المؤلفون: Coignard J; Genetic Epidemiology of Cancer team, Inserm, U900, Paris, France.; Institut Curie Paris, Paris, France.; Mines ParisTech Fontainebleau, Paris, France.; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; PSL University Paris, Paris, France.; Paris Sud University, Orsay, France., Lush M; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Beesley J; Department of Genetics and Computational Biology QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., O'Mara TA; Department of Genetics and Computational Biology QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Dennis J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Tyrer JP; Centre for Cancer Genetic Epidemiology, Department of Oncology University of Cambridge, Cambridge, UK., Barnes DR; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., McGuffog L; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Leslie G; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Bolla MK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Adank MA; Family Cancer Clinic, The Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands., Agata S; Immunology and Molecular Oncology, Unit Veneto Institute of Oncology IOV - IRCCS, Padua, Italy., Ahearn T; Division of Cancer Epidemiology and Genetics National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA., Aittomäki K; Department of Clinical Genetics, Helsinki University Hospital University of Helsinki, Helsinki, Finland., Andrulis IL; Fred A. Litwin Center for Cancer Genetics Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, ON, Canada.; Department of Molecular Genetics University of Toronto, Toronto, ON, Canada., Anton-Culver H; Department of Epidemiology, Genetic Epidemiology Research Institute University of California Irvine, Irvine, CA, USA., Arndt V; Division of Clinical Epidemiology and Aging Research German Cancer Research Center (DKFZ), Heidelberg, Germany., Arnold N; Department of Gynaecology and Obstetrics University Hospital of Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel, Kiel, Germany.; Institute of Clinical Molecular Biology University Hospital of Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel, Kiel, Germany., Aronson KJ; Department of Public Health Sciences, and Cancer Research Institute Queen's University, Kingston, ON, Canada., Arun BK; Department of Breast Medical Oncology University of Texas MD Anderson Cancer Center, Houston, TX, USA., Augustinsson A; Department of Cancer Epidemiology, Clinical Sciences Lund University, Lund, 22242, Sweden., Azzollini J; Unit of Medical Genetics, Department of Medical Oncology and Hematology Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy., Barrowdale D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Baynes C; Centre for Cancer Genetic Epidemiology, Department of Oncology University of Cambridge, Cambridge, UK., Becher H; Institute for Medical Biometrics and Epidemiology University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Bermisheva M; Institute of Biochemistry and Genetics Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia., Bernstein L; Department of Population Sciences Beckman Research Institute of City of Hope, Duarte, CA, USA., Białkowska K; Department of Genetics and Pathology Pomeranian Medical University Szczecin, Szczecin, Poland., Blomqvist C; Department of Oncology, Helsinki University Hospital University of Helsinki, Helsinki, Finland.; Department of Oncology Örebro University Hospital, Örebro, Sweden., Bojesen SE; Copenhagen General Population Study, Herlev and Gentofte Hospital Copenhagen University Hospital, Herlev, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital Copenhagen University Hospital, Herlev, Denmark.; Faculty of Health and Medical Sciences University of Copenhagen, Copenhagen, Denmark., Bonanni B; Division of Cancer Prevention and Genetics IEO, European Institute of Oncology IRCCS, Milan, Italy., Borg A; Department of Oncology Lund University and Skåne University Hospital, Lund, Sweden., Brauch H; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.; iFIT-Cluster of Excellence University of Tübingen, Tübingen, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany., Brenner H; Division of Clinical Epidemiology and Aging Research German Cancer Research Center (DKFZ), Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Burwinkel B; Molecular Epidemiology Group, C080 German Cancer Research Center (DKFZ), Heidelberg, Germany.; Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg University of Heidelberg, Heidelberg, Germany., Buys SS; Department of Medicine Huntsman Cancer Institute, Salt Lake City, UT, USA., Caldés T; Molecular Oncology Laboratory CIBERONC, Hospital Clinico San Carlos, IdISSC (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos), Madrid, Spain., Caligo MA; SOD Genetica Molecolare University Hospital, Pisa, Italy., Campa D; Department of Biology University of Pisa, Pisa, Italy.; Division of Cancer Epidemiology German Cancer Research Center (DKFZ), Heidelberg, Germany., Carter BD; Behavioral and Epidemiology Research Group American Cancer Society Atlanta, Atlanta, GA, USA., Castelao JE; Oncology and Genetics Unit Instituto de Investigacion Sanitaria Galicia Sur (IISGS), Xerencia de Xestion Integrada de Vigo-SERGAS, Vigo, Spain., Chang-Claude J; Division of Cancer Epidemiology German Cancer Research Center (DKFZ), Heidelberg, Germany.; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH) University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Chanock SJ; Division of Cancer Epidemiology and Genetics National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA., Chung WK; Departments of Pediatrics and Medicine, Columbia University, New York, NY, USA., Claes KBM; Centre for Medical Genetics Ghent University, Gent, Belgium., Clarke CL; Westmead Institute for Medical Research University of Sydney, Sydney, NSW, Australia., Collée JM; Department of Clinical Genetics Erasmus University Medical Center, Rotterdam, The Netherlands., Conroy DM; Centre for Cancer Genetic Epidemiology, Department of Oncology University of Cambridge, Cambridge, UK., Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Daly MB; Department of Clinical Genetics Fox Chase Cancer Center Philadelphia, Philadelphia, PA, USA., Devilee P; Department of Pathology Leiden University Medical Center, Leiden, The Netherlands.; Department of Human Genetics Leiden University Medical Center, Leiden, The Netherlands., Diez O; Oncogenetics Group Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.; Clinical and Molecular Genetics Area University Hospital Vall d'Hebron, Barcelona, Spain., Ding YC; Department of Population Sciences Beckman Research Institute of City of Hope, Duarte, CA, USA., Domchek SM; Basser Center for BRCA, Abramson Cancer Center University of Pennsylvania, Philadelphia, PA, USA., Dörk T; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Dos-Santos-Silva I; Department of Non-Communicable Disease Epidemiology London School of Hygiene and Tropical Medicine, London, UK., Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology University of Cambridge, Cambridge, UK., Dwek M; School of Life Sciences University of Westminster, London, UK., Eccles DM; Faculty of Medicine University of Southampton, Southampton, UK., Eliassen AH; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Epidemiology Harvard TH Chan School of Public Health, Boston, MA, USA., Engel C; Institute for Medical Informatics, Statistics and Epidemiology University of Leipzig, Leipzig, Germany., Eriksson M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Evans DG; Genomic Medicine, Division of Evolution and Genomic Sciences The University of Manchester, Manchester Academic Health Science Centre, Manchester Universities Foundation Trust, St Mary's Hospital, Manchester, UK.; Genomic Medicine, North West Genomics hub Manchester Academic Health Science Centre, Manchester Universities Foundation Trust, St Mary's Hospital, Manchester, UK., Fasching PA; David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology University of California at Los Angeles, Los Angeles, CA, USA.; Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN University Hospital Erlangen, Friedrich-Alexander-University, Erlangen-Nuremberg, Erlangen, Germany., Flyger H; Department of Breast Surgery, Herlev and Gentofte Hospital Copenhagen University Hospital, Herlev, Denmark., Fostira F; Molecular Diagnostics Laboratory, INRASTES National Centre for Scientific Research íDemokritosí, Athens, Greece., Friedman E; The Susanne Levy Gertner Oncogenetics Unit Chaim Sheba Medical Center, Ramat Gan, Israel.; Sackler Faculty of Medicine Tel Aviv University, Ramat Aviv, Israel., Fritschi L; School of Public Health Curtin University, Perth, Western Australia, Australia., Frost D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Gago-Dominguez M; Genomic Medicine Group, Galician Foundation of Genomic Medicine Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain.; Moores Cancer Center University of California, San Diego La Jolla, CA, USA., Gapstur SM; Behavioral and Epidemiology Research Group American Cancer Society Atlanta, Atlanta, GA, USA., Garber J; Division of Cancer Genetics and Prevention, Dana-Farber Cancer Institute, Boston, MA, USA., Garcia-Barberan V; Medical Oncology Department, Hospital Clínico San Carlos Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain., García-Closas M; Division of Cancer Epidemiology and Genetics National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA., García-Sáenz JA; Medical Oncology Department, Hospital Clínico San Carlos Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain., Gaudet MM; Behavioral and Epidemiology Research Group American Cancer Society Atlanta, Atlanta, GA, USA., Gayther SA; Center for Bioinformatics and Functional Genomics and the Cedars Sinai Genomics Core Cedars-Sinai Medical Center, Los Angeles, CA, USA., Gehrig A; Department of Human Genetics University Würzburg, Würzburg, Germany., Georgoulias V; Department of Medical Oncology University Hospital of Heraklion, Heraklion, Greece., Giles GG; Cancer Epidemiology Division Cancer Council Victoria, Melbourne, VIC, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health Monash University, Clayton, VIC, Australia., Godwin AK; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS, USA., Goldberg MS; Department of Medicine, McGill University, Montréal, QC, Canada.; Division of Clinical Epidemiology, Royal Victoria Hospital McGill University Montréal, Montréal, QC, Canada., Goldgar DE; Huntsman Cancer Institute and Department of Dermatology, University of Utah School of Medicine, Salt Lake City, UT, USA., González-Neira A; Human Cancer Genetics Programme Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Greene MH; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics National Cancer Institute, Bethesda, MD, USA., Guénel P; Cancer & Environment Group, Center for Research in Epidemiology and Population Health (CESP) INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France., Haeberle L; Department of Gynaecology and Obstetrics, University Hospital Erlangen Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany., Hahnen E; Center for Hereditary Breast and Ovarian Cancer Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO) Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Haiman CA; Department of Preventive Medicine, Keck School of Medicine University of Southern California, Los Angeles, CA, USA., Håkansson N; Department of Oncology, Södersjukhuset, Stockholm, Sweden., Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Department of Oncology, Södersjukhuset, Stockholm, Sweden., Hamann U; Molecular Genetics of Breast Cancer German Cancer Research Center (DKFZ), Heidelberg, Germany., Harrington PA; Centre for Cancer Genetic Epidemiology, Department of Oncology University of Cambridge, Cambridge, UK., Hart SN; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., He W; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Hogervorst FBL; Family Cancer Clinic, The Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands., Hollestelle A; Department of Medical Oncology, Family Cancer Clinic Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia., Horcasitas DJ; New Mexico Oncology Hematology Consultants, University of New Mexico, Albuquerque, NM, USA., Hulick PJ; Center for Medical Genetics NorthShore University HealthSystem, Evanston, IL, USA.; The University of Chicago Pritzker School of Medicine Chicago, Chicago, IL, USA., Hunter DJ; Department of Epidemiology Harvard TH Chan School of Public Health, Boston, MA, USA.; Program in Genetic Epidemiology and Statistical Genetics Harvard TH Chan School of Public Health Boston, Boston, MA, USA.; Nuffield Department of Population Health University of Oxford, Oxford, UK., Imyanitov EN; NN Petrov Institute of Oncology, St. Petersburg, Russia., Jager A; Department of Medical Oncology, Family Cancer Clinic Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Jakubowska A; Department of Genetics and Pathology Pomeranian Medical University Szczecin, Szczecin, Poland.; Independent Laboratory of Molecular Biology and Genetic Diagnostics Pomeranian Medical University, Szczecin, Poland., James PA; Sir Peter MacCallum Department of Oncology The University of Melbourne, Melbourne, VIC, Australia.; Parkville Familial Cancer Centre Peter MacCallum Cancer Center, Melbourne, VIC, Australia., Jensen UB; Department of Clinical Genetics Aarhus, University Hospital, Aarhus, Denmark., John EM; Department of Medicine, Division of Oncology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, USA., Jones ME; Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, USA., Kaaks R; Division of Cancer Epidemiology German Cancer Research Center (DKFZ), Heidelberg, Germany., Kapoor PM; Division of Cancer Epidemiology German Cancer Research Center (DKFZ), Heidelberg, Germany.; Division of Genetics and Epidemiology The Institute of Cancer Research, London, UK., Karlan BY; Faculty of Medicine University of Heidelberg, Heidelberg, Germany.; David Geffen School of Medicine, Department of Obstetrics and Gynecology University of California at Los Angeles, Los Angeles, CA, USA., Keeman R; Womenís Cancer Program at the Samuel Oschin Comprehensive Cancer Institute Cedars-Sinai Medical Center, Los Angeles, CA, USA., Khusnutdinova E; Institute of Biochemistry and Genetics Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia.; Division of Molecular Pathology The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands., Kiiski JI; Department of Genetics and Fundamental Medicine Bashkir State Medical University, Ufa, Russia., Ko YD; Department of Obstetrics and Gynecology, Helsinki University Hospital University of Helsinki, Helsinki, Finland., Kosma VM; Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH Johanniter Krankenhaus, Bonn, Germany.; Translational Cancer Research Area University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine University of Eastern Finland, Kuopio, Finland., Kraft P; Department of Epidemiology Harvard TH Chan School of Public Health, Boston, MA, USA.; Program in Genetic Epidemiology and Statistical Genetics Harvard TH Chan School of Public Health Boston, Boston, MA, USA., Kurian AW; Department of Medicine, Division of Oncology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, USA., Laitman Y; The Susanne Levy Gertner Oncogenetics Unit Chaim Sheba Medical Center, Ramat Gan, Israel., Lambrechts D; VIB Center for Cancer Biology, Leuven, Belgium.; Laboratory for Translational Genetics, Department of Human Genetics University of Leuven, Leuven, Belgium., Le Marchand L; Epidemiology Program University of Hawaii Cancer Center, Honolulu, HI, USA., Lester J; Faculty of Medicine University of Heidelberg, Heidelberg, Germany.; David Geffen School of Medicine, Department of Obstetrics and Gynecology University of California at Los Angeles, Los Angeles, CA, USA., Lesueur F; Genetic Epidemiology of Cancer team, Inserm, U900, Paris, France.; Institut Curie Paris, Paris, France.; Mines ParisTech Fontainebleau, Paris, France.; PSL University Paris, Paris, France., Lindstrom T; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Lopez-Fernández A; High Risk and Cancer Prevention Group Vall d'Hebron Institute of Oncology, Barcelona, Spain., Loud JT; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics National Cancer Institute, Bethesda, MD, USA., Luccarini C; Centre for Cancer Genetic Epidemiology, Department of Oncology University of Cambridge, Cambridge, UK., Mannermaa A; Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH Johanniter Krankenhaus, Bonn, Germany.; Translational Cancer Research Area University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine University of Eastern Finland, Kuopio, Finland., Manoukian S; Unit of Medical Genetics, Department of Medical Oncology and Hematology Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy., Margolin S; Department of Oncology, Södersjukhuset, Stockholm, Sweden.; Department of Clinical Science and Education, Södersjukhuset Karolinska Institutet, Stockholm, Sweden., Martens JWM; Department of Medical Oncology, Family Cancer Clinic Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Mebirouk N; Genetic Epidemiology of Cancer team, Inserm, U900, Paris, France.; Institut Curie Paris, Paris, France.; Mines ParisTech Fontainebleau, Paris, France.; PSL University Paris, Paris, France., Meindl A; Department of Gynecology and Obstetrics University of Munich, Campus Grosshadern, Munich, Germany., Miller A; NRG Oncology, Statistics and Data Management Center Roswell Park Cancer Institute, Buffalo, NY, USA., Milne RL; Cancer Epidemiology Division Cancer Council Victoria, Melbourne, VIC, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health Monash University, Clayton, VIC, Australia., Montagna M; Immunology and Molecular Oncology, Unit Veneto Institute of Oncology IOV - IRCCS, Padua, Italy., Nathanson KL; Basser Center for BRCA, Abramson Cancer Center University of Pennsylvania, Philadelphia, PA, USA., Neuhausen SL; Department of Population Sciences Beckman Research Institute of City of Hope, Duarte, CA, USA., Nevanlinna H; Department of Genetics and Fundamental Medicine Bashkir State Medical University, Ufa, Russia., Nielsen FC; Center for Genomic Medicine Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., O'Brien KM; Epidemiology Branch National Institute of Environmental Health Sciences, NIH Research Triangle Park, Durham, NC, USA., Olopade OI; Center for Clinical Cancer Genetics The University of Chicago, Chicago, IL, USA., Olson JE; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Olsson H; Department of Cancer Epidemiology, Clinical Sciences Lund University, Lund, 22242, Sweden., Osorio A; Human Cancer Genetics Programme Spanish National Cancer Research Centre (CNIO), Madrid, Spain.; Centro de Investigación en Red de Enfermedades Raras (CIBERER), Madrid, Spain., Ottini L; Department of Molecular Medicine University La Sapienza, Rome, Italy., Park-Simon TW; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Parsons MT; Department of Genetics and Computational Biology QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Pedersen IS; Molecular Diagnostics Aalborg University Hospital, Aalborg, Denmark.; Clinical Cancer Research Center Aalborg University Hospital, Aalborg, Denmark.; Department of Clinical Medicine Aalborg University, Aalborg, Denmark., Peshkin B; Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., Peterlongo P; Genome Diagnostics Program IFOM - the FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan, Italy., Peto J; Department of Non-Communicable Disease Epidemiology London School of Hygiene and Tropical Medicine, London, UK., Pharoah PDP; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology University of Cambridge, Cambridge, UK., Phillips KA; Department of Genetics and Computational Biology QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia.; Sir Peter MacCallum Department of Oncology The University of Melbourne, Melbourne, VIC, Australia., Polley EC; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Poppe B; Centre for Medical Genetics Ghent University, Gent, Belgium., Presneau N; School of Life Sciences University of Westminster, London, UK., Pujana MA; Translational Research Laboratory IDIBELL (Bellvitge Biomedical Research Institute), Catalan Institute of Oncology, CIBERONC, Barcelona, Spain., Punie K; Leuven Multidisciplinary Breast Center, Department of Oncology Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium., Radice P; Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan, Italy., Rantala J; Clinical Genetics Karolinska Institutet, Stockholm, Sweden., Rashid MU; Molecular Genetics of Breast Cancer German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Basic Sciences Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH & RC), Lahore, Pakistan., Rennert G; Clalit National Cancer Control Center Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel., Rennert HS; Clalit National Cancer Control Center Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel., Robson M; Clinical Genetics Service, Department of Medicine Memorial Sloan-Kettering Cancer Center, New York, NY, USA., Romero A; Medical Oncology Department Hospital Universitario Puerta de Hierro, Madrid, Spain., Rossing M; Center for Genomic Medicine Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Saloustros E; Department of Oncology University Hospital of Larissa, Larissa, Greece., Sandler DP; Epidemiology Branch National Institute of Environmental Health Sciences, NIH Research Triangle Park, Durham, NC, USA., Santella R; Department of Epidemiology, Mailman School of Public Health Columbia University, New York, NY, USA., Scheuner MT; Cancer Genetics and Prevention Program University of California San Francisco, San Francisco, CA, USA., Schmidt MK; Womenís Cancer Program at the Samuel Oschin Comprehensive Cancer Institute Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Division of Psychosocial Research and Epidemiology The Netherlands Cancer Institute - Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands., Schmidt G; Institute of Human Genetics Hannover Medical School, Hannover, Germany., Scott C; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Sharma P; Department of Internal Medicine, Division of Medical Oncology University of Kansas Medical Center, Westwood, KS, USA., Soucy P; Genomics Center, Centre Hospitalier Universitaire de Québec - Université Laval Research Center, Québec City, QC, Canada., Southey MC; Precision Medicine, School of Clinical Sciences at Monash Health Monash University, Clayton, VIC, Australia.; Department of Clinical Pathology The University of Melbourne, Melbourne, VIC, Australia., Spinelli JJ; Population Oncology BC Cancer, Vancouver, BC, Canada.; School of Population and Public Health University of British Columbia, Vancouver, BC, Canada., Steinsnyder Z; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics Memorial Sloan-Kettering Cancer Center, New York, NY, USA., Stone J; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia.; The Curtin UWA Centre for Genetic Origins of Health and Disease Curtin University and University of Western Australia, Perth, Western Australia, Australia., Stoppa-Lyonnet D; Service de Génétique Institut Curie, Paris, France.; Department of Tumour Biology INSERM U830, Paris, France.; Université Paris Descartes, Paris, France., Swerdlow A; Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, USA.; Division of Breast Cancer Research Institute of Cancer Research, London, UK., Tamimi RM; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Epidemiology Harvard TH Chan School of Public Health, Boston, MA, USA.; Program in Genetic Epidemiology and Statistical Genetics Harvard TH Chan School of Public Health Boston, Boston, MA, USA., Tapper WJ; Faculty of Medicine University of Southampton, Southampton, UK., Taylor JA; Epidemiology Branch National Institute of Environmental Health Sciences, NIH Research Triangle Park, Durham, NC, USA.; Epigenetic and Stem Cell Biology Laboratory National Institute of Environmental Health Sciences, NIH Research Triangle Park, Triangle Park, NC, USA., Terry MB; Department of Epidemiology, Mailman School of Public Health Columbia University, New York, NY, USA., Teulé A; Hereditary Cancer Program ONCOBELL-IDIBELL-IDIBGI-IGTP, Catalan Institute of Oncology, CIBERONC, Barcelona, Spain., Thull DL; Department of Medicine Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Tischkowitz M; Program in Cancer Genetics, Departments of Human Genetics and Oncology McGill University, Montréal, QC, Canada.; Department of Medical Genetics, National Institute for Health Research Cambridge Biomedical Research Center, University of Cambridge, Cambridge, UK., Toland AE; Department of Cancer Biology and Genetics The Ohio State University, Columbus, OH, USA., Torres D; Molecular Genetics of Breast Cancer German Cancer Research Center (DKFZ), Heidelberg, Germany.; Institute of Human Genetics Pontificia Universidad Javeriana, Bogota, Colombia., Trainer AH; Parkville Familial Cancer Centre Peter MacCallum Cancer Center, Melbourne, VIC, Australia.; Department of medicine University Of Melbourne, Melbourne, VIC, Australia., Truong T; Cancer & Environment Group, Center for Research in Epidemiology and Population Health (CESP) INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France., Tung N; Department of Medical Oncology Beth Israel Deaconess Medical Center, Boston, MA, USA., Vachon CM; Department of Health Science Research, Division of Epidemiology Mayo Clinic, Rochester, MN, USA., Vega A; Fundación Pública Galega Medicina Xenómica-SERGAS, Instituto de Investigación Sanitaria Santiago de Compostela (IDIS); CIBERER, Santiago de Compostela, Spain., Vijai J; Clinical Genetics Service, Department of Medicine Memorial Sloan-Kettering Cancer Center, New York, NY, USA.; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics Memorial Sloan-Kettering Cancer Center, New York, NY, USA., Wang Q; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Wappenschmidt B; Center for Hereditary Breast and Ovarian Cancer Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO) Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Weinberg CR; Biostatistics and Computational Biology Branch National Institute of Environmental Health Sciences, NIH Research Triangle Park, Triangle Park, NC, USA., Weitzel JN; Clinical Cancer Genomics City of Hope, Duarte, CA, USA., Wendt C; Department of Clinical Science and Education, Södersjukhuset Karolinska Institutet, Stockholm, Sweden., Wolk A; Institute of Environmental Medicine Karolinska Institutet, Stockholm, Sweden.; Department of Surgical Sciences Uppsala University, Uppsala, Sweden., Yadav S; Department of Oncology Mayo Clinic, Rochester, MN, USA., Yang XR; Division of Cancer Epidemiology and Genetics National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA., Yannoukakos D; Molecular Diagnostics Laboratory, INRASTES National Centre for Scientific Research íDemokritosí, Athens, Greece., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center Vanderbilt University School of Medicine, Nashville, TN, USA., Ziogas A; Department of Epidemiology, Genetic Epidemiology Research Institute University of California Irvine, Irvine, CA, USA., Zorn KK; Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Park SK; Department of Preventive Medicine Seoul National University College of Medicine, Seoul, Korea.; Department of Biomedical Sciences Seoul National University Graduate School, Seoul, Korea.; Cancer Research Institute Seoul National University, Seoul, Korea., Thomassen M; Department of Clinical Genetics Odense University Hospital, Odence C, Denmark., Offit K; Clinical Genetics Service, Department of Medicine Memorial Sloan-Kettering Cancer Center, New York, NY, USA.; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics Memorial Sloan-Kettering Cancer Center, New York, NY, USA., Schmutzler RK; Center for Hereditary Breast and Ovarian Cancer Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO) Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Couch FJ; Department of Laboratory Medicine and Pathology Mayo Clinic, Rochester, MN, USA., Simard J; Department of Epidemiology, Genetic Epidemiology Research Institute University of California Irvine, Irvine, CA, USA., Chenevix-Trench G; Department of Genetics and Computational Biology QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology University of Cambridge, Cambridge, UK., Andrieu N; Genetic Epidemiology of Cancer team, Inserm, U900, Paris, France. nadine.andrieu@curie.fr.; Institut Curie Paris, Paris, France. nadine.andrieu@curie.fr.; Mines ParisTech Fontainebleau, Paris, France. nadine.andrieu@curie.fr.; PSL University Paris, Paris, France. nadine.andrieu@curie.fr., Antoniou AC; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. aca20@medschl.cam.ac.uk.

