/pharmacology ; Phosphoinositide-3 Kinase Inhibitors ; Ribosomal Protein S6 Kinases/antagonists & inhibitors ; Signal Transduction ; Sirolimus/pharmacology ; Synovial Membrane/metabolism ; Synovial Membrane/pathology ; T-Lymphocytes/drug effects ; Wortmannin

المؤلفون: Gopinath SD; Translational Health Science and Technology Institute (THSTI), NCR Biotech Science Cluster, 3rd Milestone, Faridabad-Gurgaon Expressway, PO box #04, Faridabad, 121001, India. sgopinath@thsti.res.in.

المصدر: Skeletal muscle [Skelet Muscle] 2017 Jan 25; Vol. 7 (1), pp. 2. Date of Electronic Publication: 2017 Jan 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101561193 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-5040 (Electronic) Linking ISSN: 20445040 NLM ISO Abbreviation: Skelet Muscle Subsets: MEDLINE

مواضيع طبية MeSH: Signal Transduction*, Muscle, Skeletal/*metabolism , Muscular Atrophy/*metabolism , Receptors, Calcitriol/*metabolism , STAT3 Transcription Factor/*metabolism, Animals ; Mice ; Muscle, Skeletal/pathology ; Muscular Atrophy/genetics ; Myostatin/genetics ; Myostatin/metabolism ; Receptors, Calcitriol/genetics ; Ribosomal Protein S6/metabolism ; Ribosomal Protein S6 Kinases/metabolism ; TOR Serine-Threonine Kinases/metabolism ; Vitamin D/metabolism

المؤلفون: Zhang H, Cohen AL, Krishnakumar S, Wapnir IL, Veeriah S, Deng G, Coram MA, Piskun CM, Longacre TA, Herrler M, Frimannsson DO, Telli ML, Dirbas FM, Matin AC, Dairkee SH, Larijani B, Glinsky GV, Bild AH, Jeffrey SS

المصدر: Breast cancer research : BCR [Breast Cancer Res] 2014 Apr 07; Vol. 16 (2), pp. R36. Date of Electronic Publication: 2014 Apr 07.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100927353 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-542X (Electronic) Linking ISSN: 14655411 NLM ISO Abbreviation: Breast Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*therapeutic use , TOR Serine-Threonine Kinases/*antagonists & inhibitors , Triple Negative Breast Neoplasms/*drug therapy , Xenograft Model Antitumor Assays/*methods, Animals ; Blotting, Western ; Cell Line, Tumor ; Class I Phosphatidylinositol 3-Kinases ; Comparative Genomic Hybridization ; DNA Mutational Analysis ; Doxorubicin/therapeutic use ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Immunohistochemistry ; MCF-7 Cells ; Mice ; Mutation ; Oligonucleotide Array Sequence Analysis ; Phosphatidylinositol 3-Kinases/genetics ; Phosphorylation/drug effects ; Ribosomal Protein S6 Kinases, 70-kDa/genetics ; Ribosomal Protein S6 Kinases, 70-kDa/metabolism ; Sirolimus/analogs & derivatives ; Sirolimus/therapeutic use ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism ; Transcriptome/drug effects ; Triple Negative Breast Neoplasms/genetics ; Triple Negative Breast Neoplasms/metabolism

