المؤلفون: Miao Y; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, School of Pharmacy, Anhui Medical University, Hefei, Anhui Province, China.; Anhui Key Laboratory of Bioactivity of Natural Products, Institute for Liver Diseases of Anhui Medical University, Anhui Medical University, Hefei, Anhui Province, China., Peng L; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, School of Pharmacy, Anhui Medical University, Hefei, Anhui Province, China.; Anhui Key Laboratory of Bioactivity of Natural Products, Institute for Liver Diseases of Anhui Medical University, Anhui Medical University, Hefei, Anhui Province, China., Chen Z; Department of Pharmacy, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Anhui Provincial Hospital, Hefei, Anhui Province, China., Hu Y; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, School of Pharmacy, Anhui Medical University, Hefei, Anhui Province, China.; Anhui Key Laboratory of Bioactivity of Natural Products, Institute for Liver Diseases of Anhui Medical University, Anhui Medical University, Hefei, Anhui Province, China., Tao L; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, School of Pharmacy, Anhui Medical University, Hefei, Anhui Province, China.; Anhui Key Laboratory of Bioactivity of Natural Products, Institute for Liver Diseases of Anhui Medical University, Anhui Medical University, Hefei, Anhui Province, China., Yao Y; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, School of Pharmacy, Anhui Medical University, Hefei, Anhui Province, China.; Anhui Key Laboratory of Bioactivity of Natural Products, Institute for Liver Diseases of Anhui Medical University, Anhui Medical University, Hefei, Anhui Province, China., Wu Y; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, School of Pharmacy, Anhui Medical University, Hefei, Anhui Province, China.; Anhui Key Laboratory of Bioactivity of Natural Products, Institute for Liver Diseases of Anhui Medical University, Anhui Medical University, Hefei, Anhui Province, China., Yang D; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, School of Pharmacy, Anhui Medical University, Hefei, Anhui Province, China.; Anhui Key Laboratory of Bioactivity of Natural Products, Institute for Liver Diseases of Anhui Medical University, Anhui Medical University, Hefei, Anhui Province, China., Xu T; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, School of Pharmacy, Anhui Medical University, Hefei, Anhui Province, China.; Anhui Key Laboratory of Bioactivity of Natural Products, Institute for Liver Diseases of Anhui Medical University, Anhui Medical University, Hefei, Anhui Province, China.

المصدر: Expert opinion on therapeutic targets [Expert Opin Ther Targets] 2023 Feb; Vol. 27 (2), pp. 121-132. Date of Electronic Publication: 2023 Feb 28.

نوع المنشور: Review; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101127833 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7631 (Electronic) Linking ISSN: 14728222 NLM ISO Abbreviation: Expert Opin Ther Targets Subsets: MEDLINE

مواضيع طبية MeSH: Cyclic Nucleotide Phosphodiesterases, Type 4*/metabolism , Cyclic Nucleotide Phosphodiesterases, Type 4*/pharmacology , Neoplasms*/drug therapy, Humans ; Apoptosis ; Signal Transduction

المؤلفون: Tsiogkas SG; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece., Karamitrou EK; Primary Health Center of Mouzaki, Karditsa, Greece., Grammatikopoulou MG; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece., Zafiriou E; Department of Dermatology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece., Bogdanos DP; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.

المصدر: Current medical research and opinion [Curr Med Res Opin] 2024 Feb; Vol. 40 (2), pp. 155-163. Date of Electronic Publication: 2024 Jan 24.

نوع المنشور: Meta-Analysis; Systematic Review; Journal Article

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 0351014 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-4877 (Electronic) Linking ISSN: 03007995 NLM ISO Abbreviation: Curr Med Res Opin Subsets: MEDLINE

مواضيع طبية MeSH: Phosphodiesterase 4 Inhibitors*/therapeutic use , Psoriasis*/drug therapy, Thalidomide/*analogs & derivatives, Humans ; Cyclic Nucleotide Phosphodiesterases, Type 4/therapeutic use ; TYK2 Kinase/therapeutic use ; Scalp ; Tyrosine/therapeutic use ; Severity of Illness Index ; Treatment Outcome ; Randomized Controlled Trials as Topic

المؤلفون: Gao L; Department of Rehabilitation Medicine, Wuhan Hospital of Traditional Chinese and Western Medicine, Wuhan, China., Wang X; Department of Rehabilitation Medicine, Wuhan Hospital of Traditional Chinese and Western Medicine, Wuhan, China., Xiong J; Department of Rehabilitation Medicine, Wuhan Hospital of Traditional Chinese and Western Medicine, Wuhan, China., Ma Y; Department of Rehabilitation Medicine, Wuhan Hospital of Traditional Chinese and Western Medicine, Wuhan, China.