مؤلفون مشاركون: GEMO Study Collaborators, EMBRACE Collaborators, KConFab Investigators, HEBON Investigators, ABCTB Investigators

المصدر: Nature communications [Nat Commun] 2021 May 14; Vol. 12 (1), pp. 2986. Date of Electronic Publication: 2021 May 14.

نوع المنشور: Published Erratum

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Coignard J; Genetic Epidemiology of Cancer team, Inserm, U900, Paris, France.; Institut Curie Paris, Paris, France.; Mines ParisTech Fontainebleau, Paris, France.; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; PSL University Paris, Paris, France.; Paris Sud University, Orsay, France., Lush M; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Beesley J; Department of Genetics and Computational Biology QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., O'Mara TA; Department of Genetics and Computational Biology QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Dennis J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Tyrer JP; Centre for Cancer Genetic Epidemiology, Department of Oncology University of Cambridge, Cambridge, UK., Barnes DR; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., McGuffog L; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Leslie G; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Bolla MK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Adank MA; Family Cancer Clinic, The Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands., Agata S; Immunology and Molecular Oncology, Unit Veneto Institute of Oncology IOV - IRCCS, Padua, Italy., Ahearn T; Division of Cancer Epidemiology and Genetics National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA., Aittomäki K; Department of Clinical Genetics, Helsinki University Hospital University of Helsinki, Helsinki, Finland., Andrulis IL; Fred A. Litwin Center for Cancer Genetics Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, ON, Canada.; Department of Molecular Genetics University of Toronto, Toronto, ON, Canada., Anton-Culver H; Department of Epidemiology, Genetic Epidemiology Research Institute University of California Irvine, Irvine, CA, USA., Arndt V; Division of Clinical Epidemiology and Aging Research German Cancer Research Center (DKFZ), Heidelberg, Germany., Arnold N; Department of Gynaecology and Obstetrics University Hospital of Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel, Kiel, Germany.; Institute of Clinical Molecular Biology University Hospital of Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel, Kiel, Germany., Aronson KJ; Department of Public Health Sciences, and Cancer Research Institute Queen's University, Kingston, ON, Canada., Arun BK; Department of Breast Medical Oncology University of Texas MD Anderson Cancer Center, Houston, TX, USA., Augustinsson A; Department of Cancer Epidemiology, Clinical Sciences Lund University, Lund, 22242, Sweden., Azzollini J; Unit of Medical Genetics, Department of Medical Oncology and Hematology Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy., Barrowdale D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Baynes C; Centre for Cancer Genetic Epidemiology, Department of Oncology University of Cambridge, Cambridge, UK., Becher H; Institute for Medical Biometrics and Epidemiology University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Bermisheva M; Institute of Biochemistry and Genetics Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia., Bernstein L; Department of Population Sciences Beckman Research Institute of City of Hope, Duarte, CA, USA., Białkowska K; Department of Genetics and Pathology Pomeranian Medical University Szczecin, Szczecin, Poland., Blomqvist C; Department of Oncology, Helsinki University Hospital University of Helsinki, Helsinki, Finland.; Department of Oncology Örebro University Hospital, Örebro, Sweden., Bojesen SE; Copenhagen General Population Study, Herlev and Gentofte Hospital Copenhagen University Hospital, Herlev, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital Copenhagen University Hospital, Herlev, Denmark.; Faculty of Health and Medical Sciences University of Copenhagen, Copenhagen, Denmark., Bonanni B; Division of Cancer Prevention and Genetics IEO, European Institute of Oncology IRCCS, Milan, Italy., Borg A; Department of Oncology Lund University and Skåne University Hospital, Lund, Sweden., Brauch H; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.; iFIT-Cluster of Excellence University of Tübingen, Tübingen, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany., Brenner H; Division of Clinical Epidemiology and Aging Research German Cancer Research Center (DKFZ), Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Burwinkel B; Molecular Epidemiology Group, C080 German Cancer Research Center (DKFZ), Heidelberg, Germany.; Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg University of Heidelberg, Heidelberg, Germany., Buys SS; Department of Medicine Huntsman Cancer Institute, Salt Lake City, UT, USA., Caldés T; Molecular Oncology Laboratory CIBERONC, Hospital Clinico San Carlos, IdISSC (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos), Madrid, Spain., Caligo MA; SOD Genetica Molecolare University Hospital, Pisa, Italy., Campa D; Department of Biology University of Pisa, Pisa, Italy.; Division of Cancer Epidemiology German Cancer Research Center (DKFZ), Heidelberg, Germany., Carter BD; Behavioral and Epidemiology Research Group American Cancer Society Atlanta, Atlanta, GA, USA., Castelao JE; Oncology and Genetics Unit Instituto de Investigacion Sanitaria Galicia Sur (IISGS), Xerencia de Xestion Integrada de Vigo-SERGAS, Vigo, Spain., Chang-Claude J; Division of Cancer Epidemiology German Cancer Research Center (DKFZ), Heidelberg, Germany.; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH) University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Chanock SJ; Division of Cancer Epidemiology and Genetics National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA., Chung WK; Departments of Pediatrics and Medicine, Columbia University, New York, NY, USA., Claes KBM; Centre for Medical Genetics Ghent University, Gent, Belgium., Clarke CL; Westmead Institute for Medical Research University of Sydney, Sydney, NSW, Australia., Collée JM; Department of Clinical Genetics Erasmus University Medical Center, Rotterdam, The Netherlands., Conroy DM; Centre for Cancer Genetic Epidemiology, Department of Oncology University of Cambridge, Cambridge, UK., Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Daly MB; Department of Clinical Genetics Fox Chase Cancer Center Philadelphia, Philadelphia, PA, USA., Devilee P; Department of Pathology Leiden University Medical Center, Leiden, The Netherlands.; Department of Human Genetics Leiden University Medical Center, Leiden, The Netherlands., Diez O; Oncogenetics Group Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.; Clinical and Molecular Genetics Area University Hospital Vall d'Hebron, Barcelona, Spain., Ding YC; Department of Population Sciences Beckman Research Institute of City of Hope, Duarte, CA, USA., Domchek SM; Basser Center for BRCA, Abramson Cancer Center University of Pennsylvania, Philadelphia, PA, USA., Dörk T; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Dos-Santos-Silva I; Department of Non-Communicable Disease Epidemiology London School of Hygiene and Tropical Medicine, London, UK., Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology University of Cambridge, Cambridge, UK., Dwek M; School of Life Sciences University of Westminster, London, UK., Eccles DM; Faculty of Medicine University of Southampton, Southampton, UK., Eliassen AH; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Epidemiology Harvard TH Chan School of Public Health, Boston, MA, USA., Engel C; Institute for Medical Informatics, Statistics and Epidemiology University of Leipzig, Leipzig, Germany., Eriksson M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Evans DG; Genomic Medicine, Division of Evolution and Genomic Sciences The University of Manchester, Manchester Academic Health Science Centre, Manchester Universities Foundation Trust, St Mary's Hospital, Manchester, UK.; Genomic Medicine, North West Genomics hub Manchester Academic Health Science Centre, Manchester Universities Foundation Trust, St Mary's Hospital, Manchester, UK., Fasching PA; David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology University of California at Los Angeles, Los Angeles, CA, USA.; Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN University Hospital Erlangen, Friedrich-Alexander-University, Erlangen-Nuremberg, Erlangen, Germany., Flyger H; Department of Breast Surgery, Herlev and Gentofte Hospital Copenhagen University Hospital, Herlev, Denmark., Fostira F; Molecular Diagnostics Laboratory, INRASTES National Centre for Scientific Research íDemokritosí, Athens, Greece., Friedman E; The Susanne Levy Gertner Oncogenetics Unit Chaim Sheba Medical Center, Ramat Gan, Israel.; Sackler Faculty of Medicine Tel Aviv University, Ramat Aviv, Israel., Fritschi L; School of Public Health Curtin University, Perth, Western Australia, Australia., Frost D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Gago-Dominguez M; Genomic Medicine Group, Galician Foundation of Genomic Medicine Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain.; Moores Cancer Center University of California, San Diego La Jolla, CA, USA., Gapstur SM; Behavioral and Epidemiology Research Group American Cancer Society Atlanta, Atlanta, GA, USA., Garber J; Division of Cancer Genetics and Prevention, Dana-Farber Cancer Institute, Boston, MA, USA., Garcia-Barberan V; Medical Oncology Department, Hospital Clínico San Carlos Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain., García-Closas M; Division of Cancer Epidemiology and Genetics National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA., García-Sáenz JA; Medical Oncology Department, Hospital Clínico San Carlos Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain., Gaudet MM; Behavioral and Epidemiology Research Group American Cancer Society Atlanta, Atlanta, GA, USA., Gayther SA; Center for Bioinformatics and Functional Genomics and the Cedars Sinai Genomics Core Cedars-Sinai Medical Center, Los Angeles, CA, USA., Gehrig A; Department of Human Genetics University Würzburg, Würzburg, Germany., Georgoulias V; Department of Medical Oncology University Hospital of Heraklion, Heraklion, Greece., Giles GG; Cancer Epidemiology Division Cancer Council Victoria, Melbourne, VIC, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health Monash University, Clayton, VIC, Australia., Godwin AK; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS, USA., Goldberg MS; Department of Medicine, McGill University, Montréal, QC, Canada.; Division of Clinical Epidemiology, Royal Victoria Hospital McGill University Montréal, Montréal, QC, Canada., Goldgar DE; Huntsman Cancer Institute and Department of Dermatology, University of Utah School of Medicine, Salt Lake City, UT, USA., González-Neira A; Human Cancer Genetics Programme Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Greene MH; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics National Cancer Institute, Bethesda, MD, USA., Guénel P; Cancer & Environment Group, Center for Research in Epidemiology and Population Health (CESP) INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France., Haeberle L; Department of Gynaecology and Obstetrics, University Hospital Erlangen Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany., Hahnen E; Center for Hereditary Breast and Ovarian Cancer Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO) Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Haiman CA; Department of Preventive Medicine, Keck School of Medicine University of Southern California, Los Angeles, CA, USA., Håkansson N; Department of Oncology, Södersjukhuset, Stockholm, Sweden., Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Department of Oncology, Södersjukhuset, Stockholm, Sweden., Hamann U; Molecular Genetics of Breast Cancer German Cancer Research Center (DKFZ), Heidelberg, Germany., Harrington PA; Centre for Cancer Genetic Epidemiology, Department of Oncology University of Cambridge, Cambridge, UK., Hart SN; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., He W; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Hogervorst FBL; Family Cancer Clinic, The Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands., Hollestelle A; Department of Medical Oncology, Family Cancer Clinic Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia., Horcasitas DJ; New Mexico Oncology Hematology Consultants, University of New Mexico, Albuquerque, NM, USA., Hulick PJ; Center for Medical Genetics NorthShore University HealthSystem, Evanston, IL, USA.; The University of Chicago Pritzker School of Medicine Chicago, Chicago, IL, USA., Hunter DJ; Department of Epidemiology Harvard TH Chan School of Public Health, Boston, MA, USA.; Program in Genetic Epidemiology and Statistical Genetics Harvard TH Chan School of Public Health Boston, Boston, MA, USA.; Nuffield Department of Population Health University of Oxford, Oxford, UK., Imyanitov EN; NN Petrov Institute of Oncology, St. Petersburg, Russia., Jager A; Department of Medical Oncology, Family Cancer Clinic Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Jakubowska A; Department of Genetics and Pathology Pomeranian Medical University Szczecin, Szczecin, Poland.; Independent Laboratory of Molecular Biology and Genetic Diagnostics Pomeranian Medical University, Szczecin, Poland., James PA; Sir Peter MacCallum Department of Oncology The University of Melbourne, Melbourne, VIC, Australia.; Parkville Familial Cancer Centre Peter MacCallum Cancer Center, Melbourne, VIC, Australia., Jensen UB; Department of Clinical Genetics Aarhus, University Hospital, Aarhus, Denmark., John EM; Department of Medicine, Division of Oncology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, USA., Jones ME; Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, USA., Kaaks R; Division of Cancer Epidemiology German Cancer Research Center (DKFZ), Heidelberg, Germany., Kapoor PM; Division of Cancer Epidemiology German Cancer Research Center (DKFZ), Heidelberg, Germany.; Division of Genetics and Epidemiology The Institute of Cancer Research, London, UK., Karlan BY; Faculty of Medicine University of Heidelberg, Heidelberg, Germany.; David Geffen School of Medicine, Department of Obstetrics and Gynecology University of California at Los Angeles, Los Angeles, CA, USA., Keeman R; Womenís Cancer Program at the Samuel Oschin Comprehensive Cancer Institute Cedars-Sinai Medical Center, Los