المؤلفون: McBride A; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.; Brighton and Sussex Medical School, Brighton, United Kingdom.; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Duyen HTL; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam., Vuong NL; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.; University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam., Tho PV; Hospital for Tropical Disease, Ho Chi Minh City, Vietnam., Tai LTH; Hospital for Tropical Disease, Ho Chi Minh City, Vietnam., Phong NT; Hospital for Tropical Disease, Ho Chi Minh City, Vietnam., Ngoc NT; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam., Yen LM; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam., Nhat PTH; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam., Vi TT; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam., Llewelyn MJ; Brighton and Sussex Medical School, Brighton, United Kingdom., Thwaites L; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Hao NV; Hospital for Tropical Disease, Ho Chi Minh City, Vietnam., Yacoub S; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.

المصدر: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 Mar 27; Vol. 18 (3), pp. e0012071. Date of Electronic Publication: 2024 Mar 27 (Print Publication: 2024).

نوع المنشور: Observational Study; Journal Article

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

مواضيع طبية MeSH: Shock, Septic* , Severe Dengue* , Sepsis*/complications, Adult ; Humans ; Syndecan-1 ; Prospective Studies ; Vietnam/epidemiology ; Interleukin-6 ; Biomarkers ; Ferritins ; Prognosis ; Intensive Care Units

المؤلفون: Nitinai N; Department of Internal Medicine, Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand., Nasomsong W; Department of Internal Medicine, Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand., Chuerboonchai W; Department of Internal Medicine, Ananda Mahidol Hospital, Lopburi, Thailand., Tweekittikul A; Department of Internal Medicine, Ananda Mahidol Hospital, Lopburi, Thailand., Khingmontri V; Department of Internal Medicine, Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand.; Department of Internal Medicine, Ananda Mahidol Hospital, Lopburi, Thailand., Panuvatvanich B; Department of Internal Medicine, Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand.; Department of Internal Medicine, Ananda Mahidol Hospital, Lopburi, Thailand., Bangchuad T; Department of Internal Medicine, Fort Suranari Hospital, Nakhon Ratchasima, Thailand., Pongpraijaroen M; Department of Internal Medicine, Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand.; Department of Internal Medicine, Fort Suranari Hospital, Nakhon Ratchasima, Thailand., Roongfa-Ngarm T; Department of Internal Medicine, Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand.; Department of Internal Medicine, Fort Suranari Hospital, Nakhon Ratchasima, Thailand., Vasikasin V; Department of Internal Medicine, Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand.; Department of Internal Medicine, Ananda Mahidol Hospital, Lopburi, Thailand.

المصدر: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 Feb 02; Vol. 18 (2), pp. e0011927. Date of Electronic Publication: 2024 Feb 02 (Print Publication: 2024).

نوع المنشور: Randomized Controlled Trial; Multicenter Study; Journal Article

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

مواضيع طبية MeSH: Acetates*/therapeutic use , Severe Dengue* , Cyclopropanes* , Quinolines* , Sulfides*, Adult ; Humans ; Treatment Outcome ; Double-Blind Method ; Transaminases

المؤلفون: Recker M; Institute for Tropical Medicine, University Hospital Tübingen, Tübingen, Germany.; Centre for Ecology and Conservation, University of Exeter, Penryn Campus, Penryn, United Kingdom., Fleischmann WA; Institute for Tropical Medicine, University Hospital Tübingen, Tübingen, Germany., Nghia TH; 103 Military Hospital, Vietnam Military Medical University, Hanoi, Vietnam., Truong NV; 103 Military Hospital, Vietnam Military Medical University, Hanoi, Vietnam., Nam LV; 103 Military Hospital, Vietnam Military Medical University, Hanoi, Vietnam., Duc Anh D; Institute for Tropical Medicine, University Hospital Tübingen, Tübingen, Germany.; Vietnamese-German Center for Medical Research, VG-CARE, Hanoi, Vietnam., Song LH; Vietnamese-German Center for Medical Research, VG-CARE, Hanoi, Vietnam.; 108 Military Central Hospital, Hanoi, Vietnam., The NT; Vietnamese-German Center for Medical Research, VG-CARE, Hanoi, Vietnam.; 108 Military Central Hospital, Hanoi, Vietnam., Anh CX; 108 Military Central Hospital, Hanoi, Vietnam., Hoang NV; 108 Military Central Hospital, Hanoi, Vietnam., My Truong N; Vietnamese-German Center for Medical Research, VG-CARE, Hanoi, Vietnam.; 108 Military Central Hospital, Hanoi, Vietnam., Toan NL; Vietnamese-German Center for Medical Research, VG-CARE, Hanoi, Vietnam.; Department of Pathophysiology, Vietnam Military Medical University, Hanoi, Vietnam., Kremsner PG; Institute for Tropical Medicine, University Hospital Tübingen, Tübingen, Germany.; Centre de Recherches Médicales de Lambaréné (CERMEL), Gabon., Velavan TP; Institute for Tropical Medicine, University Hospital Tübingen, Tübingen, Germany.; Vietnamese-German Center for Medical Research, VG-CARE, Hanoi, Vietnam.; Faculty of Medicine, Duy Tan University, Da Nang, Vietnam.

