المؤلفون: Thushan I. de Silva, Guihai Liu, Benjamin B. Lindsey, Danning Dong, Shona C. Moore, Nienyun Sharon Hsu, Dhruv Shah, Dannielle Wellington, Alexander J. Mentzer, Adrienn Angyal, Rebecca Brown, Matthew D. Parker, Zixi Ying, Xuan Yao, Lance Turtle, Susanna Dunachie, Mala K. Maini, Graham Ogg, Julian C. Knight, Yanchun Peng, Sarah L. Rowland-Jones, Tao Dong, David M. Aanensen, Khalil Abudahab, Helen Adams, Alexander Adams, Safiah Afifi, Dinesh Aggarwal, Shazaad S.Y. Ahmad, Louise Aigrain, Adela Alcolea-Medina, Nabil-Fareed Alikhan, Elias Allara, Roberto Amato, Tara Annett, Stephen Aplin, Cristina V. Ariani, Hibo Asad, Amy Ash, Paula Ashfield, Fiona Ashford, Laura Atkinson, Stephen W. Attwood, Cressida Auckland, Alp Aydin, David J. Baker, Paul Baker, Carlos E. Balcazar, Jonathan Ball, Jeffrey C. Barrett, Magdalena Barrow, Edward Barton, Matthew Bashton, Andrew R. Bassett, Rahul Batra, Chris Baxter, Nadua Bayzid, Charlotte Beaver, Angela H. Beckett, Shaun M. Beckwith, Luke Bedford, Robert Beer, Andrew Beggs, Katherine L. Bellis, Louise Berry, Beatrice Bertolusso, Angus Best, Emma Betteridge, David Bibby, Kelly Bicknell, Debbie Binns, Alec Birchley, Paul W. Bird, Chloe Bishop, Rachel Blacow, Victoria Blakey, Beth Blane, Frances Bolt, James Bonfield, Stephen Bonner, David Bonsall, Tim Boswell, Andrew Bosworth, Yann Bourgeois, Olivia Boyd, Declan T. Bradley, Cassie Breen, Catherine Bresner, Judith Breuer, Stephen Bridgett, Iraad F. Bronner, Ellena Brooks, Alice Broos, Julianne R. Brown, Giselda Bucca, Sarah L. Buchan, David Buck, Matthew Bull, Phillipa J. Burns, Shirelle Burton-Fanning, Timothy Byaruhanga, Matthew Byott, Sharon Campbell, Alessandro M. Carabelli, James S. Cargill, Matthew Carlile, Silvia F. Carvalho, Anna Casey, Anibolina Castigador, Jana Catalan, Vicki Chalker, Nicola J. Chaloner, Meera Chand, Joseph G. Chappell, Themoula Charalampous, Wendy Chatterton, Yasmin Chaudhry, Carol M. Churcher, Gemma Clark, Phillip Clarke, Benjamin J. Cogger, Kevin Cole, Jennifer Collins, Rachel Colquhoun, Thomas R. Connor, Kate F. Cook, Jason Coombes, Sally Corden, Claire Cormie, Nicholas Cortes, Marius Cotic, Seb Cotton, Simon Cottrell, Lindsay Coupland, MacGregor Cox, Alison Cox, Noel Craine, Liam Crawford, Aidan Cross, Matthew R. Crown, Dorian Crudgington, Nicola Cumley, Tanya Curran, Martin D. Curran, Ana da Silva Filipe, Gavin Dabrera, Alistair C. Darby, Rose K. Davidson, Alisha Davies, Robert M. Davies, Thomas Davis, Daniela de Angelis, Elen De Lacy, Leonardo de Oliveira Martins, Johnny Debebe, Rebecca Denton-Smith, Samir Dervisevic, Rebecca Dewar, Jayasree Dey, Joana Dias, Donald Dobie, Matthew J. Dorman, Fatima Downing, Megan Driscoll, Louis du Plessis, Nichola Duckworth, Jillian Durham, Kirstine Eastick, Lisa J. Easton, Richard Eccles, Jonathan Edgeworth, Sue Edwards, Kate El Bouzidi, Sahar Eldirdiri, Nicholas Ellaby, Scott Elliott, Gary Eltringham, Leah Ensell, Michelle J. Erkiert, Marina Escalera Zamudio, Sarah Essex, Johnathan M. Evans, Cariad Evans, William Everson, Derek J. Fairley, Karlie Fallon, Arezou Fanaie, Ben W. Farr, Christopher Fearn, Theresa Feltwell, Lynne Ferguson, Laia Fina, Flavia Flaviani, Vicki M. Fleming, Sally Forrest, Ebenezer Foster-Nyarko, Benjamin H. Foulkes, Luke Foulser, Mireille Fragakis, Dan Frampton, Sarah Francois, Christophe Fraser, Timothy M. Freeman, Helen Fryer, Marc Fuchs, William Fuller, Kavitha Gajee, Katerina Galai, Abbie Gallagher, Eileen Gallagher, Michael D. Gallagher, Marta Gallis, Amy Gaskin, Bree Gatica-Wilcox, Lily Geidelberg, Matthew Gemmell, Iliana Georgana, Ryan P. George, Laura Gifford, Lauren Gilbert, Sophia T. Girgis, Sharon Glaysher, Emily J. Goldstein, Tanya Golubchik, Andrea N. Gomes, Sónia Gonçalves, Ian G. Goodfellow, Scott Goodwin, Salman Goudarzi, Marina Gourtovaia, Clive Graham, Lee Graham, Paul R. Grant, Luke R. Green, Angie Green, Jane Greenaway, Richard Gregory, Martyn Guest, Rory N. Gunson, Ravi K. Gupta, Bernardo Gutierrez, Sam T. Haldenby, William L. Hamilton, Samantha E. Hansford, Tanzina Haque, Kathryn A. Harris, Ian Harrison, Ewan M. Harrison, Jennifer Hart, John A. Hartley, William T. Harvey, Matthew Harvey, Mohammed O. Hassan-Ibrahim, Judith Heaney, Thomas Helmer, John H. Henderson, Andrew R. Hesketh, Jessica Hey, David Heyburn, Ellen E. Higginson, Verity Hill, Jack D. Hill, Rachel A. Hilson, Ember Hilvers, Matthew T.G. Holden, Amy Hollis, Christopher W. Holmes, Nadine Holmes, Alison H. Holmes, Richard Hopes, Hailey R. Hornsby, Myra Hosmillo, Catherine Houlihan, Hannah C. Howson-Wells, Jonathan Hubb, Hannah Huckson, Warwick Hughes, Joseph Hughes, Margaret Hughes, Stephanie Hutchings, Giles Idle, Chris J. Illingworth, Robert Impey, Dianne Irish-Tavares, Miren Iturriza-Gomara, Rhys Izuagbe, Chris Jackson, Ben Jackson, Leigh M. Jackson, Kathryn A. Jackson, David K. Jackson, Aminu S. Jahun, Victoria James, Keith James, Christopher Jeanes, Aaron R. Jeffries, Sarah Jeremiah, Andrew Jermy, Michaela John, Rob Johnson, Kate Johnson, Ian Johnston, Owen Jones, Sophie Jones, Hannah Jones, Christopher R. Jones, Neil Jones, Amelia Joseph, Sarah Judges, Gemma L. Kay, Sally Kay, Jon-Paul Keatley, Alexander J. Keeley, Anita Kenyon, Leanne M. Kermack, Manjinder Khakh, Stephen P. Kidd, Maimuna Kimuli, Stuart Kirk, Christine Kitchen, Katie Kitchman, Bridget A. Knight, Cherian Koshy, Moritz U.G. Kraemer, Sara Kumziene-Summerhayes, Dominic Kwiatkowski, Angie Lackenby, Kenneth G. Laing, Temi Lampejo, Cordelia