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1
المؤلفون: Lingyun Sun, Jun J. Mao, Hyeongjun Yun
المصدر: JNCI Monographs. 2017
مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Music therapy, media_common.quotation_subject, MEDLINE, Web Browser, Medical Oncology, Bioinformatics, 03 medical and health sciences, 0302 clinical medicine, Health care, medicine, Acupuncture, Humans, 030212 general & internal medicine, Meditation, media_common, Integrative Medicine, Massage, business.industry, Cancer Care Facilities, Articles, General Medicine, National Cancer Institute (U.S.), United States, Oncology, 030220 oncology & carcinogenesis, Family medicine, Comprehensive Health Care, Integrative medicine, business
الوصف: Background Cancer centers have increasingly offered integrative medicine therapies in response to their patients' unmet needs. We evaluated the growth of integrative medicine in leading academic cancer centers in the United States as reflected by their public-facing websites. Methods We performed a systematic review of 45 National Cancer Institute (NCI)-designated comprehensive cancer center websites. Two researchers independently evaluated whether the websites provided information regarding integrative medicine modalities and, if so, whether the services were provided in the same health system. They compared the proportion of cancer centers providing the information on each modality in 2016 with the data from the prior study in 2009. Results The most common integrative medicine therapies mentioned on the 45 NCI-designated comprehensive cancer center websites were exercise (97.8%) and acupuncture and meditation (88.9% each), followed by yoga (86.7%), massage (84.4%), and music therapy (82.2%). The majority of the websites also provided information on nutrition (95.6%), dietary supplements (93.3%), and herbs (88.9%). The most common therapies offered in the health systems were acupuncture/massage (73.3% each), meditation/yoga (68.9% each), and consultations about nutrition (91.1%), dietary supplements (84.4%), and herbs (66.7%). Compared with 2009, there was a statistically significant increase in the number of websites mentioning acupuncture, dance therapy, healing touch, hypnosis, massage, meditation, Qigong, and yoga (all P Conclusions Leading US cancer centers increasingly present integrative medicine content on their websites, and the majority of them provide these services to patients in the same health systems.
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ca3bc0df4219e805187a1d637f7ade
https://doi.org/10.1093/jncimonographs/lgx004 -
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المؤلفون: T. Conrad Gilliam, Natalia Maltsev, Gady Agam, Sheng Wang, Somaye Hashemifar, Mark D'Souza, Andrew Taylor, Bingqing Xie, Utpal J. Dave, Jinbo Xu, Steven R. White, Dinanath Sulakhe, Sandhya Balasubramanian
المصدر: Nucleic Acids Research
مصطلحات موضوعية: 0301 basic medicine, computer.internet_protocol, Knowledge Bases, Biology, Bioinformatics, computer.software_genre, 03 medical and health sciences, Annotation, Knowledge extraction, Databases, Genetic, Genetics, Data Mining, Humans, Database Issue, Gene Regulatory Networks, Integrative Medicine, Information retrieval, business.industry, Molecular Sequence Annotation, Service-oriented architecture, 3. Good health, Phenotype, 030104 developmental biology, Genes, Knowledge base, Workbench, The Internet, Web service, business, computer
الوصف: Lynx (http://lynx.ci.uchicago.edu) is a web-based database and a knowledge extraction engine. It supports annotation and analysis of high-throughput experimental data and generation of weighted hypotheses regarding genes and molecular mechanisms contributing to human phenotypes or conditions of interest. Since the last release, the Lynx knowledge base (LynxKB) has been periodically updated with the latest versions of the existing databases and supplemented with additional information from public databases. These additions have enriched the data annotations provided by Lynx and improved the performance of Lynx analytical tools. Moreover, the Lynx analytical workbench has been supplemented with new tools for reconstruction of co-expression networks and feature-and-network-based prioritization of genetic factors and molecular mechanisms. These developments facilitate the extraction of meaningful knowledge from experimental data and LynxKB. The Service Oriented Architecture provides public access to LynxKB and its analytical tools via user-friendly web services and interfaces.