المصدر: Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2022 Oct; Vol. 44 (5), pp. 682-692. Date of Electronic Publication: 2022 May 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8800150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2513 (Electronic) Linking ISSN: 08923973 NLM ISO Abbreviation: Immunopharmacol Immunotoxicol Subsets: MEDLINE

مواضيع طبية MeSH: MicroRNAs*/genetics , MicroRNAs*/metabolism , Osteoarthritis*/genetics , Osteoarthritis*/metabolism, Annexin A5/metabolism ; Apoptosis ; Biotin/metabolism ; Caspase 3/metabolism ; Chondrocytes/metabolism ; Collagen Type II/metabolism ; Cyclic Nucleotide Phosphodiesterases, Type 4/genetics ; Cyclic Nucleotide Phosphodiesterases, Type 4/metabolism ; Extracellular Matrix/metabolism ; Fluoresceins/metabolism ; Humans ; Interleukin-1beta/metabolism ; Interleukin-6/metabolism ; Interleukin-8 ; Isothiocyanates ; Matrix Metalloproteinase 13/metabolism ; Poly (ADP-Ribose) Polymerase-1/metabolism ; RNA, Circular/genetics ; SOX9 Transcription Factor ; Thrombospondins/metabolism ; bcl-2-Associated X Protein/metabolism

المؤلفون: Md Idris MH; Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA (UiTM) Selangor Branch, Puncak Alam Campus, Selangor, Malaysia., Mohd Amin SN; Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA (UiTM) Selangor Branch, Puncak Alam Campus, Selangor, Malaysia., Mohd Amin SN; Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA (UiTM) Selangor Branch, Puncak Alam Campus, Selangor, Malaysia., Wibowo A; Faculty of Applied Science, Universiti Teknologi MARA (UiTM) Pahang Branch, Jengka Campus, Pahang, Malaysia., Zakaria ZA; Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia (UPM), Serdang, Malaysia., Shaameri Z; Organic Synthesis Laboratory, Institute of Science (IOS), Universiti Teknologi MARA (UiTM) Selangor Branch, Puncak Alam Campus, Selangor, Malaysia., Hamzah AS; Organic Synthesis Laboratory, Institute of Science (IOS), Universiti Teknologi MARA (UiTM) Selangor Branch, Puncak Alam Campus, Selangor, Malaysia., Selvaraj M; School of Engineering, Monash University (Malaysia Campus), Bandar Sunway, Malaysia., Teh LK; Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA (UiTM) Selangor Branch, Puncak Alam Campus, Selangor, Malaysia., Salleh MZ; Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA (UiTM) Selangor Branch, Puncak Alam Campus, Selangor, Malaysia.

المصدر: Journal of receptor and signal transduction research [J Recept Signal Transduct Res] 2022 Aug; Vol. 42 (4), pp. 325-337. Date of Electronic Publication: 2021 Jul 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9509432 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-4281 (Electronic) Linking ISSN: 10799893 NLM ISO Abbreviation: J Recept Signal Transduct Res Subsets: MEDLINE

مواضيع طبية MeSH: Arachidonate 5-Lipoxygenase*/genetics , Arachidonate 5-Lipoxygenase*/metabolism , Flavones*/pharmacology, Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Cyclic Nucleotide Phosphodiesterases, Type 4/genetics ; Cyclic Nucleotide Phosphodiesterases, Type 4/metabolism ; Cyclooxygenase 2/genetics ; Cyclooxygenase 2 Inhibitors/pharmacology ; Lipoxygenase Inhibitors/pharmacology ; Molecular Docking Simulation ; Molecular Structure ; Phosphodiesterase Inhibitors/pharmacology ; Structure-Activity Relationship