F. Langford, Deborah Lavin, Andrew I. Lawton, Jack Lee, David Lee, Stefanie V. Lensing, Steven Leonard, Lisa J. Levett, Thanh Le-Viet, Jonathan Lewis, Kevin Lewis, Jennifier Liddle, Steven Liggett, Patrick J. Lillie, Michelle M. Lister, Rich Livett, Stephanie Lo, Nicholas J. Loman, Matthew W. Loose, Stavroula F. Louka, Katie F. Loveson, Sarah Lowdon, Hannah Lowe, Helen L. Lowe, Anita O. Lucaci, Catherine Ludden, Jessica Lynch, Ronan A. Lyons, Katrina Lythgoe, Nicholas W. Machin, George MacIntyre-Cockett, Andrew Mack, Ben Macklin, Alasdair Maclean, Emily Macnaughton, Pinglawathee Madona, Mailis Maes, Laurentiu Maftei, Adhyana I.K. Mahanama, Tabitha W. Mahungu, Daniel Mair, Joshua Maksimovic, Cassandra S. Malone, Daniel Maloney, Nikos Manesis, Robin Manley, Anna Mantzouratou, Angela Marchbank, Arun Mariappan, Inigo Martincorena, Rocio T. Martinez Nunez, Alison E. Mather, Patrick Maxwell, Megan Mayhew, Tamyo Mbisa, Clare M. McCann, Shane A. McCarthy, Kathryn McCluggage, Patrick C. McClure, J.T. McCrone, Martin P. McHugh, James P. McKenna, Caoimhe McKerr, Georgina M. McManus, Claire L. McMurray, Claire McMurray, Alan McNally, Lizzie Meadows, Nathan Medd, Oliver Megram, Mirko Menegazzo, Ian Merrick, Stephen L. Michell, Michelle L. Michelsen, Mariyam Mirfenderesky, Jeremy Mirza, Julia Miskelly, Emma Moles-Garcia, Robin J. Moll, Zoltan Molnar, Irene M. Monahan, Matteo Mondani, Siddharth Mookerjee, Christopher Moore, Jonathan Moore, Nathan Moore, Catherine Moore, Helen Morcrette, Sian Morgan, Mari Morgan, Matilde Mori, Arthur Morriss, Samuel Moses, Craig Mower, Peter Muir, Afrida Mukaddas, Florence Munemo, Robert Munn, Abigail Murray, Leanne J. Murray, Darren R. Murray, Manasa Mutingwende, Richard Myers, Eleni Nastouli, Gaia Nebbia, Andrew Nelson, Charlotte Nelson, Sam Nicholls, Jenna Nichols, Roberto Nicodemi, Kyriaki Nomikou, Justin O’Grady, Sarah O'Brien, Mina Odedra, Natasha Ohemeng-Kumi, Karen Oliver, Richard J. Orton, Husam Osman, null xeine O'Toole, Nicole Pacchiarini, Debra Padgett, Andrew J. Page, Emily J. Park, Naomi R. Park, Surendra Parmar, David G. Partridge, David Pascall, Amita Patel, Bindi Patel, Steve Paterson, Brendan A.I. Payne, Sharon J. Peacock, Clare Pearson, Emanuela Pelosi, Benita Percival, Jon Perkins, Malorie Perry, Malte L. Pinckert, Steven Platt, Olga Podplomyk, Manoj Pohare, Marcus Pond, Cassie F. Pope, Radoslaw Poplawski, Jessica Powell, Jennifer Poyner, Liam Prestwood, Anna Price, James R. Price, Jacqui A. Prieto, David T. Pritchard, Sophie J. Prosolek, Georgia Pugh, Monika Pusok, Oliver G. Pybus, Hannah M. Pymont, Michael A. Quail, Joshua Quick, Clara Radulescu, Jayna Raghwani, Manon Ragonnet-Cronin, Lucille Rainbow, Diana Rajan, Shavanthi Rajatileka, Newara A. Ramadan, Andrew Rambaut, John Ramble, Paul A. Randell, Paul Randell, Liz Ratcliffe, Veena Raviprakash, Mohammad Raza, Nicholas M. Redshaw, Sara Rey, Nicola Reynolds, Alex Richter, David L. Robertson, Esther Robinson, Samuel C. Robson, Fiona Rogan, Stefan Rooke, Will Rowe, Sunando Roy, Steven Rudder, Chris Ruis, Steven Rushton, Felicity Ryan, Kordo Saeed, Buddhini Samaraweera, Christine M. Sambles, Roy Sanderson, Theo Sanderson, Fei Sang, Thea Sass, Emily Scher, Garren Scott, Carol Scott, Jasveen Sehmi, Sharif Shaaban, Divya Shah, Jessica Shaw, Ekaterina Shelest, James G. Shepherd, Liz A. Sheridan, Nicola Sheriff, Lesley Shirley, John Sillitoe, Siona Silviera, David A. Simpson, Aditi Singh, Dawn Singleton, Timofey Skvortsov, Tim J. Sloan, Graciela Sluga, Ken Smith, Kim S. Smith, Perminder Smith, Darren L. Smith, Louise Smith, Colin P. Smith, Nikki Smith, Katherine L. Smollett, Luke B. Snell, Thomas Somassa, Joel Southgate, Karla Spellman, Michael H. Spencer Chapman, Lewis G. Spurgin, Moira J. Spyer, Rachael Stanley, William Stanley, Thomas D. Stanton, Igor Starinskij, Joanne Stockton, Susanne Stonehouse, Nathaniel Storey, David J. Studholme, Malur Sudhanva, Emma Swindells, Yusri Taha, Ngee Keong Tan, Julian W. Tang, Miao Tang, Ben E.W. Taylor, Joshua F. Taylor, Sarah Taylor, Ben Temperton, Kate E. Templeton, Claire Thomas, Laura Thomson, Emma C. Thomson, Alicia Thornton, Scott A.J. Thurston, John A. Todd, Rachael Tomb, Lily Tong, Gerry Tonkin-Hill, M. Estee Torok, Jaime M. Tovar-Corona, Amy Trebes, Alexander J. Trotter, Ioulia Tsatsani, Robyn Turnbull, Katherine A. Twohig, Helen Umpleby, Anthony P. Underwood, Edith E. Vamos, Tetyana I. Vasylyeva, Sreenu Vattipally, Gabrielle Vernet, Barry B. Vipond, Erik M. Volz, Sarah Walsh, Dennis Wang, Ben Warne, Joanna Warwick-Dugdale, Elizabeth Wastnedge, Joanne Watkins, Louisa K. Watson, Sheila Waugh, Hermione J. Webster, Danni Weldon, Elaine Westwick, Thomas Whalley, Helen Wheeler, Mark Whitehead, Max Whiteley, Andrew Whitwham, Claudia Wierzbicki, Nicholas J. Willford, Lesley-Anne Williams, Rebecca Williams, Cheryl Williams, Chris Williams, Charlotte A. Williams, Rachel J. Williams, Thomas Williams, Catryn Williams, Kathleen A. Williamson, Eleri Wilson-Davies, Eric Witele, Karen T. Withell, Adam A. Witney, Paige Wolverson, Nick Wong, Trudy Workman, Victoria Wright, Derek W. Wright, Tim Wyatt, Sarah Wyllie, Li Xu-McCrae, Mehmet Yavus, Geraldine Yaze, Corin A. Yeats, Gonzalo Yebra, Wen C. Yew, Gregory R. Young, Jamie Young, Alex E. Zarebski, Peijun Zhang, J. Kenneth Baillie, Malcolm G. Semple, Peter J.M. Openshaw, Gail Carson, Beatrice Alex, Petros Andrikopoulos, Benjamin Bach, Wendy S. Barclay, Debby Bogaert, Kanta Chechi, Graham