المؤلفون: Deb S, Do H, Byrne D, Jene N, Dobrovic A, Fox SB

مؤلفون مشاركون: kConFab Investigators

المصدر: Breast cancer research : BCR [Breast Cancer Res] 2013; Vol. 15 (4), pp. R69.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100927353 Publication Model: Print Cited Medium: Internet ISSN: 1465-542X (Electronic) Linking ISSN: 14655411 NLM ISO Abbreviation: Breast Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Genes, BRCA2* , Mutation*, Breast Neoplasms, Male/*genetics , Phosphatidylinositol 3-Kinases/*genetics, Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Adult ; Aged ; Biomarkers ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; Breast Neoplasms, Male/metabolism ; Breast Neoplasms, Male/mortality ; Breast Neoplasms, Male/pathology ; Cell Cycle Proteins ; Class I Phosphatidylinositol 3-Kinases ; Female ; Gene Expression ; Genes, BRCA1 ; Genetic Predisposition to Disease ; Germ-Line Mutation ; Heterozygote ; Humans ; Male ; Middle Aged ; Neoplasm Grading ; Phenotype ; Phosphatidylinositol 3-Kinases/metabolism ; Phosphoproteins/genetics ; Phosphoproteins/metabolism ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Ribosomal Protein S6 Kinases/genetics ; Ribosomal Protein S6 Kinases/metabolism ; Tumor Burden

SCR Disease Name: Breast Cancer, Familial Male

المؤلفون: Shrivastav A, Bruce M, Jaksic D, Bader T, Seekallu S, Penner C, Nugent Z, Watson P, Murphy L

المصدر: Breast cancer research : BCR [Breast Cancer Res] 2014 May 22; Vol. 16 (3), pp. R49. Date of Electronic Publication: 2014 May 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100927353 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-542X (Electronic) Linking ISSN: 14655411 NLM ISO Abbreviation: Breast Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Breast Neoplasms/*drug therapy , Estrogen Receptor alpha/*metabolism , Multiprotein Complexes/*metabolism , TOR Serine-Threonine Kinases/*metabolism , Tamoxifen/*therapeutic use, Antineoplastic Agents, Hormonal/therapeutic use ; Breast Neoplasms/mortality ; Cell Line, Tumor ; Disease-Free Survival ; Drug Resistance, Neoplasm/genetics ; Enzyme Activation ; Estrogens/pharmacology ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Immunohistochemistry ; MCF-7 Cells ; Mechanistic Target of Rapamycin Complex 1 ; Middle Aged ; Multiprotein Complexes/biosynthesis ; Phosphorylation ; Ribosomal Protein S6 Kinases, 70-kDa/metabolism ; TOR Serine-Threonine Kinases/biosynthesis ; Treatment Outcome

المؤلفون: Beelen K, Opdam M, Severson TM, Koornstra RH, Vincent AD, Wesseling J, Muris JJ, Berns EM, Vermorken JB, van Diest PJ, Linn SC

المصدر: Breast cancer research : BCR [Breast Cancer Res] 2014 Jan 27; Vol. 16 (1), pp. R13. Date of Electronic Publication: 2014 Jan 27.

نوع المنشور: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100927353 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-542X (Electronic) Linking ISSN: 14655411 NLM ISO Abbreviation: Breast Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Breast Neoplasms/*drug therapy , Breast Neoplasms/*genetics , Drug Resistance, Neoplasm/*genetics , Phosphatidylinositol 3-Kinases/*genetics , Tamoxifen/*therapeutic use, Aged ; Base Sequence ; Biomarkers, Tumor/genetics ; Chemotherapy, Adjuvant ; Class I Phosphatidylinositol 3-Kinases ; Disease-Free Survival ; Female ; Humans ; Mutation ; PTEN Phosphohydrolase/biosynthesis ; Phosphatidylinositol 3-Kinases/metabolism ; Phosphoinositide-3 Kinase Inhibitors ; Postmenopause ; Proto-Oncogene Proteins c-akt/antagonists & inhibitors ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Receptor, ErbB-2/biosynthesis ; Receptor, IGF Type 1/biosynthesis ; Receptors, Estrogen/metabolism ; Retrospective Studies ; Ribosomal Protein S6 Kinases, 70-kDa/genetics ; Sequence Analysis, DNA ; TOR Serine-Threonine Kinases/antagonists & inhibitors ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism ; Translational Research, Biomedical

المؤلفون: Beelen K, Opdam M, Severson TM, Koornstra RH, Vincent AD, Wesseling J, Muris JJ, Berns EM, Vermorken JB, van Diest PJ, Linn SC

المصدر: Breast cancer research : BCR [Breast Cancer Res] 2014 Jan 21; Vol. 16 (1), pp. R6. Date of Electronic Publication: 2014 Jan 21.