المصدر: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 Jan 30; Vol. 18 (1), pp. e0011922. Date of Electronic Publication: 2024 Jan 30 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

مواضيع طبية MeSH: Severe Dengue*/diagnosis , Severe Dengue*/epidemiology, Humans ; Retrospective Studies ; Hospitalization ; Length of Stay ; Biomarkers

المؤلفون: Idrus NL; Department of Emergency Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur, Malaysia.; Emergency and Trauma Department, Hospital Bukit Mertajam, Jalan Kulim, Bukit Mertajam, Pulau Pinang, Malaysia., Md Jamal S; Department of Emergency Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur, Malaysia., Abu Bakar A; Department of Emergency Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur, Malaysia., Embong H; Department of Emergency Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur, Malaysia., Ahmad NS; Department of Emergency Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur, Malaysia.

المصدر: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2023 Dec 19; Vol. 17 (12), pp. e0011839. Date of Electronic Publication: 2023 Dec 19 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

مواضيع طبية MeSH: Severe Dengue*/diagnosis , Dengue*/diagnosis, Humans ; Child ; Retrospective Studies ; Ascites ; Lethargy ; Hepatomegaly

المؤلفون: Annan E; Center for Health and Wellbeing, School of Public and International Affairs, Princeton University, Princeton, New Jersey, United States of America., Treviño J; Department of Urban Affairs at the School of Architecture, Universidad Autónoma de Nuevo León, San Nicolás de los Garza, Nuevo Léon, México., Zhao B; Department of Statistics and Data Science, The Wharton School, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Rodriguez-Morales AJ; Faculty of Health Sciences, Universidad Científica del Sur, Lima, Peru.; Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Beirut, Lebanon.; Grupo de Investigación Biomedicina, Faculty of Medicine, Fundación Universitaria Autónoma de las Américas-Institución Universitaria Visión de las Américas, Pereira, Risaralda, Colombia., Haque U; Rutgers Global Health Institute, New Brunswick, New Jersey, United States of America.; Department of Biostatistics and Epidemiology, School of Public Health, Rutgers University, Piscataway, New Jersey, United States of America.

المصدر: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2023 Aug 09; Vol. 17 (8), pp. e0011537. Date of Electronic Publication: 2023 Aug 09 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

مواضيع طبية MeSH: Severe Dengue*/epidemiology , Dengue*/epidemiology , Dengue Virus* , Coinfection*/epidemiology, Infant ; Humans ; Aged ; Serogroup ; Antibodies, Viral

المؤلفون: Copaja-Corzo C; Unidad de Investigación para la Generación y Síntesis de Evidencias en Salud, Universidad San Ignacio de Loyola, Lima, Perú.; Servicio de Infectología, Hospital Nacional Edgardo Rebagliati Martins, EsSalud, Lima, Perú., Flores-Cohaila J; Facultad de Ciencias de la Salud, Universidad Científica del Sur, Lima, Perú., Tapia-Sequeiros G; Diagnóstico, Tratamiento e Investigación de Enfermedades Infecciosas y Tropicales, Universidad Privada de Tacna, Tacna, Perú., Vilchez-Cornejo J; Facultad de Salud Pública y Administración, Unidad de Investigación de Enfermedades Emergentes y Cambio Climático, Universidad Peruana Cayetano Heredia, Lima, Perú., Hueda-Zavaleta M; Diagnóstico, Tratamiento e Investigación de Enfermedades Infecciosas y Tropicales, Universidad Privada de Tacna, Tacna, Perú., Vilcarromero S; Servicio de Infectología, Hospital Nacional Edgardo Rebagliati Martins, EsSalud, Lima, Perú., Santana-Téllez T; Hospital II Pucallpa, EsSalud, Ucayali, Perú.; Facultad de Ciencias de la Salud, Universidad Nacional de Ucayali, Ucayali, Perú., Parodi JF; Facultad de Medicina Humana, Centro de Investigación del Envejecimiento (CIEN), Universidad de San Martín de Porres, Lima, Perú., Gomez-Colque S; Facultad de Ciencias de la Salud, Universidad Nacional Jorge Basadre Grohmann, Tacna, Perú., Benites-Zapata VA; Unidad de Investigación para la Generación y Síntesis de Evidencias en Salud, Universidad San Ignacio de Loyola, Lima, Perú.

