المؤلفون: Guo YJ; Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research, International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China., Yao JJ; Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research, International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China., Guo ZZ; Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research, International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China., Ding M; Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research, International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China., Zhang KL; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China., Shen QH; Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research, International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China., Li Y; Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research, International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China., Yu SF; Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research, International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China., Wan T; Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research, International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China., Xu FP; Guandong Provincial hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China., Wang Y; Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research, International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China., Qi XX; Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research, International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China., Wu JJ; Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research, International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China., Chen JX; Beijing University of Chinese Medicine, Beijing, 100029, China. cjx@bucm.edu.cn., Liu ZQ; Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research, International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China. liuzq@gzucm.edu.cn.; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China. liuzq@gzucm.edu.cn., Lu LL; Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research, International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China. lllu@gzucm.edu.cn.

المصدر: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2024 Jun; Vol. 45 (6), pp. 1224-1236. Date of Electronic Publication: 2024 Mar 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE

مواضيع طبية MeSH: Aconitine* , Cardiotoxicity*/metabolism , Cardiotoxicity*/etiology , Histone Deacetylases*/metabolism , AMP-Activated Protein Kinases*/metabolism, Animals ; Mice ; Male ; Humans ; Aconitum/chemistry ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/metabolism ; Drugs, Chinese Herbal/pharmacology

المؤلفون: Xiao Z; Department of Obstetrics, Yongchuan Hospital of Chongqing Medical University, Chongqing, 402160, People's Republic of China., Liu X; Department of Obstetrics, Yongchuan Hospital of Chongqing Medical University, Chongqing, 402160, People's Republic of China., Luan X; Chongqing Key Laboratory of Maternal and Fetal Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People's Republic of China., Duan R; Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, Youyi Road, Yuzhong District, Chongqing, 400016, People's Republic of China., Peng W; Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, Youyi Road, Yuzhong District, Chongqing, 400016, People's Republic of China., Tong C; Chongqing Key Laboratory of Maternal and Fetal Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People's Republic of China., Qiao J; Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, Youyi Road, Yuzhong District, Chongqing, 400016, People's Republic of China. 170216384@qq.com., Qi H; Chongqing Key Laboratory of Maternal and Fetal Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People's Republic of China. qihongbocy@gmail.com.; Women and Children's Hospital of Chongqing Medical University, Chongqing, 401147, People's Republic of China. qihongbocy@gmail.com.

المصدر: Scientific reports [Sci Rep] 2024 May 27; Vol. 14 (1), pp. 12051. Date of Electronic Publication: 2024 May 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Trophoblasts*/metabolism , Glucose*/metabolism , AMP-Activated Protein Kinases*/metabolism , Glucose Transporter Type 3*/metabolism , Glucose Transporter Type 3*/genetics , Diabetes, Gestational*/metabolism , Signal Transduction*, Animals ; Female ; Pregnancy ; Mice ; Placenta/metabolism ; Aminoimidazole Carboxamide/analogs & derivatives ; Aminoimidazole Carboxamide/pharmacology ; Ribonucleotides/pharmacology

المؤلفون: Liang Z; Department of Biological Sciences, Wayne State University, Detroit, MI, USA., Ralph-Epps T; Department of Biological Sciences, Wayne State University, Detroit, MI, USA., Schmidtke MW; Department of Biological Sciences, Wayne State University, Detroit, MI, USA., Lazcano P; Department of Biological Sciences, Wayne State University, Detroit, MI, USA., Denis SW; Laboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology and Metabolism Institute, Amsterdam, The Netherlands.; Amsterdam Cardiovascular Sciences Institute, Amsterdam, The Netherlands.; Emma Center for Personalized Medicine, Amsterdam UMC, Amsterdam, The Netherlands., Balážová M; Department of Membrane Biochemistry, Institute of Animal Biochemistry and Genetics, Centre of Biosciences, Slovak Academy of Sciences, 84005, Bratislava, Slovakia., Teixeira da Rosa N Jr; Department of Biological Sciences, Wayne State University, Detroit, MI, USA., Chakkour M; Department of Biological Sciences, Wayne State University, Detroit, MI, USA., Hazime S; Department of Biological Sciences, Wayne State University, Detroit, MI, USA., Ren M; Department of Anesthesiology, Perioperative Care, and Pain Medicine, Grossman School of Medicine, New York University, New York, NY, USA., Schlame M; Department of Anesthesiology, Perioperative Care, and Pain Medicine, Grossman School of Medicine, New York University, New York, NY, USA., Houtkooper RH; Laboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology and Metabolism Institute, Amsterdam, The Netherlands.; Amsterdam Cardiovascular Sciences Institute, Amsterdam, The Netherlands.; Emma Center for Personalized Medicine, Amsterdam UMC, Amsterdam, The Netherlands., Greenberg ML; Department of Biological Sciences, Wayne State University, Detroit, MI, USA. mgreenberg@wayne.edu.

