المؤلفون: Yu L; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China; Children's Hospital, Institutes of Reproduction and Development, Fudan University, Shanghai 201102, China; Department of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China., Wang L; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China; Boston Children's Hospital and NGS collaboration, Harvard Medical School, Boston MA 02115, USA; National Clinical Research Center for Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China. Electronic address: bwanglina@sina.com., Tao W; Obstetrics and Gynecology Hospital, NHC Key Laboratory of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), State Key Laboratory of Genetic Engineering at School of Life Sciences, Institute of Metabolism and Integrative Biology, Fudan University, Shanghai 200011, China; Institute of Developmental Biology & Molecular Medicine, Fudan University, Shanghai 200433, China., Zhang W; Boston Children's Hospital and NGS collaboration, Harvard Medical School, Boston MA 02115, USA; Reproductive Medicine Centre, Anhui Medical University, Hefei 230032, China., Yang S; Boston Children's Hospital and NGS collaboration, Harvard Medical School, Boston MA 02115, USA; Chigene Translational Medicine Research Center, Beijing 100875, China., Wang J; Boston Children's Hospital and NGS collaboration, Harvard Medical School, Boston MA 02115, USA; Shanghai Children's Medical Center, Shanghai Jiaotong University, Shanghai 200127, China., Fei J; Boston Children's Hospital and NGS collaboration, Harvard Medical School, Boston MA 02115, USA; Zhongke Genetics and Reproductive Medicine Institute, Beijing 102600, China., Peng R; Obstetrics and Gynecology Hospital, NHC Key Laboratory of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), State Key Laboratory of Genetic Engineering at School of Life Sciences, Institute of Metabolism and Integrative Biology, Fudan University, Shanghai 200011, China., Wu Y; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China; Children's Hospital, Institutes of Reproduction and Development, Fudan University, Shanghai 201102, China; Boston Children's Hospital and NGS collaboration, Harvard Medical School, Boston MA 02115, USA., Zhen X; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China; Boston Children's Hospital and NGS collaboration, Harvard Medical School, Boston MA 02115, USA; National Clinical Research Center for Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China., Shao H; Boston Children's Hospital and NGS collaboration, Harvard Medical School, Boston MA 02115, USA., Gu W; Boston Children's Hospital and NGS collaboration, Harvard Medical School, Boston MA 02115, USA; Chigene Translational Medicine Research Center, Beijing 100875, China., Li R; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China; National Clinical Research Center for Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China., Wu BL; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China; Children's Hospital, Institutes of Reproduction and Development, Fudan University, Shanghai 201102, China; Boston Children's Hospital and NGS collaboration, Harvard Medical School, Boston MA 02115, USA. Electronic address: Wu_b@fudan.edu.cn., Wang H; Children's Hospital, Institutes of Reproduction and Development, Fudan University, Shanghai 201102, China; Obstetrics and Gynecology Hospital, NHC Key Laboratory of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), State Key Laboratory of Genetic Engineering at School of Life Sciences, Institute of Metabolism and Integrative Biology, Fudan University, Shanghai 200011, China. Electronic address: wanghy@fudan.edu.cn.

المصدر: Journal of genetics and genomics = Yi chuan xue bao [J Genet Genomics] 2021 May 20; Vol. 48 (5), pp. 384-395. Date of Electronic Publication: 2021 May 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Science press Country of Publication: China NLM ID: 101304616 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1673-8527 (Print) Linking ISSN: 16738527 NLM ISO Abbreviation: J Genet Genomics Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Predisposition to Disease* , Mutation*, Polycystic Ovary Syndrome/*genetics , Receptors, LH/*genetics, Alleles ; Animals ; Biosynthetic Pathways ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; DNA Mutational Analysis ; Disease Models, Animal ; Female ; Gene Frequency ; Genetic Association Studies ; Humans ; Immunohistochemistry ; Mice ; Mice, Knockout ; Pedigree ; Phenotype ; Polycystic Ovary Syndrome/diagnosis ; Polycystic Ovary Syndrome/metabolism ; Receptors, LH/metabolism ; Steroids/biosynthesis ; Exome Sequencing