المؤلفون: Lewis A; Centre for Genomics and Child Health, Blizard Institute, Barts and The London School of Medicine & Dentistry, London E1 2AT, U.K., Sánchez S; Cancer Heterogeneity Lab, CIC bioGUNE, 48160 Derio, Spain., Berti G; Centre for Genomics and Child Health, Blizard Institute, Barts and The London School of Medicine & Dentistry, London E1 2AT, U.K., Pan-Castillo B; Centre for Genomics and Child Health, Blizard Institute, Barts and The London School of Medicine & Dentistry, London E1 2AT, U.K., Nijhuis A; Centre for Genomics and Child Health, Blizard Institute, Barts and The London School of Medicine & Dentistry, London E1 2AT, U.K., Mehta S; Centre for Genomics and Child Health, Blizard Institute, Barts and The London School of Medicine & Dentistry, London E1 2AT, U.K., Eleid L; Centre for Genomics and Child Health, Blizard Institute, Barts and The London School of Medicine & Dentistry, London E1 2AT, U.K., Gordon H; Centre for Immunobiology, Blizard Institute, Barts and The London School of Medicine & Dentistry, London E1 2AT, U.K., Gadhok R; Centre for Immunobiology, Blizard Institute, Barts and The London School of Medicine & Dentistry, London E1 2AT, U.K., Kimberley C; Centre for Genomics and Child Health, Blizard Institute, Barts and The London School of Medicine & Dentistry, London E1 2AT, U.K., Minicozzi A; Department of Colorectal Surgery, Division of Surgery & Perioperative Care, The Royal London Hospital, Whitechapel, London E1 1BB, U.K., Chin-Aleong J; Department of Histopathology, The Royal London Hospital, London E1 1BB, U.K., Feakins R; Department of Cellular Pathology, Royal Free London NHS Foundation Trust, London NW3 2QG, U.K., Kypta R; Cancer Heterogeneity Lab, CIC bioGUNE, 48160 Derio, Spain.; Department of Surgery and Cancer, Imperial College London, London W12 0NN, U.K., Lindsay JO; Centre for Immunobiology, Blizard Institute, Barts and The London School of Medicine & Dentistry, London E1 2AT, U.K., Silver A; Centre for Genomics and Child Health, Blizard Institute, Barts and The London School of Medicine & Dentistry, London E1 2AT, U.K.

المصدر: Clinical science (London, England : 1979) [Clin Sci (Lond)] 2022 Oct 14; Vol. 136 (19), pp. 1405-1423.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Portland Press on behalf of the Medical Research Society and the Biochemical Society Country of Publication: England NLM ID: 7905731 Publication Model: Print Cited Medium: Internet ISSN: 1470-8736 (Electronic) Linking ISSN: 01435221 NLM ISO Abbreviation: Clin Sci (Lond) Subsets: MEDLINE

مواضيع طبية MeSH: Crohn Disease*/drug therapy , Crohn Disease*/metabolism , Crohn Disease*/pathology , beta Catenin*/metabolism, Collagen Type I/metabolism ; Fibrosis ; Formaldehyde/metabolism ; Humans ; Intestines ; Ligands ; Myofibroblasts/metabolism ; RNA, Small Interfering/metabolism ; Transforming Growth Factor beta1/metabolism ; Wnt Signaling Pathway

المؤلفون: Nijhuis A; Centre for Digestive Diseases and National Centre for Bowel Research and Surgical Innovation, Blizard Institute, Barts and The London School of Medicine and Dentistry, London, U.K., Biancheri P; †Centre for Immunology and Infectious Disease, Blizard Institute, Barts and The London School of Medicine and Dentistry, London, U.K., Lewis A; Centre for Digestive Diseases and National Centre for Bowel Research and Surgical Innovation, Blizard Institute, Barts and The London School of Medicine and Dentistry, London, U.K., Bishop CL; ‡Centre for Cutaneous Research, Blizard Institute, Barts and The London School of Medicine and Dentistry, London, U.K., Giuffrida P; †Centre for Immunology and Infectious Disease, Blizard Institute, Barts and The London School of Medicine and Dentistry, London, U.K., Chan C; §Academic Surgery Unit, Royal London Hospital, London, U.K., Feakins R; ¶Department of Cellular Pathology, Royal London Hospital, London, U.K., Poulsom R; Centre for Digestive Diseases and National Centre for Bowel Research and Surgical Innovation, Blizard Institute, Barts and The London School of Medicine and Dentistry, London, U.K., Di Sabatino A; ∥Department of Internal Medicine, S. Matteo Hospital, University of Pavia, Pavia, Italy., Corazza GR; ∥Department of Internal Medicine, S. Matteo Hospital, University of Pavia, Pavia, Italy., MacDonald TT; †Centre for Immunology and Infectious Disease, Blizard Institute, Barts and The London School of Medicine and Dentistry, London, U.K., Lindsay JO; Centre for Digestive Diseases and National Centre for Bowel Research and Surgical Innovation, Blizard Institute, Barts and The London School of Medicine and Dentistry, London, U.K., Silver AR; Centre for Digestive Diseases and National Centre for Bowel Research and Surgical Innovation, Blizard Institute, Barts and The London School of Medicine and Dentistry, London, U.K.

المصدر: Clinical science (London, England : 1979) [Clin Sci (Lond)] 2014 Sep; Vol. 127 (5), pp. 341-50.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Portland Press on behalf of the Medical Research Society and the Biochemical Society Country of Publication: England NLM ID: 7905731 Publication Model: Print Cited Medium: Internet ISSN: 1470-8736 (Electronic) Linking ISSN: 01435221 NLM ISO Abbreviation: Clin Sci (Lond) Subsets: MEDLINE

مواضيع طبية MeSH: Collagen Type I/*biosynthesis , Collagen Type III/*biosynthesis , Crohn Disease/*pathology , MicroRNAs/*biosynthesis, Adolescent ; Adult ; Aged ; Collagen Type I/genetics ; Collagen Type III/genetics ; Constriction, Pathologic/metabolism ; Crohn Disease/genetics ; Down-Regulation ; Fibrosis ; Humans ; Intestinal Mucosa/metabolism ; MicroRNAs/metabolism ; Middle Aged ; Transforming Growth Factor beta1/pharmacology ; Up-Regulation