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المؤلفون: Hirotsugu Yanai, Tomoharu Sugie, Katsuhiro Yoshikawa, Koji Tsuta, Mitsugu Sekimoto, Mitsuaki Ishida
المصدر: PLoS ONE
PLoS ONE, Vol 16, Iss 2, p e0245725 (2021)مصطلحات موضوعية: 0301 basic medicine, Oncology, Colorectal cancer, Adjuvant Chemotherapy, H&E stain, Cancer Treatment, Triple Negative Breast Neoplasms, Kaplan-Meier Estimate, Single Center, Hospitals, University, 0302 clinical medicine, Breast Tumors, Medicine and Health Sciences, Prospective cohort study, skin and connective tissue diseases, Triple-negative breast cancer, Aged, 80 and over, Multidisciplinary, Pharmaceutics, Middle Aged, Prognosis, 030220 oncology & carcinogenesis, Medicine, Female, Anatomy, Research Article, Clinical Oncology, Adult, medicine.medical_specialty, Histology, Science, Surgical and Invasive Medical Procedures, Disease-Free Survival, Lymphatic System, 03 medical and health sciences, Cancer Chemotherapy, Breast cancer, Lymphocytes, Tumor-Infiltrating, Drug Therapy, Diagnostic Medicine, Internal medicine, Breast Cancer, medicine, Carcinoma, Chemotherapy, Humans, Pathological, Aged, Retrospective Studies, Colorectal Cancer, business.industry, Cancers and Neoplasms, Biology and Life Sciences, medicine.disease, 030104 developmental biology, sense organs, Lymph Nodes, Clinical Medicine, Neoplasm Recurrence, Local, business
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المؤلفون: Michael L. Bittner, Rosana Lopes, Jianping Hua, Chao Sima, Aniruddha Datta, Haswanth Vundavilli
المصدر: PLoS ONE
PLoS ONE, Vol 16, Iss 2, p e0247190 (2021)مصطلحات موضوعية: 0301 basic medicine, Colorectal cancer, Carcinogenesis, Cancer Treatment, Gene Expression, Apoptosis, medicine.disease_cause, Biochemistry, Suppressor Genes, 0302 clinical medicine, Medicine and Health Sciences, Medicine, Multidisciplinary, Cell Death, Pharmaceutics, Gene Expression Regulation, Neoplastic, Crosstalk (biology), Oncology, Cell Processes, 030220 oncology & carcinogenesis, Colorectal Neoplasms, HT29 Cells, Research Article, Signal Transduction, Programmed cell death, medicine.medical_specialty, Science, Tumor Suppressor Genes, 03 medical and health sciences, Drug Therapy, Gene Types, Molecular genetics, DNA-binding proteins, Genetics, Humans, Gene Regulation, Transcription factor, Cell Proliferation, Colorectal Cancer, business.industry, Cancer, Cancers and Neoplasms, Biology and Life Sciences, Proteins, Cell Biology, Phenanthrenes, medicine.disease, HCT116 Cells, digestive system diseases, Regulatory Proteins, 030104 developmental biology, Mutation, Cancer research, business, Transcription Factors
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المؤلفون: Laurence Calzone, Lorenzo Pantolini, Vincent Noël, Jonas Béal, Emmanuel Barillot
المصدر: PLoS Computational Biology
PLoS Computational Biology, Vol 17, Iss 1, p e1007900 (2021)مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Patient-Specific Modeling, Cell signaling, Skin Neoplasms, Colorectal cancer, Computer science, Cell, Cancer Treatment, Signal transduction, Synthetic Genome Editing, Genome Engineering, Omics data, Machine Learning, 0302 clinical medicine, Medicine and Health Sciences, CRISPR, Logical data model, Biology (General), Melanoma, Skin Tumors, Ecology, Mathematical model, Simulation and Modeling, Crispr, Signaling cascades, Response to treatment, medicine.anatomical_structure, Computational Theory and Mathematics, Oncology, 030220 oncology & carcinogenesis, Modeling and Simulation, Engineering and Technology, Synthetic Biology, Colorectal Neoplasms, Research Article, Proto-Oncogene Proteins B-raf, Cell biology, MAPK signaling