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المؤلفون: May Yun Wang, Greg Poffenberger, Philipp E. Scherer, William L. Holland, Reshing Ye, Ruth E. Gimeno, Yiyi Zhang, Kyle W. Sloop, Derek C. Leonard, S. Kay McCorkle, Alexander M. Efanov, Roger H Unger, Yi Zhu, Alison Von Deylen, Alvin C. Powers, E. Danielle Dean, Shiuhwei Chen, Kamrul H. Chowdhury, Shangang Zhao, Zhuzhen Zhang, Xinxin Yu, Young Chul Lee, Ezekiel B. Quittner-Strom, Na Li, Amnon Schlegel
المصدر: Proceedings of the National Academy of Sciences of the United States of America
مصطلحات موضوعية: Blood Glucose, Medical Sciences, medicine.medical_treatment, Islets of Langerhans Transplantation, Gene Expression, Nod, chemistry.chemical_compound, Mice, Mice, Inbred NOD, Insulin-Secreting Cells, Receptors, Glucagon, Glucose homeostasis, Multidisciplinary, geography.geographical_feature_category, islet, diabetes, C-Peptide, C-peptide, Antibodies, Monoclonal, Organ Size, Biological Sciences, Islet, Treatment Outcome, hormones, hormone substitutes, and hormone antagonists, medicine.medical_specialty, insulin, Glucagon, Diabetes Mellitus, Experimental, Islets of Langerhans, Diabetes mellitus, Internal medicine, medicine, Animals, Humans, Hypoglycemic Agents, Cell Lineage, geography, business.industry, Insulin, medicine.disease, Endocrinology, Diabetes Mellitus, Type 1, chemistry, Glucagon-Secreting Cells, regeneration, Cell Transdifferentiation, business, Glucagon receptor
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d54743f23deaa0e45e756854cfbf90f
http://europepmc.org/articles/PMC7936318 -
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المؤلفون: Yi Zeng, Anna R. Kahkoska, Di Wen, Jinqiang Wang, John B. Buse, Valerie Wu, Jicheng Yu, Zejun Wang, Guojun Chen, Hongjun Li, Jayson Miedema, Zhen Gu
المصدر: Proc Natl Acad Sci U S A
مصطلحات موضوعية: Blood Glucose, Male, medicine.medical_specialty, Transdermal patch, medicine.medical_treatment, Drug Compounding, Transdermal Patch, 02 engineering and technology, Hypoglycemia, Insulin overdose, Glucagon, Streptozocin, Diabetes Mellitus, Experimental, Polymerization, 03 medical and health sciences, Mice, Drug Delivery Systems, Diabetes mellitus, Internal medicine, Medicine, Animals, Humans, Hypoglycemic Agents, Insulin, Acute hypoglycemia, 030304 developmental biology, 0303 health sciences, Multidisciplinary, business.industry, Insulin deficiency, 021001 nanoscience & nanotechnology, medicine.disease, Drug Combinations, Drug Liberation, Endocrinology, Diabetes Mellitus, Type 1, Solubility, Delayed-Action Preparations, Physical Sciences, Drug Overdose, 0210 nano-technology, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa292ab291b4de620023c0823c522990
https://europepmc.org/articles/PMC7703584/ -
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المؤلفون: Anna R. Kahkoska, Song Li, Julian P. Whitelegge, Zejun Wang, Jinqiang Wang, Zhen Gu, Jicheng Yu, Jun Fang, Yuqi Zhang, John B. Buse
المصدر: Proceedings of the National Academy of Sciences of the United States of America, vol 116, iss 22
مصطلحات موضوعية: Blood Glucose, insulin, medicine.medical_specialty, endocrine system, endocrine system diseases, medicine.medical_treatment, Glucose Transport Proteins, Facilitative, Insulin analog, Endogeny, Type 2 diabetes, Hypoglycemia, Autoimmune Disease, Diabetes Mellitus, Experimental, Experimental, Mice, glucose-responsive, Drug Delivery Systems, Internal medicine, Diabetes mellitus, Diabetes Mellitus, medicine, Animals, Hypoglycemic Agents, Insulin, Metabolic and endocrine, Multidisciplinary, diabetes, Chemistry, Prevention, Glucose transporter, nutritional and metabolic diseases, Facilitative, Biological Sciences, medicine.disease, insulin analog, carbohydrates (lipids), Endocrinology, Postprandial, 5.1 Pharmaceuticals, Hyperglycemia, drug delivery, Development of treatments and therapeutic interventions, Glucose Transport Proteins, hormones, hormone substitutes, and hormone antagonists