Angeles, CA, USA., Khusnutdinova E; Institute of Biochemistry and Genetics Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia.; Division of Molecular Pathology The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands., Kiiski JI; Department of Genetics and Fundamental Medicine Bashkir State Medical University, Ufa, Russia., Ko YD; Department of Obstetrics and Gynecology, Helsinki University Hospital University of Helsinki, Helsinki, Finland., Kosma VM; Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH Johanniter Krankenhaus, Bonn, Germany.; Translational Cancer Research Area University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine University of Eastern Finland, Kuopio, Finland., Kraft P; Department of Epidemiology Harvard TH Chan School of Public Health, Boston, MA, USA.; Program in Genetic Epidemiology and Statistical Genetics Harvard TH Chan School of Public Health Boston, Boston, MA, USA., Kurian AW; Department of Medicine, Division of Oncology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, USA., Laitman Y; The Susanne Levy Gertner Oncogenetics Unit Chaim Sheba Medical Center, Ramat Gan, Israel., Lambrechts D; VIB Center for Cancer Biology, Leuven, Belgium.; Laboratory for Translational Genetics, Department of Human Genetics University of Leuven, Leuven, Belgium., Le Marchand L; Epidemiology Program University of Hawaii Cancer Center, Honolulu, HI, USA., Lester J; Faculty of Medicine University of Heidelberg, Heidelberg, Germany.; David Geffen School of Medicine, Department of Obstetrics and Gynecology University of California at Los Angeles, Los Angeles, CA, USA., Lesueur F; Genetic Epidemiology of Cancer team, Inserm, U900, Paris, France.; Institut Curie Paris, Paris, France.; Mines ParisTech Fontainebleau, Paris, France.; PSL University Paris, Paris, France., Lindstrom T; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Lopez-Fernández A; High Risk and Cancer Prevention Group Vall d'Hebron Institute of Oncology, Barcelona, Spain., Loud JT; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics National Cancer Institute, Bethesda, MD, USA., Luccarini C; Centre for Cancer Genetic Epidemiology, Department of Oncology University of Cambridge, Cambridge, UK., Mannermaa A; Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH Johanniter Krankenhaus, Bonn, Germany.; Translational Cancer Research Area University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine University of Eastern Finland, Kuopio, Finland., Manoukian S; Unit of Medical Genetics, Department of Medical Oncology and Hematology Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy., Margolin S; Department of Oncology, Södersjukhuset, Stockholm, Sweden.; Department of Clinical Science and Education, Södersjukhuset Karolinska Institutet, Stockholm, Sweden., Martens JWM; Department of Medical Oncology, Family Cancer Clinic Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Mebirouk N; Genetic Epidemiology of Cancer team, Inserm, U900, Paris, France.; Institut Curie Paris, Paris, France.; Mines ParisTech Fontainebleau, Paris, France.; PSL University Paris, Paris, France., Meindl A; Department of Gynecology and Obstetrics University of Munich, Campus Grosshadern, Munich, Germany., Miller A; NRG Oncology, Statistics and Data Management Center Roswell Park Cancer Institute, Buffalo, NY, USA., Milne RL; Cancer Epidemiology Division Cancer Council Victoria, Melbourne, VIC, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health Monash University, Clayton, VIC, Australia., Montagna M; Immunology and Molecular Oncology, Unit Veneto Institute of Oncology IOV - IRCCS, Padua, Italy., Nathanson KL; Basser Center for BRCA, Abramson Cancer Center University of Pennsylvania, Philadelphia, PA, USA., Neuhausen SL; Department of Population Sciences Beckman Research Institute of City of Hope, Duarte, CA, USA., Nevanlinna H; Department of Genetics and Fundamental Medicine Bashkir State Medical University, Ufa, Russia., Nielsen FC; Center for Genomic Medicine Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., O'Brien KM; Epidemiology Branch National Institute of Environmental Health Sciences, NIH Research Triangle Park, Durham, NC, USA., Olopade OI; Center for Clinical Cancer Genetics The University of Chicago, Chicago, IL, USA., Olson JE; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Olsson H; Department of Cancer Epidemiology, Clinical Sciences Lund University, Lund, 22242, Sweden., Osorio A; Human Cancer Genetics Programme Spanish National Cancer Research Centre (CNIO), Madrid, Spain.; Centro de Investigación en Red de Enfermedades Raras (CIBERER), Madrid, Spain., Ottini L; Department of Molecular Medicine University La Sapienza, Rome, Italy., Park-Simon TW; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Parsons MT; Department of Genetics and Computational Biology QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Pedersen IS; Molecular Diagnostics Aalborg University Hospital, Aalborg, Denmark.; Clinical Cancer Research Center Aalborg University Hospital, Aalborg, Denmark.; Department of Clinical Medicine Aalborg University, Aalborg, Denmark., Peshkin B; Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., Peterlongo P; Genome Diagnostics Program IFOM - the FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan, Italy., Peto J; Department of Non-Communicable Disease Epidemiology London School of Hygiene and Tropical Medicine, London, UK., Pharoah PDP; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology University of Cambridge, Cambridge, UK., Phillips KA; Department of Genetics and Computational Biology QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia.; Sir Peter MacCallum Department of Oncology The University of Melbourne, Melbourne, VIC, Australia., Polley EC; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Poppe B; Centre for Medical Genetics Ghent University, Gent, Belgium., Presneau N; School of Life Sciences University of Westminster, London, UK., Pujana MA; Translational Research Laboratory IDIBELL (Bellvitge Biomedical Research Institute), Catalan Institute of Oncology, CIBERONC, Barcelona, Spain., Punie K; Leuven Multidisciplinary Breast Center, Department of Oncology Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium., Radice P; Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan, Italy., Rantala J; Clinical Genetics Karolinska Institutet, Stockholm, Sweden., Rashid MU; Molecular Genetics of Breast Cancer German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Basic Sciences Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH & RC), Lahore, Pakistan., Rennert G; Clalit National Cancer Control Center Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel., Rennert HS; Clalit National Cancer Control Center Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel., Robson M; Clinical Genetics Service, Department of Medicine Memorial Sloan-Kettering Cancer Center, New York, NY, USA., Romero A; Medical Oncology Department Hospital Universitario Puerta de Hierro, Madrid, Spain., Rossing M; Center for Genomic Medicine Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Saloustros E; Department of Oncology University Hospital of Larissa, Larissa, Greece., Sandler DP; Epidemiology Branch National Institute of Environmental Health Sciences, NIH Research Triangle Park, Durham, NC, USA., Santella R; Department of Epidemiology, Mailman School of Public Health Columbia University, New York, NY, USA., Scheuner MT; Cancer Genetics and Prevention Program University of California San Francisco, San Francisco, CA, USA., Schmidt MK; Womenís Cancer Program at the Samuel Oschin Comprehensive Cancer Institute Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Division of Psychosocial Research and Epidemiology The Netherlands Cancer Institute - Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands., Schmidt G; Institute of Human Genetics Hannover Medical School, Hannover, Germany., Scott C; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Sharma P; Department of Internal Medicine, Division of Medical Oncology University of Kansas Medical Center, Westwood, KS, USA., Soucy P; Genomics Center, Centre Hospitalier Universitaire de Québec - Université Laval Research Center, Québec City, QC, Canada., Southey MC; Precision Medicine, School of Clinical Sciences at Monash Health Monash University, Clayton, VIC, Australia.; Department of Clinical Pathology The University of Melbourne, Melbourne, VIC, Australia., Spinelli JJ; Population Oncology BC Cancer, Vancouver, BC, Canada.; School of Population and Public Health University of British Columbia, Vancouver, BC, Canada., Steinsnyder Z; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics Memorial Sloan-Kettering Cancer Center, New York, NY, USA., Stone J; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia.; The Curtin UWA Centre for Genetic Origins of Health and Disease Curtin University and University of Western Australia, Perth, Western Australia, Australia., Stoppa-Lyonnet D; Service de Génétique Institut Curie, Paris, France.; Department of Tumour Biology INSERM U830, Paris, France.; Université Paris Descartes, Paris, France., Swerdlow A; Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, USA.; Division of Breast Cancer Research Institute of Cancer Research, London, UK., Tamimi RM; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Epidemiology Harvard TH Chan School of Public Health, Boston, MA, USA.; Program in Genetic Epidemiology and Statistical Genetics Harvard TH Chan School of Public Health Boston, Boston, MA, USA., Tapper WJ; Faculty of Medicine University of Southampton, Southampton, UK., Taylor JA; Epidemiology Branch National Institute of Environmental Health Sciences, NIH Research Triangle Park, Durham, NC, USA.; Epigenetic and Stem Cell Biology Laboratory National Institute of Environmental Health Sciences, NIH Research Triangle Park, Triangle Park, NC, USA., Terry MB; Department of Epidemiology, Mailman School of Public Health Columbia University, New York, NY, USA., Teulé A; Hereditary Cancer Program ONCOBELL-IDIBELL-IDIBGI-IGTP, Catalan Institute of Oncology, CIBERONC, Barcelona, Spain., Thull DL; Department of Medicine Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Tischkowitz M; Program in Cancer Genetics, Departments of Human Genetics and Oncology McGill University, Montréal, QC, Canada.; Department of Medical Genetics, National Institute for Health Research Cambridge Biomedical Research Center, University of Cambridge, Cambridge, UK., Toland AE; Department of Cancer Biology and Genetics The Ohio State University, Columbus, OH, USA., Torres D; Molecular Genetics of Breast Cancer German Cancer Research Center (DKFZ), Heidelberg, Germany.; Institute of Human Genetics Pontificia Universidad Javeriana, Bogota, Colombia., Trainer AH; Parkville Familial Cancer Centre Peter MacCallum Cancer Center, Melbourne, VIC, Australia.; Department of medicine University Of Melbourne, Melbourne, VIC, Australia., Truong T; Cancer & Environment Group, Center for Research in Epidemiology and Population Health (CESP) INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France., Tung N; Department of Medical Oncology Beth Israel Deaconess Medical Center, Boston, MA, USA., Vachon CM; Department of Health Science Research, Division of Epidemiology Mayo Clinic, Rochester, MN, USA., Vega A; Fundación Pública Galega Medicina Xenómica-SERGAS, Instituto de Investigación Sanitaria Santiago de Compostela (IDIS); CIBERER, Santiago de Compostela, Spain., Vijai J; Clinical Genetics Service, Department of Medicine Memorial Sloan-Kettering Cancer Center, New York, NY, USA.; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics Memorial Sloan-Kettering Cancer Center, New York, NY, USA., Wang Q; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Wappenschmidt B; Center for Hereditary Breast and Ovarian Cancer Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO) Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Weinberg CR; Biostatistics and Computational Biology Branch National Institute of Environmental Health Sciences, NIH Research Triangle Park, Triangle Park, NC, USA., Weitzel JN; Clinical Cancer Genomics City of Hope, Duarte, CA, USA., Wendt C; Department of Clinical Science and Education, Södersjukhuset Karolinska Institutet, Stockholm, Sweden., Wolk A; Institute of Environmental Medicine Karolinska Institutet, Stockholm, Sweden.; Department of Surgical Sciences Uppsala University, Uppsala, Sweden., Yadav S; Department of Oncology Mayo Clinic, Rochester, MN, USA., Yang XR; Division of Cancer Epidemiology and Genetics National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA., Yannoukakos D; Molecular Diagnostics Laboratory, INRASTES National Centre for Scientific Research íDemokritosí, Athens, Greece., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center Vanderbilt University School of Medicine, Nashville, TN, USA., Ziogas A; Department of Epidemiology, Genetic Epidemiology Research Institute University of California Irvine, Irvine, CA, USA., Zorn KK; Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Park SK; Department of Preventive Medicine Seoul National University College of Medicine, Seoul, Korea.; Department of Biomedical Sciences Seoul National University Graduate School, Seoul, Korea.; Cancer Research Institute Seoul National University, Seoul, Korea., Thomassen M; Department of Clinical Genetics Odense University Hospital, Odence C, Denmark., Offit K; Clinical Genetics Service, Department of Medicine Memorial Sloan-Kettering Cancer Center, New York, NY, USA.; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics Memorial Sloan-Kettering Cancer Center, New York, NY, USA., Schmutzler RK; Center for Hereditary Breast and Ovarian Cancer Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO) Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Couch FJ; Department of Laboratory Medicine and Pathology Mayo Clinic, Rochester, MN, USA., Simard J; Department of Epidemiology, Genetic Epidemiology Research Institute University of California Irvine, Irvine, CA, USA., Chenevix-Trench G; Department of Genetics and Computational Biology QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology University of Cambridge, Cambridge, UK., Andrieu N; Genetic Epidemiology of Cancer team, Inserm, U900, Paris, France. nadine.andrieu@curie.fr.; Institut Curie Paris, Paris, France. nadine.andrieu@curie.fr.; Mines ParisTech Fontainebleau, Paris, France. nadine.andrieu@curie.fr.; PSL University Paris, Paris, France. nadine.andrieu@curie.fr., Antoniou AC; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. aca20@medschl.cam.ac.uk.