cascades, Signal Inhibition, QH301-705.5, Bioengineering, Antineoplastic Agents, Computational biology, Dermatology, Research and Analysis Methods, 03 medical and health sciences, Cellular and Molecular Neuroscience, Cell Line, Tumor, Genetics, medicine, Humans, In patient, Protein kinase A, Molecular Biology, Ecology, Evolution, Behavior and Systematics, Colorectal Cancer, Biology and life sciences, Cancer, Cancers and Neoplasms, Computational Biology, Genetic Therapy, Synthetic Genomics, medicine.disease, Omics, 030104 developmental biology, Cell culture, CRISPR-Cas Systems, Transcriptome, Signalling pathways
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المؤلفون: A. Abakar Mahamat, N. Mathé, Roger Faroux, R. Boustany, P. Soulié, L. Moreau, Isabelle Baumgaertner, R. Hervé, J. M. Phelip, D. Smith, J. M. Bons, L. Vazquez, Laurent Miglianico, Eric Francois, Rosine Guimbaud, Laurent Mineur, Louis-Marie Dourthe, A. L. Villing, S. Remy, E. Achille, N. Bonichon, Carine Plassot, I. Rabbia
المصدر: PLoS ONE
PLoS ONE, Vol 15, Iss 12, p e0243997 (2020)مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Colorectal cancer, Cancer Treatment, ECOG Performance Status, Cetuximab, medicine.disease_cause, Toxicology, Pathology and Laboratory Medicine, Metastasis, 0302 clinical medicine, Antineoplastic Agents, Immunological, Basic Cancer Research, Medicine and Health Sciences, Neoplasm Metastasis, Paronychia, Aged, 80 and over, Univariate analysis, Multidisciplinary, Hazard ratio, Smoking, Middle Aged, Tumor Resection, Primary tumor, Surgical Oncology, Treatment Outcome, 030220 oncology & carcinogenesis, Medicine, Female, KRAS, Colorectal Neoplasms, medicine.drug, Research Article, Compliance, Clinical Oncology, Adult, medicine.medical_specialty, Science, Surgical and Invasive Medical Procedures, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, Malignant Tumors, Internal medicine, medicine, Humans, neoplasms, Aged, Colorectal Cancer, Folliculitis, Toxicity, Surgical Resection, business.industry, Proportional hazards model, Cancers and Neoplasms, Biology and Life Sciences, medicine.disease, digestive system diseases, 030104 developmental biology, Clinical Medicine, business
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المؤلفون: Clara Benna, Alessandra Comparato, Salvatore Pucciarelli, Andrea Errico, Isacco Maretto, Marina Bortolami, Fabio Farinati, Umberto Cillo
المصدر: PLoS ONE
PLoS ONE, Vol 15, Iss 12, p e0244356 (2020)مصطلحات موضوعية: 0301 basic medicine, Male, Cirrhosis, Colorectal cancer, Protein Expression, Cancer Treatment, Gene Expression, medicine.disease_cause, mTOR, LC3, p62, HCC, autophagy, Metastasis, 0302 clinical medicine, Gene expression, Basic Cancer Research, LC3, Medicine and Health Sciences, Tumor Microenvironment, HCC, Phosphorylation, Multidisciplinary, Cell Death, Liver Diseases, TOR Serine-Threonine Kinases, p62, Liver Neoplasms, Middle Aged, Gene Expression Regulation, Neoplastic, Surgical Oncology, Oncology, Cell Processes, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, mTOR, Medicine, Female, Colorectal Neoplasms, Microtubule-Associated Proteins, Research Article, Clinical Oncology, Adult, autophagy, Carcinoma, Hepatocellular, Science, Autophagic Cell Death, Down-Regulation, Gastroenterology and Hepatology, Research and Analysis Methods, Diagnosis, Differential, 03 medical and health sciences, Gastrointestinal Tumors, medicine, Gene Expression and Vector Techniques, Genetics, Humans, Molecular Biology Techniques, Molecular Biology, PI3K/AKT/mTOR pathway, Aged, Colorectal Cancer, Molecular Biology Assays and Analysis Techniques, business.industry, Autophagy, Carcinoma, Cancers and Neoplasms, Biology and Life Sciences, Hepatocellular Carcinoma, Cell Biology, medicine.disease, 030104 developmental biology, Case-Control Studies, Cancer research, Clinical Medicine, Carcinogenesis, business