المصدر: Scientific reports [Sci Rep] 2024 May 20; Vol. 14 (1), pp. 11497. Date of Electronic Publication: 2024 May 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Forkhead Box Protein O1*/metabolism , Forkhead Box Protein O1*/genetics , AMP-Activated Protein Kinases*/metabolism , Mice, Knockout* , Pyruvate Dehydrogenase Acetyl-Transferring Kinase*/metabolism , Pyruvate Dehydrogenase Acetyl-Transferring Kinase*/genetics, Animals ; Mice ; Transcription Factors/metabolism ; Transcription Factors/genetics ; Up-Regulation ; Signal Transduction ; Myoblasts/metabolism ; Cell Line ; Glucose/metabolism ; Acyltransferases

المؤلفون: Sedik AA; Pharmacology Department, Medical Research and Clinical Studies Institute, National Research Centre, El-Buhouth St., Dokki, Cairo, 12622, Egypt., Hussein DT; Fellow of Biochemistry, Children Hospital, Faculty of Medicine, Mansoura University, Mansoura, Egypt., Fathy K; Electron Microscopy Unit, Mansoura University, El Mansoura, 35516, Egypt., Mowaad NA; Narcotics, Ergogenics and Poisons Department, Medical Research and Clinical Studies Institute, National Research Centre, El-Buhouth St., Dokki, Cairo, 12622, Egypt. body27_9_80@yahoo.com.

المصدر: Scientific reports [Sci Rep] 2024 May 18; Vol. 14 (1), pp. 11396. Date of Electronic Publication: 2024 May 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Thioacetamide* , Sirtuin 1*/metabolism , Hepatic Encephalopathy*/drug therapy , Hepatic Encephalopathy*/metabolism , Hepatic Encephalopathy*/chemically induced , Neuroprotective Agents*/pharmacology , Neuroprotective Agents*/therapeutic use , Signal Transduction*/drug effects , AMP-Activated Protein Kinases*/metabolism, Animals ; Rats ; Male ; Oxidative Stress/drug effects ; Up-Regulation/drug effects ; Cognition/drug effects ; Brain/metabolism ; Brain/drug effects ; Brain/pathology ; Rats, Wistar ; Liver/drug effects ; Liver/metabolism ; Liver/pathology ; Disease Models, Animal

المؤلفون: Rahim HA; Department of Exercise Physiology, Faculty of Sport Sciences, University of Guilan, Rasht, Iran.; College of Physical Education and Sports Sciences, University of Halabja, Halabja, Iraq.; Cellular & Molecular Research Center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran., Damirchi A; Department of Exercise Physiology, Faculty of Sport Sciences, University of Guilan, Rasht, Iran., Babaei P; Neuroscience Research Center, Trauma Institute, Guilan University of Medical Sciences, Rasht, Iran. p_babaei@gums.ac.ir.; Cellular & Molecular Research Center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran. p_babaei@gums.ac.ir.; Department of Physiology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran. p_babaei@gums.ac.ir.

المصدر: Scientific reports [Sci Rep] 2024 May 17; Vol. 14 (1), pp. 11313. Date of Electronic Publication: 2024 May 17.