مؤلفون مشاركون: GEMO Study Collaborators, EMBRACE Collaborators, KConFab Investigators, HEBON Investigators, ABCTB Investigators

المصدر: Nature communications [Nat Commun] 2021 Feb 17; Vol. 12 (1), pp. 1078. Date of Electronic Publication: 2021 Feb 17.

نوع المنشور: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Polymorphism, Single Nucleotide*, BRCA1 Protein/*genetics , BRCA2 Protein/*genetics , Breast Neoplasms/*genetics , Genetic Predisposition to Disease/*genetics , Genome-Wide Association Study/*methods, Adult ; Alleles ; Female ; Genotype ; Humans ; Linkage Disequilibrium ; Middle Aged ; Mutation ; Quantitative Trait Loci/genetics ; Risk Factors

المؤلفون: Escala-Garcia M; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands., Abraham J; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.; Cambridge Experimental Cancer Medicine Centre, Cambridge, UK.; Cambridge Breast Unit and NIHR Cambridge Biomedical Research Centre, University of Cambridge NHS Foundation Hospitals, Cambridge, UK., Andrulis IL; Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Canada., Anton-Culver H; Department of Epidemiology, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, CA, USA., Arndt V; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany., Ashworth A; UCSF Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA., Auer PL; Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI, USA., Auvinen P; Cancer Center, Kuopio University Hospital, Kuopio, Finland.; Institute of Clinical Medicine, Oncology, University of Eastern Finland, Kuopio, Finland.; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland., Beckmann MW; Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany., Beesley J; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Behrens S; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Benitez J; Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.; Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain., Bermisheva M; Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa, Russia., Blomqvist C; Department of Oncology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.; Department of Oncology, Örebro University Hospital, Örebro, Sweden., Blot W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA.; International Epidemiology Institute, Rockville, MD, USA., Bogdanova NV; Department of Radiation Oncology, Hannover Medical School, Hannover, Germany.; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany.; N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus., Bojesen SE; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bolla MK; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Børresen-Dale AL; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital-Radiumhospitalet, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway., Brauch H; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.; iFIT-Cluster of Excellence, University of Tuebingen, Tuebingen, Germany.; German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany., Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany., Brucker SY; Department of Gynecology and Obstetrics, University of Tübingen, Tübingen, Germany., Burwinkel B; Molecular Epidemiology Group, C080, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg, University of Heidelberg, Heidelberg, Germany., Caldas C; Cancer Research UK Cambridge Institute, Department of Oncology, Li Ka Shing Centre, University of Cambridge, Cambridge, UK.; Breast Cancer Programme, CRUK Cambridge Cancer Centre and NIHR Biomedical Research Centre, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Canzian F; Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany., Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Chanock SJ; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Chin SF; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Clarke CL; Westmead Institute for Medical Research, University of Sydney, Sydney, NSW, Australia., Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Cox A; Department of Oncology and Metabolism, Sheffield Institute for Nucleic Acids (SInFoNiA), University of Sheffield, Sheffield, UK., Cross SS; Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield, UK., Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, PA, USA., Dennis J; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Devilee P; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands., Dunn JA; Warwick Clinical Trials Unit, University of Warwick, Coventry, UK., Dunning AM; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Dwek M; Department of Biomedical Sciences, Faculty of Science and Technology, University of Westminster, London, UK., Earl HM; Cambridge Breast Unit and NIHR Cambridge Biomedical Research Centre, University of Cambridge NHS Foundation Hospitals, Cambridge, UK.; Department of Oncology, University of Cambridge, Cambridge, UK., Eccles DM; Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK., Eliassen AH; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Ellberg C; Department of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden., Evans DG; Division of Evolution and Genomic Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.; Genomic Medicine, St Mary's Hospital, Manchester Centre for Genomic Medicine, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.; NIHR Manchester Biomedical Research Centre, Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust, Manchester, UK., Fasching PA; Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.; Division of Hematology and Oncology, Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA., Figueroa J; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.; Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh Medical School, Edinburgh, UK.; Cancer Research UK Edinburgh Centre, Edinburgh, UK., Flyger H; Department of Breast Surgery, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Gago-Dominguez M; Genomic Medicine Group, Galician Foundation of Genomic Medicine, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain.; Moores Cancer Center, University of California San Diego, La Jolla, CA, USA., Gapstur SM; Epidemiology Research Program, American Cancer Society, Atlanta, GA, USA., García-Closas M; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK., García-Sáenz JA; Medical Oncology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain., Gaudet MM; Epidemiology Research Program, American Cancer Society, Atlanta, GA, USA., George A; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Giles GG; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia.; Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, VIC, Australia., Goldgar DE; Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA., González-Neira A; Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Grip M; Department of Surgery, Oulu University Hospital, University of Oulu, Oulu, Finland., Guénel P; Cancer & Environment Group, Center for Research in Epidemiology and Population Health (CESP), University Paris-Saclay, INSERM, University Paris-Sud, Villejuif, France., Guo Q; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Håkansson N; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Harrington PA; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Hiller L; Warwick Clinical Trials Unit, University of Warwick, Coventry, UK., Hooning MJ; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia., Howell A; Division of Cancer Sciences, University of Manchester, Manchester, UK., Huang CS; Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan., Huang G; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Hunter DJ; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Jakubowska A; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.; Independent Laboratory of Molecular Biology and Genetic Diagnostics, Pomeranian Medical University, Szczecin, Poland., John EM; Division of Oncology, Department of Medicine, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA., Kaaks R; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Kapoor PM; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Faculty of Medicine, University of Heidelberg, Heidelberg, Germany., Keeman R; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands., Kitahara CM; Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Koppert LB; Department of Surgical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Kraft P; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Kristensen VN; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital-Radiumhospitalet, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway., Lambrechts D; VIB, VIB Center for Cancer Biology, Leuven, Belgium.; Laboratory for Translational Genetics, Department of Human Genetics, University of Leuven, Leuven, Belgium., Le Marchand L; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, USA., Lejbkowicz F; Carmel Medical Center and Technion Faculty of Medicine, Clalit National Cancer Control Center, Haifa, Israel., Lindblom A; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.; Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden., Lubiński J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Mannermaa A; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland.; Department of Clinical Pathology, Imaging Center, Kuopio University Hospital, Kuopio, Finland., Manoochehri M; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Manoukian S; Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano (INT), Milan, Italy., Margolin S; Department of Oncology, Sšdersjukhuset, Stockholm, Sweden.; Department of Clinical Science and Education, Sšdersjukhuset, Karolinska Institutet, Stockholm, Sweden., Martinez ME; Moores Cancer Center, University of California San Diego, La Jolla, CA, USA.; Department of Family Medicine and Public Health, University of California San Diego, La Jolla, CA, USA., Maurer T; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Mavroudis D; Department of Medical Oncology, University Hospital of Heraklion, Heraklion, Greece., Meindl A; Department of Gynecology and Obstetrics, Ludwig Maximilian University of Munich, Munich, Germany., Milne RL; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia., Mulligan AM; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Laboratory Medicine Program, University Health Network, Toronto, ON, Canada., Neuhausen SL; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA., Nevanlinna H; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Newman WG; Division of Evolution and Genomic Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.; Genomic Medicine, St Mary's Hospital, Manchester Centre for Genomic Medicine, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Olshan AF; Department of Epidemiology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Olson JE; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Olsson H; Department of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden., Orr N; Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, Ireland, UK., Peterlongo P; Genome Diagnostics Program, IFOM - the FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan, Italy., Petridis C; Research Oncology, Guy's Hospital, King's College London, London, UK., Prentice RL; Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Presneau N; Department of Biomedical Sciences, Faculty of Science and Technology, University of Westminster, London, UK., Punie K; Department of Oncology, Leuven Multidisciplinary Breast Center, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium., Ramachandran D; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Rennert G; Carmel Medical Center and Technion Faculty of Medicine, Clalit National Cancer Control Center, Haifa, Israel., Romero A; Medical Oncology Department, Hospital Universitario Puerta de Hierro, Madrid, Spain., Sachchithananthan M; Westmead Institute for Medical Research, University of Sydney, Sydney, NSW, Australia., Saloustros E; Department of Oncology, University Hospital of Larissa, Larissa, Greece., Sawyer EJ; Research Oncology, Guy's Hospital, King's College London, London, UK., Schmutzler RK; Center for Hereditary Breast and Ovarian Cancer, University Hospital of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany., Schwentner L; Department of Gynaecology and Obstetrics, University Hospital Ulm, Ulm, Germany., Scott C; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Simard J; Genomics Center, Research Center, Centre Hospitalier Universitaire de Québec - Université Laval, Québec City, QC, Canada., Sohn C; National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany., Southey MC; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia.; Department of Clinical Pathology, The University of Melbourne, Melbourne, VIC, Australia., Swerdlow AJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.; Division of Breast Cancer Research, The Institute of Cancer Research, London, UK., Tamimi RM; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Tapper WJ; Faculty of Medicine, University of Southampton, Southampton, UK., Teixeira MR; Department of Genetics, Portuguese Oncology Institute, Porto, Portugal.; Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal., Terry MB; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA., Thorne H; Peter MacCallum Cancer Center, Melbourne, VIC, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia., Tollenaar RAEM; Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands., Tomlinson I; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.; Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK., Troester MA; Department of Epidemiology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Truong T; Cancer & Environment Group, Center for Research in Epidemiology and Population Health (CESP), University Paris-Saclay, INSERM, University Paris-Sud, Villejuif, France., Turnbull C; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Vachon CM; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., van der Kolk LE; Family Cancer Clinic, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands., Wang Q; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Winqvist R; Biocenter Oulu, Cancer and Translational Medicine Research Unit, Laboratory of Cancer Genetics and Tumor Biology, University of Oulu, Oulu, Finland.; Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre Oulu, Oulu, Finland., Wolk A; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Surgical Sciences, Uppsala University, Uppsala, Sweden., Yang XR; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Ziogas A; Department of Epidemiology, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, CA, USA., Pharoah PDP; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Department of Oncology, Sšdersjukhuset, Stockholm, Sweden., Wessels LFA; Division of Molecular Carcinogenesis, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.; Faculty of EEMCS, Delft University of Technology, Delft, The Netherlands., Chenevix-Trench G; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Bader GD; Department of Molecular Genetics, University of Toronto, Toronto, Canada.; The Donnelly Centre, University of Toronto, Toronto, ON, Canada., Dörk T; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Easton DF; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Canisius S; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands. s.canisius@nki.nl.; Division of Molecular Carcinogenesis, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands. s.canisius@nki.nl., Schmidt MK; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands. mk.schmidt@nki.nl.; Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands. mk.schmidt@nki.nl.

المصدر: Nature communications [Nat Commun] 2020 Jan 16; Vol. 11 (1), pp. 312. Date of Electronic Publication: 2020 Jan 16.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Variation* , Genome-Wide Association Study* , Germ Cells*, Breast Neoplasms/*genetics, Apoptosis ; Circadian Clocks ; Computational Biology ; Female ; GTP-Binding Protein alpha Subunits/genetics ; GTP-Binding Protein alpha Subunits, Gq-G11/genetics ; Gene Regulatory Networks ; Genotype ; Humans ; Prognosis ; Receptors, Estrogen/genetics ; Signal Transduction