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المؤلفون: Kuan Yan, Bahar Ramezanpour, Leo S. Price, Christina Esdar, Mairian Thomas, Hans-Peter Buchstaller, Marc Naven, Trevor Clive Dale, Jennifer R. Shone, Paul Shaw, Kenneth Burnside Ramsay Ewan, Luned Badder, J. Mark Treherne, Delyth A. Badder, Sylvia F. Boj, Kevin E. Ashelford, Rachel Hargest, Bram Herpers, Andrew John Hollins, Dirk Wienke, Alan Richard Clarke
المصدر: PLoS ONE, Vol 15, Iss 8, p e0235319 (2020)
PLoS ONEمصطلحات موضوعية: 0301 basic medicine, Male, Colorectal cancer, medicine.medical_treatment, Mice, SCID, Mice, 0302 clinical medicine, Cell Signaling, Mice, Inbred NOD, Gastrointestinal Cancers, Medicine and Health Sciences, Organ Cultures, Enzyme Inhibitors, WNT Signaling Cascade, Tankyrases, Multidisciplinary, Drug discovery, Stem Cell Therapy, Wnt signaling pathway, Stem-cell therapy, Phenotype, Signaling Cascades, Organoids, Oncology, 030220 oncology & carcinogenesis, Neoplastic Stem Cells, Medicine, Female, Biological Cultures, Colorectal Neoplasms, Research Article, Signal Transduction, Adult, Signal Inhibition, Imaging Techniques, Science, Antineoplastic Agents, Gastroenterology and Hepatology, Biology, Research and Analysis Methods, 03 medical and health sciences, Imaging, Three-Dimensional, Cancer stem cell, medicine, Organoid, Animals, Humans, Colorectal Cancer, Clinical Genetics, Morphometry, Cancers and Neoplasms, Biology and Life Sciences, Cell Biology, medicine.disease, 030104 developmental biology, Cancer cell, Cancer research
وصف الملف: application/pdf
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المؤلفون: Fatima Noor, Muhammad Hamzah Saleem, Jen-Tsung Chen, Muhammad Rizwan Javed, Wafa Abdullah Al-Megrin, Sidra Aslam
المصدر: PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0254678 (2021)مصطلحات موضوعية: 0301 basic medicine, Male, Skin Neoplasms, Pathogenesis, Pathology and Laboratory Medicine, Biochemistry, Database and Informatics Methods, 0302 clinical medicine, Mathematical and Statistical Techniques, Medicine and Health Sciences, Cell Cycle and Cell Division, Skin Tumors, Multidisciplinary, Gene Ontologies, Statistics, Genomics, Survival Rate, Paget Disease, Extramammary, Pharmaceutical Preparations, Oncology, Cell Processes, Research Design, 030220 oncology & carcinogenesis, Physical Sciences, Scrotum, Medicine, Genital Diseases, Male, Databases, Nucleic Acid, Research Article, Bioinformatics, Clinical Research Design, Science, Dermatology, Research and Analysis Methods, Disease-Free Survival, 03 medical and health sciences, Genetics, Humans, Statistical Methods, Colorectal Cancer, Gene Expression Profiling, Cancers and Neoplasms, Biology and Life Sciences, Computational Biology, Cell Biology, Genome Analysis, Survival Analysis, 030104 developmental biology, Gene Expression Regulation, Biomarkers, Mathematics
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المؤلفون: Pornchai Rojsitthisak, Koichi Matsuda, Watchara Sakares, Chizu Tanikawa, Varalee Yodsurang, Muttarin Lothong
