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1
المصدر: Surgeries, Vol 2, Iss 22, Pp 216-230 (2021)
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, RD1-811, medicine.medical_treatment, pancreatic cancer, 03 medical and health sciences, 0302 clinical medicine, Quality of life (healthcare), Pancreatic cancer, medicine, In patient, Intensive care medicine, business.industry, anti-inflammatory diet, medicine.disease, integrative surgery, Obesity, Clinical trial, 030104 developmental biology, 030220 oncology & carcinogenesis, Pancreatectomy, Surgery, Integrative medicine, pancreatectomy, business, Ketogenic diet
الوصف: Introduction: Integrative medicine (IM) is a relatively new field where non-traditional therapies with peer-reviewed evidence are incorporated or integrated with more traditional approaches. Methods: A systematic review of the literature from the last 10 years was done by searching clinical trials and randomized-controlled trials on Pubmed that discuss nutrition, supplementation, and lifestyle changes associated with “Pancreatic Cancer.” Results: Only 50 articles ultimately met the inclusion criteria for this review. A total of 15 articles discussed the role of obesity and 10 discussed the influence of stress in increasing the risk of pancreatic cancer. Six discussed the potential beneficial role of Vitamins, 5 of cannabinoids, 4 an anti-inflammatory diet, 3 of nut consumption, 2 of green tea consumption, 2 of curcumin supplementation, 1 role of melatonin, and 1 of probiotics. One article each was found on the theoretical benefits of adhering to either a Mediterranean or ketogenic diet. Discussion: As more surgeons become interested in IM, it is hoped that more diseases where the curative treatment is mainly surgical can benefit from the all-encompassing principles of IM in an effort to improve quality of life and survival in patients with pancreatic cancer.
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f57bf4adec6606d38c37f7eca49ff748
https://doi.org/10.3390/surgeries2020022 -
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المؤلفون: Randall G. Evans, Leigh Wagner, Jeanne Drisko, Anna Esparham
المصدر: Children, Vol 1, Iss 2, Pp 186-207 (2014)
Childrenمصطلحات موضوعية: Research design, medicine.medical_specialty, medicine, medicine.medical_treatment, Alternative medicine, microbiome, Review, Attention deficit hyperactivity disorder, ADHD, integrative, Psychiatry, business.industry, nutrient, approach, lcsh:RJ1-570, Cognition, lcsh:Pediatrics, neurofeedback, medicine.disease, Stimulant, Neuropsychiatric disorder, pediatric, Pediatrics, Perinatology and Child Health, Integrative medicine, Neurofeedback, business, diet, environment
الوصف: Attention deficit hyperactivity disorder (ADHD) is the most common neuropsychiatric disorder in children and is increasing in prevalence. There has also been a related increase in prescribing stimulant medication despite some controversy whether ADHD medication makes a lasting difference in school performance or achievement. Families who are apprehensive about side effects and with concerns for efficacy of medication pursue integrative medicine as an alternative or adjunct to pharmacologic and cognitive behavioral treatment approaches. Integrative medicine incorporates evidence-based medicine, both conventional and complementary and alternative therapies, to deliver personalized care to the patient, emphasizing diet, nutrients, gut health, and environmental influences as a means to decrease symptoms associated with chronic disorders. Pediatric integrative medicine practitioners are increasing in number throughout the United States because of improvement in patient health outcomes. However, limited funding and poor research design interfere with generalizable treatment approaches utilizing integrative medicine. The use of research designs originally intended for drugs and procedures are not suitable for many integrative medicine approaches. This article serves to highlight integrative medicine approaches in use today for children with ADHD, including dietary therapies, nutritional supplements, environmental hygiene, and neurofeedback.
