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المؤلفون: Dangxiao Cheng, Zhuo Chen, Henry Thai, Trevor Morey, Laurie Ailles, Osvaldo Espin-Garcia, Joerg Schwock, Lucy Liu, Helen Mackay, Hala Girgis, Jennifer Teichman, Geoffrey Liu, Andrew Fleet, Gail Darling, Wei Xu, Madison McGregor, Yuyao Song, Robert G. Bristow, Yonathan Brhane, Lorin Dodbiba
المصدر: PLoS ONE
Teichman, J, Dodbiba, L, Thai, H, Fleet, A, Morey, T, Liu, L, McGregor, M, Cheng, D, Chen, Z, Darling, G, Brhane, Y, Song, Y, Espin-Garcia, O, Xu, W, Girgis, H, Schwock, J, MacKay, H, Bristow, R, Ailles, L & Liu, G 2018, ' Hedgehog inhibition mediates radiation sensitivity in mouse xenograft models of human esophageal adenocarcinoma ', PLoS ONE, vol. 13, no. 5, pp. e0194809 . https://doi.org/10.1371/journal.pone.0194809
PLoS ONE, Vol 13, Iss 5, p e0194809 (2018)مصطلحات موضوعية: 0301 basic medicine, Cancer Treatment, lcsh:Medicine, Gene Expression, Mice, SCID, Epithelium, Cell Proliferation/drug effects, Mice, 0302 clinical medicine, Radiation sensitivity, Cell Signaling, Mice, Inbred NOD, Tumor Cells, Cultured, Medicine and Health Sciences, lcsh:Science, Pyridines/pharmacology, Multidisciplinary, Manchester Cancer Research Centre, Chemistry, Pharmaceutics, Chemoradiotherapy, Animal Models, Esophageal cancer, Hedgehog signaling pathway, medicine.anatomical_structure, Oncology, Experimental Organism Systems, 030220 oncology & carcinogenesis, Monoclonal, Signal transduction, Esophageal Neoplasms/drug therapy, Anatomy, Research Article, Signal Transduction, Hedgehog Proteins/antagonists & inhibitors, Clinical Oncology, endocrine system, Radiation Therapy, Mouse Models, Radiation Tolerance/drug effects, Research and Analysis Methods, 03 medical and health sciences, Cancer Chemotherapy, Model Organisms, Esophagus, Drug Therapy, Adenocarcinoma/drug therapy, Radioresistance, medicine, Genetics, Animals, Humans, Chemotherapy, Hedgehog, ResearchInstitutes_Networks_Beacons/mcrc, lcsh:R, Apoptosis/drug effects, Biology and Life Sciences, Cell Biology, medicine.disease, Xenograft Model Antitumor Assays, Gastrointestinal Tract, 030104 developmental biology, Biological Tissue, Gene Expression Regulation, Neoplastic/drug effects, Cancer research, Hedgehog Signaling, lcsh:Q, Biphenyl Compounds/pharmacology, Clinical Medicine, Combination Chemotherapy, Digestive System
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المؤلفون: Pedro Ratto Lisboa Pires, Edson Roberto Da Silva, Daniel De Carvalho, Ricardo Strefezzi, Heidge Fukumasu, Arina Rochetti, Maria Dagli, Lígia Garcia Mesquita
المصدر: PLoS ONE
Fukumasu, H, Rochetti, A L, Pires, P R L, Silva, E R, Mesquita, L G, Strefezzi, R F, De Carvalho, D D & Dagli, M L 2014, ' Constitutive androstane receptor ligands modulate the anti-tumor efficacy of paclitaxel in non-small cell lung cancer cells ', PLoS ONE, vol. 9, no. 6, e99484 . https://doi.org/10.1371/journal.pone.0099484
PLoS ONE, Vol 9, Iss 6, p e99484 (2014)مصطلحات موضوعية: Androstenols/pharmacology, Lung Neoplasms, Pyridines, Cancer Treatment, Gene Expression, Receptors, Cytoplasmic and Nuclear, Pharmacology, Lung and Intrathoracic Tumors, chemistry.chemical_compound, Mice, Computational Chemistry, Carcinoma, Non-Small-Cell Lung, Constitutive androstane receptor, Molecular Cell Biology, Basic Cancer Research, Oximes, Medicine and Health Sciences, WT1 Proteins/metabolism, Drug Interactions, Receptor, DNA Modification Methylases, Pyridines/pharmacology, Androstenols, Carcinoma, Non-Small-Cell Lung/metabolism, Multidisciplinary, Cell Death, Drug Synergism, Paclitaxel/pharmacology, Gene Expression Regulation, Neoplastic, Chemistry, Paclitaxel, Oncology, Cell Processes, Physical Sciences, Medicine, Oncology Agents, Antineoplastic Agents/pharmacology, Research Article, Drug Research and Development, Science, Antineoplastic Agents, Oximes/pharmacology, Receptors, Cytoplasmic and Nuclear/agonists, Cell Growth, Cell Line, Tumor, Thiazoles/pharmacology, medicine, Adenocarcinoma of the lung, Carcinoma, Genetics, Animals, Humans, Lung cancer, WT1 Proteins, Constitutive Androstane Receptor, business.industry, Cancer, Biology and Life Sciences, Computational Biology, Cancers and Neoplasms, Cell Biology, medicine.disease, Thiazoles, DNA Modification Methylases/metabolism, chemistry, Pharmacodynamics, Gene Expression Regulation, Neoplastic/drug effects, Cancer cell, Lung Neoplasms/metabolism, Clinical Medicine, business
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