المؤلفون: Yingxue Ren, Yan W. Asmann, Tomonori Aikawa, Takahisa Kanekiyo, Guojun Bu, Takaomi C. Saido, Marie Louise Holm, Yu Yamazaki, Casey T. Anderson, Michael L. Fitzgerald, Takashi Saito, Masaya Tachibana, Yuka A. Martens, Madeleine R. Johnson

المصدر: Proc Natl Acad Sci U S A

مصطلحات موضوعية: Lipopolysaccharide, Mice, Transgenic, Inflammation, Haploinsufficiency, ABCA7, Proinflammatory cytokine, Pathogenesis, Mice, chemistry.chemical_compound, Immune system, Alzheimer Disease, medicine, Animals, Amyloid beta-Peptides, Multidisciplinary, Microglia, biology, business.industry, Gene Expression Profiling, Brain, Biological Sciences, Immunity, Innate, medicine.anatomical_structure, chemistry, Knockout mouse, Immunology, biology.protein, ATP-Binding Cassette Transporters, medicine.symptom, Transcriptome, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc9f2cc6a7da4030f630a177339a19c3
https://doi.org/10.1073/pnas.1908529116

المؤلفون: Satoshi Yamashita, Takeshi Ikeuchi, Tadafumi Hashimoto, Airi Tarutani, Shigeo Murayama, Masato Hasegawa, Kenichi Nagata, Toshikazu Ushijima, Taro Bannai, Takaomi C. Saido, Ryo Yamasaki, Junko Takahashi-Fujigasaki, Takeshi Iwatsubo, Kagari Koshi-Mano, Takashi Nonaka, Tatsuo Mano, Shoji Tsuji, Atsushi Iwata, Yasumasa Ohyagi, Akira Tamaoka, Ryo Ohtomo, Takeyuki Tsuchida, Tomohiro Imamura

المصدر: Proceedings of the National Academy of Sciences of the United States of America

مصطلحات موضوعية: 0301 basic medicine, Medical Sciences, DNA repair, DNA damage, tau Proteins, methylome, Biology, Bioinformatics, Epigenesis, Genetic, Pathogenesis, Amyloid beta-Protein Precursor, 03 medical and health sciences, Alzheimer Disease, medicine, Animals, Humans, Epigenetics, Promoter Regions, Genetic, Neurons, Amyloid beta-Peptides, Neuronal Plasticity, Multidisciplinary, BRCA1 Protein, Brain, DNA Methylation, Biological Sciences, BRCA1, Up-Regulation, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, PNAS Plus, Synaptic plasticity, DNA methylation, DNA fragmentation, Neuron, Alzheimer’s disease, Neuroscience, DNA Damage, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856d0a6d5cb2791f3e1b2cc630fecad8
https://doi.org/10.1073/pnas.1707151114

المؤلفون: Yuriko Tachida, Ritsuko Oka, Shinobu Kitazume, Takaomi C. Saido, Keiro Shirotani, Yasuhiro Hashimoto

المصدر: Proceedings of the National Academy of Sciences. 98:13554-13559

مصطلحات موضوعية: Sialyltransferase, Molecular Sequence Data, Golgi Apparatus, Cleavage (embryo), Cell Line, Substrate Specificity, Amyloid beta-Protein Precursor, symbols.namesake, Alzheimer Disease, Chlorocebus aethiops, Endopeptidases, mental disorders, Amyloid precursor protein, Animals, Aspartic Acid Endopeptidases, Humans, Secretion, Amino Acid Sequence, beta-D-Galactoside alpha 2-6-Sialyltransferase, Multidisciplinary, COS cells, biology, Biological Sciences, Golgi apparatus, Fusion protein, Molecular biology, Sialyltransferases, Mutagenesis, COS Cells, biology.protein, symbols, Amyloid Precursor Protein Secretases, Amyloid precursor protein secretase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa6a4142e1b984ef2314e9e87d581da
https://doi.org/10.1073/pnas.241509198

المؤلفون: Naren L. Banik, Kurt E. Schaecher, Donald C. Shields, Takaomi C. Saido

المصدر: Proceedings of the National Academy of Sciences. 96:11486-11491

مصطلحات موضوعية: Multiple Sclerosis, Transcription, Genetic, Fluorescent Antibody Technique, Protein degradation, White matter, Myelin, Western blot, medicine, Humans, Calpastatin, Multidisciplinary, biology, medicine.diagnostic_test, Calpain, Multiple sclerosis, Calcium-Binding Proteins, Proteolytic enzymes, Biological Sciences, medicine.disease, Molecular biology, medicine.anatomical_structure, Protein Biosynthesis, biology.protein, Calcium, Demyelinating Diseases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b3810d5734670c76ac64d226da972a1
https://doi.org/10.1073/pnas.96.20.11486