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المؤلفون: Martin Lowe, Philipp Aurass, Marc Edwards, Wenwen Huo, Seongok Kim, Won Young Choi, Ralph R. Isberg, Elizabeth A. Creasey
المصدر: Cell Reports, Vol 37, Iss 5, Pp 109894-(2021)
Choi, W Y, Kim, S, Aurass, P, Huo, W, Creasey, E A, Edwards, M, Lowe, M & Isberg, R R 2021, ' SdhA blocks disruption of the Legionella-containing vacuole by hijacking the OCRL phosphatase ', Cell Reports, vol. 37, no. 5, 109894, pp. 109894 . https://doi.org/10.1016/j.celrep.2021.109894
Cell reportsمصطلحات موضوعية: Phosphatidylinositol 4,5-Diphosphate, bacterial pathogenesis, Endosome, QH301-705.5, Oculocerebrorenal syndrome, SDHA, GTPase, Vacuole, Article, General Biochemistry, Genetics and Molecular Biology, Legionella pneumophila, Evolution, Molecular, EEA1, Mice, Bacterial Proteins, Chlorocebus aethiops, medicine, Animals, Humans, Protein Interaction Domains and Motifs, ddc:610, Biology (General), OCRL, Flavoproteins, Chemistry, Macrophages, U937 Cells, medicine.disease, Endocytosis, Phosphoric Monoester Hydrolases, Cell biology, Protein Transport, intracellular replication, HEK293 Cells, rab GTP-Binding Proteins, endosomes, COS Cells, Host-Pathogen Interactions, Mutation, Vacuoles, vesicle trafficking, Female, Rab, Legionnaires' Disease, 610 Medizin und Gesundheit
وصف الملف: application/pdf
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المؤلفون: Tak W. Mak, Punit Saraon, Joe Eun Son, Jiaqi Yang, Zhenyu Hao, Huntley H. Chang, Taylor Gillmore, Minna Woo, Min Jeong Kim, Romario Regeenes, Yoo Jin Park, Daniella Febbraro, Chi-chung Hui, Isabella Caniggia, Soo Jung Oh, Sofia Farkona, Igor Stagljar, Tharini Sivasubramaniyam, Ana Konvalinka, Evan Pollock-Tahiri, Jonathan V. Rocheleau
المصدر: Molecular Metabolism, Vol 47, Iss, Pp 101185-(2021)
Molecular Metabolismمصطلحات موضوعية: 0301 basic medicine, Male, Programmed cell death, Fgf21, Ultraviolet Rays, Autophagosome maturation, EGFR, Skeletal muscle, 030209 endocrinology & metabolism, UVRAG, Endosomes, Mitochondrion, 03 medical and health sciences, Mice, 0302 clinical medicine, medicine, Autophagy, Animals, Homeostasis, Muscle, Skeletal, Molecular Biology, Internal medicine, Mice, Knockout, Chemistry, Tumor Suppressor Proteins, Cell Biology, medicine.disease, RC31-1245, Cell biology, ErbB Receptors, Fibroblast Growth Factors, 030104 developmental biology, medicine.anatomical_structure, Sarcopenia, Mitochondrial dynamics, Mitochondrial fission, Female, Original Article, Transcriptome
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المؤلفون: Jessica E. Young, Lauren K. Fong, Gregory A. Petsko, Harald Frankowski, Scott A. Small, Lawrence S.B. Goldstein
المصدر: Stem Cell Reports
Stem Cell Reports, Vol 10, Iss 3, Pp 1046-1058 (2018)
Stem cell reports, vol 10, iss 3مصطلحات موضوعية: 0301 basic medicine, Retromer, Endosome, Amyloid beta, Cells, Clinical Sciences, Population, Induced Pluripotent Stem Cells, tau Proteins, Disease, Endosomes, Biochemistry, Article, 03 medical and health sciences, Amyloid beta-Protein Precursor, Mice, 0302 clinical medicine, Alzheimer Disease, Genetics, Amyloid precursor protein, Animals, Humans, Phosphorylation, education, lcsh:QH301-705.5, Cells, Cultured, Neurons, lcsh:R5-920, education.field_of_study, Cultured, Amyloid beta-Peptides, biology, Cell Biology, Cell biology, Retromer complex, human induced pluripotent stem cells, Protein Transport, 030104 developmental biology, lcsh:Biology (General), biology.protein, Biochemistry and Cell Biology, Stem cell, Amyloid Precursor Protein Secretases, lcsh:Medicine (General), Alzheimer’s disease, retromer complex stabilization, 030217 neurology & neurosurgery, Developmental Biology
وصف الملف: application/pdf
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المؤلفون: Stefan Offermanns, Martin W. Werno, Christian Baumeier, Maria Rödiger, Kyungyeun Song, Michael Krauß, Deike Hesse, Nina Wettschureck, Annette Schürmann, Ilka Wilhelmi
المصدر: Molecular Metabolism, Vol 8, Iss, Pp 167-179 (2018)
Molecular Metabolism