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb114e4d18876e6150d639682dfb5810
http://www.mdpi.com/2227-9067/1/2/186 -
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المؤلفون: Melanie Anheyer, Marion Eckert
المصدر: Children
Volume 5
Issue 8
Children, Vol 5, Iss 8, p 102 (2018)مصطلحات موضوعية: Service (systems architecture), Prevention education, medicine.medical_treatment, media_common.quotation_subject, complex mixtures, Article, PIMR, 03 medical and health sciences, 0302 clinical medicine, Need to know, 030225 pediatrics, medicine, Pilot program, kindergarten, 030212 general & internal medicine, Hydrotherapy, media_common, Kneipp, Medical education, lcsh:RJ1-570, lcsh:Pediatrics, equipment and supplies, Treatment modality, Pediatrics, Perinatology and Child Health, bacteria, Integrative medicine, Consciousness, Psychology
الوصف: Pediatric integrative medicine focuses on the whole child and the environment in which the child grows up during the treatment of a child&rsquo
s illness. Nowadays, many different treatment modalities are applied even in children, and doctors need to know about them and, ideally, be able to apply different approaches in the process of treating a child themselves. The program Pediatric Integrative Medicine in Residency (PIMR) already provides residents with several tools to provide this kind of service for the child. In our PIMR pilot program in Germany, we chose to diversify our knowledge about treatment and prevention options by visiting a Kneipp-certified kindergarten in Germany. The philosophy of Sebastian Kneipp focuses on five pillars of health, which incorporate aspects of prevention, self-awareness, self-responsibility, and consciousness of health by means of hydrotherapy, herbal medicine, exercise, nutrition, and lifestyle-medicine. These are being taught to the children during the early years they spend in kindergarten, and represent integral parts of integrative medicine. Integration of Kneipp-based health programs within a kindergarten setting can work well and provides an effective means of early prevention education in childhood.وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89801cb5bfd9622d1c7bd3bc23c3bc67
https://doi.org/10.3390/children5080102 -
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المؤلفون: Rajal G. Cohen, Jordan J. Becker, Tara L. McIsaac, Shawn L. Copeland
المصدر: Applied Sciences, Vol 11, Iss 4640, p 4640 (2021)
Applied Sciences
Volume 11
Issue 10مصطلحات موضوعية: integrative medicine, medicine.medical_specialty, electromyography, Technology, QH301-705.5, medicine.medical_treatment, QC1-999, CCFT, Psychological intervention, Flexion Test, Electromyography, rehabilitation, 03 medical and health sciences, 0302 clinical medicine, self-care, medicine, General Materials Science, 030212 general & internal medicine, Alexander technique, Biology (General), Instrumentation, Video game, QD1-999, posture, Fluid Flow and Transfer Processes, Neck pain, Rehabilitation, cranio-cervical flexion test, Muscle fatigue, medicine.diagnostic_test, exercise, business.industry, Process Chemistry and Technology, Physics, General Engineering, Engineering (General). Civil engineering (General), Computer Science Applications, Chemistry, Physical therapy, muscle fatigue, medicine.symptom, TA1-2040, business, self-efficacy, 030217 neurology & neurosurgery
الوصف: Background: Alexander technique private lessons have been shown to reduce chronic neck pain and are thought to work by different mechanisms than exercise. Group classes may also be effective and would be cost-effective. Design: A two-group pre-test/post-test design. Participants were assigned to either a general Alexander technique class or an exercise class designed to target neck pain. Both groups met over 5 weeks for two 60 min sessions/week. Participants: A total of 16 participants with chronic neck pain (aged 50+/−16 years) completed this study. Interventions: The Alexander class used awareness-building methods to teach participants to reduce habitual tension during everyday activities. The exercise class was based on physical therapy standard of care to strengthen neck and back muscles thought to be important for posture. Measures: We assessed neck pain/disability, pain self-efficacy, activation of the sternocleidomastoid muscles during the cranio-cervical flexion test, and posture while participants played a video game. Results: Both groups reported decreased neck pain/disability after the interventions. Sternocleidomastoid activation decreased only in the Alexander group. Conclusion: In this small preliminary study, Alexander classes were at least as effective as exercise classes in reducing neck pain and seemed to work via a different mechanism. Larger, multi-site studies are justified.