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6a7a85f8407b9c39c1349eab3c9ca68
https://doi.org/10.1093/nar/gkv1257 -
3
المؤلفون: Roxana, Delgado, Alexandra, York, Courtney, Lee, Cindy, Crawford, Chester, Buckenmaier, Eric, Schoomaker, Paul, Crawford
المصدر: Pain Medicine. 15:S9-S20
مصطلحات موضوعية: Complementary Therapies, medicine.medical_specialty, Evidence-based practice, Pain medicine, law.invention, Physical medicine and rehabilitation, Randomized controlled trial, law, medicine, Humans, Pain Management, Intensive care medicine, Integrative Medicine, Evidence-Based Medicine, Modalities, Self-management, business.industry, Chronic pain, General Medicine, medicine.disease, Self Care, Anesthesiology and Pain Medicine, Systematic review, Neurology (clinical), Integrative medicine, Chronic Pain, business
الوصف: Objectives Chronic pain management typically consists of prescription medications or provider-based, behavioral, or interventional procedures that are often ineffective, may be costly, and can be associated with undesirable side effects. Because chronic pain affects the whole person (body, mind, and spirit), patient-centered complementary and integrative medicine (CIM) therapies that acknowledge the patients' roles in their own healing processes have the potential to provide more efficient and comprehensive chronic pain management. Active self-care CIM (ACT-CIM) therapies allow for a more diverse, patient-centered treatment of complex symptoms, promote self-management, and are relatively safe and cost-effective. To date, there are no systematic reviews examining the full range of ACT-CIM used for chronic pain symptom management. Methods A systematic review was conducted, using Samueli Institute's Rapid Evidence Assessment of the Literature methodology, to rigorously assess both the quality of the research on ACT-CIM modalities and the evidence for their efficacy and effectiveness in treating chronic pain symptoms. A working group of subject matter experts was also convened to evaluate the overall literature pool and develop recommendations for the use and implementation of these modalities. Results Following key database searches, 146 randomized controlled trials were included in the review. Conclusions This article provides an introduction and background to the review, summarizes the methodological processes involved, details the initial results, and identifies strengths and weakness of the review. Specific results of the review as well as overall recommendations for moving this field of research forward are detailed throughout the current Pain Medicine supplement.
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المؤلفون: Courtney Lee, Christopher Spevak, Cindy Crawford, Lynn Teo
المصدر: Pain Medicine. 15:S96-S103
مصطلحات موضوعية: medicine.medical_specialty, Modality (human–computer interaction), Modalities, business.industry, Pain medicine, Chronic pain, Alternative medicine, General Medicine, medicine.disease, law.invention, Anesthesiology and Pain Medicine, Systematic review, Randomized controlled trial, law, Physical therapy, medicine, Neurology (clinical), Integrative medicine, business
الوصف: Objectives Chronic pain management typically consists of prescription medications or provider-based, behavioral, or interventional procedures that are often ineffective, may be costly, and can be associated with undesirable side effects. Because chronic pain affects the whole person (body, mind, and spirit), patient-centered complementary and integrative medicine (CIM) therapies that acknowledge the patients' roles in their own healing processes have the potential to provide more efficient and comprehensive chronic pain management. Active self-care CIM therapies (ACT-CIM) allow for a more diverse, patient-centered treatment of complex symptoms, promote self-management, and are relatively safe and cost-effective. To date, there are no systematic reviews examining the full range of ACT-CIM used for chronic pain symptom management. Methods A systematic review was conducted, using Samueli Institute's rapid evidence assessment of the literature (REAL©) methodology, to rigorously assess both the quality of the research on ACT-CIM modalities and the evidence for their efficacy and effectiveness in treating chronic pain symptoms. A working group of subject matter experts was also convened to evaluate the overall literature pool and develop recommendations for the use and implementation of these modalities. Results Following key database searches, 146 randomized controlled trials, covering 33 different pain conditions, were included in the review. Conclusions This article categorized studies by pain condition, describing the diagnostic criteria used and modalities that seem most effective for each condition. Complexities associated with investigating chronic pain populations are also discussed. The entire scope of the review, categorized by modality rather than pain condition, is detailed throughout the current Pain Medicine supplement.