S. Cooke, Annemarie B. Docherty, Gonçalo dos Santos Correia, Marc-Emmanuel Dumas, Jake Dunning, Tom Fletcher, Christopher A. Green, William Greenhalf, Julian L. Griffin, Rishi K. Gupta, Ewen M. Harrison, Julian A. Hiscox, Antonia Ying Wai Ho, Peter W. Horby, Samreen Ijaz, Saye Khoo, Paul Klenerman, Andrew Law, Matthew R. Lewis, Sonia Liggi, Wei Shen Lim, Lynn Maslen, Laura Merson, Alison M. Meynert, Mahdad Noursadeghi, Michael Olanipekun, Anthonia Osagie, Massimo Palmarini, Carlo Palmieri, William A. Paxton, Georgios Pollakis, Nicholas Price, Clark D. Russell, Vanessa Sancho-Shimizu, Caroline J. Sands, Janet T. Scott, Louise Sigfrid, Tom Solomon, Shiranee Sriskandan, David Stuart, Charlotte Summers, Olivia V. Swann, Zoltan Takats, Panteleimon Takis, Richard S. Tedder, A.A. Roger Thompson, Ryan S. Thwaites, Maria Zambon, Hayley Hardwick, Chloe Donohue, Fiona Griffiths, Wilna Oosthuyzen, Cara Donegan, Rebecca G. Spencer, Jo Dalton, Michelle Girvan, Egle Saviciute, Stephanie Roberts, Janet Harrison, Laura Marsh, Marie Connor, Sophie Halpin, Clare Jackson, Carrol Gamble, Daniel Plotkin, James Lee, Gary Leeming, Murray Wham, Sara Clohisey, Ross Hendry, James Scott-Brown, Victoria Shaw, Sarah E. McDonald, Seán Keating, Katie A. Ahmed, Jane A. Armstrong, Milton Ashworth, Innocent G. Asiimwe, Siddharth Bakshi, Samantha L. Barlow, Laura Booth, Benjamin Brennan, Katie Bullock, Benjamin W.A. Catterall, Jordan J. Clark, Emily A. Clarke, Sarah Cole, Louise Cooper, Helen Cox, Christopher Davis, Oslem Dincarslan, Chris Dunn, Philip Dyer, Angela Elliott, Anthony Evans, Lorna Finch, Lewis W.S. Fisher, Terry Foster, Isabel Garcia-Dorival, Philip Gunning, Catherine Hartley, Rebecca L. Jensen, Christopher B. Jones, Trevor R. Jones, Shadia Khandaker, Katharine King, Robyn T. Kiy, Chrysa Koukorava, Annette Lake, Suzannah Lant, Diane Latawiec, Lara Lavelle-Langham, Daniella Lefteri, Lauren Lett, Lucia A. Livoti, Maria Mancini, Sarah McDonald, Laurence McEvoy, John McLauchlan, Soeren Metelmann, Nahida S. Miah, Joanna Middleton, Joyce Mitchell, Ellen G. Murphy, Rebekah Penrice-Randal, Jack Pilgrim, Tessa Prince, Will Reynolds, P. Matthew Ridley, Debby Sales, Victoria E. Shaw, Rebecca K. Shears, Benjamin Small, Krishanthi S. Subramaniam, Agnieska Szemiel, Aislynn Taggart, Jolanta Tanianis-Hughes, Jordan Thomas, Erwan Trochu, Libby van Tonder, Eve Wilcock, J. Eunice Zhang, Lisa Flaherty, Nicole Maziere, Emily Cass, Alejandra Doce Carracedo, Nicola Carlucci, Anthony Holmes, Hannah Massey, Lee Murphy, Nicola Wrobel, Sarah McCafferty, Kirstie Morrice, Alan MacLean, Kayode Adeniji, Daniel Agranoff, Ken Agwuh, Dhiraj Ail, Erin L. Aldera, Ana Alegria, Sam Allen, Brian Angus, Abdul Ashish, Dougal Atkinson, Shahedal Bari, Gavin Barlow, Stella Barnass, Nicholas Barrett, Christopher Bassford, Sneha Basude, David Baxter, Michael Beadsworth, Jolanta Bernatoniene, John Berridge, Colin Berry, Nicola Best, Pieter Bothma, David Chadwick, Robin Brittain-Long, Naomi Bulteel, Tom Burden, Andrew Burtenshaw, Vikki Caruth, Duncan Chambler, Nigel Chee, Jenny Child, Srikanth Chukkambotla, Tom Clark, Paul Collini, Catherine Cosgrove, Jason Cupitt, Maria-Teresa Cutino-Moguel, Paul Dark, Chris Dawson, Phil Donnison, Sam Douthwaite, Andrew Drummond, Ingrid DuRand, Ahilanadan Dushianthan, Tristan Dyer, Chi Eziefula, Chrisopher Fegan, Adam Finn, Duncan Fullerton, Sanjeev Garg, Atul Garg, Effrossyni Gkrania-Klotsas, Jo Godden, Arthur Goldsmith, Elaine Hardy, Stuart Hartshorn, Daniel Harvey, Peter Havalda, Daniel B. Hawcutt, Maria Hobrok, Luke Hodgson, Anil Hormis, Michael Jacobs, Susan Jain, Paul Jennings, Agilan Kaliappan, Vidya Kasipandian, Stephen Kegg, Michael Kelsey, Jason Kendall, Caroline Kerrison, Ian Kerslake, Oliver Koch, Gouri Koduri, George Koshy, Shondipon Laha, Steven Laird, Susan Larkin, Tamas Leiner, Patrick Lillie, James Limb, Vanessa Linnett, Jeff Little, Mark Lyttle, Michael MacMahon, Emily MacNaughton, Ravish Mankregod, Huw Masson, Elijah Matovu, Katherine McCullough, Ruth McEwen, Manjula Meda, Gary Mills, Jane Minton, Kavya Mohandas, Quen Mok, James Moon, Elinoor Moore, Patrick Morgan, Craig Morris, Katherine Mortimore, Mbiye Mpenge, Rohinton Mulla, Michael Murphy, Megan Nagel, Thapas Nagarajan, Mark Nelson, Lillian Norris, Matthew K. O'Shea, Igor Otahal, Marlies Ostermann, Mark Pais, Selva Panchatsharam, Danai Papakonstantinou, Hassan Paraiso, Brij Patel, Natalie Pattison, Justin Pepperell, Mark Peters, Mandeep Phull, Stefania Pintus, Jagtur Singh Pooni, Tim Planche, Frank Post, David Price, Rachel Prout, Nikolas Rae, Henrik Reschreiter, Tim Reynolds, Neil Richardson, Mark Roberts, Devender Roberts, Alistair Rose, Guy Rousseau, Bobby Ruge, Brendan Ryan, Taranprit Saluja, Matthias L. Schmid, Aarti Shah, Prad Shanmuga, Anil Sharma, Anna Shawcross, Jeremy Sizer, Manu Shankar-Hari, Richard Smith, Catherine Snelson, Nick Spittle, Nikki Staines, Tom Stambach, Richard Stewart, Pradeep Subudhi, Tamas Szakmany, Kate Tatham, Jo Thomas, Chris Thompson, Robert Thompson, Ascanio Tridente, Darell Tupper-Carey, Mary Twagira, Nick Vallotton, Rama Vancheeswaran, Lisa Vincent-Smith, Shico Visuvanathan, Alan Vuylsteke, Sam Waddy, Rachel Wake, Andrew Walden, Ingeborg Welters, Tony Whitehouse, Paul Whittaker, Ashley Whittington, Padmasayee Papineni, Meme Wijesinghe, Martin Williams, Lawrence Wilson, Stephen Winchester, Martin Wiselka, Adam Wolverson, Daniel G. Wootton, Andrew Workman, Bryan Yates, Peter Young