وصف الملف: application/pdf
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المؤلفون: Jennifer J. Dilts, Tammie Wingert, Anne Herbert, Emily Pierzchalski, Madeline Boorigie, Mark Connelly, Anna Esparham, Jennifer Bickel, Catherine Tran
المصدر: Children, Vol 5, Iss 6, p 74 (2018)
Childrenمصطلحات موضوعية: integrative medicine, medicine.medical_specialty, Hypnosis, complementary therapies, clinic model, medicine.medical_treatment, Specialty, Review, Biofeedback, 03 medical and health sciences, 0302 clinical medicine, Acupuncture, Medicine, migraine, 030212 general & internal medicine, implementation, business.industry, lcsh:RJ1-570, lcsh:Pediatrics, Pediatric headache, medicine.disease, pediatric, Migraine, Family medicine, Pediatrics, Perinatology and Child Health, mind-body, Integrative medicine, business, headache, 030217 neurology & neurosurgery, multidisciplinary, Aromatherapy
الوصف: The demand for integrative medicine has risen in recent years as research has demonstrated the efficacy of such treatments. The public has also become more conscientious of the potential limitations of conventional treatment alone. Because primary headache syndromes are often the culmination of genetics, lifestyle, stress, trauma, and environmental factors, they are best treated with therapies that are equally multifaceted. The Children’s Mercy Hospital, Kansas City, Missouri Headache Clinic has successfully incorporated integrative therapies including nutraceuticals, acupuncture, aromatherapy, biofeedback, relaxation training, hypnosis, psychology services, and lifestyle recommendations for headache management. This paper provides a detailed review of the implementation of integrative therapies for headache treatment and discusses examples through case studies. It can serve as a model for other specialty settings intending to incorporate all evidenced-based practices, whether complementary or conventional.
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a971ff20b44d3712c14b47cf461f5556
http://www.mdpi.com/2227-9067/5/6/74 -
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المؤلفون: Andrew Warmuth, Kavita Desai Dakoji, Cyndee Daughtry, Craig Schulz, Stefan J. Friedrichsdorf, James Giordano
المصدر: Children
Children, Vol 3, Iss 4, p 42 (2016)مصطلحات موضوعية: Biopsychosocial model, medicine.medical_specialty, Abdominal pain, medicine.medical_treatment, pediatric pain clinic, Review, biopsychosocial, 03 medical and health sciences, 0302 clinical medicine, Physical medicine and rehabilitation, children, medicine, interdisciplinary treatment, adolescents, 030212 general & internal medicine, primary pain disorder, Rehabilitation, business.industry, lcsh:RJ1-570, Chronic pain, lcsh:Pediatrics, medicine.disease, Pain Clinics, Joint pain, Pediatrics, Perinatology and Child Health, Physical therapy, Pain catastrophizing, Integrative medicine, medicine.symptom, chronic pain, business, 030217 neurology & neurosurgery
الوصف: Primary pain disorders (formerly “functional pain syndromes”) are common, under-diagnosed and under-treated in children and teenagers. This manuscript reviews key aspects which support understanding the development of pediatric chronic pain, points to the current pediatric chronic pain terminology, addresses effective treatment strategies, and discusses the evidence-based use of pharmacology. Common symptoms of an underlying pain vulnerability present in the three most common chronic pain disorders in pediatrics: primary headaches, centrally mediated abdominal pain syndromes, and/or chronic/recurrent musculoskeletal and joint pain. A significant number of children with repeated acute nociceptive pain episodes develop chronic pain in addition to or as a result of their underlying medical condition “chronic-on-acute pain.” We provide description of the structure and process of our interdisciplinary, rehabilitative pain clinic in Minneapolis, Minnesota, USA with accompanying data in the treatment of chronic pain symptoms that persist beyond the expected time of healing. An interdisciplinary approach combining (1) rehabilitation; (2) integrative medicine/active mind-body techniques; (3) psychology; and (4) normalizing daily school attendance, sports, social life and sleep will be presented. As a result of restored function, pain improves and commonly resolves. Opioids are not indicated for primary pain disorders, and other medications, with few exceptions, are usually not first-line therapy.