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المؤلفون: Andrew Taylor, Eduardo Berrocal, T. Conrad Gilliam, Sandhya Balasubramanian, Dinanath Sulakhe, Bingqing Xie, Jinbo Xu, Natalia Maltsev, Utpal J. Dave, Daniela Börnigen, Sheng Wang, Bo Feng
المصدر: Nucleic Acids Research
مصطلحات موضوعية: Knowledge Bases, Biology, computer.software_genre, 03 medical and health sciences, Annotation, 0302 clinical medicine, Knowledge extraction, Seizures, Databases, Genetic, Genetics, Humans, Disease, Autistic Disorder, 030304 developmental biology, Internet, 0303 health sciences, Database, business.industry, Experimental data, Genomics, 3. Good health, Variety (cybernetics), Search Engine, Systems Integration, VI. Genomic variation, diseases and drugs, Phenotype, Genes, Knowledge base, The Internet, Integrative medicine, Web service, business, computer, 030217 neurology & neurosurgery
الوصف: We have developed Lynx (http://lynx.ci.uchicago.edu)—a web-based database and a knowledge extraction engine, supporting annotation and analysis of experimental data and generation of weighted hypotheses on molecular mechanisms contributing to human phenotypes and disorders of interest. Its underlying knowledge base (LynxKB) integrates various classes of information from >35 public databases and private collections, as well as manually curated data from our group and collaborators. Lynx provides advanced search capabilities and a variety of algorithms for enrichment analysis and network-based gene prioritization to assist the user in extracting meaningful knowledge from LynxKB and experimental data, whereas its service-oriented architecture provides public access to LynxKB and its analytical tools via user-friendly web services and interfaces.
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5af15753a1de72d691fb50f9d1d885
https://doi.org/10.1093/nar/gkt1166 -
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المؤلفون: Frances McSherry, Patrick Healy, Henry S. Friedman, Dina Randazzo, Eric S. Lipp, James E. Herndon, Annick Desjardins, Mary Lou Affronti, Katherine B. Peters
المصدر: Neuro-Oncology. 19:vi202-vi202
مصطلحات موضوعية: Gerontology, Cancer Research, medicine.medical_specialty, animal structures, Standard of care, business.industry, Alternative medicine, medicine.disease, Abstracts, 03 medical and health sciences, 0302 clinical medicine, Oncology, 030220 oncology & carcinogenesis, Survivorship curve, Medicine, Neurology (clinical), Integrative medicine, Single institution, business, 030217 neurology & neurosurgery, Glioblastoma
الوصف: Complementary and Alternative Medicine (CAM) uses diverse practices and products that are not a part of standard of care while Integrative Medicine combines both CAM and conventional medicine. Given the poor prognosis of glioblastoma (GBM), many patients will explore other options to improve survival or quality of life. We sought to examine the association between CAM modalities and survivorship. In this cross-sectional retrospective analysis, data about CAM treatment and self-help practices were obtained from the modified International Complementary and Alternative Medicine Questionnaire (I-CAM-Q). CAM treatment included modalities such as vitamins/supplements, massage, energy work, or acupuncture, while CAM self-help practices consisted of praying, exercise, visualization, meditation, relaxation, or diet. Survival was defined by date of questionnaire completion to date of death. There were 365 GBM patients (31% censored) with a median overall survival (mOS) of 14.1months, 95% CI: 12.2, 17.0. Those patients who used CAM self-help practices (n=188, mOS =16.2 months, 95% CI: 12.2, 18.1) and CAM treatments (n=237, mOS = 15.5 months, 95% CI: 9.9, 18.1) did not have any association with survival compared to those who did not use self-help (n=65; mOS = 20.9 months, 95% CI: 12.7, 39.1) or CAM treatments (n=74, mOS = 15.5 months, 95% CI: 9.9, 18.1). The most popular modalities used, prayer (n=171, 15.1 vs 22.7 months) and supplements (n=220; 14.7 vs 16.5 months) were also not associated with survival. The use of CAM was not a predictor of survival whereas those who were multifocal, grade IV, older than 55, or had recurrent disease had significantly poorer survival. It is difficult to accurately predict survival benefit because of this study’s cross-sectional design. Due to the increased interest in CAM in the primary brain tumor population, a prospective analysis utilizing some of these self- help practices or treatments may be warranted.