المساهمون: UK Research and Innovation, Division of Computational and Systems Medicine, Imperial College London, London, SW7 2AZ, UK, Imperial College London - National Heart and Lung Institute, Centre National de la Recherche Scientifique (CNRS), Apollo - University of Cambridge Repository

المصدر: iScience, Vol 24, Iss 11, Pp 103353-(2021)
ISCIENCE
Investigators, ISARICC & Dark, P 2021, ' The impact of viral mutations on recognition by SARS-CoV-2 specific T cells. ', iScience, vol. 24, no. 11, 103353 . https://doi.org/10.1016/j.isci.2021.103353
iScience
iScience, Elsevier, 2021, 24 (11), pp.103353. ⟨10.1016/j.isci.2021.103353⟩
de Silva, T I, Liu, G, Lindsey, B B, Dong, D, Moore, S C, Hsu, N S, Shah, D, Wellington, D, Mentzer, A J, Angyal, A, Brown, R, Parker, M D, Ying, Z, Yao, X, Turtle, L, Dunachie, S, Maini, M K, Ogg, G, Knight, J C & Peng, Y & Rowland-Jones, S L & Dong, T 2021, ' The impact of viral mutations on recognition by SARS-CoV-2 specific T cells ', iScience, vol. 24, no. 11, 103353 . https://doi.org/10.1016/j.isci.2021.103353
COVID-19 Genomics UK (COG-UK) Consortium 2021, ' The impact of viral mutations on recognition by SARS-CoV-2 specific T cells ', iScience, vol. 24, no. 11, 103353 . https://doi.org/10.1016/j.isci.2021.103353