المؤلفون: Garcia-Gonzalez MA; Departamento de Farmacia, Benemerita Universidad Autonoma de Puebla, Laboratorio de Farmacia Clinica, Edificio FCQ10, Ciudad Universitaria, Col. Jardines de San Manuel, Puebla, Mexico., Vallejo-Ruiz V; Instituto Mexicano del Seguro Social, Centro de Investigación Biomédica de Oriente, Laboratorio de Biología Molecular, Puebla, Mexico., Atonal-Flores F; Departamento de Fisiología, Benemérita Universidad Autónoma de Puebla, Facultad de Medicina, Metepec, Mexico., Flores-Hernandez J; Laboratorio de Neuromodulación, Benemerita Universidad Autonoma de Puebla, Fisiología, Puebla,Mexico., Torres-Ramírez O; Departamento de Farmacia, Benemérita Universidad Autónoma de Puebla, Facultad de Ciencias Químicas, Puebla, Mexico., Diaz-Fonsecae A; Departamento de Farmacia, Benemérita Universidad Autónoma de Puebla, Facultad de Ciencias Químicas, Puebla, Mexico., Perez Vizcaino F; Departamento de Farmacología y Toxicología, Universidad Complutense de Madrid, Escuela de Medicina, Puebla,Mexico., Lopez-Lopez JG; Departamento de Farmacia, Benemerita Universidad Autonoma de Puebla, Laboratorio de Farmacia Clinica, Edificio FCQ10, Ciudad Universitaria, Col. Jardines de San Manuel, Puebla, Mexico.

المصدر: Clinical and experimental hypertension (New York, N.Y. : 1993) [Clin Exp Hypertens] 2022 May 19; Vol. 44 (4), pp. 355-365. Date of Electronic Publication: 2022 Mar 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9305929 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-6006 (Electronic) Linking ISSN: 10641963 NLM ISO Abbreviation: Clin Exp Hypertens Subsets: MEDLINE

مواضيع طبية MeSH: Hypertension, Pulmonary*/drug therapy , Hypertension, Pulmonary*/etiology , Hypertension, Pulmonary*/prevention & control , Diabetes Mellitus, Experimental*/complications , Diabetes Mellitus, Experimental*/drug therapy , Diabetes Mellitus, Type 1*/complications, Rats ; Male ; Animals ; Sildenafil Citrate/pharmacology ; Hypertrophy, Right Ventricular/etiology ; Hypertrophy, Right Ventricular/prevention & control ; Heart Rate ; Cyclic Nucleotide Phosphodiesterases, Type 5 ; Rats, Sprague-Dawley ; Disease Models, Animal

المؤلفون: Bhatia P; CNS Research Lab., Pharmacology Division, Department of Pharmaceutical Sciences and Drug Research, Faculty of Medicine, Punjabi University, Patiala, Punjab, India., Singh N; Department of Pharmaceutical Sciences and Drug Research, Faculty of Medicine, Punjabi University, Patiala, Punjab, India.

المصدر: The International journal of neuroscience [Int J Neurosci] 2022 Apr; Vol. 132 (4), pp. 384-396. Date of Electronic Publication: 2020 Sep 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 0270707 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1563-5279 (Electronic) Linking ISSN: 00207454 NLM ISO Abbreviation: Int J Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Dementia, Vascular*/drug therapy , Dementia, Vascular*/etiology , Hyperhomocysteinemia*/chemically induced , Hyperhomocysteinemia*/complications , Hyperhomocysteinemia*/drug therapy , Tadalafil*/therapeutic use, Acetylcholine ; Acetylcholinesterase/metabolism ; Animals ; Brain/metabolism ; Cyclic Nucleotide Phosphodiesterases, Type 5 ; Maze Learning ; Memory Disorders/chemically induced ; Memory Disorders/drug therapy ; Methionine ; Nitrites/blood ; Oxidative Stress ; Phosphodiesterase 5 Inhibitors ; Rats ; Rats, Wistar

المؤلفون: Liu Z; Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou, China., Liu M; Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou, China., Cao Z; Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou, China., Qiu P; Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou, China., Song G; Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou, China.