المؤلفون: Ferreira MA; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, 4006, Australia. Manuel.Ferreira@qimr.edu.au., Gamazon ER; Division of Genetic Medicine, Department of Medicine, Vanderbilt University, Nashville, TN, 37235, USA.; Clare Hall, University of Cambridge, Cambridge, CB3 9AL, UK., Al-Ejeh F; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, 4006, Australia., Aittomäki K; Department of Clinical Genetics, Helsinki University Hospital, University of Helsinki, 00290, Helsinki, Finland., Andrulis IL; Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, ON, M5G 1X5, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada., Anton-Culver H; Department of Epidemiology, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, CA, USA, 92617., Arason A; Department of Pathology, Landspitali University Hospital, 101, Reykjavik, Iceland.; BMC (Biomedical Centre), Faculty of Medicine, University of Iceland, 101, Reykjavik, Iceland., Arndt V; Division of Clinical Epidemiology and Aging Research, C070, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany., Aronson KJ; Department of Public Health Sciences, and Cancer Research Institute, Queen's University, Kingston, ON, K7L 3N6, Canada., Arun BK; Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Asseryanis E; Dept of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, 1090, Vienna, Austria., Azzollini J; Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), 20133, Milan, Italy., Balmaña J; Oncogenetics Group, Vall dHebron Institute of Oncology (VHIO), 8035, Barcelona, Spain.; Department of Medical Oncology, Vall d'Hebron Institute of Oncology (VHIO), University Hospital, Vall d'Hebron, 08035, Barcelona, Spain., Barnes DR; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Barrowdale D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Beckmann MW; Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, 91054, Erlangen, Germany., Behrens S; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany., Benitez J; Centro de Investigación en Red de Enfermedades Raras (CIBERER), 46010, Valencia, Spain.; Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), 28029, Madrid, Spain., Bermisheva M; Institute of Biochemistry and Genetics, Ufa Federal Research Centre of Russian Academy of Sciences, 450054, Ufa, Russia., Białkowska K; Department of Genetics and Pathology, Pomeranian Medical University, 71-252, Szczecin, Poland., Blomqvist C; Department of Oncology, Helsinki University Hospital, University of Helsinki, Helsinki, 00290, Finland.; Department of Oncology, Örebro University Hospital, 70185, Örebro, Sweden., Bogdanova NV; Department of Radiation Oncology, Hannover Medical School, 30625, Hannover, Germany.; Gynaecology Research Unit, Hannover Medical School, 30625, Hannover, Germany.; N.N. Alexandrov Research Institute of Oncology and Medical Radiology, 223040, Minsk, Belarus., Bojesen SE; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, 2730, Herlev, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, 2730, Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark., Bolla MK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Borg A; Department of Oncology, Lund University and Skåne University Hospital, 222 41, Lund, Sweden., Brauch H; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, 70376, Stuttgart, Germany.; University of Tübingen, 72074, Tübingen, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany., Brenner H; Division of Clinical Epidemiology and Aging Research, C070, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), 69120, Heidelberg, Germany., Broeks A; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, 1066 CX, Amsterdam, The Netherlands., Burwinkel B; Molecular Epidemiology Group, C080, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg, University of Heidelberg, 69120, Heidelberg, Germany., Caldés T; Molecular Oncology Laboratory, CIBERONC, Hospital Clinico San Carlos, IdISSC (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos), 28040, Madrid, Spain., Caligo MA; Section of Molecular Genetics, Dept. of Laboratory Medicine, University Hospital of Pisa, 56126, Pisa, Italy., Campa D; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; Department of Biology, University of Pisa, 56126, Pisa, Italy., Campbell I; Research Department, Peter MacCallum Cancer Center, Melbourne, VIC, 3000, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, 3000, Australia., Canzian F; Genomic Epidemiology Group, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany., Carter J; Department of Gynaecological Oncology, Chris O'Brien Lifehouse and The University of Sydney, Camperdown, NSW, 2050, Australia., Carter BD; Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA, USA, 30303., Castelao JE; Oncology and Genetics Unit, Instituto de Investigacion Sanitaria Galicia Sur (IISGS), Xerencia de Xestion Integrada de Vigo-SERGAS, 36312, Vigo, Spain., Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany., Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, 20850, USA., Christiansen H; Department of Radiation Oncology, Hannover Medical School, 30625, Hannover, Germany., Chung WK; Departments of Pediatrics and Medicine, Columbia University, New York, NY, 10032, USA., Claes KBM; Centre for Medical Genetics, Ghent University, Gent, 9000, Belgium., Clarke CL; Westmead Institute for Medical Research, University of Sydney, Sydney, NSW, 2145, Australia., Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA., Cox A; Sheffield Institute for Nucleic Acids (SInFoNiA), Department of Oncology and Metabolism, University of Sheffield, Sheffield, S10 2TN, UK., Cross SS; Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield, S10 2TN, UK., Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 65, Stockholm, Sweden., Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA., de la Hoya M; Molecular Oncology Laboratory, CIBERONC, Hospital Clinico San Carlos, IdISSC (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos), 28040, Madrid, Spain., Dennis J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Devilee P; Department of Pathology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands.; Department of Human Genetics, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands., Diez O; Oncogenetics Group, Vall dHebron Institute of Oncology (VHIO), 8035, Barcelona, Spain.; Clinical and Molecular Genetics Area, University Hospital Vall dHebron, Barcelona, 08035, Spain., Dörk T; Gynaecology Research Unit, Hannover Medical School, 30625, Hannover, Germany., Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK., Dwek M; Department of Biomedical Sciences, Faculty of Science and Technology, University of Westminster, London, W1B 2HW, UK., Eccles DM; Faculty of Medicine, University of Southampton, Southampton, SO17 1BJ, UK., Ejlertsen B; Department of Oncology, Rigshospitalet, Copenhagen University Hospital, DK-2100, Copenhagen, Denmark., Ellberg C; Department of Cancer Epidemiology, Clinical Sciences, Lund University, 222 42, Lund, Sweden., Engel C; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, 04107, Leipzig, Germany., Eriksson M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 65, Stockholm, Sweden., Fasching PA; Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, 91054, Erlangen, Germany.; David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, Los Angeles, CA, 90095, USA., Fletcher O; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW7 3RP, UK., Flyger H; Department of Breast Surgery, Herlev and Gentofte Hospital, Copenhagen University Hospital, 2730, Herlev, Denmark., Friedman E; The Susanne Levy Gertner Oncogenetics Unit, Chaim Sheba Medical Center, 52621, Ramat Gan, Israel.; Sackler Faculty of Medicine, Tel Aviv University, 69978, Ramat Aviv, Israel., Frost D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Gabrielson M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 65, Stockholm, Sweden., Gago-Dominguez M; Genomic Medicine Group, Galician Foundation of Genomic Medicine, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, SERGAS, 15706, Santiago de Compostela, Spain.; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92037, USA., Ganz PA; Schools of Medicine and Public Health, Division of Cancer Prevention & Control Research, Jonsson Comprehensive Cancer Centre, UCLA, Los Angeles, CA, 90096-6900, USA., Gapstur SM; Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA, USA, 30303., Garber J; Cancer Risk and Prevention Clinic, Dana-Farber Cancer Institute, Boston, MA, 02215, USA., García-Closas M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, 20850, USA.; Division of Genetics and Epidemiology, Institute of Cancer Research, London, SM2 5NG, UK., García-Sáenz JA; Medical Oncology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC), 28040, Madrid, Spain., Gaudet MM; Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA, USA, 30303., Giles GG; Cancer Epidemiology & Intelligence Division, Cancer Council Victoria, Melbourne, VIC, 3004, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, 3010, Australia.; Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, VIC, 3004, Australia., Glendon G; Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, ON, M5G 1X5, Canada., Godwin AK; Department of Pathology and Laboratory Medicine, Kansas University Medical Center, Kansas City, KS, 66160, USA., Goldberg MS; Department of Medicine, McGill University, Montréal, QC, H4A 3J1, Canada.; Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University, Montréal, QC, H4A 3J1, Canada., Goldgar DE; Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, 84112, USA., González-Neira A; Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), 28029, Madrid, Spain., Greene MH; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20850-9772, USA., Gronwald J; Department of Genetics and Pathology, Pomeranian Medical University, 71-252, Szczecin, Poland., Guénel P; Cancer & Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, 94805, Villejuif, France., Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA., Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 65, Stockholm, Sweden.; Department of Oncology, Södersjukhuset, 118 83, Stockholm, Sweden., Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany., He W; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 65, Stockholm, Sweden., Heyworth J; School of Population and Global Health, The University of Western Australia, Perth, WA, 6009, Australia., Hogervorst FBL; Family Cancer Clinic, The Netherlands Cancer Institute - Antoni van Leeuwenhoek hospital, Amsterdam, 1066 CX, The Netherlands., Hollestelle A; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, 3015 CN, The Netherlands., Hoover RN; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, 20850, USA., Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, 3010, Australia., Hulick PJ; Center for Medical Genetics, NorthShore University HealthSystem, Evanston, IL, 60201, USA.; The University of Chicago Pritzker School of Medicine, Chicago, IL, 60637, USA., Humphreys K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 65, Stockholm, Sweden., Imyanitov EN; N.N. Petrov Institute of Oncology. St., Petersburg, 197758, Russia., Isaacs C; Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20007, USA., Jakimovska M; Research Centre for Genetic Engineering and Biotechnology 'Georgi D. Efremov', Macedonian Academy of Sciences and Arts, Skopje, 1000, Republic of Macedonia., Jakubowska A; Department of Genetics and Pathology, Pomeranian Medical University, 71-252, Szczecin, Poland.; Independent Laboratory of Molecular Biology and Genetic Diagnostics, Pomeranian Medical University, Szczecin, 71-252, Poland., James PA; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, 3000, Australia.; Parkville Familial Cancer Centre, Peter MacCallum Cancer Center, Melbourne, VIC, 3000, Australia., Janavicius R; Hematology, oncology and transfusion medicine center, Dept. of Molecular and Regenerative Medicine, Vilnius University Hospital Santariskiu Clinics, Vilnius, 08410, Lithuania., Jankowitz RC; Department of Medicine, Division of Hematology/Oncology, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15232, USA., John EM; Department of Medicine, Division of Oncology, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, 94304, USA., Johnson N; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW7 3RP, UK., Joseph V; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, USA., Karlan BY; David Geffen School of Medicine, Department of Obstetrics and Gynecology, University of California at Los Angeles, Los Angeles, CA, 90095, USA., Khusnutdinova E; Institute of Biochemistry and Genetics, Ufa Federal Research Centre of Russian Academy of Sciences, 450054, Ufa, Russia.; Department of Genetics and Fundamental Medicine, Bashkir State Medical University, 450076, Ufa, Russia., Kiiski JI; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, 00290, Finland., Ko YD; Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus, Bonn, 53177, Germany., Jones ME; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SM2 5NG, UK., Konstantopoulou I; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Athens, 15310, Greece., Kristensen VN; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital-Radiumhospitalet, Oslo, 0379, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, 0450, Norway., Laitman Y; The Susanne Levy Gertner Oncogenetics Unit, Chaim Sheba Medical Center, 52621, Ramat Gan, Israel., Lambrechts D; VIB Center for Cancer Biology, VIB, Leuven, 3001, Belgium.; Laboratory for Translational Genetics, Department of Human Genetics, University of Leuven, Leuven, 3000, Belgium., Lazaro C; Molecular Diagnostic Unit, Hereditary Cancer Program, ICO-IDIBELL (Bellvitge Biomedical Research Institute, Catalan Institute of Oncology), CIBERONC, Barcelona, 08908, Spain., Leslie G; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Lester J; David Geffen School of Medicine, Department of Obstetrics and Gynecology, University of California at Los Angeles, Los Angeles, CA, 90095, USA., Lesueur F; Genetic Epidemiology of Cancer team, Inserm U900, Paris, 75005, France.; Institut Curie, Paris, 75005, France.; Mines ParisTech, Fontainebleau, 77305, France., Lindström S; Department of Epidemiology, University of Washington School of Public Health, Seattle, WA, 98195, USA.; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Long J; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA., Loud JT; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20850-9772, USA., Lubiński J; Department of Genetics and Pathology, Pomeranian Medical University, 71-252, Szczecin, Poland., Makalic E; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, 3010, Australia., Mannermaa A; Translational Cancer Research Area, University of Eastern Finland, Kuopio, 70210, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, 70210, Finland.; Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, 70210, Finland., Manoochehri M; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany., Margolin S; Department of Oncology, Södersjukhuset, 118 83, Stockholm, Sweden.; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, 118 83, Sweden., Maurer T; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany., Mavroudis D; Department of Medical Oncology, University Hospital of Heraklion, Heraklion, 711 10, Greece., McGuffog L; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Meindl A; Department of Gynecology and Obstetrics, University of Munich, Campus Großhadern, Munich, 81377, Germany., Menon U; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials & Methodology, University College London, London, WC1V 6LJ, UK., Michailidou K; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; Department of Electron Microscopy/Molecular Pathology and The Cyprus School of Molecular Medicine, The Cyprus Institute of Neurology & Genetics, Nicosia, 1683, Cyprus., Miller A; NRG Oncology, Statistics and Data Management Center, Roswell Park Cancer Institute, Buffalo, NY, 14263, USA., Montagna M; Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS, Padua, 35128, Italy., Moreno F; Medical Oncology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC), 28040, Madrid, Spain., Moserle L; Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS, Padua, 35128, Italy., Mulligan AM; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, M5S 1A8, Canada.; Laboratory Medicine Program, University Health Network, Toronto, ON, M5G 2C4, Canada., Nathanson KL; Basser Center for BRCA, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, 19066, USA., Neuhausen SL; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, 91010, USA., Nevanlinna H; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, 00290, Finland., Nevelsteen I; Leuven Multidisciplinary Breast Center, Department of Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, 3000, Belgium., Nielsen FC; Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, DK-2100, Denmark., Nikitina-Zake L; Latvian Biomedical Research and Study Centre, Riga, LV-1067, Latvia., Nussbaum RL; Cancer Genetics and Prevention Program, University of California San Francisco, San Francisco, CA, 94143-1714, USA., Offit K; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, USA.; Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, USA., Olah E; Department of Molecular Genetics, National Institute of Oncology, Budapest, 1122, Hungary., Olopade OI; Center for Clinical Cancer Genetics, The University of Chicago, Chicago, IL, 60637, USA., Olsson H; Department of Cancer Epidemiology, Clinical Sciences, Lund University, 222 42, Lund, Sweden., Osorio A; Centro de Investigación en Red de Enfermedades Raras (CIBERER), 46010, Valencia, Spain.; Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), 28029, Madrid, Spain., Papp J; Department of Molecular Genetics, National Institute of Oncology, Budapest, 1122, Hungary., Park-Simon TW; Gynaecology Research Unit, Hannover Medical School, 30625, Hannover, Germany., Parsons MT; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, 4006, Australia., Pedersen IS; Molecular Diagnostics, Aalborg University Hospital, Aalborg, 9000, Denmark.; Clinical Cancer Research Center, Aalborg University Hospital, Aalborg, 9000, Denmark.; Department of Clinical Medicine, Aalborg University, Aalborg, 9000, Denmark., Peixoto A; Department of Genetics, Portuguese Oncology Institute, Porto, 4220-072, Portugal., Peterlongo P; Genome Diagnostics Program, IFOM - the FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan, 20139, Italy., Pharoah PDP; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK., Plaseska-Karanfilska D; Research Centre for Genetic Engineering and Biotechnology 'Georgi D. Efremov', Macedonian Academy of Sciences and Arts, Skopje, 1000, Republic of Macedonia., Poppe B; Centre for Medical Genetics, Ghent University, Gent, 9000, Belgium., Presneau N; Department of Biomedical Sciences, Faculty of Science and Technology, University of Westminster, London, W1B 2HW, UK., Radice P; Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan, 20133, Italy., Rantala J; Clinical Genetics, Karolinska Institutet, Stockholm, 171 76, Sweden., Rennert G; Clalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, Haifa, 35254, Israel., Risch HA; Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, 06510, USA., Saloustros E; Department of Oncology, University Hospital of Larissa, Larissa, 411 10, Greece., Sanden K; City of Hope Clinical Cancer Genetics Community Research Network, Duarte, CA, 91010, USA., Sawyer EJ; Research Oncology, Guy's Hospital, King's College London, London, SE1 9RT, UK., Schmidt MK; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, 1066 CX, Amsterdam, The Netherlands.; Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek hospital, Amsterdam, 1066 CX, The Netherlands., Schmutzler RK; Center for Hereditary Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, 50937, Germany.; Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937, Cologne, Germany., Sharma P; Department of Internal Medicine, Division of Oncology, University of Kansas Medical Center, Westwood, KS, 66205, USA., Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA., Simard J; Genomics Center, Centre Hospitalier Universitaire de Québec - Université Laval, Research Center, Québec City, QC, G1V 4G2, Canada., Singer CF; Dept of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, 1090, Vienna, Austria., Soucy P; Genomics Center, Centre Hospitalier Universitaire de Québec - Université Laval, Research Center, Québec City, QC, G1V 4G2, Canada., Southey MC; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, 3168, Australia.; Department of Clinical Pathology, The University of Melbourne, Melbourne, VIC, 3010, Australia., Spinelli JJ; Population Oncology, BC Cancer, Vancouver, BC, V5Z 1G1, Canada.; School of Population and Public Health, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada., Spurdle AB; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, 4006, Australia., Stone J; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, 3010, Australia.; The Curtin UWA Centre for Genetic Origins of Health and Disease, Curtin University and University of Western Australia, Perth, WA, 6000, Australia., Swerdlow AJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SM2 5NG, UK.; Division of Breast Cancer Research, The Institute of Cancer Research, London, SW7 3RP, UK., Tapper WJ; Faculty of Medicine, University of Southampton, Southampton, SO17 1BJ, UK., Taylor JA; Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, 27709, USA.; Epigenetic and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, 27709, USA., Teixeira MR; Department of Genetics, Portuguese Oncology Institute, Porto, 4220-072, Portugal.; Biomedical Sciences Institute (ICBAS), University of Porto, Porto, 4050-013, Portugal., Terry MB; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, 10032, USA., Teulé A; Genetic Counseling Unit, Hereditary Cancer Program, IDIBELL (Bellvitge Biomedical Research Institute),Catalan Institute of Oncology, CIBERONC, Barcelona, 08908, Spain., Thomassen M; Department of Clinical Genetics, Odense University Hospital, Odence C, 5000, Denmark., Thöne K; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany., Thull DL; Department of Medicine, Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA., Tischkowitz M; Program in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, Montréal, QC, H4A 3J1, Canada.; Department of Medical Genetics, University of Cambridge, Cambridge, CB2 0QQ, UK., Toland AE; Department of Cancer Biology and Genetics, The Ohio State University, Columbus, OH, 43210, USA., Torres D; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; Institute of Human Genetics, Pontificia Universidad Javeriana, Bogota, 110231, Colombia., Truong T; Cancer & Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, 94805, Villejuif, France., Tung N; Department of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA., Vachon CM; Department of Health Science Research, Division of Epidemiology, Mayo Clinic, Rochester, MN, 55905, USA., van Asperen CJ; Department of Clinical Genetics, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands., van den Ouweland AMW; Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, 3015 CN, The Netherlands., van Rensburg EJ; Department of Genetics, University of Pretoria, Arcadia, 0007, South Africa., Vega A; Fundación Pública galega Medicina Xenómica-SERGAS, Grupo de Medicina Xenómica-USC, CIBERER, IDIS, Santiago de Compostela, Spain., Viel A; Division of Functional onco-genomics and genetics, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano, 33081, Italy., Wang Q; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Wappenschmidt B; Center for Hereditary Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, 50937, Germany.; Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937, Cologne, Germany., Weitzel JN; Clinical Cancer Genomics, City of Hope, Duarte, CA, 91010, USA., Wendt C; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, 118 83, Sweden., Winqvist R; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, 90570, Finland.; Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre Oulu, Oulu, 90570, Finland., Yang XR; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, 20850, USA., Yannoukakos D; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Athens, 15310, Greece., Ziogas A; Department of Epidemiology, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, CA, USA, 92617., Kraft P; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, 02115, MA, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA., Antoniou AC; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA., Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK., Milne RL; Cancer Epidemiology & Intelligence Division, Cancer Council Victoria, Melbourne, VIC, 3004, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, 3010, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, 3168, Australia., Beesley J; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, 4006, Australia., Chenevix-Trench G; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, 4006, Australia.