المصدر: PloS one [PLoS One] 2024 Jun 25; Vol. 19 (6), pp. e0305689. Date of Electronic Publication: 2024 Jun 25 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Dengue*/epidemiology , Dengue*/mortality, Humans ; Peru/epidemiology ; Risk Factors ; Male ; Adult ; Female ; Middle Aged ; Retrospective Studies ; Adolescent ; Young Adult ; Child ; Intensive Care Units ; Severe Dengue/epidemiology ; Severe Dengue/mortality ; Prognosis ; Cohort Studies

المؤلفون: Lu HZ; Department of Pathogen Biology, Anhui Province Key Laboratory of Zoonoses, the Key Laboratory of Zoonoses of High Institutions in Anhui, School of Basic Medical Sciences, Anhui Medical University, Hefei, China.; Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui China., Xie YZ; Department of Pathogen Biology, Anhui Province Key Laboratory of Zoonoses, the Key Laboratory of Zoonoses of High Institutions in Anhui, School of Basic Medical Sciences, Anhui Medical University, Hefei, China., Gao C; Department of Pathogen Biology, Anhui Province Key Laboratory of Zoonoses, the Key Laboratory of Zoonoses of High Institutions in Anhui, School of Basic Medical Sciences, Anhui Medical University, Hefei, China.; Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui China., Wang Y; Department of Tropical Medicine, College of Military Preventive Medicine, Army Medical University, Chongqing, China., Liu TT; Department of Tropical Medicine, College of Military Preventive Medicine, Army Medical University, Chongqing, China., Wu XZ; Department of Endocrinology, The First Affiliated Hospital of Anhui Medical University, Hefei, China., Dai F; Department of Endocrinology, The First Affiliated Hospital of Anhui Medical University, Hefei, China., Wang DQ; National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), National Health Commission Key Laboratory of Parasite and Vector Biology; WHO Collaborating Center for Tropical Diseases; National Center for International Research on Tropical Diseases, Shanghai, China., Deng SQ; Department of Pathogen Biology, Anhui Province Key Laboratory of Zoonoses, the Key Laboratory of Zoonoses of High Institutions in Anhui, School of Basic Medical Sciences, Anhui Medical University, Hefei, China.

المصدر: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 May 31; Vol. 18 (5), pp. e0012217. Date of Electronic Publication: 2024 May 31 (Print Publication: 2024).

نوع المنشور: Journal Article; Meta-Analysis

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

مواضيع طبية MeSH: West Nile Fever*/complications , West Nile Fever*/epidemiology , West Nile Fever*/mortality, Humans ; Risk Factors ; Severe Dengue/complications ; Severe Dengue/epidemiology ; Diabetes Mellitus/epidemiology ; Diabetes Complications

المؤلفون: Yang J; Ecosystem Change and Population Health Research Group, School of Public Health and Social Work, Queensland University of Technology, Brisbane, Australia.; College of Earth and Environmental Sciences, Lanzhou University, Lanzhou, China., Mosabbir AA; Department of Emerging and Neglected Diseases, Biomedical Research Foundation, Dhaka, Bangladesh., Raheem E; Department of Emerging and Neglected Diseases, Biomedical Research Foundation, Dhaka, Bangladesh., Hu W; Ecosystem Change and Population Health Research Group, School of Public Health and Social Work, Queensland University of Technology, Brisbane, Australia., Hossain MS; Department of Emerging and Neglected Diseases, Biomedical Research Foundation, Dhaka, Bangladesh.; School of Environment and Life Sciences, Independent University, Dhaka, Bangladesh.

المصدر: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2023 Mar 15; Vol. 17 (3), pp. e0011161. Date of Electronic Publication: 2023 Mar 15 (Print Publication: 2023).

نوع المنشور: Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

مواضيع طبية MeSH: Severe Dengue*/diagnosis , Severe Dengue*/epidemiology , Severe Dengue*/complications , Dengue*/diagnosis , Dengue*/epidemiology , Dengue*/etiology, Humans ; Child ; Bangladesh/epidemiology ; Logistic Models ; Hospitals ; Biomarkers ; Demography