Molecular metabolism, 8:167-179مصطلحات موضوعية: 0301 basic medicine, Male, ARFRP1, lcsh:Internal medicine, Endosome, Endocytic recycling, Endosomes, Exocytosis, 03 medical and health sciences, Mice, 3T3-L1 Cells, Adiponectin, trans-Golgi, Insulin receptor, Adipocytes, Glucose homeostasis, Animals, Humans, Adiponectin secretion, lcsh:RC31-1245, Molecular Biology, Secretory pathway, Cells, Cultured, Secretory Pathway, 030102 biochemistry & molecular biology, biology, Chemistry, ADP-Ribosylation Factors, Intracellular vesicle, Cell Biology, Receptor, Insulin, Cell biology, Mice, Inbred C57BL, Protein Transport, 030104 developmental biology, Cardiovascular and Metabolic Diseases, biology.protein, Original Article, HeLa Cells, trans-Golgi Network
وصف الملف: application/pdf; application/msword
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المؤلفون: Michael Willem, Sabyashachi Mishra, Amedeo Caflisch, Lawrence Rajendran, Philipp Koch, Kai Simons, Christian Haass, Antonio Baici, Oliver Brüstle, Saoussen Ben Halima, K. Muruga Poopathi Raja
المساهمون: University of Zurich, Rajendran, Lawrence
المصدر: Cell Reports, Vol 14, Iss 9, Pp 2127-2141 (2016)
Cell reports 14(9), 2127-2141 (2016). doi:10.1016/j.celrep.2016.01.076
Cell Reportsمصطلحات موضوعية: 0301 basic medicine, Golgi Apparatus, antagonists & inhibitors [Amyloid Precursor Protein Secretases], Bioinformatics, Substrate Specificity, Mice, Amyloid beta-Protein Precursor, metabolism [Neuregulin-1], 0302 clinical medicine, chemistry [Oligopeptides], NRG1 protein, human, metabolism [Amyloid beta-Protein Precursor], Amyloid precursor protein, drug therapy [Alzheimer Disease], Aspartic Acid Endopeptidases, chemistry [Amyloid beta-Protein Precursor], Induced pluripotent stem cell, lcsh:QH301-705.5, Cells, Cultured, biology, membrane trafficking, pharmacology [Oligopeptides], amyloid, 11359 Institute for Regenerative Medicine (IREM), metabolism [Aspartic Acid Endopeptidases], Endocytosis, 3. Good health, Transport protein, Cell biology, Protein Transport, chemistry [Amyloid Precursor Protein Secretases], Neuregulin, Alzheimer's disease, Alzheimer disease, Oligopeptides, metabolism [Endosomes], secretase, Neuregulin-1, Induced Pluripotent Stem Cells, 610 Medicine & health, Endosomes, Molecular Dynamics Simulation, metabolism [Golgi Apparatus], General Biochemistry, Genetics and Molecular Biology, OM99-2, 03 medical and health sciences, 1300 General Biochemistry, Genetics and Molecular Biology, BACE1 protein, human, mental disorders, 10019 Department of Biochemistry, medicine, Animals, Humans, ddc:610, BACE, Neuregulin 1, chemistry [Aspartic Acid Endopeptidases], enzymology [Alzheimer Disease], chemistry [Neuregulin-1], medicine.disease, metabolism [Amyloid Precursor Protein Secretases], molecular dynamics, Kinetics, 030104 developmental biology, lcsh:Biology (General), Proteolysis, biology.protein, 570 Life sciences, Amyloid Precursor Protein Secretases, APP, Protein Processing, Post-Translational, Amyloid precursor protein secretase, 030217 neurology & neurosurgery, subcellular compartmentalization
وصف الملف: ZORA125021.pdf - application/pdf
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المؤلفون: John H. Brumell, A. Proteau, Vanessa M. D'Costa, Sergio Grinstein, Laura McDonald, Rong Shi, Virginie Braun, Miroslaw Cygler, Marija Landekic
المصدر: Cell Reports, Vol 12, Iss 9, Pp 1508-1518 (2015)
مصطلحات موضوعية: Endosome, Endocytic cycle, Dynein, Molecular Sequence Data, GTPase, Plasma protein binding, Endosomes, Biology, General Biochemistry, Genetics and Molecular Biology, Mice, Bacterial Proteins, Microtubule, Animals, Humans, Amino Acid Sequence, lcsh:QH301-705.5, Adaptor Proteins, Signal Transducing, Effector, Salmonella enterica, rab7 GTP-Binding Proteins, biology.organism_classification, Cell biology, Protein Structure, Tertiary, DNA-Binding Proteins, Protein Transport, HEK293 Cells, lcsh:Biology (General), rab GTP-Binding Proteins, Microtubule-Associated Proteins, HeLa Cells, Protein Binding, Transcription Factors
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المؤلفون: Mariko Saito, Robert W. Ledeen, Maria Hui, Gusheng Wu, Kurt Masiello, Kostantin Dobrenis, Mitsuo Saito
