المؤلفون: Cazet AS; Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; The Kinghorn Cancer Centre, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Darlinghurst, NSW, 2010, Australia., Hui MN; Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; The Kinghorn Cancer Centre, Darlinghurst, NSW, 2010, Australia.; The Chris O' Brien Lifehouse, Camperdown, NSW, 2050, Australia.; Royal Prince Alfred Hospital, Camperdown, NSW, 2050, Australia., Elsworth BL; MRC Integrative Epidemiology Unit, University of Bristol, Oakfield House, Bristol, BS8 2BN, UK., Wu SZ; Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; The Kinghorn Cancer Centre, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Darlinghurst, NSW, 2010, Australia., Roden D; Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; The Kinghorn Cancer Centre, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Darlinghurst, NSW, 2010, Australia., Chan CL; Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; The Kinghorn Cancer Centre, Darlinghurst, NSW, 2010, Australia., Skhinas JN; Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; The Kinghorn Cancer Centre, Darlinghurst, NSW, 2010, Australia., Collot R; Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; The Kinghorn Cancer Centre, Darlinghurst, NSW, 2010, Australia., Yang J; Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; The Kinghorn Cancer Centre, Darlinghurst, NSW, 2010, Australia., Harvey K; Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; The Kinghorn Cancer Centre, Darlinghurst, NSW, 2010, Australia., Johan MZ; Centre for Cancer Biology, SA Pathology and the University of South Australia, Adelaide, SA, 5000, Australia.; Faculty of Health Sciences, School of Medicine, University of Adelaide, Adelaide, SA, 5000, Australia., Cooper C; Pathology Queensland and School of Medicine, University of Queensland, St Lucia, QLD, 4006, Australia., Nair R; Rajiv Gandhi Centre for Biotechnology, Thycaud Post, Poojappura, Thiruvananthapuram, Kerala, 695014, India., Herrmann D; Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; The Kinghorn Cancer Centre, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Darlinghurst, NSW, 2010, Australia., McFarland A; Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; The Kinghorn Cancer Centre, Darlinghurst, NSW, 2010, Australia., Deng N; Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; The Kinghorn Cancer Centre, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Darlinghurst, NSW, 2010, Australia., Ruiz-Borrego M; Department of Medical Oncology, Hospital Universitario Virgen del Rocío, 41013, Sevilla, Spain., Rojo F; Department of Pathology, Hospital Universitario Fundación Jiménez Díaz, 28040, Madrid, Spain., Trigo JM; Department of Medical Oncology, Hospital Clínico Universitario Virgen de la Victoria, IBIMA, 29010, Málaga, Spain., Bezares S; GEICAM, Spanish Breast Cancer Group, Madrid, 28703, Spain., Caballero R; GEICAM, Spanish Breast Cancer Group, Madrid, 28703, Spain., Lim E; Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; The Kinghorn Cancer Centre, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Darlinghurst, NSW, 2010, Australia.; St Vincent's Hospital, 2010, Darlinghurst, NSW, Australia., Timpson P; Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; The Kinghorn Cancer Centre, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Darlinghurst, NSW, 2010, Australia., O'Toole S; Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; The Kinghorn Cancer Centre, Darlinghurst, NSW, 2010, Australia.; Royal Prince Alfred Hospital, Camperdown, NSW, 2050, Australia., Watkins DN; Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; The Kinghorn Cancer Centre, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Darlinghurst, NSW, 2010, Australia.; St Vincent's Hospital, 2010, Darlinghurst, NSW, Australia., Cox TR; Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; The Kinghorn Cancer Centre, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Darlinghurst, NSW, 2010, Australia., Samuel MS; Centre for Cancer Biology, SA Pathology and the University of South Australia, Adelaide, SA, 5000, Australia.; Faculty of Health Sciences, School of Medicine, University of Adelaide, Adelaide, SA, 5000, Australia., Martín M; Department of Medical Oncology, Instituto de Investigación Sanitaria Gregorio Marañón, Universidad Complutense, Centro de Investigación Biomédica en Red de Oncología, CIBERONC-ISCIII, 28040, Madrid, Spain., Swarbrick A; Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia. a.swarbrick@garvan.org.au.; The Kinghorn Cancer Centre, Darlinghurst, NSW, 2010, Australia. a.swarbrick@garvan.org.au.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Darlinghurst, NSW, 2010, Australia. a.swarbrick@garvan.org.au.

المصدر: Nature communications [Nat Commun] 2018 Jul 24; Vol. 9 (1), pp. 2897. Date of Electronic Publication: 2018 Jul 24.

نوع المنشور: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Combined Chemotherapy Protocols/*therapeutic use , Drug Resistance, Neoplasm/*drug effects , Neoplastic Stem Cells/*drug effects , Triple Negative Breast Neoplasms/*drug therapy, Adult ; Aged ; Anilides/administration & dosage ; Animals ; Biphenyl Compounds/administration & dosage ; Cell Line, Tumor ; Docetaxel/administration & dosage ; Female ; Humans ; Mice, Inbred NOD ; Mice, Knockout ; Mice, SCID ; Middle Aged ; Neoplastic Stem Cells/metabolism ; Pyridines/administration & dosage ; Treatment Outcome ; Triple Negative Breast Neoplasms/genetics ; Triple Negative Breast Neoplasms/metabolism ; Xenograft Model Antitumor Assays