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المؤلفون: Eleanor Mary Naudzius, Savanah Jessica Diaz, Madison Elle Walsh, Mikhail Martchenko, Danae Schulz, Theodore William Wismar
المصدر: PLoS Neglected Tropical Diseases, Vol 14, Iss 3, p e0007790 (2020)
PLoS Neglected Tropical Diseasesمصطلحات موضوعية: 0301 basic medicine, Life Cycles, RC955-962, Drug Evaluation, Preclinical, Spironolactone, Parasitic Cell Cycles, Spectrum Analysis Techniques, 0302 clinical medicine, Phenothiazines, Zoonoses, Arctic medicine. Tropical medicine, Medicine and Health Sciences, African trypanosomiasis, Procyclin, Protozoans, Pharmaceutics, Eukaryota, Gene Expression Regulation, Developmental, Cell Differentiation, Flow Cytometry, Trypanocidal Agents, Infectious Diseases, Spectrophotometry, Cytophotometry, Public aspects of medicine, RA1-1270, Research Article, medicine.drug, Trypanosoma, Eflornithine, Parasitic Life Cycles, Trypanosoma brucei brucei, 030231 tropical medicine, Library Screening, Biology, Trypanosoma brucei, Research and Analysis Methods, 03 medical and health sciences, Immune system, Drug Therapy, Trypanosomiasis, Trypanosoma Brucei, Parasitic Diseases, Antigenic variation, medicine, Molecular Biology Techniques, Molecular Biology, Pharmacology, Molecular Biology Assays and Analysis Techniques, Drug Screening, Protozoan Infections, fungi, Organisms, Drug Repositioning, Public Health, Environmental and Occupational Health, Biology and Life Sciences, medicine.disease, biology.organism_classification, Virology, Parasitic Protozoans, 030104 developmental biology, Parasitology, Developmental Biology, Trypanosoma Brucei Gambiense
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المؤلفون: Sarah A. Thomas, Lea Ann Dailey, Marcelo A. da Silva, Lisa Sanderson, Shanta J. Persaud, Margarita Valero, Simon L. Croft, Mark R. Christie, Hollie Burrell-Saward, Mehmet Fidanboylu, Chris Lorenz, Bo Liu, Cécile A. Dreiss, Rachel C. Brown, Gayathri N. Sekhar, Vanessa Yardley
المصدر: PLoS Neglected Tropical Diseases
Sanderson, L, Da Silva, M, Sekhar, G, Brown, R, Burrell-Saward, H, Fidanboylu, M, Liu, B, Dailey, L A, Dreiss, C, Lorenz, C, Christie, M, Persaud, S, Yardley, V, Croft, S, Valero, M & Thomas, S 2021, ' Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug ', PLoS Neglected Tropical Diseases, vol. 15, no. 4, e0009276 . https://doi.org/10.1371/journal.pntd.0009276
PLoS Neglected Tropical Diseases, Vol 15, Iss 4, p e0009276 (2021)مصطلحات موضوعية: Central Nervous System, Male, Trypanosoma brucei rhodesiense, 0301 basic medicine, Polymers, Physiology, Trypanosoma brucei gambiense, RC955-962, 02 engineering and technology, Pharmacology, Toxicology, Pathology and Laboratory Medicine, Nervous System, Mice, Endocrinology, Arctic medicine. Tropical medicine, Insulin Secretion, Medicine and Health Sciences, African trypanosomiasis, Materials, media_common, 0303 health sciences, Mice, Inbred BALB C, biology, Neglected Diseases, 021001 nanoscience & nanotechnology, Trypanocidal Agents, 3. Good health, Solutions, Chemistry, Infectious Diseases, Macromolecules, Blood-Brain Barrier, Physical Sciences, Toxicity, Female, Public aspects of medicine, RA1-1270, Anatomy, 0210 nano-technology, Research Article, medicine.drug, Drug, Tsetse Flies, media_common.quotation_subject, Materials Science, Material Properties, Trypanosoma brucei, Aqueous Solutions, NANOHAT, Permeability, 03 medical and health sciences, Pharmacokinetics, In vivo, medicine, Animals, Humans, Pentamidine, 030304 developmental biology, Endocrine Physiology, business.industry, Public Health, Environmental and Occupational Health, Neurotoxicity, Biology and Life Sciences, biology.organism_classification, Polymer Chemistry, medicine.disease, Trypanosomiasis, African, 030104 developmental biology, Mixtures, Saline Solutions, Nanocarriers, business
وصف الملف: application/pdf
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المؤلفون: Alexandra G. Raftery, Saloum Jallow, Jean Rodgers, D. G. M. Sutton
المصدر: PLoS Neglected Tropical Diseases, Vol 13, Iss 3, p e0007175 (2019)
PLoS Neglected Tropical Diseasesمصطلحات موضوعية: 0301 basic medicine, Male, Disease, Abortion, Arsenicals, law.invention, chemistry.chemical_compound, Diminazene, Random Allocation, 0302 clinical medicine, Randomized controlled trial, law, Zoonoses, Medicine and Health Sciences, Prospective Studies, Asses, Protozoans, Mammals, education.field_of_study, Pharmaceutics, Triazines, lcsh:Public aspects of medicine, Eukaryota, Trypanocidal Agents, Phenanthridines, Infectious Diseases, Treatment Outcome, Vertebrates, Female, Gambia, Isometamidium chloride, medicine.drug, Research Article, medicine.medical_specialty, Trypanosoma, lcsh:Arctic medicine. Tropical medicine, lcsh:RC955-962, 030231 tropical medicine, Population, Equines, 03 medical and health sciences, Pharmacotherapy, Drug Therapy, Trypanosomiasis, Internal medicine, medicine, Trypanosoma Brucei, Parasitic Diseases, Animals, Horses, education, Protozoan Infections, business.industry, Public Health, Environmental and Occupational Health, Organisms, Biology and Life Sciences, lcsh:RA1-1270, Equidae, medicine.disease, Parasitic Protozoans, 030104 developmental biology, chemistry, Amniotes, Horse Diseases, business, Trypanosoma Brucei Gambiense
وصف الملف: application/pdf
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المؤلفون: Sabine Kaltenbrunner, Hassan Hashimi, Alena Zíková, Julius Lukeš
المصدر: PLoS Pathogens, Vol 12, Iss 4, p e1005492 (2016)
PLoS Pathogensمصطلحات موضوعية: 0301 basic medicine, Mitochondrial translation, Gene Expression, Mitochondrion, Ribosome, Biochemistry, Pearls, SWEAT, Antibiotics, Protein biosynthesis, Medicine and Health Sciences, lcsh:QH301-705.5, Energy-Producing Organelles, Protozoans, biology, Antimicrobials, Drugs, Drug Resistance, Microbial, Anti-Bacterial Agents, Mitochondria, Nucleic acids, Ribosomal RNA, Tetracyclines, Cellular Structures and Organelles, medicine.drug, lcsh:Immunologic diseases. Allergy, Trypanosoma, Tetracycline, Immunology, Bioenergetics, Microbiology, 03 medical and health sciences, Virology, Microbial Control, medicine, Genetics, Non-coding RNA, Molecular Biology, Pharmacology, 030102 biochemistry & molecular biology, Organisms, Biology and Life Sciences, Cell Biology, biology.organism_classification, Molecular biology, Parasitic Protozoans, 030104 developmental biology, lcsh:Biology (General), Protein Biosynthesis, RNA, Parasitology, Protein Translation, lcsh:RC581-607, Ribosomes, Trypanosoma Brucei Gambiense
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