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cbb247169fa05060de62a841bcbde89
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المؤلفون: Michael Föller, Martina Feger, Lars-Oliver Klotz, Florian Lang, Berthold Hocher, Abul Fajol, Ludmilla Bär, Shufei Zeng
مصطلحات موضوعية: 0301 basic medicine, Fibroblast growth factor 23, Male, medicine.medical_specialty, Calcitriol, medicine.medical_treatment, Parathyroid hormone, 030209 endocrinology & metabolism, FOXO1, urologic and male genital diseases, Diabetes Mellitus, Experimental, 03 medical and health sciences, Mice, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, Pregnancy, Internal medicine, Cell Line, Tumor, medicine, Animals, Humans, Insulin, Protein kinase B, Klotho Proteins, Institut für Biochemie und Biologie, PI3K/AKT/mTOR pathway, Glucuronidase, Multidisciplinary, Chemistry, Growth factor, Biological Sciences, Rats, Fibroblast Growth Factors, stomatognathic diseases, Fibroblast Growth Factor-23, 030104 developmental biology, Endocrinology, Glucose, Gene Expression Regulation, Female, ddc:500, Proto-Oncogene Proteins c-akt, medicine.drug, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad51aae5f789d101474d5321716ee037
https://europepmc.org/articles/PMC5984514/ -
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المؤلفون: Babak Movahedi, Dusan Hanidziar, Nipun Goel, Terry B. Strom, Maria Koulmanda, Manoj Bhasin, Towia A. Libermann, Prabhakar Putheti, Zhigang Fan
مصطلحات موضوعية: Male, congenital, hereditary, and neonatal diseases and abnormalities, endocrine system, endocrine system diseases, Cell Survival, medicine.medical_treatment, Islets of Langerhans Transplantation, Inflammation, Biology, Diabetes Mellitus, Experimental, Islets of Langerhans, Mice, Immune system, Diabetes mellitus, medicine, Animals, Insulin, Type 1 diabetes, geography, Islet cell transplantation, Multidisciplinary, geography.geographical_feature_category, Biological Sciences, medicine.disease, Islet, Autotransplantation, Mice, Inbred C57BL, Diabetes Mellitus, Type 1, Treatment Outcome, Immune System, alpha 1-Antitrypsin, Immunology, medicine.symptom
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2b53f9389407bc8ec82fbb8abe48af4
https://europepmc.org/articles/PMC3458386/ -
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المؤلفون: Shawn C. Burgess, Young H Lee, May-Yun Wang, Xiaorong Fu, Maureen J. Charron, Roger H Unger, Eric D. Berglund, Xinxin Yu
مصطلحات موضوعية: Blood Glucose, medicine.medical_specialty, Chromatography, Gas, Diabetic ketoacidosis, Receptor expression, medicine.medical_treatment, Genetic Vectors, Immunoblotting, Enzyme-Linked Immunosorbent Assay, Biology, Real-Time Polymerase Chain Reaction, Glucagon, Mass Spectrometry, Adenoviridae, Diabetes Mellitus, Experimental, Impaired glucose tolerance, Mice, Internal medicine, Diabetes mellitus, medicine, Receptors, Glucagon, Animals, Insulin, Cyclic AMP Response Element-Binding Protein, DNA Primers, Mice, Knockout, Type 1 diabetes, Multidisciplinary, Biological Sciences, medicine.disease, Streptozotocin, Mice, Inbred C57BL, Endocrinology, Liver, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f474394139bcf683b64997e2f3017f42
https://europepmc.org/articles/PMC3443167/ -
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المؤلفون: Carey Backus, John M. Hayes, Adil Gasim, Masao Kakoki, Ruriko Grant, Hyung Suk Kim, Kelli A. Sullivan, Eva L. Feldman, J. Charles Jennette, Sarah B. Nossov, Kunjie Hua, Sang Su Oh, Oliver Smithies, Hirofumi Tomita