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::491d831bf3aeaa459c45e6271bee99c4
https://doi.org/10.1093/neuonc/nox168.816 -
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المؤلفون: Margaret A. Chesney, Benjamin Kligler
المصدر: JNCI Monographs. 2014:292-293
مصطلحات موضوعية: Academic Medical Centers, Integrative Medicine, Cancer Research, Medical education, Integrative Oncology, business.industry, MEDLINE, Holistic Health, General Medicine, Holistic health, Mind–body interventions, Quality of life (healthcare), Oncology, Neoplasms, Behavioral medicine, Health care, Humans, Medicine, Societies, Hospital, Survivors, Integrative medicine, business
الوصف: As evidenced by this issue of JNCI Monographs, integrative medicine is rapidly gaining ground as part of the practice of oncology in the United States. The Consortium of Academic Health Centers for Integrative Medicine—an organization comprised of 57 academic health centers and health systems in North America—defines inte grative medicine as follows: Integrative Medicine is the practice of medicine that reaffirms the importance of the relationship between practitioner and patient, focuses on the whole person, is informed by evidence, and makes use of all appropriate therapeutic approaches, healthcare professionals and disciplines to achieve optimal health and healing. As this definition implies, although an openness to using therapies such as acupuncture or massage is a component of the integrative approach, integrative medicine goes far beyond simply combining the therapies previously described as “complementary/alternative medicine” with conventional care. It describes a change in philosophy, which expands our role beyond that of treating disease to reaffirm the commitment to treating the whole person. Almost more than anywhere else in medicine, the practice of oncology and the work of caring for a patient with cancer and their family clearly call for this approach and for a commitment to whole-person care. Lifestyle counseling, behavioral medicine interventions, and spiritual support all play critical roles in this integrative approach, alongside the use of other therapeutic strategies rooted in a rigorous evidence-based approach to the best conventional care. This is integrative medicine for cancer. The mission of the Consortium of Academic Health Centers for Integrative Medicine (the Consortium) is to advance the principles and practices of integrative health care within academic institutions. Having grown significantly since its founding in 2002 with only 13 member institutions, the Consortium’s mission is accomplished through supporting and mentoring academic leaders, faculty, and students to advance integrative health-care curricula, research, and clinical care; disseminating information on rigorous scientific research, educational curricula in integrative health, and sustainable models of clinical care; and working to inform health-care policy. This issue is a perfect example of how the Consortium’s support for collaboration between researchers and institutions is critical in the emergence of this new field and in the effort to make healthcare practitioners aware of its potential for our patients. The idea emerged from our Research Working Group, chaired at the time by Dr Jun Mao, coeditor of this supplement. Dr Mao felt strongly that we had reached a critical mass of high-quality research on the role of integrative medicine in cancer survivorship and that there was a pressing need to provide an outlet to make this new knowledge available to the larger worlds of oncology and medicine. With support from his colleagues on the Research Working Group and with funding from their six member institutions, the Consortium at large, and the Society for Integrative Oncology, Dr Mao and Dr Cohen were successful in making this idea a reality. None of this would have been possible without the environment of supportive collaboration, which is the foundation of our organization. As we know, living through the treatment of a cancer and surviving in its aftermath pose daunting challenges for many of our patients. The recent advances in the treatment of many cancers notwithstanding, the impact on patients’ quality of life of both the treatment process and the fear of recurrence is staggering. This is an area where integrative medicine can play a very important role in cancer care. In this issue, authors present their findings on a wide variety of integrative approaches to different dimensions of this survivor experience, including the potential impact of mind–body therapies such as meditation and tai chi in addressing the common problems of insomnia and anxiety; the role of diet change and exercise in survivorship; and the impact of patients’ expectations and preferences on the effectiveness of integrative approaches to managing symptoms. The articles also demonstrate the wide range of patient populations and clinical settings in which integrative
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09a16db3df1f745a2793f4978958e0c1
https://doi.org/10.1093/jncimonographs/lgu039 -
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المؤلفون: Jeffery A. Dusek, Jun J. Mao
المصدر: Pain Medicine. :pnw102
مصطلحات موضوعية: medicine.medical_specialty, business.industry, Chronic pain, MEDLINE, Alternative medicine, General Medicine, Pain management, medicine.disease, INTEGRATVIVE MEDICINE SECTION, Mind–body interventions, 03 medical and health sciences, 0302 clinical medicine, Anesthesiology and Pain Medicine, 030220 oncology & carcinogenesis, Family medicine, Health care, medicine, National Health Interview Survey, 030212 general & internal medicine, Neurology (clinical), Integrative medicine, business