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2977be78c5e4b6d5be3732c033f0d1b0
https://doi.org/10.3390/children3040042 -
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المؤلفون: Jin-Yi Wu, Ling-Ling Yang, Ming-Shun Wu, Ganbolor Jargalsaikhan, Yen-Chou Chen
المصدر: Molecules, Vol 26, Iss 1217, p 1217 (2021)
Molecules
Volume 26
Issue 5مصطلحات موضوعية: Antioxidant, antioxidant, DPPH, medicine.medical_treatment, Flavonoid, Rumex crispus L, Ethyl acetate, Pharmaceutical Science, Antioxidants, Analytical Chemistry, chemistry.chemical_compound, 0302 clinical medicine, Drug Discovery, Tumor Cells, Cultured, Gallic acid, Food science, Rheum undulatum L, chemistry.chemical_classification, 0303 health sciences, ABTS, Hep G2 Cells, Phytochemical, Chemistry (miscellaneous), 030220 oncology & carcinogenesis, Molecular Medicine, Rhubarb, Cell Survival, Taiwan, Article, liver cancer, lcsh:QD241-441, 03 medical and health sciences, Structure-Activity Relationship, Picrates, lcsh:Organic chemistry, medicine, Humans, Benzothiazoles, Physical and Theoretical Chemistry, Rheum, 030304 developmental biology, Cell Proliferation, Dose-Response Relationship, Drug, Plant Extracts, Organic Chemistry, Biphenyl Compounds, Mongolia, phytochemicals, Antineoplastic Agents, Phytogenic, chemistry, Emodin, Drug Screening Assays, Antitumor, Sulfonic Acids
الوصف: The Mongolian rhubarb—Rheum undulatum L. (RU)—and Rumex crispus L. (RC)—a Taiwanese local rhubarb belonging to the family of Polygonaceae—are principal therapeutic materials in integrative medicine due to their rich quantities of bioactive compounds
however, their phytochemical and antioxidant properties, and anti-cancer activity is poorly investigated. Furthermore, the phytochemical characteristics of both species may be affected by their different geographical distribution and climatic variance. The current study aimed to compare RU with RC extracts in different polarity solvents (n-hexane, ethyl acetate, acetone, ethanol, and water) for their phytochemical contents including the total phenolic content (TPC), total anthraquinone content (TAC), total flavonoid content (TFC), antioxidant and free radical scavenging capacities, and anticancer ability on the HepG2 cell. Except for the n-hexane extract, all of the RU extracts had considerably higher TPCs than RC extracts, ranging from 8.39 to 11.16 mg gallic acid equivalent (GAE) per gram of dry weight, and the TPCs of each extract were also significantly correlated with their antioxidant capacities by ABTS, DPPH, and FRAP assays (p <
0.05). Moreover, there was no remarkable association between the antioxidant capacities and either TACs or TFCs in both the RU and RC extracts. Besides, high-performance liquid chromatography (HPLC) analysis revealed that both the RU and RC extracts contained chrysophanol, emodin, and physcion, and those bioactive compounds were relatively higher in the n-hexane solvent extracts. Additionally, we observed different levels of dose-dependent cytotoxic effects in all the extracts by cell viability assay. Notably, the ethanol extract of RU had a compelling cytotoxic effect with the lowest half-maximum inhibition concentration (IC50-171.94 ± 6.56 µg/mL at 48 h) among the RU extracts than the ethanol extract of RC. Interestingly, the ethanol extract of RU but not RC significantly induced apoptosis in the human liver cancer cell line, HepG2, with a distinct pattern in caspase-3 activation, resulting in increased PARP cleavage and DNA damage. In summary, Mongolian Rhubarb, RU, showed more phytochemical contents, as well as a higher antioxidant capacity and apoptotic effect to HepG2 than RC
thus, it can be exploited for the proper source of natural antioxidants and liver cancer treatment in further investigation.وصف الملف: application/pdf
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