مصطلحات موضوعية: Molecular biology, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Science, Immunology, Biology, Epitope, Article, A900, 03 medical and health sciences, 0302 clinical medicine, Data sequences, Immune system, COVID-19 Genomics UK (COG-UK) Consortium, Virology, Cytotoxic T cell, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], Immune response, Receptor, ISARIC4C Investigators, 030304 developmental biology, 0303 health sciences, Multidisciplinary, C100, A300, C900, 3. Good health, Phylogenetics, 030220 oncology & carcinogenesis, Humoral immunity, [SDV.IMM]Life Sciences [q-bio]/Immunology, CD8

وصف الملف: application/pdf; text

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8409f7c72874ec5ba933ca4e43e86f6
http://hdl.handle.net/10044/1/93203

المؤلفون: Frank L. van de Veerdonk, Maria Venichaki, Georgios Chamilos, Jean-Paul Latgé, Dimitrios Georgopoulos, Eleni Diamantaki, Mark S. Gresnigt, Tonia Akoumianaki, Mihai G. Netea, Jamel El-Benna, Katerina Vaporidi, Kieu T. T. Le, Rémi Beau, George Samonis, Elias Drakos, Frédéric Pène, Vinod Kumar, Marina Gkountzinopulou

المساهمون: Lab Excellence Inflamex (CRI INSERM U1149 - Bichat Medical Faculty), Université Paris Diderot - Paris 7 (UPD7), Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI)

المصدر: Cell Host & Microbe
Cell Host & Microbe, 2021, 29 (8), pp.1277-1293.e6. ⟨10.1016/j.chom.2021.06.002⟩
Cell Host & Microbe, 29(8), 1277-+. CELL PRESS
Cell Host Microbe
Cell Host & Microbe, 29, 1277-1293.e6
Cell Host & Microbe, 29, 8, pp. 1277-1293.e6