المؤلفون: Carras M; Intensive Care Unit, CHU Réunion, Saint Pierre, Reunion, France., Maillard O; Department of Public Health and Research, CHU Réunion, Saint-Pierre, Reunion, France.; Clinical Investigation Center, INSERM CIC1410, CHU Réunion, Saint Pierre, Reunion, France., Cousty J; Intensive Care Unit, CHU Réunion, Saint Pierre, Reunion, France., Gérardin P; Department of Public Health and Research, CHU Réunion, Saint-Pierre, Reunion, France.; Clinical Investigation Center, INSERM CIC1410, CHU Réunion, Saint Pierre, Reunion, France., Boukerrou M; Department of Gynecology and Obstetrics, CHU Réunion, Saint Pierre, Reunion, France., Raffray L; Department of Internal Medicine, CHU Réunion, Saint Denis, Reunion, France.; UMR Processus Infectieux en Milieu Insulaire Tropical (PIMIT), CNRS 9192, INSERM 1187, IRD 249, Université de La Réunion, Sainte-Clotilde, Reunion, France., Mavingui P; UMR Processus Infectieux en Milieu Insulaire Tropical (PIMIT), CNRS 9192, INSERM 1187, IRD 249, Université de La Réunion, Sainte-Clotilde, Reunion, France., Poubeau P; Department of Infectious Diseases, CHU Réunion, Saint-Pierre, Reunion, France., Cabie A; Department of Infectious and Tropical Diseases, CHU Martinique, Fort-de-France, Martinique, France.; Clinical Investigation Center, INSERM CIC1424, CHU Martinique, Fort-de-France, Martinique, France., Bertolotti A; Clinical Investigation Center, INSERM CIC1410, CHU Réunion, Saint Pierre, Reunion, France.; Department of Infectious Diseases, CHU Réunion, Saint-Pierre, Reunion, France.

المصدر: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2023 Apr 17; Vol. 17 (4), pp. e0011260. Date of Electronic Publication: 2023 Apr 17 (Print Publication: 2023).

نوع المنشور: Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

مواضيع طبية MeSH: Severe Dengue*/diagnosis , Dengue*/epidemiology , Dengue*/diagnosis , Cardiovascular Diseases*, Humans ; Reunion/epidemiology ; Prospective Studies ; Dehydration ; Risk Factors

المؤلفون: Bernal C; Universidad Nacional de Asunción, Instituto de Investigaciones en Ciencias de la Salud, San Lorenzo, Paraguay., Ping S; Emory University School of Medicine, Division of Infectious Diseases, Atlanta, Georgia, United States of America., Rojas A; Universidad Nacional de Asunción, Instituto de Investigaciones en Ciencias de la Salud, San Lorenzo, Paraguay., Caballero O; Universidad Nacional de Asunción, Instituto de Investigaciones en Ciencias de la Salud, San Lorenzo, Paraguay., Stittleburg V; Emory University School of Medicine, Division of Infectious Diseases, Atlanta, Georgia, United States of America., de Guillén Y; Universidad Nacional de Asunción, Instituto de Investigaciones en Ciencias de la Salud, San Lorenzo, Paraguay., Langjahr P; Universidad Nacional de Asunción, Facultad de Ciencias Químicas, San Lorenzo, Paraguay., Pinsky BA; Department of Pathology, Stanford University School of Medicine, California, United States of America.; Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, California, United States of America., Von-Horoch M; Hospital Central-Instituto de Previsión Social, Departamento de Epidemiología, Asunción, Paraguay., Luraschi P; Hospital Central-Instituto de Previsión Social, Departamento de Epidemiología, Asunción, Paraguay., Cabral S; Hospital Central-Instituto de Previsión Social, Departamento de Epidemiología, Asunción, Paraguay., Sánchez MC; Hospital Central-Instituto de Previsión Social, Departamento de Laboratorio de Análisis Clínicos, Asunción, Paraguay., Torres A; Hospital Central-Instituto de Previsión Social, Departamento de Laboratorio de Análisis Clínicos, Asunción, Paraguay., Cardozo F; Universidad Nacional de Asunción, Instituto de Investigaciones en Ciencias de la Salud, San Lorenzo, Paraguay.; Hospital Central-Instituto de Previsión Social, Departamento de Laboratorio de Análisis Clínicos, Asunción, Paraguay., Waggoner JJ; Emory University School of Medicine, Division of Infectious Diseases, Atlanta, Georgia, United States of America.; Rollins School of Public Health, Department of Global Health, Atlanta, Georgia, United States of America.

المصدر: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2023 Feb 27; Vol. 17 (2), pp. e0010750. Date of Electronic Publication: 2023 Feb 27 (Print Publication: 2023).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

مواضيع طبية MeSH: Flavivirus* , Severe Dengue*/diagnosis, Adult ; Female ; Humans ; Antibodies, Viral ; Biomarkers ; Chymases ; Enzyme-Linked Immunosorbent Assay ; Immunoglobulin G ; Immunoglobulin M ; Male