المؤلفون: Yee SW; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, 94158-2911, USA., Lin L; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, 94158-2911, USA., Merski M; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, 94158-2550, USA.; Instituto de Biologia Molecular e Celular, Universidade do Porto, 4150- 180, Porto, Portugal., Keiser MJ; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, 94158-2911, USA.; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, 94158-2550, USA.; Institute for Neurodegenerative Diseases, University of California San Francisco, San Francisco, CA, 94143, USA., Gupta A; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, 94158-2911, USA., Zhang Y; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, 94158-2911, USA., Chien HC; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, 94158-2911, USA., Shoichet BK; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, 94158-2550, USA., Giacomini KM; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, 94158-2911, USA. kathy.giacomini@ucsf.edu.

المصدر: Journal of pharmacokinetics and pharmacodynamics [J Pharmacokinet Pharmacodyn] 2015 Oct; Vol. 42 (5), pp. 463-75. Date of Electronic Publication: 2015 Sep 03.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 101096520 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-8744 (Electronic) Linking ISSN: 1567567X NLM ISO Abbreviation: J Pharmacokinet Pharmacodyn Subsets: MEDLINE

مواضيع طبية MeSH: Membrane Transport Proteins/*metabolism , Metformin/*metabolism, Amine Oxidase (Copper-Containing)/metabolism ; Biological Transport/physiology ; Cell Line ; Diabetes Mellitus, Type 2/metabolism ; HEK293 Cells ; Humans ; Intestinal Mucosa/metabolism ; Kinetics ; Octamer Transcription Factor-3/metabolism ; Organic Cation Transporter 1/metabolism ; Serotonin Plasma Membrane Transport Proteins/metabolism