المؤلفون: Cao S; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, USA. sjcao@uw.edu.; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA, USA. sjcao@uw.edu., Budina E; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, USA., Raczy MM; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, USA., Solanki A; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, USA.; Animal Resource Center, University of Chicago, Chicago, IL, USA., Nguyen M; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, USA.; Animal Resource Center, University of Chicago, Chicago, IL, USA., Beckman TN; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, USA., Reda JW; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, USA., Hultgren K; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, USA., Ang PS; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, USA., Slezak AJ; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, USA., Hesser LA; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, USA., Alpar AT; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, USA., Refvik KC; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, USA., Shores LS; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, USA., Pillai I; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, USA., Wallace RP; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, USA., Dhar A; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, USA., Watkins EA; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, USA., Hubbell JA; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, USA. jhubbell@uchicago.edu.; Committee on Immunology, University of Chicago, Chicago, IL, USA. jhubbell@uchicago.edu.; Committee on Cancer Biology, University of Chicago, Chicago, IL, USA. jhubbell@uchicago.edu.

المصدر: Nature biomedical engineering [Nat Biomed Eng] 2024 May; Vol. 8 (5), pp. 611-627. Date of Electronic Publication: 2024 Apr 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Nature Country of Publication: England NLM ID: 101696896 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2157-846X (Electronic) Linking ISSN: 2157846X NLM ISO Abbreviation: Nat Biomed Eng Subsets: MEDLINE

مواضيع طبية MeSH: Prodrugs*/pharmacology , Prodrugs*/therapeutic use , Prodrugs*/pharmacokinetics , Prodrugs*/chemistry , Serine*/metabolism , Butyrates*/pharmacology , Butyrates*/therapeutic use , Butyrates*/chemistry , Butyrates*/administration & dosage , Biological Availability* , Arthritis, Experimental*/drug therapy , Arthritis, Experimental*/immunology, Animals ; Mice ; Administration, Oral ; Arthritis, Rheumatoid/drug therapy ; Arthritis, Rheumatoid/immunology ; Encephalomyelitis, Autoimmune, Experimental/drug therapy ; Encephalomyelitis, Autoimmune, Experimental/immunology ; Mice, Inbred C57BL ; Neuroinflammatory Diseases/drug therapy ; Female