مؤلفون مشاركون: EMBRACE Collaborators, GC-HBOC Study Collaborators, GEMO Study Collaborators, ABCTB Investigators, HEBON Investigators, BCFR Investigators

المصدر: Nature communications [Nat Commun] 2019 Apr 15; Vol. 10 (1), pp. 1741. Date of Electronic Publication: 2019 Apr 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Predisposition to Disease*, Breast Neoplasms/*genetics, Female ; Gene Expression Profiling ; Genome-Wide Association Study ; Humans ; Quantitative Trait Loci

المؤلفون: Lawrenson K; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA., Kar S; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK., McCue K; QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia., Kuchenbaeker K; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK., Michailidou K; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK., Tyrer J; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK., Beesley J; QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia., Ramus SJ; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA., Li Q; Medical College, Xiamen University, Xiamen 361102, China.; Department of Medical Oncology, The Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA., Delgado MK; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA., Lee JM; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA., Aittomäki K; Department of Clinical Genetics, Helsinki University Hospital, University of Helsinki, Helsinki 00029 HUS, Finland., Andrulis IL; Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada., Anton-Culver H; Department of Epidemiology, Genetic Epidemiology Research Institute, School of Medicine, University of California Irvine, Irvine, California 92697, USA., Arndt V; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany., Arun BK; University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Arver B; Department of Oncology, Karolinska University Hospital, Stockholm 171 77, Sweden., Bandera EV; Cancer Prevention and Control, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey 08903, USA., Barile M; Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia, Milan 20141, Italy., Barkardottir RB; Department of Pathology, Landspitali University Hospital and BMC (Biomedical Centre), Faculty of Medicine, University of Iceland, Reykjavik 600169-2039, Iceland., Barrowdale D; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK., Beckmann MW; University Hospital Erlangen, Department of Gynecology and Obstetrics, Friedrich-Alexander-University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen 91054, Germany., Benitez J; Human Cancer Genetics Program, Spanish National Cancer Research Centre, Madrid E-28029, Spain.; Centro de Investigación en Red de Enfermedades Raras, Valencia 28029, Spain., Berchuck A; Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina 27710, USA., Bisogna M; Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York 10065, USA., Bjorge L; Department of Gynecology and Obstetrics, Haukeland University Hospital, 5021 Bergen, Norway.; Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen, N-5020 Bergen, Norway., Blomqvist C; Department of Oncology, Helsinki University Hospital, University of Helsinki, Helsinki FIN-00029, Finland., Blot W; Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA.; International Epidemiology Institute, Rockville, Maryland 20850, USA., Bogdanova N; Gynaecology Research Unit, Hannover Medical School, Hannover D-30625, Germany., Bojesen A; Department of Clinical Genetics, Vejle Hospital, Vejle 7100, Denmark., Bojesen SE; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2200, Denmark.; Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev 2730, Denmark.; Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Herlev 2730, Denmark., Bolla MK; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK., Bonanni B; Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia, Milan 20141, Italy., Børresen-Dale AL; Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo N-0310, Norway.; K.G. Jebsen Center for Breast Cancer Research, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo N-0310, Norway., Brauch H; Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart D-70376, Germany.; University of Tübingen, Tübingen 72074, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg 69120, Germany., Brennan P; International Agency for Research on Cancer, Lyon 69008, France., Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg 69120, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ), Heidelberg 69121, Germany., Bruinsma F; Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria 3004, Australia., Brunet J; Genetic Counseling Unit, Hereditary Cancer Program, IDIBGI (Institut d'Investigació Biomèdica de Girona), Catalan Institute of Oncology, Girona 08908, Spain., Buhari SA; Department of Surgery, National University Health System, Singapore 119077, Singapore., Burwinkel B; Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg 69120, Germany.; Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg 69120, Germany., Butzow R; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki 00029 HUS, Finland.; Department of Pathology, Helsinki University Central Hospital, Helsinki 00029, Finland., Buys SS; Department of Medicine, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah 84112, USA., Cai Q; Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA., Caldes T; Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC (El Instituto de Investigación Sanitaria del Hospital Clínico San Carlos), Madrid 28040, Spain., Campbell I; Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, Melbourne, Victoria 3002, Australia., Canniotto R; Cancer Pathology &Prevention, Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo 14263, New York, USA., Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg 69121, Germany.; University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany., Chiquette J; Unité de recherche en santé des populations, Centre des maladies du sein Deschênes-Fabia, Centre de recherche FRSQ du Centre hospitalier affilié universitaire de Québec, Québec City, Québec G1J 1Z4, Canada., Choi JY; Cancer Research Institute, Seoul National University, Seoul 08826, Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea., Claes KB; Center for Medical Genetics, Ghent University, Ghent 9000, Belgium., Cook LS; Division of Epidemiology and Biostatistics, Department of Internal Medicine, University of New Mexico, Albuquerque, New Mexico 87131, USA., Cox A; Sheffield Cancer Research, Department of Oncology, University of Sheffield, Sheffield S10 2TN, UK., Cramer DW; Harvard HT Chan School of Public Health, Boston, Massachusetts 02115, USA.; Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA., Cross SS; Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield S10 2TN, UK., Cybulski C; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin 70-115, Poland., Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm SE-171 77, Sweden., Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA., Damiola F; INSERM U1052, CNRS UMR5286, Université Lyon, Centre de Recherche en Cancérologie de Lyon, Lyon 69373, France., Dansonka-Mieszkowska A; Department of Pathology and Laboratory Diagnostics the Maria Sklodowska Curie Memorial Cancer Center and Institute of Oncology, Warsaw 44-101, Poland., Darabi H; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm SE-171 77, Sweden., Dennis J; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK., Devilee P; Department of Pathology, Leiden University Medical Center, Leiden 2333, The Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden 2333, The Netherlands., Diez O; Oncogenetics Group, University Hospital Vall d'Hebron, Vall d'Hebron Institute of Oncology (VHIO) and Universitat Autònoma de Barcelona, Barcelona 08035, Spain., Doherty JA; Department of Community and Family Medicine, Section of Biostatistics &Epidemiology, The Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire 03755, USA., Domchek SM; Department of Medicine, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA., Dorfling CM; Department of Genetics, University of Pretoria, Pretoria 0083, South Africa., Dörk T; Gynaecology Research Unit, Hannover Medical School, Hannover D-30625, Germany., Dumont M; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Québec G1V 4G2, Canada., Ehrencrona H; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala 751 05, Sweden.; Department of Clinical Genetics, Lund University Hospital, Lund 221 00, Sweden., Ejlertsen B; Department of Oncology, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark., Ellis S; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK., Engel C; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, 04107 Leipzig, Germany., Lee E; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA., Evans DG; Genomic Medicine, Manchester Academic Health Sciences Centre, Institute of Human Development, Manchester University, Central Manchester University Hospitals NHS Foundation Trust, Manchester M13 9PL, UK., Fasching PA; University Hospital Erlangen, Department of Gynecology and Obstetrics, Friedrich-Alexander-University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen 91054, Germany.; University of California at Los Angeles, David Geffen School of Medicine, Department of Medicine, Division of Hematology and Oncology, Los Angeles California 90095, USA., Feliubadalo L; Molecular Diagnostic Unit, Hereditary Cancer Program, IDIBELL (Bellvitge Biomedical Research Institute),Catalan Institute of Oncology, Barcelona 08908, Spain., Figueroa J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892, USA., Flesch-Janys D; Institute for Medical Biometrics and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.; Department of Cancer Epidemiology, Clinical Cancer Registry, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany., Fletcher O; Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London SW3 6JB, UK.; Division of Breast Cancer Research, The Institute of Cancer Research, London SW7 3RP, UK., Flyger H; Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital, 2730 Herlev, Denmark., Foretova L; Masaryk Memorial Cancer Institute and Medical Faculty MU, 625 00 Brno, Czech Republic., Fostira F; Molecular Diagnostics Laboratory, (INRASTES) Institute of Nuclear and Radiological Sciences and Technology, National Centre for Scientific Research 'Demokritos', Aghia Paraskevi Attikis, Athens 153 10, Greece., Foulkes WD; Program in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, Montreal, Montreal, Quebec H2W 1S6, Canada., Fridley BL; Biostatistics and Informatics Shared Resource, University of Kansas Medical Center, Kansas City, Kansas 66160, USA., Friedman E; Susanne Levy Gertner Oncogenetics Unit, Sheba Medical Center, Tel-Hashomer 52621, Israel., Frost D; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK., Gambino G; Section of Genetic Oncology, Department of Laboratory Medicine, University and University Hospital of Pisa, Pisa 56126, Italy., Ganz PA; UCLA Schools of Medicine and Public Health, Division of Cancer Prevention &Control Research, Jonsson Comprehensive Cancer Center, Los Angeles, California 90024, USA., Garber J; Cancer Risk and Prevention Clinic, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA., García-Closas M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892, USA.; Division of Genetics and Epidemiology, The Institute of Cancer Research, London SW7 3RP, UK., Gentry-Maharaj A; Women's Cancer, UCL EGA Institute for Women's Health, London WC1E 6AU, UK., Ghoussaini M; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK., Giles GG; Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria 3004, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria 3010, Australia., Glasspool R; Cancer Research UK Clinical Trials Unit, The Beatson West of Scotland Cancer Centre, Glasgow G12 0YN, UK., Godwin AK; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas 66160, USA., Goldberg MS; Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University, Montreal, Québec H3A 1A1, Canada.; Department of Medicine, McGill University, Montreal, Québec H3A 1A1, Canada., Goldgar DE; Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA., González-Neira A; Human Cancer Genetics Program, Spanish National Cancer Research Centre, Madrid E-28029, Spain., Goode EL; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55902, USA., Goodman MT; Cancer Prevention and Control, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA.; Community and Population Health Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA., Greene MH; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20892, USA., Gronwald J; Department of Genetics and Pathology, Pomeranian Medical University, 70-204 Szczecin, Poland., Guénel P; Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, 94805 Villejuif, France.; University Paris-Sud, 91405 Villejuif, France., Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA., Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm SE-171 77, Sweden., Hallberg E; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55902, USA., Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg 69120, Germany., Hansen TV; Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark., Harrington PA; Department of Oncology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge CB1 8RN, UK., Hartman M; Department of Surgery, National University Health System, Singapore 119077, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore Singapore 119077, Singapore., Hassan N; Breast Cancer Research Unit, Cancer Research Institute, University Malaya Medical Centre, 50603 Kuala Lumpur, Malaysia.; Cancer Research Initiatives Foundation, Subang Jaya, 47500 Selangor, Malaysia., Healey S; QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia., Heitz F; Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte, 45136 Essen, Germany.; Department of Gynecology and Gynecologic Oncology, Dr Horst Schmidt Kliniken Wiesbaden, 65199 Wiesbaden, Germany., Herzog J; Clinical Cancer Genetics, for the City of Hope Clinical Cancer Genetics Community Research Network, Duarte California 91010, USA., Høgdall E; Molecular Unit, Department of Pathology, Herlev Hospital, University of Copenhagen, 2730 Copenhagen, Denmark.; Department of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, DK-2100 Copenhagen, Denmark., Høgdall CK; Department of Gynecology, Rigshospitalet, University of Copenhagen, 2100 Copenhagen, Denmark., Hogervorst FB; Family Cancer Clinic, Netherlands Cancer Institute, 1006 Amsterdam, The Netherlands., Hollestelle A; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, 3015 Rotterdam, The Netherlands., Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria 3010, Australia., Hulick PJ; Center for Medical Genetics, NorthShore University Health System, Evanston, Illinois, 60201, USA., Huzarski T; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin 70-115, Poland., Imyanitov EN; N.N. Petrov Institute of Oncology, St Petersburg 197758, Russia., Isaacs C; Lombardi Comprehensive Cancer Center, Georgetown University, Washington District of Columbia 20057, USA., Ito H; Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Aichi 464-8681, Japan., Jakubowska A; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin 70-115, Poland., Janavicius R; State Research Institute Centre for Innovative Medicine, LT-01102 Vilnius, Lithuania., Jensen A; Department of Gynecology, Rigshospitalet, University of Copenhagen, 2100 Copenhagen, Denmark., John EM; Department of Epidemiology, Cancer Prevention Institute of California, Fremont, California 94538, USA., Johnson N; Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London SW3 6JB, UK.; Division of Breast Cancer Research, The Institute of Cancer Research, London SW7 3RP, UK., Kabisch M; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg 69120, Germany., Kang D; Cancer Research Institute, Seoul National University, Seoul 08826, Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea.; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul 08826, Korea., Kapuscinski M; Centre for Epidemiology and Biostatistics, University of Melbourne, Melbourne, Victoria 3010, Australia., Karlan BY; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA., Khan S; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki 00029 HUS, Finland., Kiemeney LA; Radboud University Medical Centre, Radboud Institute for Health Sciences, 6500 Nijmegen, The Netherlands., Kjaer SK; Department of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, DK-2100 Copenhagen, Denmark.; Department of Gynecology, Rigshospitalet, University of Copenhagen, 2100 Copenhagen, Denmark., Knight JA; Prosserman Centre for Health Research, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada.; Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario M5T 3M7, Canada., Konstantopoulou I; Molecular Diagnostics Laboratory, (INRASTES) Institute of Nuclear and Radiological Sciences and Technology, National Centre for Scientific Research 'Demokritos', Aghia Paraskevi Attikis, Athens 153 10, Greece., Kosma