المؤلفون: Shao Y; Department of Neurosurgery, the Affiliated Wuxi People's Hospital of Nanjing Medical University, No. 299, Qingyang Road, Wuxi, 214023, China.; Wuxi Medical Center, Nanjing Medical University, Wuxi, China., Yang Z; Department of Neurosurgery, the Affiliated Wuxi People's Hospital of Nanjing Medical University, No. 299, Qingyang Road, Wuxi, 214023, China., Miao W; Department of Neurosurgery, the Affiliated Wuxi People's Hospital of Nanjing Medical University, No. 299, Qingyang Road, Wuxi, 214023, China., Yu X; Department of Neurosurgery, the Affiliated Wuxi People's Hospital of Nanjing Medical University, No. 299, Qingyang Road, Wuxi, 214023, China., Pu Y; Department of Neurosurgery, the Affiliated Wuxi People's Hospital of Nanjing Medical University, No. 299, Qingyang Road, Wuxi, 214023, China. 18751589586@163.com.

المصدر: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2024 Jun; Vol. 397 (6), pp. 4139-4151. Date of Electronic Publication: 2023 Nov 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: MicroRNAs*/genetics , MicroRNAs*/metabolism , Glioblastoma*/genetics , Glioblastoma*/pathology , Glioblastoma*/metabolism , Basic-Leucine Zipper Transcription Factors*/genetics , Basic-Leucine Zipper Transcription Factors*/metabolism , RNA, Circular*/genetics , RNA, Circular*/metabolism , Up-Regulation* , Cell Proliferation* , Brain Neoplasms*/genetics , Brain Neoplasms*/pathology , Brain Neoplasms*/metabolism , Cell Movement* , Mice, Nude* , Apoptosis*, Humans ; Animals ; Cell Line, Tumor ; Mice ; Gene Expression Regulation, Neoplastic ; Male ; Neoplasm Invasiveness ; Mice, Inbred BALB C ; Female

المؤلفون: Bihari S; College of Medicine and Public Health, Flinders University, GPO Box 2100, Adelaide, SA, 5001, Australia.; Intensive and Critical Care Unit, Flinders Medical Centre, Flinders Drive, Bedford Park, SA, 5042, Australia., Costell MH; GlaxoSmithKline (GSK), 1250 South Collegeville Road, Collegeville, PA, 19426-0989, USA., Bouchier T; College of Medicine and Public Health, Flinders University, GPO Box 2100, Adelaide, SA, 5001, Australia., Behm DJ; GlaxoSmithKline (GSK), 1250 South Collegeville Road, Collegeville, PA, 19426-0989, USA., Burgert M; GlaxoSmithKline (GSK), 1250 South Collegeville Road, Collegeville, PA, 19426-0989, USA., Ye G; GlaxoSmithKline (GSK), 1250 South Collegeville Road, Collegeville, PA, 19426-0989, USA., Bersten AD; College of Medicine and Public Health, Flinders University, GPO Box 2100, Adelaide, SA, 5001, Australia.; Intensive and Critical Care Unit, Flinders Medical Centre, Flinders Drive, Bedford Park, SA, 5042, Australia., Puukila S; College of Medicine and Public Health, Flinders University, GPO Box 2100, Adelaide, SA, 5001, Australia., Cavallaro E; College of Medicine and Public Health, Flinders University, GPO Box 2100, Adelaide, SA, 5001, Australia., Sprecher DL; GlaxoSmithKline (GSK), 1250 South Collegeville Road, Collegeville, PA, 19426-0989, USA., Dixon DL; College of Medicine and Public Health, Flinders University, GPO Box 2100, Adelaide, SA, 5001, Australia. dani.dixon@flinders.edu.au.; Intensive and Critical Care Unit, Flinders Medical Centre, Flinders Drive, Bedford Park, SA, 5042, Australia. dani.dixon@flinders.edu.au.

المصدر: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2024 May; Vol. 397 (5), pp. 3461-3475. Date of Electronic Publication: 2023 Nov 15.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: TRPV Cation Channels*/antagonists & inhibitors , TRPV Cation Channels*/metabolism , TRPV Cation Channels*/agonists , Rats, Sprague-Dawley* , Disease Models, Animal* , Lung Injury*/drug therapy , Lung Injury*/chemically induced , Lung Injury*/metabolism, Leucine/*analogs & derivatives, Animals ; Male ; Rats ; Lung/drug effects ; Lung/metabolism ; Lung/pathology ; Pulmonary Edema/chemically induced ; Pulmonary Edema/drug therapy ; Leucine/pharmacology ; Sulfonamides/pharmacology ; Dose-Response Relationship, Drug

المؤلفون: Köster KA; Department of Clinical Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.; DZHK Standort Hamburg, Kiel, Lübeck, Germany., Duque Escobar J; Department of Clinical Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.; DZHK Standort Hamburg, Kiel, Lübeck, Germany., Fietkau A; Department of Clinical Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany., Toledo R; Department of Clinical Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany., Oetjen E; Department of Clinical Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany. e.oetjen@uke.uni-hamburg.de.; DZHK Standort Hamburg, Kiel, Lübeck, Germany. e.oetjen@uke.uni-hamburg.de.; Institute of Pharmacy, University of Hamburg, Bundesstr. 45, 20146, Hamburg, Germany. e.oetjen@uke.uni-hamburg.de.