المصدر: PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0255179 (2021)مصطلحات موضوعية: 0301 basic medicine, Cancer Treatment, Biochemistry, Autoantigens, Lung and Intrathoracic Tumors, 0302 clinical medicine, Antibiotics, Breast Tumors, Gastrointestinal Cancers, Medicine and Health Sciences, Post-Translational Modification, Phosphorylation, Multidisciplinary, Chemistry, Antimicrobials, TOR Serine-Threonine Kinases, Drugs, Non-Fibrillar Collagens, Gene Expression Regulation, Neoplastic, Oncology, Cell Processes, 030220 oncology & carcinogenesis, Doxycycline, Disease Progression, Medicine, Female, Research Article, Signal Transduction, Science, Breast Neoplasms, Gastroenterology and Hepatology, Microbiology, Models, Biological, 03 medical and health sciences, Antimalarials, Breast cancer, In vivo, Microbial Control, Spheroids, Cellular, Breast Cancer, medicine, Humans, Protein kinase B, PI3K/AKT/mTOR pathway, Cell Proliferation, Proportional Hazards Models, Colorectal Cancer, Pharmacology, Cell growth, Cancers and Neoplasms, Biology and Life Sciences, Proteins, Cell Biology, medicine.disease, Survival Analysis, In vitro, Clone Cells, 030104 developmental biology, Ki-67 Antigen, Tumor progression, Multivariate Analysis, Cancer research, Proto-Oncogene Proteins c-akt
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المؤلفون: Rana I. Elstaty, Mohammad Alqudah, Asem Alkhateeb, Maha S. Al-Keilani
المصدر: PLoS ONE
PLoS ONE, Vol 16, Iss 6, p e0252616 (2021)مصطلحات موضوعية: 0301 basic medicine, Cancer Treatment, Substance P, Gastroenterology, Biochemistry, Metastasis, chemistry.chemical_compound, 0302 clinical medicine, Breast Tumors, Basic Cancer Research, Medicine and Health Sciences, Medicine, Aged, 80 and over, Multidisciplinary, Tissue microarray, biology, Pharmaceutics, Hormonal Therapy, Middle Aged, Prognosis, Immunohistochemistry, Oncology, Receptors, Estrogen, 030220 oncology & carcinogenesis, Ki-67, Lymphatic Metastasis, Hormonal therapy, Female, Anatomy, Receptors, Progesterone, Research Article, Adult, medicine.medical_specialty, Science, Breast Neoplasms, Research and Analysis Methods, Lymphatic System, 03 medical and health sciences, Breast cancer, Drug Therapy, Internal medicine, Breast Cancer, Humans, Immunohistochemistry Techniques, Aged, Neoplasm Staging, Retrospective Studies, Colorectal Cancer, business.industry, Cancer, Cancers and Neoplasms, Biology and Life Sciences, medicine.disease, Histochemistry and Cytochemistry Techniques, 030104 developmental biology, Ki-67 Antigen, chemistry, biology.protein, Immunologic Techniques, Lymph Nodes, Neoplasm Grading, business, Biomarkers
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المؤلفون: Zeng-Hong Wu, Ming Fang, Yan Zhou
المصدر: PLoS ONE
PLoS ONE, Vol 15, Iss 7, p e0236678 (2020)مصطلحات موضوعية: 0301 basic medicine, Databases, Factual, Colorectal cancer, Gene Expression, Cell Cycle Proteins, Kaplan-Meier Estimate, CD8-Positive T-Lymphocytes, Lung and Intrathoracic Tumors, Prostate cancer, 0302 clinical medicine, Gene expression, Breast Tumors, Medicine and Health Sciences, Medicine, Regulation of gene expression, Multidisciplinary, Nasopharyngeal Carcinoma, Prostate Cancer, Prostate Diseases, Prognosis, Head and Neck Tumors, Gene Expression Regulation, Neoplastic, Oncology, Head and Neck Neoplasms, 030220 oncology & carcinogenesis, Biomarker (medicine), Research Article, Science, Urology, 03 medical and health sciences, Head and Neck Squamous Cell Carcinoma, stomatognathic system, Breast Cancer, otorhinolaryngologic diseases, Genetics, Biomarkers, Tumor, Humans, Squamous Cell Carcinoma, RNA, Messenger, Proportional Hazards Models, Colorectal Cancer, business.industry, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Cancers and Neoplasms, Biology and Life Sciences, medicine.disease, Head and neck squamous-cell carcinoma, stomatognathic diseases, Genitourinary Tract Tumors, Cytoskeletal Proteins, 030104 developmental biology, Nasopharyngeal carcinoma, Head and Neck Cancers, Cancer research, business, CD8
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