مصطلحات موضوعية: Male, medicine.medical_specialty, Receptor, Bradykinin B2, medicine.medical_treatment, Bradykinin, Biology, Receptor, Bradykinin B1, DNA, Mitochondrial, Nephropathy, Diabetes Mellitus, Experimental, Diabetic nephropathy, chemistry.chemical_compound, Mice, Diabetic Neuropathies, Bone Density, Internal medicine, Diabetes mellitus, medicine, Animals, Humans, Diabetic Nephropathies, Receptor, Mice, Knockout, Multidisciplinary, Insulin, Glomerulosclerosis, Biological Sciences, medicine.disease, Angiotensin II, Mice, Mutant Strains, Mice, Inbred C57BL, Endocrinology, Phenotype, chemistry, Osteoporosis
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a10952766d778e47c654ecd7b0dbd40
https://europepmc.org/articles/PMC2890475/ -
8Adenoviral transfer of HIF-1α enhances vascular responses to critical limb ischemia in diabetic mice
مصطلحات موضوعية: medicine.medical_specialty, Nitric Oxide Synthase Type III, Angiogenesis, medicine.medical_treatment, Ischemia, Neovascularization, Physiologic, Femoral artery, Revascularization, Adenoviridae, Diabetes Mellitus, Experimental, Mice, Internal medicine, medicine.artery, Diabetes mellitus, medicine, Limb perfusion, Animals, Humans, Muscle, Skeletal, Ligation, Multidisciplinary, business.industry, Extremities, Critical limb ischemia, Anatomy, Genetic Therapy, Biological Sciences, medicine.disease, Hypoxia-Inducible Factor 1, alpha Subunit, Immunohistochemistry, Femoral Artery, Cardiology, medicine.symptom, business, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::242ac93726eb6152b417e299b17dbdde
https://europepmc.org/articles/PMC2774037/ -
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المؤلفون: Marco J Herold, Jost Seibler, Jens van den Brandt, Holger M. Reichardt
مصطلحات موضوعية: medicine.medical_treatment, Transgene, Virus Integration, Genetic Vectors, Cell Line, Diabetes Mellitus, Experimental, Small hairpin RNA, RNA interference, medicine, Gene Knockdown Techniques, Gene silencing, Animals, Humans, Insulin, Gene Silencing, DNA Primers, Multidisciplinary, biology, Base Sequence, Lentivirus, Biological Sciences, Glucose Tolerance Test, Molecular biology, Cell biology, Rats, Insulin receptor, Diabetes Mellitus, Type 2, biology.protein, RNA, Viral, Signal transduction, Rats, Transgenic, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ace1c800069d90279d68458aae235790
https://europepmc.org/articles/PMC2587564/ -
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المؤلفون: Evan R. Simpson, Franck Mauvais-Jarvis, Min Hu, Christina S. Ortega, Kenneth S. Korach, Khoi Chu, Cédric Le May, Ming-Jer Tsai
المساهمون: unité de recherche de l'institut du thorax UMR1087 UMR6291 (ITX), Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2006, 103 (24), pp.9232-9237. ⟨10.1073/pnas.0602956103⟩مصطلحات موضوعية: Male, medicine.medical_treatment, Apoptosis, medicine.disease_cause, Mice, Random Allocation, 0302 clinical medicine, Insulin-Secreting Cells, Insulin, Aromatase, ComputingMilieux_MISCELLANEOUS, Mice, Knockout, 0303 health sciences, Multidisciplinary, Estradiol, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, Biological Sciences, medicine.anatomical_structure, Female, hormones, hormone substitutes, and hormone antagonists, medicine.drug, medicine.medical_specialty, medicine.drug_class, Cell Survival, 030209 endocrinology & metabolism, Biology, Diabetes Mellitus, Experimental, 03 medical and health sciences, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Internal medicine, Diabetes mellitus, medicine, [SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO], Animals, Humans, 030304 developmental biology, Cell Proliferation, Pancreatic islets, Estrogen Receptor alpha, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, medicine.disease, Streptozotocin, Endocrinology, Diabetes Mellitus, Type 1, Estrogen, biology.protein, Estrogen receptor alpha, Oxidative stress
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c7bf3448780747e8bfc5257e5dca249
https://europepmc.org/articles/PMC1482595/