VM; Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, 70210 Kuopio, Finland.; Cancer Center, Kuopio University Hospital, 70210 Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, 70210 Kuopio, Finland., Kristensen V; Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo N-0310, Norway.; K.G. Jebsen Center for Breast Cancer Research, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo N-0310, Norway.; Department of Clinical Molecular Biology, Oslo University Hospital, University of Oslo, 1478 Oslo, Norway., Kupryjanczyk J; Department of Pathology and Laboratory Diagnostics the Maria Sklodowska Curie Memorial Cancer Center and Institute of Oncology, Warsaw 44-101, Poland., Kwong A; The Hong Kong Hereditary Breast Cancer Family Registry, Cancer Genetics Center, Hong Kong Sanatorium and Hospital, Hong Kong, China.; Department of Surgery, The University of Hong Kong, Hong Kong, China., de la Hoya M; Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC (El Instituto de Investigación Sanitaria del Hospital Clínico San Carlos), Madrid 28040, Spain., Laitman Y; Susanne Levy Gertner Oncogenetics Unit, Sheba Medical Center, Tel-Hashomer 52621, Israel., Lambrechts D; Vesalius Research Center, VIB, 3000 Leuven, Belgium.; Laboratory for Translational Genetics, Department of Oncology, University of Leuven, 3000 Leuven, Belgium., Le N; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA., De Leeneer K; Center for Medical Genetics, Ghent University, Ghent 9000, Belgium., Lester J; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA., Levine DA; Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York 10065, USA., Li J; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm SE-171 77, Sweden., Lindblom A; Department of Molecular Medicine and Surgery, Karolinska Institutet, SE-171 77 Stockholm, Sweden., Long J; Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA., Lophatananon A; Division of Health Sciences, Warwick Medical School, Warwick University, Coventry CV4 7AL, UK., Loud JT; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20892, USA., Lu K; Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Lubinski J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin 70-115, Poland., Mannermaa A; Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, 70210 Kuopio, Finland.; Cancer Center, Kuopio University Hospital, 70210 Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, 70210 Kuopio, Finland., Manoukian S; Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale Tumori (INT), 20133 Milan, Italy., Le Marchand L; University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA., Margolin S; Department of Oncology - Pathology, Karolinska Institutet, SE-171 77 Stockholm, Sweden., Marme F; Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg 69120, Germany.; National Center for Tumour Diseases, University of Heidelberg, 69117 Heidelberg, Germany., Massuger LF; Department of Gynaecology, Radboud University Medical Centre, 6500 Nijmegen, The Netherlands., Matsuo K; Department of Preventive Medicine, Kyushu University Faculty of Medical Sciences, Fukuoka 812-8582, Japan., Mazoyer S; INSERM U1052, CNRS UMR5286, Université Lyon, Centre de Recherche en Cancérologie de Lyon, Lyon 69373, France., McGuffog L; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK., McLean C; Anatomical Pathology, The Alfred Hospital, Melbourne, Victoria 3004, Australia., McNeish I; Institute of Cancer Sciences, University of Glasgow, Wolfson Wohl Cancer Research Centre, Beatson Institute for Cancer Research, Glasgow G61 1BD, UK., Meindl A; Division of Gynaecology and Obstetrics, Technische Universität München, 81675 Munich, Germany., Menon U; Women's Cancer, UCL EGA Institute for Women's Health, London WC1E 6AU, UK., Mensenkamp AR; Department of Human Genetics, Radboud University Medical Centre, 6500 Nijmegen, The Netherlands., Milne RL; Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria 3004, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria 3010, Australia., Montagna M; Immunology and Molecular Oncology Unit, Instituto Oncologico Veneto IOV, IRCCS, 35128 Padua, Italy., Moysich KB; Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York 14263, USA., Muir K; Division of Health Sciences, Warwick Medical School, Warwick University, Coventry CV4 7AL, UK.; Institute of Population Health, University of Manchester, Manchester M13 9PL, UK., Mulligan AM; Laboratory Medicine Program, University Health Network, Toronto, Ontario M5G 1L7, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Nathanson KL; Department of Medicine, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA., Ness RB; The University of Texas School of Public Health, Houston, Texas 77030, USA., Neuhausen SL; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California 91010, USA., Nevanlinna H; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki 00029 HUS, Finland., Nord S; K.G. Jebsen Center for Breast Cancer Research, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo N-0310, Norway., Nussbaum RL; Department of Medicine and Genetics, University of California, San Francisco, California 94143, USA., Odunsi K; Department of Gynecological Oncology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA., Offit K; Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York 10065, USA., Olah E; Department of Molecular Genetics, National Institute of Oncology, 1122 Budapest, Hungary., Olopade OI; Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center, Chicago, Illinois 60637, USA., Olson JE; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55902, USA., Olswold C; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55902, USA., O'Malley D; The Ohio State University and the James Cancer Center, Columbus, Ohio 43210, USA., Orlow I; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York 10017, USA., Orr N; Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London SW3 6JB, UK., Osorio A; Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Centre (CNIO), 28019 Madrid, Spain.; Biomedical Network on Rare Diseases (CIBERER), 28029 Madrid, Spain., Park SK; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea.; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul 08826, Korea.; Department of Surgery, Seoul National University College of Medicine, Seoul, 03080 Korea., Pearce CL; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA., Pejovic T; Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, Oregon 97239, USA.; Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon 97239, USA., Peterlongo P; IFOM, The FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, 16 20139 Milan, Italy., Pfeiler G; Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, 1090 Vienna, Austria., Phelan CM; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida 33606, USA., Poole EM; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.; Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, Massachusetts 02115, USA., Pylkäs K; Laboratory of Cancer Genetics and Tumour Biology, Northern Finland Laboratory Centre NordLab, FI-90014 Oulu, Finland.; Laboratory of Cancer Genetics and Tumour Biology, Department of Clinical Chemistry and Biocenter Oulu, University of Oulu, FI-90014 Oulu, Finland., Radice P; Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale dei Tumori (INT), 20133 Milan, Italy., Rantala J; Department of Clinical Genetics, Karolinska University Hospital, 171 76 Stockholm, Sweden., Rashid MU; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg 69120, Germany.; Department of Basic Sciences, Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH &RC), Lahore 54000, Pakistan., Rennert G; Clalit National Israeli Cancer Control Center and Department of Community Medicine and Epidemiology, Carmel Medical Center and B. Rappaport Faculty of Medicine, Haifa 34362, Israel., Rhenius V; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK., Rhiem K; Centre of Familial Breast and Ovarian Cancer, Department of Gynaecology and Obstetrics and Centre for Integrated Oncology (CIO), Center for Molecular Medicine Cologne (CMMC), University Hospital of Cologne, 50931 Cologne, Germany., Risch HA; Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, Connecticut 06510, USA., Rodriguez G; Division of Gynecologic Oncology, NorthShore University HealthSystem, Evanston, Illinois 60201, USA., Rossing MA; Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.; Department of Epidemiology, University of Washington, Seattle, Washington 98109, USA., Rudolph A; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg 69121, Germany., Salvesen HB; Department of Gynecology and Obstetrics, Haukeland University Hospital, 5021 Bergen, Norway.; Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen, N-5020 Bergen, Norway., Sangrajrang S; National Cancer Institute, Bangkok 10400, Thailand., Sawyer EJ; Research Oncology, Guy's Hospital, King's College London, London SE1 9RT, UK., Schildkraut JM; Department of Community and Family Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA.; Cancer Control and Population Sciences, Duke Cancer Institute, Durham, North Carolina 27710, USA., Schmidt MK; Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, 1066 CX Amsterdam, The Netherlands., Schmutzler RK; Division of Molecular Gyneco-Oncology, Department of Gynaecology and Obstetrics, University Hospital of Cologne, 50676 Cologne, Germany.; Center for Integrated Oncology, University Hospital of Cologne, 50676 Cologne, Germany.; Center for Molecular Medicine, University Hospital of Cologne, 50676 Cologne, Germany.; Center of Familial Breast and Ovarian Cancer, University Hospital of Cologne, 50676 Cologne, Germany., Sellers TA; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida 33606, USA., Seynaeve C; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, 3015 Rotterdam, The Netherlands., Shah M; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK., Shen CY; Taiwan Biobank, Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan.; School of Public Health, China Medical University, Taichung 404, Taiwan., Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA., Sieh W; Department of Health Research and Policy - Epidemiology, Stanford University School of Medicine, Stanford California 94305, USA., Singer CF; Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, 1090 Vienna, Austria., Sinilnikova OM; Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices Civils de Lyon - Centre Léon Bérard, Lyon 69008, France.; INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon 69003, France., Slager S; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55902, USA., Song H; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK., Soucy P; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Québec G1V 4G2, Canada., Southey MC; Department of Pathology, University of Melbourne, Parkville, Victoria 3010, Australia., Stenmark-Askmalm M; Department of Clinical Genetics, Lund University Hospital, Lund 221 00, Sweden.; Division of Clinical Genetics, Department of Clinical and Experimental Medicine, Linköping University, 581 83 Linköping, Sweden., Stoppa-Lyonnet D; Institut Curie, Department of Tumour Biology, Paris, France; Institut Curie, INSERM U830, 75248 Paris, France.; Université Paris Descartes, Sorbonne Paris Cité, 75270 Paris, France., Sutter C; Institute of Human Genetics, Department of Human Genetics, University Hospital Heidelberg, 69120 Heidelberg, Germany., Swerdlow A; Division of Breast Cancer Research, The Institute of Cancer Research, London SW7 3RP, UK.; Division of Genetics and Epidemiology, The Institute of Cancer Research, London SW7 3RP, UK., Tchatchou S; Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada., Teixeira MR; Department of Genetics, Portuguese Oncology Institute, Porto 4200-072, Portugal.; Biomedical Sciences Institute (ICBAS), Porto University, Porto 4099-002, Portugal., Teo SH; Breast Cancer Research Unit, Cancer Research Institute, University Malaya Medical Centre, 50603 Kuala Lumpur, Malaysia.; Cancer Research Initiatives Foundation, Subang Jaya, 47500 Selangor, Malaysia., Terry KL; Harvard HT Chan School of Public Health, Boston, Massachusetts 02115, USA.; Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA., Terry MB; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York 10027, USA., Thomassen M; Department of Clinical Genetics, Odense University Hospital, 5000 Odense C, Denmark., Tibiletti MG; UO Anatomia Patologica, Ospedale di Circolo-Università dell'Insubria, 21100 Varese, Italy., Tihomirova L; Latvian Biomedical Research and Study Centre, Riga LV-1067, Latvia., Tognazzo S; Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV - IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico), 64 - 35128 Padua, Italy., Toland AE; Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio 43210, USA., Tomlinson I; Wellcome Trust Centre for Human Genetics and Oxford Biomedical Research Centre, University of Oxford, Oxford OX3 7BN, UK., Torres D; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg 69120, Germany.; Institute of Human Genetics, Pontificia Universidad Javeriana, Cra. 7 #40-62 Bogota, Colombia., Truong T; Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, 94805 Villejuif, France.; University Paris-Sud, 91405 Villejuif, France., Tseng CC; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA., Tung N; Department of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA., Tworoger SS; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.; Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, Massachusetts 02115, USA., Vachon C; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55902, USA., van den Ouweland AM; Department of Clinical Genetics, Erasmus University Medical Center, 3015 CE Rotterdam, The Netherlands., van Doorn HC; Department of Gynecology, Family Cancer Clinic, Erasmus MC Cancer Institute, 3015 CE Rotterdam, The Netherlands., van Rensburg EJ; Department of Genetics, University of Pretoria, Pretoria 0083, South Africa., Van't Veer LJ; Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, 1066 CX Amsterdam, The Netherlands., Vanderstichele A; Division of Gynecological Oncology, Department of Oncology, University Hospitals Leuven, B-3000 Leuven, Belgium., Vergote I; Division of Gynecological Oncology, Department of Oncology, University Hospitals Leuven, B-3000 Leuven, Belgium., Vijai J; Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York 10065, USA., Wang Q; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK., Wang-Gohrke S, Weitzel JN; Clinical Cancer Genetics, for the City of Hope Clinical Cancer Genetics Community Research Network, Duarte California 91010, USA., Wentzensen N; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda Maryland 20892, USA., Whittemore AS; Department of Health Research and Policy - Epidemiology, Stanford University School of Medicine, Stanford California 94305, USA., Wildiers H; Multidisciplinary Breast Center, Department of General Medical Oncology, University Hospitals Leuven, B-3000 Leuven, Belgium., Winqvist R; Laboratory of Cancer Genetics and Tumour Biology, Northern Finland Laboratory Centre NordLab, FI-90014 Oulu, Finland.; Laboratory of Cancer Genetics and Tumour Biology, Department of Clinical Chemistry and Biocenter Oulu, University of Oulu, FI-90014 Oulu, Finland., Wu AH; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA., Yannoukakos D; Molecular Diagnostics Laboratory, IRRP, National Centre for Scientific Research 'Demokritos', Athens 153 10, Greece., Yoon SY; Cancer Research Initiatives Foundation, Sime Darby Medical Centre, 47500 Subang Jaya, Malaysia.; University Malaya Cancer Research Institute, Faculty of Medicine, University Malaya Medical Centre, University Malaya, 59100 Kuala Lumpur, Malaysia., Yu JC; Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, 114 Taiwan., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA., Zheng Y; Shanghai Center for Disease Control and Prevention, Shanghai, China., Khanna KK; QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia., Simard J; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Québec G1V 4G2, Canada., Monteiro AN; Cancer Epidemiology Program, Division of Population Sciences, H. Lee Moffitt Cancer Center &Research Institute, Tampa, Florida 33612, USA., French JD; QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia., Couch FJ; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55902, USA.; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA., Freedman ML; Department of Medical Oncology, The Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA., Easton DF; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK.; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK., Dunning AM; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK., Pharoah PD; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK., Edwards SL; QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia., Chenevix-Trench G; QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia., Antoniou AC; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK., Gayther SA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA.

