المؤلفون: Qu C; State Key Lab of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, China; quchf@cicams.ac.cn wcavenee@ucsd.edu jiaoyuchen@126.com.; Immunology Department, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, China., Wang Y; State Key Lab of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, China.; Immunology Department, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, China., Wang P; State Key Lab of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, China., Chen K; State Key Lab of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, China.; Immunology Department, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, China., Wang M; Department of Clinical Laboratory, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, China., Zeng H; National Cancer Registration Office, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, P. R. China., Lu J; Qidong Liver Cancer Institute/Qidong People's Hospital, Qidong, 226200 Jiangsu Province, China., Song Q; State Key Lab of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, China., Diplas BH; The Preston Robert Tisch Brain Tumor Center at Duke, Duke University Medical Center, Durham, NC 27710., Tan D; Genetron Health (Beijing) Co. Ltd., 102206 Beijing, China., Fan C; Qidong Liver Cancer Institute/Qidong People's Hospital, Qidong, 226200 Jiangsu Province, China., Guo Q; Lingbi Center for Disease Control and Prevention, 234200 Anhui Province, China., Zhu Z; Department of Diagnostic Radiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, China., Yin H; State Key Lab of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, China., Jiang L; Genetron Health (Beijing) Co. Ltd., 102206 Beijing, China., Chen X; Genetron Health (Beijing) Co. Ltd., 102206 Beijing, China., Zhao H; Lingbi Center for Disease Control and Prevention, 234200 Anhui Province, China., He H; State Key Lab of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, China.; Immunology Department, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, China., Wang Y; Department of Ultrasonography, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, China., Li G; State Key Laboratory of Medical Molecular Biology, Department of Biochemistry and Center for Bioinformatics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, 100005 Beijing, China., Bi X; Department of Hepatobiliary Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, China., Zhao X; Department of Diagnostic Radiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, China., Chen T; Qidong Liver Cancer Institute/Qidong People's Hospital, Qidong, 226200 Jiangsu Province, China., Tang H; Qidong Liver Cancer Institute/Qidong People's Hospital, Qidong, 226200 Jiangsu Province, China., Lv C; Qidong Liver Cancer Institute/Qidong People's Hospital, Qidong, 226200 Jiangsu Province, China., Wang D; State Key Lab of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, China.; Immunology Department, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, China., Chen W; Office for Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, P. R. China., Zhou J; Department of Hepatobiliary Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, China., Zhao H; Department of Hepatobiliary Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, China., Cai J; Department of Hepatobiliary Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, China., Wang X; State Key Laboratory of Medical Molecular Biology, Department of Biochemistry and Center for Bioinformatics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, 100005 Beijing, China., Wang S; Genetron Health (Beijing) Co. Ltd., 102206 Beijing, China., Yan H; The Preston Robert Tisch Brain Tumor Center at Duke, Duke University Medical Center, Durham, NC 27710., Zeng YX; Department of Experimental Research, Sun Yat-sen University Cancer Center, State Key Laboratory Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China., Cavenee WK; Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093-0660 quchf@cicams.ac.cn wcavenee@ucsd.edu jiaoyuchen@126.com., Jiao Y; State Key Lab of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021 Beijing, China; quchf@cicams.ac.cn wcavenee@ucsd.edu jiaoyuchen@126.com.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Mar 26; Vol. 116 (13), pp. 6308-6312. Date of Electronic Publication: 2019 Mar 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Biomarkers, Tumor/*blood , Carcinoma, Hepatocellular/*diagnosis , Early Detection of Cancer/*methods , Hepatitis B Surface Antigens/*blood , Liquid Biopsy/*methods , Liver Neoplasms/*diagnosis, Carcinoma, Hepatocellular/blood ; Carcinoma, Hepatocellular/pathology ; Cell-Free Nucleic Acids ; Hepatitis B virus ; Hepatitis B, Chronic ; Humans ; Liver Neoplasms/blood ; Liver Neoplasms/pathology ; Sensitivity and Specificity ; Ultrasonography