المصدر: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2023 Jun; Vol. 396 (6), pp. 1223-1233. Date of Electronic Publication: 2023 Jan 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Leucine Zippers* , MAP Kinase Kinase Kinases*/metabolism, Colforsin ; Cell Line ; Promoter Regions, Genetic ; Proto-Oncogene Proteins c-fos/genetics ; Proto-Oncogene Proteins c-fos/metabolism

المؤلفون: Dabbaghipour R; Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran., Ahmadi E; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran., Entezam M; Department of Medical Genetics, Shiraz University of Medical Sciences, Shiraz, Iran., Farzam OR; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran., Sohrabi S; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran., Jamali S; Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran., Sichani AS; Department of Medical Genetics, Shiraz University of Medical Sciences, Shiraz, Iran.; Department of Biology, Texas A&M University, College Station, TX, 77843, USA., Paydar H; Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran., Baradaran B; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. behzad_im@yahoo.com.; Department of Immunology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran. behzad_im@yahoo.com.

المصدر: Immunogenetics [Immunogenetics] 2024 Apr; Vol. 76 (2), pp. 75-91. Date of Electronic Publication: 2024 Feb 15.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Springer Verlag Country of Publication: United States NLM ID: 0420404 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1211 (Electronic) Linking ISSN: 00937711 NLM ISO Abbreviation: Immunogenetics Subsets: MEDLINE

مواضيع طبية MeSH: Repressor Proteins*/genetics , Repressor Proteins*/metabolism , Neoplasms*/therapy , Neoplasms*/metabolism, Humans ; Animals ; Mice ; Basic-Leucine Zipper Transcription Factors/genetics ; Basic-Leucine Zipper Transcription Factors/metabolism ; CD8-Positive T-Lymphocytes ; Dendritic Cells ; Carcinogenesis ; Mice, Inbred C57BL ; Mice, Knockout ; Tumor Microenvironment

المؤلفون: Moors TE; Section Clinical Neuroanatomy and Biobanking, Department of Anatomy and Neurosciences, Amsterdam UMC, Vrije University, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Program Neurodegeneration, Amsterdam, The Netherlands., Morella ML; Section Clinical Neuroanatomy and Biobanking, Department of Anatomy and Neurosciences, Amsterdam UMC, Vrije University, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Program Neurodegeneration, Amsterdam, The Netherlands., Bertran-Cobo C; Section Clinical Neuroanatomy and Biobanking, Department of Anatomy and Neurosciences, Amsterdam UMC, Vrije University, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Program Neurodegeneration, Amsterdam, The Netherlands., Geut H; Section Clinical Neuroanatomy and Biobanking, Department of Anatomy and Neurosciences, Amsterdam UMC, Vrije University, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Program Neurodegeneration, Amsterdam, The Netherlands., Udayar V; Roche Pharma Research and Early Development; Neuroscience and Rare Diseases Discovery and Translational Area, Roche Innovation Center, Basel, Switzerland., Timmermans-Huisman E; Section Clinical Neuroanatomy and Biobanking, Department of Anatomy and Neurosciences, Amsterdam UMC, Vrije University, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Program Neurodegeneration, Amsterdam, The Netherlands., Ingrassia AMT; Section Clinical Neuroanatomy and Biobanking, Department of Anatomy and Neurosciences, Amsterdam UMC, Vrije University, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Program Neurodegeneration, Amsterdam, The Netherlands., Brevé JJP; Section Clinical Neuroanatomy and Biobanking, Department of Anatomy and Neurosciences, Amsterdam UMC, Vrije University, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Program Neurodegeneration, Amsterdam, The Netherlands., Bol JGJM; Section Clinical Neuroanatomy and Biobanking, Department of Anatomy and Neurosciences, Amsterdam UMC, Vrije University, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Program Neurodegeneration, Amsterdam, The Netherlands., Bonifati V; Erasmus MC, Department of Clinical Genetics, University Medical Center Rotterdam, Rotterdam, The Netherlands., Jagasia R; Roche Pharma Research and Early Development; Neuroscience and Rare Diseases Discovery and Translational Area, Roche Innovation Center, Basel, Switzerland., van de Berg WDJ; Section Clinical Neuroanatomy and Biobanking, Department of Anatomy and Neurosciences, Amsterdam UMC, Vrije University, Amsterdam, The Netherlands. wdj.vandeberg@amsterdamumc.nl.; Amsterdam Neuroscience, Program Neurodegeneration, Amsterdam, The Netherlands. wdj.vandeberg@amsterdamumc.nl.

