المؤلفون: Restrepo P; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Yong R; Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Laface I; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Tsankova N; Department of Pathology, and Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Nael K; Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Akturk G; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Sebra R; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; Sema4, a Mount Sinai venture, Stamford, Connecticut 06902, USA., Gnjatic S; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; Department of Hematology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Hormigo A; Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Losic B; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; Diabetes, Obesity and Metabolism Institute, and Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.

المصدر: Cold Spring Harbor molecular case studies [Cold Spring Harb Mol Case Stud] 2020 Apr 01; Vol. 6 (2). Date of Electronic Publication: 2020 Apr 01 (Print Publication: 2020).

نوع المنشور: Case Reports; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 101660017 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2373-2873 (Electronic) Linking ISSN: 23732873 NLM ISO Abbreviation: Cold Spring Harb Mol Case Stud Subsets: MEDLINE

مواضيع طبية MeSH: Biological Variation, Population*, Brain Neoplasms/*diagnosis , Brain Neoplasms/*etiology , Glioblastoma/*diagnosis , Glioblastoma/*etiology , Tumor Microenvironment/*immunology, Aged ; Alleles ; Antineoplastic Agents, Immunological/administration & dosage ; Antineoplastic Agents, Immunological/adverse effects ; Antineoplastic Agents, Immunological/therapeutic use ; Biomarkers, Tumor ; Biopsy ; Brain Neoplasms/drug therapy ; Clonal Evolution/genetics ; DNA Copy Number Variations ; DNA Mutational Analysis ; Female ; Gene Expression Regulation, Neoplastic ; Gene Frequency ; Genetic Heterogeneity ; Glioblastoma/drug therapy ; Humans ; Molecular Targeted Therapy ; Mutation ; Programmed Cell Death 1 Receptor/antagonists & inhibitors ; Treatment Outcome