المؤلفون: Zekavat SM; Department of Ophthalmology and Visual Science, Yale School of Medicine, New Haven, Connecticut; Computational Biology & Bioinformatics Program, Yale University, New Haven, Connecticut; Program in Medical and Population Genetics and Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, Massachusetts; Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts., Sekimitsu S; Tufts University School of Medicine, Boston, Massachusetts., Ye Y; Computational Biology & Bioinformatics Program, Yale University, New Haven, Connecticut., Raghu V; Program in Medical and Population Genetics and Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, Massachusetts; Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Cardiovascular Imaging Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts., Zhao H; Computational Biology & Bioinformatics Program, Yale University, New Haven, Connecticut; School of Public Health, Yale University, New Haven, Connecticut., Elze T; Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts., Segrè AV; Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts., Wiggs JL; Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts., Natarajan P; Program in Medical and Population Genetics and Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, Massachusetts; Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts., Del Priore L; Department of Ophthalmology and Visual Science, Yale School of Medicine, New Haven, Connecticut., Zebardast N; Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts., Wang JC; Department of Ophthalmology and Visual Science, Yale School of Medicine, New Haven, Connecticut; Northern California Retina Vitreous Associates, Mountain View, California. Electronic address: jay.wang@yale.edu.

المصدر: Ophthalmology [Ophthalmology] 2022 Jun; Vol. 129 (6), pp. 694-707. Date of Electronic Publication: 2022 Feb 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7802443 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-4713 (Electronic) Linking ISSN: 01616420 NLM ISO Abbreviation: Ophthalmology Subsets: MEDLINE

مواضيع طبية MeSH: Macular Degeneration*/diagnosis , Macular Degeneration*/epidemiology , Macular Degeneration*/genetics , Tomography, Optical Coherence*/methods, Adult ; Aged ; Biological Specimen Banks ; Biomarkers ; Cohort Studies ; Female ; High-Temperature Requirement A Serine Peptidase 1/genetics ; Humans ; Male ; Middle Aged ; Retinal Pigment Epithelium ; United Kingdom/epidemiology

المؤلفون: Zebardast N; Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts. Electronic address: Nazlee_Zebardast@meei.harvard.edu., Sekimitsu S; Tufts University School of Medicine, Boston, Massachusetts., Wang J; Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts; Ocular Genomics Institute, Harvard Medical School, Boston, Massachusetts., Elze T; Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts., Gharahkhani P; Statistical Genetics Group, Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia., Cole BS; Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts; Ocular Genomics Institute, Harvard Medical School, Boston, Massachusetts., Lin MM; Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts., Segrè AV; Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts; Ocular Genomics Institute, Harvard Medical School, Boston, Massachusetts., Wiggs JL; Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts; Ocular Genomics Institute, Harvard Medical School, Boston, Massachusetts.

مؤلفون مشاركون: International Glaucoma Genetics Consortium

المصدر: Ophthalmology [Ophthalmology] 2021 Sep; Vol. 128 (9), pp. 1300-1311. Date of Electronic Publication: 2021 Mar 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7802443 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-4713 (Electronic) Linking ISSN: 01616420 NLM ISO Abbreviation: Ophthalmology Subsets: MEDLINE

مواضيع طبية MeSH: Mutation*, Cytoskeletal Proteins/*genetics , Eye Proteins/*genetics , Glaucoma, Open-Angle/*genetics , Glycoproteins/*genetics , Multifactorial Inheritance/*genetics, Adult ; Aged ; Biological Specimen Banks ; Cross-Sectional Studies ; Female ; Genome-Wide Association Study ; Glaucoma, Open-Angle/diagnosis ; Glaucoma, Open-Angle/physiopathology ; Humans ; Intraocular Pressure ; Male ; Middle Aged ; Nerve Fibers/pathology ; Penetrance ; Retinal Ganglion Cells/pathology ; Tomography, Optical Coherence ; United Kingdom