المؤلفون: Michael Privitera, Alok Dwivedi, Rachel S. Wasson, Susannah Cornes, Sian Cotton, Richard B. Lipton, Sheryl R. Haut, Jeffrey R. Strawn

المصدر: Neurology. 90:e963-e970

مصطلحات موضوعية: medicine.medical_specialty, business.industry, medicine.medical_treatment, Psychological intervention, Diaphragmatic breathing, medicine.disease, law.invention, Treatment and control groups, 03 medical and health sciences, Epilepsy, 0302 clinical medicine, Mood, Randomized controlled trial, law, medicine, Physical therapy, 030212 general & internal medicine, Neurology (clinical), Behavioral interventions, business, 030217 neurology & neurosurgery, Progressive muscle relaxation

الوصف: ObjectiveTo evaluate the effect of a stress-reduction intervention in participants with medication-resistant epilepsy.MethodsAdults with medication-resistant focal epilepsy (n = 66) were recruited from 3 centers and randomized to 1 of 2 interventions: (1) progressive muscle relaxation (PMR) with diaphragmatic breathing, or (2) control focused-attention activity with extremity movements. Following an 8-week baseline period, participants began 12 weeks of double-blind treatment. Daily self-reported mood and stress ratings plus seizure counts were completed by participants using an electronic diary, and no medication adjustments were permitted. The primary outcome was percent reduction in seizure frequency per 28 days comparing baseline and treatment; secondary outcomes included stress reduction and stress–seizure interaction.ResultsIn the 66 participants in the intention-to-treat analysis, seizure frequency was reduced from baseline in both treatment groups (PMR: 29%, p < 0.05; focused attention: 25%, p < 0.05). PMR and focused attention did not differ in seizure reduction (p = 0.38), although PMR was associated with stress reduction relative to focused attention (p < 0.05). Daily stress was not a predictor of seizures.ConclusionsBoth PMR and the focused-attention groups showed reduced seizure frequency compared to baseline in participants with medication-resistant focal seizures, although the 2 treatments did not differ. PMR was more effective than focused attention in reducing self-reported stress.ClinicalTrials.gov identifierNCT01444183.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::32d2aab74311ec09bd640744f2e8cf28
https://doi.org/10.1212/wnl.0000000000005109

المؤلفون: Michael S. Yi, Sian Cotton, Meghan E. McGrady, Janelle Hines, Yvonne Humenay Roberts, Susan L. Rosenthal, Joel Tsevat, Daniel H. Grossoehme

المصدر: Journal of Pediatric Hematology/Oncology. 31:313-318

مصطلحات موضوعية: Male, Religion and Psychology, Coping (psychology), Forgiveness, Adolescent, media_common.quotation_subject, Psychology, Adolescent, Pilot Projects, Anemia, Sickle Cell, Article, Religiosity, Young Adult, Adaptation, Psychological, Belief in God, Spirituality, Humans, Medicine, Young adult, Child, media_common, business.industry, Data Collection, Religion and Medicine, Attendance, Hematology, Prayer, Oncology, Chronic Disease, Pediatrics, Perinatology and Child Health, Female, business, Clinical psychology

الوصف: Religious/spiritual (R/S) coping has been associated with health outcomes in chronically ill adults; however, little is known about how adolescents use R/S to cope with a chronic illness such as sickle cell disease (SCD). Using a mixed method approach (quantitative surveys and qualitative interviews), we examined R/S coping, spirituality, and health-related quality of life in 48 adolescents with SCD and 42 parents of adolescents with SCD. Adolescents reported high rates of religious attendance and belief in God, prayed often, and had high levels of spirituality (e.g., finding meaning/peace in their lives and deriving comfort from faith). Thirty-five percent of adolescents reported praying once or more a day for symptom management. The most common positive R/S coping strategies used by adolescents were: “Asked forgiveness for my sins” (73% of surveys) and “Sought God’s love and care” (73% of surveys). Most parents used R/S coping strategies to cope with their child’s illness. R/S coping was not significantly associated with HRQOL (p = NS). R/S coping, particularly prayer, was relevant for adolescents with SCD and their parents. Future studies should assess adolescents’ preferences for discussing R/S in the medical setting and whether R/S coping is related to HRQOL in larger samples.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2c0e49739ac09569478cb3c20e018be
https://doi.org/10.1097/mph.0b013e31819e40e3