نوع المنشور: Journal Article; Comparative Study

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Fibrillin-1*/metabolism , Metabolic Syndrome*/metabolism , Metabolic Syndrome*/therapy , Signal Transduction* , Rats, Wistar* , Physical Conditioning, Animal* , Disease Models, Animal* , AMP-Activated Protein Kinases*/metabolism, Animals ; Rats ; Female ; High-Intensity Interval Training/methods ; Liver/metabolism ; Insulin Resistance ; Blood Glucose/metabolism ; Insulin/blood ; Insulin/metabolism ; Peptide Fragments/blood ; Peptide Fragments/metabolism

المؤلفون: Yang KJ; Clinical Research Institute, Daejeon St. Mary's Hospital, Daejeon, Republic of Korea., Park H; Division of Nephrology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Chang YK; Division of Nephrology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Park CW; Division of Nephrology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Kim SY; Division of Nephrology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Hong YA; Division of Nephrology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. amorfati00@gmail.com.

المصدر: Scientific reports [Sci Rep] 2024 May 15; Vol. 14 (1), pp. 11167. Date of Electronic Publication: 2024 May 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Glucose*/metabolism , Xanthine Dehydrogenase*/metabolism , Endothelial Cells*/metabolism , Endothelial Cells*/drug effects , AMP-Activated Protein Kinases*/metabolism, Humans ; Purines/pharmacology ; Signal Transduction/drug effects ; Febuxostat/pharmacology ; Kidney Glomerulus/metabolism ; Kidney Glomerulus/pathology ; Kidney Glomerulus/drug effects ; Oxidative Stress/drug effects ; Reactive Oxygen Species/metabolism

المؤلفون: Lin J; College of Physical Education, Yangzhou University, Yangzhou, 225009, China., Zhang X; College of Physical Education, Yangzhou University, Yangzhou, 225009, China., Sun Y; College of Physical Education, Yangzhou University, Yangzhou, 225009, China., Xu H; College of Physical Education, Yangzhou University, Yangzhou, 225009, China., Li N; College of Physical Education, Yangzhou University, Yangzhou, 225009, China., Wang Y; College of Physical Education, Yangzhou University, Yangzhou, 225009, China., Tian X; College of Physical Education, Yangzhou University, Yangzhou, 225009, China., Zhao C; College of Physical Education, Yangzhou University, Yangzhou, 225009, China., Wang B; College of Physical Education, Yangzhou University, Yangzhou, 225009, China., Zhu B; College of Physical Education, Yangzhou University, Yangzhou, 225009, China., Zhao R; College of Physical Education, Yangzhou University, Yangzhou, 225009, China. renqing.zhao@yzu.edu.cn.

المصدر: Scientific reports [Sci Rep] 2024 May 09; Vol. 14 (1), pp. 10658. Date of Electronic Publication: 2024 May 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: AMP-Activated Protein Kinases*/metabolism , Diabetes Mellitus, Experimental*/metabolism , Diabetes Mellitus, Experimental*/therapy , Fibronectins*/metabolism , Physical Conditioning, Animal*, Animals ; Male ; Rats ; Diabetes Mellitus, Type 2/metabolism ; Diabetes Mellitus, Type 2/therapy ; Inflammation/metabolism ; Insulin Resistance ; Mitochondrial Dynamics ; Muscle, Skeletal/metabolism ; Rats, Wistar ; Signal Transduction ; Streptozocin

المؤلفون: Minokoshi Y; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA., Kim YB; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA., Peroni OD; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA., Fryer LGD; The Cellular Stress Group, MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital, London, UK., Müller C; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA., Carling D; The Cellular Stress Group, MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital, London, UK., Kahn BB; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA. bkahn@caregroup.harvard.edu.

المصدر: Nature [Nature] 2024 May; Vol. 629 (8013), pp. E15.

نوع المنشور: Editorial; Expression of Concern

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: AMP-Activated Protein Kinases*/metabolism , Enzyme Activation*/drug effects , Fatty Acids*/metabolism , Leptin*/metabolism , Oxidation-Reduction*, Animals ; Humans ; Mice

المؤلفون: Fu TL; Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China., Li GR; Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China., Li DH; Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China., He RY; Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China., Liu BH; Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China.; Department of Thoracic Surgery, The First Hospital of Jilin University, Changchun, 130061, China., Xiong R; Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China., Xu CZ; Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China., Lu ZL; Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China., Song CK; Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China., Qiu HL; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, 430060, China., Wang WJ; Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China., Zou SS; Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China., Yi K; Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China., Li N; Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China. md.lining@whu.edu.cn., Geng Q; Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China. gengqingwhu@whu.edu.cn.