مصطلحات موضوعية: MAPK/ERK pathway, JAK2 TYROSINE KINASE, Phagocytosis, lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Biology, Microbiology, Monocytes, Sepsis, 03 medical and health sciences, 0302 clinical medicine, Immune system, Virology, medicine, NADPH OXIDASE, Humans, Autocrine signalling, PHOSPHORYLATION, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, Phagosome, 0303 health sciences, Phagocytes, NADPH oxidase, IFN-GAMMA, INDUCED IMMUNOSUPPRESSION, Interleukin-6, Aspergillus fumigatus, Macrophages, Nuclear Proteins, INHIBITOR, Janus Kinase 2, medicine.disease, PHAGOSOMES, Cell biology, Cytoskeletal Proteins, MICE, INFECTIONS, biology.protein, Phosphorylation, Cytokines, [SDV.IMM]Life Sciences [q-bio]/Immunology, Parasitology, AUTOPHAGY, Microtubule-Associated Proteins, 030217 neurology & neurosurgery, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bab2223b8a2085c302b2e84b1c367963
https://research.rug.nl/en/publications/b0f34f7c-ee2e-49da-9429-eb6f9bb0cf81

المؤلفون: Bjarne Bogen, Mahesh Choolani, Dedrick Kok Hong Chan, Tony Lim Kiat Hon, Charles-Antoine Dutertre, Jerry Kok Yen Chan, Florent Ginhoux, Anis Larbi, Sandrine Henri, Svetoslav Chakarov, Citra Nurfarah Zaini Mattar, Evan W. Newell, Naomi McGovern, Sofie Van Gassen, Jinmiao Chen, Simon Tavernier, Tam John Kit Chung, Michael Poidinger, Sergio Erdal Irac, Dorine Sichien, Hervé Luche, Ivy Low, Hermi Sumatoh, Sofie De Prijck, Gillian Low, Ker-Kan Tan, Bart N. Lambrecht, Even Fossum, Martin Guilliams, Yvan Saeys, Bernard Malissen, Charlotte L. Scott

المساهمون: Pulmonary Medicine, McGovern, Naomi [0000-0001-5200-2698], Apollo - University of Cambridge Repository, Department of Biomedical Molecular Biology [Ghent], Universiteit Gent = Ghent University (UGENT), Centre d'Immunologie de Marseille - Luminy (CIML), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Unit of Immunoregulation and Mucosal Immunology [Ghent, Belgium], VIB Inflammation Research Center [Ghent, Belgium], Program in Emerging Infectious Disease, Duke-NUS Medical School [Singapore], Singapore Immunology Network (SIgN), Biomedical Sciences Institute (BMSI), Department of Information Technology [Gent], Data Mining and Modeling for Biomedicine [Ghent, Belgium], Department of Internal Medicine [Ghent, Belgium], Experimental Fetal Medicine Group [Singapore], National University of Singapore (NUS)-Yong Loo Lin School of Medicine [Singapore], Department of Surgery [Singapore], Department of Pathology [Singapour], National University of Singapore (NUS), K.G. Jebsen Centre for Influenza Vaccine Research [Oslo, Norway], University of Oslo (UiO)-Oslo University Hospital [Oslo], Center for Immune Regulation [Oslo] (CIR), Faculty of Medicine [Oslo], University of Oslo (UiO)-University of Oslo (UiO)-Rigshospitalet [Copenhagen], Copenhagen University Hospital-Copenhagen University Hospital, Department of Reproductive Medicine [Singapore], KK Women's and Children's Hospital [Singapore], Cancer and Stem Cell Biology Program [Singapore], Centre d'Immunophénomique (CIPHE), Department of Pulmonary Medicine [Rotterdam, The Netherlands], Erasmus University Medical Center [Rotterdam] (Erasmus MC), Universiteit Gent = Ghent University [Belgium] (UGENT), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU), Universiteit Gent, HENRI, Sandrine

المصدر: Immunity, 45(3), 669-684. Cell Press
Immunity
Immunity, 2016, 45, pp.669-684. ⟨10.1016/j.immuni.2016.08.015⟩
Immunity, Elsevier, 2016, 45, pp.669-684. ⟨10.1016/j.immuni.2016.08.015⟩
IMMUNITY

مصطلحات موضوعية: EXPRESSION, 0301 basic medicine, Resource, STEADY-STATE, HOMEOSTASIS, BLOOD, [SDV.IMM] Life Sciences [q-bio]/Immunology, BONE-MARROW, Cellular differentiation, Immunology, Inflammation, Computational biology, Biology, Macaque, Flow cytometry, 03 medical and health sciences, Mice, 0302 clinical medicine, biology.animal, medicine, Immunology and Allergy, Macrophage, Animals, Humans, Mass cytometry, MACROPHAGES, SIGNALING CONTROLS, LYMPH-NODES, medicine.diagnostic_test, Biology and Life Sciences, hemic and immune systems, Cell Differentiation, Dendritic Cells, Flow Cytometry, CLONOGENIC PROGENITOR, Mice, Inbred C57BL, Protein Transport, 030104 developmental biology, Infectious Diseases, [SDV.IMM]Life Sciences [q-bio]/Immunology, Macaca, medicine.symptom, Conventional Dendritic Cell, Function (biology), RESPONSES, 030215 immunology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c9aea8398c0f153bc3f29b3a580d5eb
https://pure.eur.nl/en/publications/d16200db-bbe4-48c9-9f16-cfe355704c51

المؤلفون: Casper G. Schalkwijk, Leonie F. A. Huitema, Lhousseine Touqui, Marion J.J. Gijbels, Kerry-Anne Rye, Shahla Abdollahi-Roodsaz, Marjo M. P. C. Donners, Emiel P. C. van der Vorst, Kosta Theodorou, Ine M. J. Wolfs, Debby P.Y. Koonen, Christina A. Bursill, Menno P.J. de Winther, Marten A. Hoeksema, Michael Leitges, Pieter Goossens, Jogchum Plat, Marijke J.E. Kuijpers, Sander W. Tas, Toby Lawrence, Taghi Aliyev, Erik A.L. Biessen, Yongzheng Wu, Chih Chieh Wang, Miranda Van Eck, Kimberly R. McDaniels

