المؤلفون: Devineni D; Janssen Research & Development, LLC, Raritan, New Jersey. Electronic address: ddevinen@its.jnj.com., Curtin CR; Janssen Research & Development, LLC, Raritan, New Jersey., Marbury TC; Orlando Clinical Research Center, Orlando, Florida., Smith W; New Orleans Center for Clinical Research, The University of Tennessee Medical Center, Knoxville, Tennessee., Vaccaro N; Janssen Research & Development, LLC, San Diego, California., Wexler D; Janssen Research & Development, LLC, San Diego, California., Vandebosch A; Janssen Research & Development, a division of Janssen Pharmaceutica NV, Beerse, Belgium., Rusch S; Janssen Research & Development, a division of Janssen Pharmaceutica NV, Beerse, Belgium., Stieltjes H; Janssen Research & Development, a division of Janssen Pharmaceutica NV, Beerse, Belgium., Wajs E; Janssen Research & Development, a division of Janssen Pharmaceutica NV, Beerse, Belgium.

المصدر: Clinical therapeutics [Clin Ther] 2015 Mar 01; Vol. 37 (3), pp. 610-628.e4. Date of Electronic Publication: 2015 Feb 03.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Excerpta Medica Country of Publication: United States NLM ID: 7706726 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-114X (Electronic) Linking ISSN: 01492918 NLM ISO Abbreviation: Clin Ther Subsets: MEDLINE

مواضيع طبية MeSH: Canagliflozin/*pharmacokinetics , Diabetes Mellitus, Type 2/*drug therapy , Liver Diseases/*complications , Renal Insufficiency/*complications, Adult ; Aged ; Area Under Curve ; Female ; Glucose/metabolism ; Humans ; Kidney Failure, Chronic/complications ; Male ; Middle Aged ; Sodium-Glucose Transporter 2 Inhibitors

المؤلفون: Devineni D; Janssen Research & Development, LLC, Raritan, New Jersey. Electronic address: ddevinen@its.jnj.com., Vaccaro N; Janssen Research & Development, LLC, Raritan, New Jersey., Polidori D; Janssen Research & Development, LLC, San Diego, California., Rusch S; Janssen Research & Development, Beerse, Belgium., Wajs E; Janssen Research & Development, Beerse, Belgium.

المصدر: Clinical therapeutics [Clin Ther] 2014 May; Vol. 36 (5), pp. 698-710. Date of Electronic Publication: 2014 Apr 13.

نوع المنشور: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Excerpta Medica Country of Publication: United States NLM ID: 7706726 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-114X (Electronic) Linking ISSN: 01492918 NLM ISO Abbreviation: Clin Ther Subsets: MEDLINE

مواضيع طبية MeSH: Drug Therapy, Combination/*adverse effects , Glucosides/*administration & dosage , Glucosides/*pharmacokinetics , Hydrochlorothiazide/*pharmacology , Thiophenes/*administration & dosage , Thiophenes/*pharmacokinetics, Adolescent ; Adult ; Blood/drug effects ; Canagliflozin ; Drug Administration Schedule ; Female ; Glucosides/adverse effects ; Healthy Volunteers ; Humans ; Hydrochlorothiazide/administration & dosage ; Male ; Middle Aged ; Sodium-Glucose Transporter 2 Inhibitors ; Thiophenes/adverse effects ; Urine/physiology ; Young Adult