المصدر: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2024 May; Vol. 45 (5), pp. 1002-1018. Date of Electronic Publication: 2024 Jan 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE

مواضيع طبية MeSH: Xanthones*/pharmacology , Xanthones*/therapeutic use , Pulmonary Fibrosis*/drug therapy , Pulmonary Fibrosis*/metabolism , Sirtuin 3*/metabolism , Diabetes Mellitus, Experimental*/drug therapy , Diabetes Mellitus, Experimental*/complications , Diabetes Mellitus, Experimental*/metabolism , Forkhead Box Protein O3*/metabolism , AMP-Activated Protein Kinases*/metabolism , Mice, Inbred C57BL*, Animals ; Male ; Humans ; Mice ; Epithelial-Mesenchymal Transition/drug effects ; Human Umbilical Vein Endothelial Cells/drug effects ; Streptozocin ; Signal Transduction/drug effects ; Endothelial-Mesenchymal Transition

المؤلفون: Jia J; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; University of Science and Technology of China, Hefei, 230026, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China., Ji W; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; University of Science and Technology of China, Hefei, 230026, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China., Saliba AN; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, 55905, USA., Csizmar CM; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, 55905, USA.; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA., Ye K; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China., Hu L; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; University of Science and Technology of China, Hefei, 230026, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China., Peterson KL; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA., Schneider PA; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA., Meng XW; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA., Venkatachalam A; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA., Patnaik MM; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, 55905, USA., Webster JA; Adult Leukemia Program, Sidney Kimmel Cancer Center at Johns Hopkins, Baltimore, MD, 21287, USA., Smith BD; Adult Leukemia Program, Sidney Kimmel Cancer Center at Johns Hopkins, Baltimore, MD, 21287, USA., Ghiaur G; Adult Leukemia Program, Sidney Kimmel Cancer Center at Johns Hopkins, Baltimore, MD, 21287, USA., Wu X; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA., Zhong J; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA., Pandey A; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA.; Manipal Academy of Higher Education, Manipal, 576104, Kamataka, India., Flatten KS; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA., Deng Q; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China., Wang H; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China., Kaufmann SH; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, 55905, USA. Kaufmann.Scott@Mayo.edu.; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA. Kaufmann.Scott@Mayo.edu.; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA. Kaufmann.Scott@Mayo.edu., Dai H; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China. daih@cmpt.ac.cn.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China. daih@cmpt.ac.cn.; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA. daih@cmpt.ac.cn.

المصدر: Cell death and differentiation [Cell Death Differ] 2024 Apr; Vol. 31 (4), pp. 405-416. Date of Electronic Publication: 2024 Mar 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9437445 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5403 (Electronic) Linking ISSN: 13509047 NLM ISO Abbreviation: Cell Death Differ Subsets: MEDLINE

مواضيع طبية MeSH: Aniline Compounds*/pharmacology , Sulfonamides*/pharmacology , AMP-Activated Protein Kinases*/metabolism , bcl-X Protein*/metabolism , bcl-X Protein*/antagonists & inhibitors , Pyrimidines*/pharmacology , Myeloid Cell Leukemia Sequence 1 Protein*/metabolism , Myeloid Cell Leukemia Sequence 1 Protein*/antagonists & inhibitors, Humans ; Animals ; Mice ; Cell Line, Tumor ; Pyrazoles/pharmacology ; bcl-Associated Death Protein/metabolism ; Apoptosis/drug effects ; Cell Death/drug effects ; Leukemia/drug therapy ; Leukemia/pathology ; Leukemia/metabolism ; Phosphorylation/drug effects ; Peptide Fragments/pharmacology ; Proto-Oncogene Proteins/metabolism ; Proto-Oncogene Proteins/antagonists & inhibitors ; Drug Synergism