المساهمون: Biologie cellulaire de l'Infection microbienne - Cellular Biology of Microbial Infection, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Centre d'Immunologie de Marseille - Luminy (CIML), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Laboratory for Metabolism and Vascular Medicine, Academic Hospital Maastricht, Department of rheumatology, Radboud University [Nijmegen], Biotechnology center of Oslo, Faculty of Medicine [Oslo], University of Oslo (UiO)-University of Oslo (UiO)-Rigshospitalet [Copenhagen], Copenhagen University Hospital-Copenhagen University Hospital, Human Biology, Division of Biopharmaceutics, Universiteit Leiden, Heart Research Institute, Institut Pasteur [Paris] (IP), Mucoviscidose et bronchopathies chroniques : biopathologie et phénotypes cliniques (EA 2511), Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Descartes - Paris 5 (UPD5), Biologie cellulaire de l'Infection microbienne, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU), Radboud university [Nijmegen], Universiteit Leiden [Leiden], Institut Pasteur [Paris], CHU Cochin [AP-HP]-Université Paris Descartes - Paris 5 (UPD5), Promovendi CD, Pathologie, RS: CARIM - R3.06 - The vulnerable plaque: makers and markers, Ondersteunend personeel CD, Biochemie, Moleculaire Genetica, RS: CARIM - R3.01 - Vascular complications of diabetes and the metabolic syndrome, Interne Geneeskunde, RS: NUTRIM - R1 - Obesity, diabetes and cardiovascular health, RS: NUTRIM - HB/BW section B, RS: NUTRIM - R1 - Metabolic Syndrome, Center for Liver, Digestive and Metabolic Diseases (CLDM), Cardiovascular Centre (CVC), Graduate School, Medical Biochemistry, AII - Inflammatory diseases, ACS - Amsterdam Cardiovascular Sciences, Clinical Immunology and Rheumatology, AII - Amsterdam institute for Infection and Immunity, ACS - Atherosclerosis & ischemic syndromes

المصدر: Cell Metabolism
Cell Metabolism, 2017, 25 (1), pp.197-207. ⟨10.1016/j.cmet.2016.10.013⟩
Cell Metabolism, Elsevier, 2017, 25 (1), pp.197-207. ⟨10.1016/j.cmet.2016.10.013⟩
Cell Metabolism, 25(1), 197-207. Cell Press
Cell Metabolism, 25, 197-207
Cell Metabolism, 25, 1, pp. 197-207
Cell metabolism, 25(1), 197-207. CELL PRESS
Cell metabolism, 25(1), 197-207. Cell Press

مصطلحات موضوعية: 0301 basic medicine, Physiology, NF-KAPPA-B, 030204 cardiovascular system & hematology, Mice, chemistry.chemical_compound, 0302 clinical medicine, Macrophage, Receptor, Respiratory Tract Infections, Lipid raft, Cells, Cultured, Protein Kinase C, Toll-Like Receptors, NF-kappa B, 3. Good health, Cell biology, RECEPTORS, Cholesterol, STAT1 Transcription Factor, [SDV.IMM]Life Sciences [q-bio]/Immunology, lipids (amino acids, peptides, and proteins), medicine.symptom, Lipoproteins, HDL, Inflammatory diseases Radboud Institute for Molecular Life Sciences [Radboudumc 5], Signal Transduction, EXPRESSION, medicine.medical_specialty, Inflammation, Biology, SUPPRESS, Models, Biological, 03 medical and health sciences, Membrane Microdomains, Immune system, In vivo, Internal medicine, medicine, Animals, Humans, Molecular Biology, Innate immune system, Base Sequence, Macrophages, Biological Transport, NF-κB, Cell Biology, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, chemistry, ATHEROSCLEROSIS, CELLS, Interferon Regulatory Factor-1, HDLS

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::891afe6c9368606d883f4f5ade7ebb9b
https://doi.org/10.1016/j.cmet.2016.10.013

المؤلفون: Débora M. Portilho, Juliette Fernandez, Mathieu Ringeard, Anthony K. Machado, Aude Boulay, Martha Mayer, Michaela Müller-Trutwin, Anne-Sophie Beignon, Frank Kirchhoff, Sébastien Nisole, Nathalie J. Arhel