المصدر: Expert opinion on therapeutic patents [Expert Opin Ther Pat] 2022 Mar; Vol. 32 (3), pp. 261-278. Date of Electronic Publication: 2022 Jan 17.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9516419 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7674 (Electronic) Linking ISSN: 13543776 NLM ISO Abbreviation: Expert Opin Ther Pat Subsets: MEDLINE

مواضيع طبية MeSH: Nervous System Diseases*/drug therapy , Phosphodiesterase 4 Inhibitors*/adverse effects, Cyclic Nucleotide Phosphodiesterases, Type 4/therapeutic use ; Humans ; Patents as Topic

المؤلفون: Yamaki K; Department of Pharmacology, Kobe Pharmaceutical University, Kobe, Hyogo, Japan., Li X, Hossain MA, Alam AH, Taneda S, Yanagisawa R, Takano H, Yoshino S

المصدر: Immunological investigations [Immunol Invest] 2007; Vol. 36 (2), pp. 131-45.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8504629 Publication Model: Print Cited Medium: Print ISSN: 0882-0139 (Print) Linking ISSN: 08820139 NLM ISO Abbreviation: Immunol Invest Subsets: MEDLINE

مواضيع طبية MeSH: 3',5'-Cyclic-AMP Phosphodiesterases/*antagonists & inhibitors , Antirheumatic Agents/*pharmacology , Arthritis, Experimental/*prevention & control , Phosphodiesterase Inhibitors/*pharmacology , Rolipram/*pharmacology, 3',5'-Cyclic-AMP Phosphodiesterases/immunology ; 3',5'-Cyclic-AMP Phosphodiesterases/metabolism ; Animals ; Arthritis, Experimental/enzymology ; Arthritis, Experimental/immunology ; Auranofin/pharmacology ; Cyclic Nucleotide Phosphodiesterases, Type 4 ; Dexamethasone/pharmacology ; Female ; Immunoglobulin G/immunology ; Indomethacin/pharmacology ; Interferon-gamma/immunology ; Interleukin-10/immunology ; Methotrexate/pharmacology ; Mice ; Mice, Inbred DBA ; Ovalbumin/immunology ; Penicillamine/pharmacology ; Th1 Cells/drug effects ; Th1 Cells/immunology ; Th2 Cells/drug effects ; Th2 Cells/immunology

المؤلفون: Lehnart SE; Columbia University, Clyde and Helen Wu Center for Molecular Cardiology, Department of Physiology and Cellular Biophysics, New York, NY 10032, USA., Marks AR

المصدر: Expert opinion on therapeutic targets [Expert Opin Ther Targets] 2006 Oct; Vol. 10 (5), pp. 677-88.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101127833 Publication Model: Print Cited Medium: Internet ISSN: 1744-7631 (Electronic) Linking ISSN: 14728222 NLM ISO Abbreviation: Expert Opin Ther Targets Subsets: MEDLINE

مواضيع طبية MeSH: 3',5'-Cyclic-AMP Phosphodiesterases/*metabolism , Heart Failure/*enzymology, 3',5'-Cyclic-AMP Phosphodiesterases/antagonists & inhibitors ; 3',5'-Cyclic-AMP Phosphodiesterases/chemistry ; Animals ; Cyclic Nucleotide Phosphodiesterases, Type 4 ; Heart Diseases/drug therapy ; Heart Diseases/enzymology ; Heart Failure/drug therapy ; Humans ; Phosphodiesterase Inhibitors/administration & dosage

المؤلفون: Zhang KY; Plexxikon, Inc., 91 Bolivar Drive, Berkeley, CA 94710, USA. kzhang@plexxikon.com, Ibrahim PN, Gillette S, Bollag G

المصدر: Expert opinion on therapeutic targets [Expert Opin Ther Targets] 2005 Dec; Vol. 9 (6), pp. 1283-305.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101127833 Publication Model: Print Cited Medium: Internet ISSN: 1744-7631 (Electronic) Linking ISSN: 14728222 NLM ISO Abbreviation: Expert Opin Ther Targets Subsets: MEDLINE

مواضيع طبية MeSH: 3',5'-Cyclic-AMP Phosphodiesterases/*physiology , Drug Delivery Systems/*methods, 3',5'-Cyclic-AMP Phosphodiesterases/antagonists & inhibitors ; 3',5'-Cyclic-AMP Phosphodiesterases/chemistry ; 3',5'-Cyclic-AMP Phosphodiesterases/metabolism ; Animals ; Cyclic Nucleotide Phosphodiesterases, Type 4 ; Humans ; Intracellular Fluid/enzymology ; Organ Specificity/physiology ; Phosphodiesterase Inhibitors/administration & dosage ; Phosphodiesterase Inhibitors/chemistry ; Structure-Activity Relationship