المصدر: Acta neuropathologica [Acta Neuropathol] 2024 Apr 06; Vol. 147 (1), pp. 67. Date of Electronic Publication: 2024 Apr 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE

مواضيع طبية MeSH: Lewy Body Disease*/pathology, Humans ; alpha-Synuclein/metabolism ; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/genetics ; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/metabolism ; Brain/pathology ; Dopaminergic Neurons/metabolism ; Lewy Bodies/pathology

المؤلفون: Li Y; Department of Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwulu, Xi'an, 710004, Shaanxi Province, China. li_yanlingyl@163.com., Gao J; Department of Anesthesiology, The First Hospital of YuLin, YuLin, 719000, Shaanxi Province, China., Liu C; Department of Geriatrics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an , Shaanxi Province, China., Bu N; Department of Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwulu, Xi'an, 710004, Shaanxi Province, China., Zhan S; Department of Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwulu, Xi'an, 710004, Shaanxi Province, China., Wu H; Department of Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwulu, Xi'an, 710004, Shaanxi Province, China., Zhang R; Department of Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwulu, Xi'an, 710004, Shaanxi Province, China., Sun H; Department of Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwulu, Xi'an, 710004, Shaanxi Province, China., Fan H; Department of Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwulu, Xi'an, 710004, Shaanxi Province, China.

المصدر: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2023 Nov; Vol. 396 (11), pp. 3163-3175. Date of Electronic Publication: 2023 May 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: PTEN Phosphohydrolase*/genetics , Reperfusion Injury*/prevention & control , Reperfusion Injury*/metabolism , Ubiquitin Thiolesterase*/genetics, Animals ; Mice ; Rats ; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors ; Infarction, Middle Cerebral Artery ; RNA, Small Interfering ; TOR Serine-Threonine Kinases/metabolism ; Transcription Factors ; Gene Knockdown Techniques

المؤلفون: Iovino L; Department of Biology, University of Padova, Padua, Italy., Giusti V; Department of Biology, University of Padova, Padua, Italy., Pischedda F; Department of Cellular, Computational and Integrative Biology-CIBIO, University of Trento, Trento, Italy., Giusto E; IRCCS San Camillo Hospital, Venice, Italy., Plotegher N; Department of Biology, University of Padova, Padua, Italy., Marte A; Department of Experimental Medicine, University of Genova, Genoa, Italy., Battisti I; Department of Biomedical Sciences, University of Padova, Padua, Italy., Di Iacovo A; Department of Biotechnology and Life Sciences, Center for Research in Neuroscience, University of Insubria, Varese, Italy., Marku A; Department of Pharmacological and Biomolecular Sciences, University of Milano, Milan, Italy., Piccoli G; Department of Cellular, Computational and Integrative Biology-CIBIO, University of Trento, Trento, Italy., Bandopadhyay R; Reta Lila Weston Institute of Neurological Studies, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK., Perego C; Department of Pharmacological and Biomolecular Sciences, University of Milano, Milan, Italy., Bonifacino T; Department of Pharmacy-DIFAR, University of Genova, Genoa, Italy., Bonanno G; Department of Pharmacy-DIFAR, University of Genova, Genoa, Italy.; IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Roseti C; Department of Biotechnology and Life Sciences, Center for Research in Neuroscience, University of Insubria, Varese, Italy., Bossi E; Department of Biotechnology and Life Sciences, Center for Research in Neuroscience, University of Insubria, Varese, Italy., Arrigoni G; Department of Biomedical Sciences, University of Padova, Padua, Italy., Bubacco L; Department of Biology, University of Padova, Padua, Italy., Greggio E; Department of Biology, University of Padova, Padua, Italy., Hilfiker S; Department of Anesthesiology and Department of Physiology, Pharmacology and Neuroscience, Rutgers New Jersey Medical School, Newark, NJ, USA., Civiero L; Department of Biology, University of Padova, Padua, Italy. laura.civiero@unipd.it.; IRCCS San Camillo Hospital, Venice, Italy. laura.civiero@unipd.it.; Centro Studi per la Neurodegenerazione (CESNE), University of Padova, Padua, Italy. laura.civiero@unipd.it.