الوصف: According to a recent study using data from the 2012 National Health Interview Survey, chronic or severe pain affects roughly 30% of U.S. adults and is one of the most common reasons for seeking medical care [1,2]. Considering health care expenses and lost productivity, chronic pain is estimated to cost the U.S. $100 billion annually [3]. While medications and surgical techniques are important tools in the management of pain, many individuals may not have adequate pain relief from these approaches alone. In recent years, the epidemic of opioid abuse and overuse has made management of pain particularly challenging for clinicians and patients [4]. Thus, many individuals with pain seek complementary and alternative medicine [1,5,6]. The field of complementary and alternative medicine, originally defined as therapies and practices not taught in U.S. medical schools or available to U.S. hospitals, is evolving into the field of integrative medicine [7] or complementary …
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المؤلفون: Chester C. Buckenmaier, Eric Schoomaker
المصدر: Pain Medicine. 15:S7-S8
مصطلحات موضوعية: medicine.medical_specialty, business.industry, Public health, Alternative medicine, Chronic pain, General Medicine, medicine.disease, Military medicine, Anesthesiology and Pain Medicine, Blueprint, Health care, Medicine, Neurology (clinical), Integrative medicine, Medical prescription, business, Psychiatry
الوصف: In 2011, the Institute of Medicine (IOM) report Relieving Pain in America: A Blueprint for Transforming Prevention, Care, Education, and Research publicized the ongoing public health crisis of chronic pain, which was costing American society at least $560–$635 billion annually. This figure represents the monetary impact of providing health care to pain patients and the cost of this health issue in lost productivity. It does not account for the incalculable toll in human suffering underlying these extraordinary figures. Perhaps the most significant outcome of this landmark report was the call by the authors for a “cultural transformation in the way clinicians and the public view pain and its treatment” [1]. Preceding the IOM report was the military's own Pain Management Task Force Final Report (May 2010) [2], which was created during what has become the longest military conflict in American history. The PMTF noted that military medicine met and often exceeded civilian standards of pain care but was experiencing many of the same challenges as civilian medicine in dealing with chronic pain conditions, particularly an overreliance on over-the-counter and prescription pain medications. Perhaps a fundamental difference between these two landmark documents was the heightened sense of urgency expressed in the PMTF report as the country was entering its ninth year of war and the challenges of pain management in war wounded were becoming ever more apparent. The military medical response to the recent conflict has been a historic success, …
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المؤلفون: Jeffery A Dusek, Natalie L Dyer, Jessica Surdam
المصدر: Pain Med
مصطلحات موضوعية: Complementary Therapies, medicine.medical_specialty, medicine.medical_treatment, Psychological intervention, 03 medical and health sciences, 0302 clinical medicine, Anthroposophic medicine, Health care, medicine, Acupuncture, Humans, Pain Management, Outpatient clinic, 030212 general & internal medicine, Integrative Medicine Section, business.industry, General Medicine, Chiropractic, Call to action, Anesthesiology and Pain Medicine, Family medicine, Neurology (clinical), Integrative medicine, business, Delivery of Health Care, 030217 neurology & neurosurgery
الوصف: Objective The goal of this systematic review was to evaluate practice-based, real-world research of individualized complementary and integrative health (CIH) therapies for pain as provided in CIH outpatient clinics. Methods A systematic review was conducted on articles in PubMed, Ovid, Cochrane, Web of Science, Scopus, and Embase published through December 2020. The study was listed in the PROSPERO database (CRD42020159193). Major categories of variables extracted included study details and demographics, interventions, and outcomes. Results The literature search yielded 3,316 records, with 264 assessed for full-text review. Of those, 23 studies (including ∼8,464 patients) were specific to pain conditions as a main outcome. Studies included chiropractic, acupuncture, multimodal individualized intervention/programs, physiotherapy, and anthroposophic medicine therapy. Retention rates ranged from 53% to 91%, with studies offering monetary incentives showing the highest retention. The 0–10 numerical rating scale was the most common pain questionnaire (n = 10; 43% of studies), with an average percent improvement across all studies and time points of 32% (range: 18–60%). Conclusions Findings from this systematic review of practice-based, real-word research indicate that CIH therapies exert positive effects on various pain outcomes. Although all studies reported beneficial impacts on one or more pain outcomes, the heterogeneous nature of the studies limits our overall understanding of CIH as provided in clinical settings. Accordingly, we present numerous recommendations to improve publication reporting and guide future research. Our call to action is that future practice-based CIH research is needed, but it should be more expansive and conducted in association with a CIH scientific society with academic and health care members.
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