مؤلفون مشاركون: GEMO Study Collaborators, EMBRACE, Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON), KConFab Investigators, Australian Ovarian Cancer Study Group

المصدر: Nature communications [Nat Commun] 2016 Sep 07; Vol. 7, pp. 12675. Date of Electronic Publication: 2016 Sep 07.

نوع المنشور: Adaptive Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Alleles* , Genetic Predisposition to Disease* , Polymorphism, Single Nucleotide*, Breast Neoplasms/*genetics , Chromosomes, Human, Pair 19/*genetics , Ovarian Neoplasms/*genetics, Asian People/genetics ; Black People/genetics ; Female ; Genome-Wide Association Study ; Genotype ; Humans ; RNA, Messenger/genetics ; RNA, Messenger/metabolism

المؤلفون: Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA.; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Kuchenbaecker KB; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Michailidou K; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Mendoza-Fandino GA; Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA., Nord S; Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, N-0310 Oslo, Norway., Lilyquist J; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Olswold C; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Hallberg E; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Agata S; Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV-IRCCS, 20133 Padua, Italy., Ahsan H; Department of Health Studies, The University of Chicago, Chicago, Illinois 60637, USA.; Comprehensive Cancer Center, The University of Chicago, Chicago, Illinois 60637, USA.; Departments of Medicine and Human Genetics, The University of Chicago, Chicago, Illinois 60637, USA., Aittomäki K; Department of Clinical Genetics, Helsinki University Central Hospital, 00029 Helsinki, Finland., Ambrosone C; Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York 14263, USA., Andrulis IL; Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5.; Departments of Molecular Genetics and Laboratory Medicine and Pathobiology, University of Toronto, Ontario, Canada M5B 1W8., Anton-Culver H; Department of Epidemiology, University of California Irvine, Irvine, California, 92697, USA., Arndt V; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Arun BK; University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Arver B; Department of Oncology, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Barile M; Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia, 20141 Milan, Italy., Barkardottir RB; Department of Pathology, Landspitali University Hospital and University of Iceland School of Medicine, 101 Reykjavik, Iceland., Barrowdale D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Beckmann L; Institute for Quality and Efficiency in Health Care (IQWiG), 50670 Cologne, Germany., Beckmann MW; University Breast Center Franconia, Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, 91054 Erlangen, Germany., Benitez J; Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Centre (CNIO), 28029 Madrid, Spain.; Genotyping Unit (CeGen), Human Cancer Genetics Program, Spanish National Cancer Centre (CNIO), 28029 Madrid, Spain.; Biomedical Network on Rare Diseases (CIBERER), 28029 Madrid, Spain., Blank SV; NYU Women's Cancer Program, New York University School of Medicine, New York, New York 10016, USA., Blomqvist C; Department of Oncology, University of Helsinki and Helsinki University Central Hospital, FI-00029 Helsinki, Finland., Bogdanova NV; Department of Radiation Oncology, Hannover Medical School, 30625 Hannover, Germany., Bojesen SE; Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, 2730 Herlev, Denmark., Bolla MK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Bonanni B; Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia, 20141 Milan, Italy., Brauch H; Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, 70376 Stuttgart, Germany.; University of Tübingen 72074 Tübingen, Germany., Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), 69120 Heidelberg, Germany., Burwinkel B; Department of Obstetrics and Gynecology, University of Heidelberg, 69120 Heidelberg, Germany., Buys SS; Department of Medicine, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City Utah 84112, USA., Caldes T; Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC, Madrid 28040, Spain., Caligo MA; Section of Genetic Oncology, Department of Laboratory Medicine, University and University Hospital of Pisa, I-56126 Pisa, Italy., Canzian F; Genomic Epidemiology Group, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Carpenter J; Australian Breast Cancer Tissue Bank, Westmead Millennium Institute, University of Sydney, Sydney, New South Wales 2145, Australia., Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20850, USA., Chung WK; Departments of Pediatrics and Medicine, Columbia University, New York, New York 10032, USA., Claes KB; Center for Medical Genetics, Ghent University, 9000 Ghent, Belgium., Cox A; Sheffield Cancer Research Centre, Department of Oncology, University of Sheffield, Sheffield S10 2RX, UK., Cross SS; Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Cunningham JM; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA., Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-17177 Stockholm, Sweden., Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA., Damiola F; INSERM U1052, CNRS UMR5286, Université Lyon, Centre de Recherche en Cancérologie de Lyon, 69373 Lyon, France., Darabi H; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-17177 Stockholm, Sweden., de la Hoya M; Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC, Madrid 28040, Spain., Devilee P; Department of Human Genetics and Department of Pathology, Leiden University Medical Center, Leiden 2333 ZC, The Netherlands., Diez O; Oncogenetics Group, University Hospital Vall d'Hebron, Vall d'Hebron Institute of Oncology (VHIO) and Universitat Autònoma de Barcelona, 08035 Barcelona, Spain., Ding YC; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California 91010, USA., Dolcetti R; Cancer Bioimmunotherapy Unit, CRO Aviano National Cancer Institute, 33081 Aviano , Italy., Domchek SM; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Pennsylvania 19104, USA., Dorfling CM; Department of Genetics, University of Pretoria, Pretoria 0007, South Africa., Dos-Santos-Silva I; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK., Dumont M; Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Québec and Laval University, Quebec City, Quebec, Canada G1V 4G2., Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK., Eccles DM; Faculty of Medicine, University of Southampton, University Hospital Southampton, Southampton, Hampshire SO16 6YD, UK., Ehrencrona H; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala SE-751 85, Sweden.; Department of Clinical Genetics, Lund University Hospital, SE-22185 Lund, Sweden., Ekici AB; Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, 91054 Erlangen, Germany.; Comprehensive Cancer Center -EMN, 91054 Erlangen, Germany., Eliassen H; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA., Ellis S; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Fasching PA; University Breast Center Franconia, Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, 91054 Erlangen, Germany., Figueroa J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20850, USA., Flesch-Janys D; Department of Cancer Epidemiology/Clinical Cancer Registry and Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, 20246 Hamburg, Germany., Försti A; Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.; Center for Primary Health Care Research, Lund University, SE-221 00 Malmö, Sweden., Fostira F; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Aghia Paraskevi Attikis, 15310 Athens, Greece., Foulkes WD; Program in Cancer Genetics, McGill University, Montreal, Quebec, Canada H3A 0G4., Friebel T; University of, Philadelphia, Pennsylvania 19104, USA., Friedman E; Susanne Levy Gertner Oncogenetics Unit, Sheba Medical Center, Tel-Hashomer 52621, Israel., Frost D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Gabrielson M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-17177 Stockholm, Sweden., Gammon MD; Department of Epidemiology, University of, Chapel Hill, North Carolina 27599-7400, USA., Ganz PA; UCLA Schools of Medicine and Public Health, Division of Cancer Prevention and Control Research, Jonsson Comprehensive Cancer Center, Los Angeles, California 90095-6900, USA., Gapstur SM; Epidemiology Research Program, American Cancer Society, Atlanta, Georgia 30303, USA., Garber J; Cancer Risk and Prevention Clinic, Dana Farber Cancer Institute, Boston, Massachusetts 02215, USA., Gaudet MM; Epidemiology Research Program, American Cancer Society, Atlanta, Georgia 30303, USA., Gayther SA; Department of Biomedical Sciences, Cedars Sinai Medical Center, Los Angeles, California 90048, USA., Gerdes AM; Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark., Ghoussaini M; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK., Giles GG; Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria 3010, Australia., Glendon G; Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5., Godwin AK; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, 66205, USA., Goldberg MS; Department of Medicine, McGill University, Montreal, Quebec, Canada H3G 2M1.; Division of Clinical Epidemiology, McGill University Health Centre, Royal Victoria Hospital, Montreal, Quebec, Canada H4A 3J1., Goldgar DE; Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA., González-Neira A; Human Genotyping-CEGEN Unit, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain., Greene MH; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20850-9772, USA., Gronwald J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Guénel P; Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer, 70-115 Villejuif, France., Gunter M; Department of of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, SW7 2AZ, UK., Haeberle L; University Breast Center Franconia, Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, 91054 Erlangen, Germany., Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA., Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Hansen TV; Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark., Hart S; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Healey S; Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia., Heikkinen T; Department of Obstetrics and Gynecology, University of Heidelberg, 69120 Heidelberg, Germany.; Helsinki University Central Hospital, FI-00029 Helsinki, Finland., Henderson BE; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA., Herzog J; Clinical Cancer Genetics, for the City of Hope Clinical Cancer Genetics Community Research Network, Duarte, California 91010, USA., Hogervorst FB; Family Cancer Clinic, Netherlands Cancer Institute, Amsterdam 1000 BE, The Netherlands., Hollestelle A; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam 3008 AE, The Netherlands., Hooning MJ; Department of Medical Oncology, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam 3008 AE, The Netherlands., Hoover RN; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20850, USA., Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria 3010, Australia., Humphreys K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-17177 Stockholm, Sweden., Hunter DJ; Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA., Huzarski T; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Imyanitov EN; N.N. Petrov Institute of Oncology, 197758 St Petersburg, Russia., Isaacs C; Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA., Jakubowska A; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., James P; Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Victoria 8006, Australia.; Department of Oncology, The University of Melbourne, Melbourne, Victoria 8006, Australia., Janavicius R; State Research Institute Centre for Innovative Medicine, LT-08661 Vilnius, Lithuania., Jensen UB; Department of Clinical Genetics, Aarhus University Hospital, 8200 Aarhus N, Denmark., John EM; Department of Epidemiology, Cancer Prevention Institute of California, Fremont, California 94538, USA., Jones M; Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton SM2 5NG, UK., Kabisch M; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Kar S; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK., Karlan BY; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, 90048, USA., Khan S; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, FI-00029 Helsinki, Finland., Khaw KT; Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge CB1 8RN, UK., Kibriya MG; Department of Health Studies, The University of Chicago, Chicago, Illinois 60637, USA., Knight JA; Prosserman Centre for Health Research, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5., Ko YD; Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus, 53113 Bonn, Germany., Konstantopoulou I; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Aghia Paraskevi Attikis, 15310 Athens, Greece., Kosma VM; School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, FI-70211 Kuopio, Finland., Kristensen V; Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, N-0310 Oslo, Norway., Kwong A; The Hong Kong Hereditary Breast Cancer Family Registry, Cancer Genetics Center, Hong Kong Sanatorium and Hospital, Hong Kong.; Department of Surgery, The University of Hong Kong, Hong Kong, China., Laitman Y; Susanne Levy Gertner Oncogenetics Unit, Sheba Medical Center, Tel-Hashomer 52621, Israel., Lambrechts D; Vesalius Research Center, VIB, 3000 Leuven, Belgium., Lazaro C; Molecular Diagnostic Unit, Hereditary Cancer Program, IDIBELL-Catalan Institute of Oncology, 08908 Barcelona, Spain., Lee E; Department of Preventive Medicine, University of Southern California, Los Angeles, California 90032, USA., Le Marchand L; Cancer Epidemiology Program, University of Cancer Center, Honolulu, Hawaii 96813, USA., Lester J; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, 90048, USA., Lindblom A; Department of Molecular Medicine and Surgery, Karolinska Institutet, SE-17177 Stockholm, Sweden., Lindor N; Health Sciences Research, Mayo Clinic, Scotsdale, Arizona 85259, USA., Lindstrom S; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard School of Public Health, Boston, Massachusetts 02115, USA., Liu J; Human Genetics Division, Genome Institute of Singapore, Singapore 138672, Singapore., Long J; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA., Lubinski J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Mai PL; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20850-9772, USA., Makalic E; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria 3010, Australia., Malone KE; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.; Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, Washington 98195, USA., Mannermaa A; School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, FI-70211 Kuopio, Finland., Manoukian S; Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), 20133 Milan, Italy., Margolin S; Department of Oncology, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Marme F; Department of Obstetrics and Gynecology, University of Heidelberg, 69120 Heidelberg, Germany., Martens JW; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam 3008 AE, The Netherlands., McGuffog L; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Meindl A; Department of Gynaecology and Obstetrics, Technical University of Munich, 81675 Munich, Germany., Miller A; NRG Oncology Statistics and Data Management Center, Roswell Park Cancer Institute, Buffalo, New York 14263, USA., Milne RL; Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria 3010, Australia., Miron P; Department of Genomics and Genome Sciences, Case Western Reserve University Medical School, Cleveland, Ohio 44106, USA., Montagna M; Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV-IRCCS, 20133 Padua, Italy., Mazoyer S; INSERM U1052, CNRS UMR5286, Université Lyon, Centre de Recherche en Cancérologie de Lyon, 69373 Lyon, France., Mulligan AM; Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada M5B 1W8.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada M5B 1W8., Muranen TA; Department of Obstetrics and Gynecology, University of Heidelberg, 69120 Heidelberg, Germany.; Helsinki University Central Hospital, FI-00029 Helsinki, Finland., Nathanson KL; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Pennsylvania 19104, USA., Neuhausen SL; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California 91010, USA., Nevanlinna H; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, FI-00029 Helsinki, Finland., Nordestgaard BG; Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, 2730 Herlev, Denmark., Nussbaum RL; Invitae Corporation, San Francisco, California 94107, USA., Offit K; Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA., Olah E; Department of Molecular Genetics, National Institute of Oncology, H-1122 Budapest, Hungary., Olopade OI; Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center, Chicago, Illinois 60637, USA., Olson JE; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Osorio A; Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Centre (CNIO), 28029 Madrid, Spain., Park SK; Department of Preventive Medicine and Biomedical Science, Seoul National University College of Medicine and Cancer Research Institute, Seoul National University, 110-799 Seoul, Republic of Korea., Peeters PH; Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht 3508 GA, The Netherlands.; MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London SW7 2AZ, UK., Peissel B; Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), 20133 Milan, Italy., Peterlongo P; IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, 20133 Milan, Italy., Peto J; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK., Phelan CM; Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA., Pilarski R; Divison of Human Genetics, Department of Internal Medicine, The Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, USA., Poppe B; Center for Medical Genetics, Ghent University, 9000 Ghent, Belgium., Pylkäs K; Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Chemistry and Biocenter Oulu, University of Oulu, NordLab Oulu/Oulu University Hospital, FI-90220 Oulu, Finland., Radice P; Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), 20133 Milan, Italy., Rahman N; Section of Cancer Genetics, Institute of Cancer Research, Sutton SM2 5NG, UK., Rantala J; Department of Clinical Genetics, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Rappaport C; Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, A 1090 Vienna, Austria., Rennert G; Clalit National Israeli Cancer Control Center and Department of Community Medicine and Epidemiology, Carmel Medical Center and B. Rappaport Faculty of Medicine, Haifa 34362, Israel., Richardson A; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, 21205, USA., Robson M; Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA., Romieu I; International Agency for Research on Cancer, 69008 Lyon, France., Rudolph A; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Rutgers EJ; Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam 1006 BE, The Netherlands., Sanchez MJ; Escuela Andaluza de Salud Pública. Instituto de Investigación Biosanitaria ibs.GRANADA, Hospitales Universitarios de Granada/Universidad de Granada, 18014 Granada, Spain.; CIBER de Epidemiología y Salud Pública (CIBERESP), Spain., Santella RM; Department of Environmental Health Sciences, Columbia University, New York, New York, 10032, USA., Sawyer EJ; Research Oncology, Division of Cancer Studies, King's College London, Guy's Hospital, London SE1 9RT, UK., Schmidt DF; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria 3010, Australia., Schmidt MK; Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam 1006 BE, The Netherlands., Schmutzler RK; Center for Hereditary Breast and Ovarian Cancer, Medical Faculty, University Hospital Cologne, Cologne 50931, Germany.; Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, 50931 Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, 50931 Cologne, Germany., Schumacher F; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA., Scott R; Division of Genetics, Hunter Area Pathology Service, John Hunter Hospital, Newcastle, New South Wales 2305, Australia., Senter L; Divison of Human Genetics, Department of Internal Medicine, The Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, USA., Sharma P; Department of Hematology and Oncology, University of Kansas Medical Center, Kansas City, Kansas 66205, USA., Simard J; Centre Hospitalier Universitaire de Québec Research Center, Laval University, Quebec City, Quebec, Canada G1V 4G2., Singer CF; Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, A 1090 Vienna, Austria., Sinilnikova OM; INSERM U1052, CNRS UMR5286, Université Lyon, Centre de Recherche en Cancérologie de Lyon, 69373 Lyon, France.; Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices Civils de Lyon-Centre Léon Bérard, 69373 Lyon, France., Soucy P; Centre Hospitalier Universitaire de Québec Research Center, Laval University, Quebec City, Quebec, Canada G1V 4G2., Southey M; Department of Pathology, The University of Melbourne, Melbourne, Victoria, Australia., Steinemann D; Hannover Medical School, 30625 Hannover, Germany., Stenmark-Askmalm M; Division of Clinical Genetics, Department of Clinical and Experimental Medicine, Linköping University, SE-58185 Linköping, Sweden., Stoppa-Lyonnet D; Institut Curie, Department of Tumour Biology, 75248 Paris, France.; Université Paris Descartes, Sorbonne Paris Cité, 75248 Paris, France., Swerdlow A; Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton SM2 5NG, UK., Szabo CI; National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892-2152, USA., Tamimi R; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard School of Public Health, Boston, Massachusetts 02115, USA., Tapper W; Faculty of Medicine, University of Southampton, University Hospital Southampton, Southampton, Hampshire SO16 6YD, UK., Teixeira MR; Department of Genetics, Portuguese Oncology Institute, Porto, 4200-072, Portugal.; Biomedical Sciences Institute (ICBAS), Porto University, 4200-072 Porto, Portugal., Teo SH; Cancer Research Initiatives Foundation, Sime Darby Medical Centre, Subang Jaya 47500, Malaysia.; University Malaya Cancer Research Institute, Faculty of Medicine, University Malaya Medical Centre, University Malaya, Kuala Lumpur 50603, Malaysia., Terry MB; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, 10032, USA., Thomassen M; Department of Clinical Genetics, Odense University Hospital, 5000 Odense C, Denmark., Thompson D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Tihomirova L; Latvian Biomedical Research and Study Centre, LV-1067 Riga, Latvia., Toland AE; Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio, 43210, USA., Tollenaar RA; Department of Surgical Oncology, Leiden University Medical Center, Leiden 2333 ZC, The Netherlands., Tomlinson I; Wellcome Trust Centre for Human Genetics and Oxford Biomedical Research Centre, University of Oxford, Oxford OX3 7BN, UK., Truong T; Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer, 70-115 Villejuif, France., Tsimiklis H; Department of Pathology, The University of Melbourne, Melbourne, Victoria, Australia., Teulé A; Genetic Counseling Unit, Hereditary Cancer Program, IDIBELL-Catalan Institute of Oncology, 08908 Barcelona, Spain., Tumino R; Cancer Registry and Histopathology Unit, 'Civic-M.P. Arezzo' Hospital, 97100 ASP Ragusa, Italy., Tung N; Department of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, 02215, USA., Turnbull C; Section of Cancer Genetics, Institute of Cancer Research, Sutton SM2 5NG, UK., Ursin G; Cancer Registry of Norway, Institute of Population-Based Cancer Research, N-0304 Oslo, Norway., van Deurzen CH; Department of Pathology, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam 3000 CA, The Netherlands., van Rensburg EJ; Department of Genetics, University of Pretoria, Pretoria 0007, South Africa., Varon-Mateeva R; Institute of Human Genetics, Charite Berlin, 13353 Berlin, Germany., Wang Z; Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Gaithersburg, Maryland 20877, USA., Wang-Gohrke S; University Hospital Ulm, 89075 Ulm, , Germany., Weiderpass E; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-17177 Stockholm, Sweden.; Cancer Registry of Norway, Institute of Population-Based Cancer Research, N-0304 Oslo, Norway.; Department of Community Medicine, Faculty of Health Sciences, University of Tromsø-The Arctic University of Norway, 9037 Tromsø, Norway.; Genetic Epidemiology Group, Folkhälsan Research Center, 2016 Helsinki, Finland., Weitzel JN; Clinical Cancer Genetics, for the City of Hope Clinical Cancer Genetics Community Research Network, Duarte, California 91010, USA., Whittemore A; Department of Health Research and Policy-Epidemiology, Stanford University School of Medicine, Stanford, California 94305, USA., Wildiers H; Multidisciplinary Breast Center, Department of General Medical Oncology, University Hospitals, B-3000 Leuven, Belgium., Winqvist R; Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Chemistry and Biocenter Oulu, University of Oulu, NordLab Oulu/Oulu University Hospital, FI-90220 Oulu, Finland., Yang XR; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA., Yannoukakos D; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Aghia Paraskevi Attikis, 15310 Athens, Greece., Yao S; Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York 14263, USA., Zamora MP; Servicio de Oncología Médica, Hospital Universitario La Paz, 28046 Madrid, Spain., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA., Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-17177 Stockholm, Sweden., Kraft P; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard School of Public Health, Boston, Massachusetts 02115, USA.; Department of Biostatistics, Harvard School Of Public Health, Boston, Massachusetts 02115, USA., Vachon C; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Slager S; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Chenevix-Trench G; Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia., Pharoah PD; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK., Monteiro AA; Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA., García-Closas M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20850, USA., Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Antoniou AC; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.

المصدر: Nature communications [Nat Commun] 2016 Apr 27; Vol. 7, pp. 11375. Date of Electronic Publication: 2016 Apr 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Breast Neoplasms/*genetics , Genetic Predisposition to Disease/*genetics , Genome-Wide Association Study/*methods , Receptors, Estrogen/*genetics, BRCA1 Protein/genetics ; Chromosomes, Human, Pair 2/genetics ; Cyclophilins/genetics ; Female ; Genotype ; Heterozygote ; Humans ; Mutation ; Polymorphism, Single Nucleotide ; Risk Factors ; tRNA Methyltransferases