نوع المنشور: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100927353 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-542X (Electronic) Linking ISSN: 14655411 NLM ISO Abbreviation: Breast Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Drug Resistance, Neoplasm*, Antineoplastic Agents, Hormonal/*therapeutic use , Breast Neoplasms/*drug therapy , Ribosomal Protein S6 Kinases, 70-kDa/*metabolism , Tamoxifen/*therapeutic use, Aged ; Breast Neoplasms/genetics ; Chemotherapy, Adjuvant ; Estrogen Antagonists/therapeutic use ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Female ; Humans ; Mitogen-Activated Protein Kinases/metabolism ; Neoplasm Recurrence, Local/epidemiology ; Phosphatidylinositol 3-Kinase/metabolism ; Phosphorylation ; Postmenopause ; Proto-Oncogene Proteins c-akt/metabolism ; Retrospective Studies ; TOR Serine-Threonine Kinases/metabolism ; Treatment Outcome

المؤلفون: Karlsson E, Pérez-Tenorio G, Amin R, Bostner J, Skoog L, Fornander T, Sgroi DC, Nordenskjöld B, Hallbeck AL, Stål O

المصدر: Breast cancer research : BCR [Breast Cancer Res] 2013; Vol. 15 (5), pp. R96.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100927353 Publication Model: Print Cited Medium: Internet ISSN: 1465-542X (Electronic) Linking ISSN: 14655411 NLM ISO Abbreviation: Breast Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation, Neoplastic*, Adaptor Proteins, Signal Transducing/*genetics , Breast Neoplasms/*genetics , Breast Neoplasms/*metabolism , Phosphoproteins/*genetics , Ribosomal Protein S6 Kinases, 70-kDa/*genetics , TOR Serine-Threonine Kinases/*metabolism, Antineoplastic Agents, Hormonal ; Breast Neoplasms/drug therapy ; Breast Neoplasms/mortality ; Cell Cycle Proteins ; Drug Resistance, Neoplasm ; Female ; Gene Amplification ; Humans ; Patient Outcome Assessment ; Prognosis ; RNA, Messenger/genetics ; Recurrence ; Retrospective Studies ; Tamoxifen/therapeutic use

المؤلفون: Nagalingam A; Department of Oncology, Johns Hopkins University School of Medicine and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore MD 21231, USA., Arbiser JL, Bonner MY, Saxena NK, Sharma D

المصدر: Breast cancer research : BCR [Breast Cancer Res] 2012 Feb 21; Vol. 14 (1), pp. R35. Date of Electronic Publication: 2012 Feb 21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100927353 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-542X (Electronic) Linking ISSN: 14655411 NLM ISO Abbreviation: Breast Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: AMP-Activated Protein Kinases/*metabolism , Antineoplastic Agents/*pharmacology , Biphenyl Compounds/*pharmacology , Breast Neoplasms/*drug therapy , Lignans/*pharmacology , Protein Serine-Threonine Kinases/*metabolism, AMP-Activated Protein Kinase Kinases ; AMP-Activated Protein Kinases/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Antineoplastic Agents/therapeutic use ; Biphenyl Compounds/therapeutic use ; Breast Neoplasms/pathology ; Cell Cycle Proteins ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Transformation, Neoplastic/drug effects ; Enzyme Activation/drug effects ; Female ; Gene Expression ; Humans ; Lignans/therapeutic use ; Mice ; Mice, Nude ; Neoplasm Invasiveness ; Phosphoproteins/metabolism ; Phosphorylation ; Protein Processing, Post-Translational/drug effects ; Protein Serine-Threonine Kinases/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Ribosomal Protein S6 Kinases/metabolism ; Spheroids, Cellular/drug effects ; Spheroids, Cellular/physiology ; TOR Serine-Threonine Kinases/metabolism ; Tumor Burden/drug effects ; Xenograft Model Antitumor Assays