المساهمون: Génétique et Ecologie des Virus, Génétique des Virus et Pathogénèse des Maladies Virales, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Diderot - Paris 7 (UPD7), Virologie moléculaire et Vectorologie, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Universität Ulm - Ulm University [Ulm, Allemagne], HIV, Inflammation et persistance, Institut Pasteur [Paris], Immunologie des Maladies Virales et Autoimmunes (IMVA - U1184), Université Paris-Sud - Paris 11 (UP11)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Toxicité environnementale, cibles thérapeutiques, signalisation cellulaire (T3S - UMR_S 1124), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université Paris Descartes - Paris 5 (UPD5), This work was supported by grants from the Agence Nationale de Recherches sur le SIDA et les hépatites virales (ANRS), the ATIP-Avenir program (INSERM), the Deutsche Forschungsgemeinschaft (DFG), European FP7 'HIT HIDDEN HIV' (305762), a DFG Leibniz award, and an Advanced ERC Investigator grant (to F.K.)., For veterinary support, NHP welfare, and biological specimens sampling, we thank Nathalie Dereuddre-Bosquet and Céline Gommet (CEA Fontenay-aux-Roses) for RM and CM, Thierry Petit (Zoo de la Palmyre, Les Mathes) for PTM, and Anne-Sophie Liovat for AGM. We thank Paul Bieniasz (Aaron Diamond AIDS Research Center) for the rabbit TRIM5α antibody, Nicolas Manel (Institut Curie) for the cGAS shRNA construct, Cyril Pantoli for graphic design, and Ron Hay (University of Dundee) and Allan Hance (Hôpital Saint-Louis) for helpful discussions. Protein diagrams were prepared using Illustrator for Biological Sequences. Microscopy experiments were performed at the Imagopole (Institut Pasteur) and the technology platform of Hôpital Saint-Louis., European Project: 305762,HEALTH,FP7-HEALTH-2012-INNOVATION-1,HIT HIDDEN HIV(2012), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), HIV, Inflammation et persistance - HIV, Inflammation and Persistence, Institut Pasteur [Paris] (IP), Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris], Université Paris-Sud - Paris 11 (UP11)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Université Paris Descartes - Paris 5 (UPD5)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: Cell Reports
Cell Reports, Elsevier Inc, 2016, 14 (2), pp.355-369. ⟨10.1016/j.celrep.2015.12.039⟩
Cell Reports, 2016, 14 (2), pp.355-369. ⟨10.1016/j.celrep.2015.12.039⟩
Cell Reports, Vol 14, Iss 2, Pp 355-369 (2016)

مصطلحات موضوعية: MESH: Humans, MESH: Dendritic Cells, MESH: Sumoylation, [SDV]Life Sciences [q-bio], Ubiquitin-Protein Ligases, Proteins, Sumoylation, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Dendritic Cells, [SDV.IMM.II]Life Sciences [q-bio]/Immunology/Innate immunity, Macaca mulatta, Article, MESH: Macaca mulatta, lcsh:Biology (General), [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, [SDV.IMM]Life Sciences [q-bio]/Immunology, Animals, Humans, MESH: Animals, MESH: Proteins, lcsh:QH301-705.5

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0dc9bbaef651a732fff6253e4688f9dc
http://europepmc.org/articles/PMC4713866

المؤلفون: Bart Jan Kullberg, Evangelos J. Giamarellos-Bourboulis, Daniela C. Ifrim, Liesbeth Jacobs, Jessica Quintin, Leo A. B. Joosten, Mihai G. Netea, Cisca Wijmenga, Hendrik G. Stunnenberg, Jos W. M. van der Meer, Sadia Saeed, Joost H.A. Martens, Ramnik J. Xavier, Colin Logie, Trees Jansen

المساهمون: Radboud University Medical Center [Nijmegen], Radboud university [Nijmegen], National and Kapodistrian University of Athens (NKUA), Jena University Hospital [Jena], University Medical Center Groningen [Groningen] (UMCG), Massachusetts General Hospital [Boston], Broad Institute of MIT and Harvard (BROAD INSTITUTE), Harvard Medical School [Boston] (HMS)-Massachusetts Institute of Technology (MIT)-Massachusetts General Hospital [Boston], Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI)

المصدر: Cell Host & Microbe, 12, 2, pp. 223-232
Cell Host and Microbe
Cell Host and Microbe, Elsevier, 2012, 12 (2), pp.223-232. ⟨10.1016/j.chom.2012.06.006⟩
Cell Host & Microbe, 12, 223-232
Cell Host & Microbe, 12(2), 223-232. CELL PRESS

مصطلحات موضوعية: Cancer Research, POLARIZATION, Genetics and epigenetic pathways of disease [NCMLS 6], [SDV]Life Sciences [q-bio], MESH: Monocytes, [SDV.IMM.II]Life Sciences [q-bio]/Immunology/Innate immunity, Monocytes, ACTIVATION, Mice, NATURAL-KILLER-CELLS, 0302 clinical medicine, Candida albicans, IMMUNE-RESPONSE, MESH: Animals, TRANSCRIPTION, EPIGENETIC REGULATION, Cells, Cultured, [SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology, 0303 health sciences, MESH: Cytokines, IMMUNOSUPPRESSION, Candidiasis, Health aging / healthy living Pathogenesis and modulation of inflammation [IGMD 5], Corpus albicans, MESH: Candidiasis, CROHNS-DISEASE, 3. Good health, Pathogenesis and modulation of inflammation [N4i 1], medicine.anatomical_structure, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, 030220 oncology & carcinogenesis, Cytokines, [SDV.IMM]Life Sciences [q-bio]/Immunology, Female, Reprogramming, MESH: Cells, Cultured, Biology, Invasive mycoses and compromised host Infection and autoimmunity [N4i 2], Microbiology, DENDRITIC CELLS, Article, 03 medical and health sciences, Immune system, Immunity, MESH: Mice, Inbred C57BL, Virology, Immunology and Microbiology(all), medicine, Animals, Humans, Lectins, C-Type, MESH: Mice, Molecular Biology, B cell, 030304 developmental biology, Innate immune system, MESH: Humans, Monocyte, MESH: Candida albicans, MEMORY, Pathogenesis and modulation of inflammation Infection and autoimmunity [N4i 1], biology.organism_classification, Mice, Inbred C57BL, Proto-Oncogene Proteins c-raf, Immunology, MESH: Proto-Oncogene Proteins c-raf, Parasitology, MESH: Female, MESH: Lectins, C-Type

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb213d471139242048ce17e5457d053
https://doi.org/10.1016/j.chom.2012.06.006