المصدر: Journal of Lipid Research, Vol 56, Iss 8, Pp 1434-1448 (2015)
مصطلحات موضوعية: Lipopolysaccharides, Ceramide, endocrine system, Endosome, GM2/GD2 synthase knockout mice, Nerve Tissue Proteins, Endosomes, QD415-436, Biology, Biochemistry, Gene Knockout Techniques, Mice, chemistry.chemical_compound, Endocrinology, astrocyte, Gangliosides, Glial Fibrillary Acidic Protein, medicine, Animals, Dimethyl Sulfoxide, brain lipids, Research Articles, Neurons, activated microglia, Ganglioside, Microglia, Glial fibrillary acidic protein, Neurodegeneration, Brain, Cell Biology, medicine.disease, Cell biology, Mice, Inbred C57BL, carbohydrates (lipids), medicine.anatomical_structure, chemistry, inflammation, Astrocytes, Immunology, biology.protein, N-Acetylgalactosaminyltransferases, Neuroglia, lipids (amino acids, peptides, and proteins), ethanol, Lysosomes, Astrocyte
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a798e84f50dcd98d9a989ea40748298f
http://www.sciencedirect.com/science/article/pii/S0022227520355218 -
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المؤلفون: K S Vinay, Abhishek Sinha, Rohan J. Khadilkar, Arghyashree Roychowdhury Sinha, Maneesha S. Inamdar
المصدر: Cell Reports, Vol 4, Iss 4, Pp 649-658 (2013)
Cell reportsمصطلحات موضوعية: Pluripotent Stem Cells, STAT3 Transcription Factor, Endosome, Cellular differentiation, Endosomes, Article, General Biochemistry, Genetics and Molecular Biology, Mice, medicine, Animals, Drosophila Proteins, Humans, Induced pluripotent stem cell, STAT3, lcsh:QH301-705.5, Conserved Sequence, Cell Proliferation, Janus Kinases, biology, F-Box Proteins, HEK 293 cells, Membrane Proteins, JAK-STAT signaling pathway, Hematopoietic stem cell, Cell Differentiation, Hematopoietic Stem Cells, Cell biology, Protein Transport, HEK293 Cells, medicine.anatomical_structure, lcsh:Biology (General), biology.protein, Drosophila, Stem cell, Protein Binding, Signal Transduction
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المؤلفون: Ellen Sapp, Miguel Esteves, Nicholas Masso, Marian DiFiglia, Jonathan Alexander, Kathryn Chase, Antonio Valencia, Neil Aronin, Patrick Reeves, Laryssa A. Comer-Tierney, Kimberly B. Kegel, Xueyi Li
المصدر: Neurobiology of Disease, Vol 36, Iss 2, Pp 374-383 (2009)
مصطلحات موضوعية: Huntingtin, Endosome, Transferrin receptor, Striatum, Endosomes, Biology, Article, Knock-in mouse, Cell Line, lcsh:RC321-571, Mice, Mice, Neurologic Mutants, Huntington's disease, medicine, Animals, Gene Knock-In Techniques, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Cells, Cultured, Neurodegeneration, Cell Cycle, Long-term potentiation, medicine.disease, Cell biology, Disease Models, Animal, Huntington Disease, Neurology, Gene Expression Regulation, nervous system, rab GTP-Binding Proteins, Rab11, Rab, Neuroscience
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b82b3a573edd62c2094529280df7a1b4
http://www.sciencedirect.com/science/article/pii/S0969996109002216 -
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المؤلفون: Stephen D. Turley, Benny Liu, Eduardo P. Beltroy, John M. Dietschy
المصدر: Journal of Lipid Research, Vol 48, Iss 4, Pp 869-881 (2007)
مصطلحات موضوعية: medicine.medical_specialty, Endosomes, QD415-436, Biology, Biochemistry, Transaminase, Mice, chemistry.chemical_compound, Endocrinology, hepatomegaly, Ezetimibe, Niemann-Pick C1 Protein, Internal medicine, medicine, Animals, Mice, Knockout, Niemann-Pick Diseases, Membrane Glycoproteins, chylomicron cholesterol, Cell Death, Cholesterol, Liver cell, Intracellular Signaling Peptides and Proteins, Cell Biology, biliary bile acid, Lipid Metabolism, low density lipoprotein receptor, Sterol, Small intestine, medicine.anatomical_structure, chemistry, hepatic dysfunction, LDL receptor, Hepatocytes, lipids (amino acids, peptides, and proteins), NPC1, Carrier Proteins, Lysosomes, small intestine, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5007a15a866c2a84aa90c670dbc597dd
http://www.sciencedirect.com/science/article/pii/S0022227520434406
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