المصدر: Acta neuropathologica [Acta Neuropathol] 2022 Jul; Vol. 144 (1), pp. 81-106. Date of Electronic Publication: 2022 May 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE

مواضيع طبية MeSH: Parkinson Disease*/pathology, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/*metabolism, Amino Acid Transport System X-AG ; Animals ; Glutamates ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/genetics ; Mice ; Mutation ; Neurons/pathology

المؤلفون: Cabezudo D; Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, Leuven Brain Institute, KU Leuven, Herestraat 49, box 1023, 3000, Leuven, Belgium., Tsafaras G; Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, Leuven Brain Institute, KU Leuven, Herestraat 49, box 1023, 3000, Leuven, Belgium., Van Acker E; Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, Leuven Brain Institute, KU Leuven, Herestraat 49, box 1023, 3000, Leuven, Belgium., Van den Haute C; Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, Leuven Brain Institute, KU Leuven, Herestraat 49, box 1023, 3000, Leuven, Belgium.; Leuven Viral Vector Core, Herestraat 49, box 1023, 3000, Leuven, Belgium., Baekelandt V; Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, Leuven Brain Institute, KU Leuven, Herestraat 49, box 1023, 3000, Leuven, Belgium. veerle.baekelandt@kuleuven.be.

المصدر: Acta neuropathologica [Acta Neuropathol] 2023 Aug; Vol. 146 (2), pp. 245-261. Date of Electronic Publication: 2023 Jun 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE

مواضيع طبية MeSH: Colitis*/chemically induced , Colitis*/genetics , Inflammatory Bowel Diseases*/genetics , Parkinson Disease*/pathology, Animals ; Mice ; Immunity ; Inflammation ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/genetics ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/metabolism ; Mice, Transgenic ; Mutation/genetics

المؤلفون: Shi C; Center for Kidney Disease, Second Affiliated Hospital of Nanjing Medical University, No. 262 N Zhongshan Road, Nanjing, 210003, Jiangsu, China., Wan Y; Center for Kidney Disease, Second Affiliated Hospital of Nanjing Medical University, No. 262 N Zhongshan Road, Nanjing, 210003, Jiangsu, China., He A; Center for Kidney Disease, Second Affiliated Hospital of Nanjing Medical University, No. 262 N Zhongshan Road, Nanjing, 210003, Jiangsu, China., Wu X; Center for Kidney Disease, Second Affiliated Hospital of Nanjing Medical University, No. 262 N Zhongshan Road, Nanjing, 210003, Jiangsu, China., Shen X; Center for Kidney Disease, Second Affiliated Hospital of Nanjing Medical University, No. 262 N Zhongshan Road, Nanjing, 210003, Jiangsu, China., Zhu X; Center for Kidney Disease, Second Affiliated Hospital of Nanjing Medical University, No. 262 N Zhongshan Road, Nanjing, 210003, Jiangsu, China., Yang J; Center for Kidney Disease, Second Affiliated Hospital of Nanjing Medical University, No. 262 N Zhongshan Road, Nanjing, 210003, Jiangsu, China. jwyang@njmu.edu.cn., Zhou Y; Center for Kidney Disease, Second Affiliated Hospital of Nanjing Medical University, No. 262 N Zhongshan Road, Nanjing, 210003, Jiangsu, China. zhouyang@njmu.edu.cn.

المصدر: Acta diabetologica [Acta Diabetol] 2023 Sep; Vol. 60 (9), pp. 1199-1207. Date of Electronic Publication: 2023 May 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 9200299 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-5233 (Electronic) Linking ISSN: 09405429 NLM ISO Abbreviation: Acta Diabetol Subsets: MEDLINE

مواضيع طبية MeSH: Diabetic Nephropathies*/diagnosis , Diabetic Nephropathies*/etiology , Diabetic Nephropathies*/metabolism , Diabetes Mellitus, Type 2*/metabolism, Humans ; Interleukin-18/metabolism ; Leucine/metabolism ; Kidney/metabolism ; Inflammation/metabolism ; Biomarkers/metabolism

المؤلفون: Fan Y; Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, DD1 5EH, UK., Nirujogi RS; Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, DD1 5EH, UK., Garrido A; Parkinson's Disease and Movement Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain., Ruiz-Martínez J; Group of Neurodegenerative Diseases, Biodonostia Research Institute, San Sebastian, Spain., Bergareche-Yarza A; Group of Neurodegenerative Diseases, Biodonostia Research Institute, San Sebastian, Spain., Mondragón-Rezola E; Group of Neurodegenerative Diseases, Biodonostia Research Institute, San Sebastian, Spain., Vinagre-Aragón A; Group of Neurodegenerative Diseases, Biodonostia Research Institute, San Sebastian, Spain., Croitoru I; Group of Neurodegenerative Diseases, Biodonostia Research Institute, San Sebastian, Spain., Gorostidi Pagola A; Group of Neurodegenerative Diseases, Biodonostia Research Institute, San Sebastian, Spain., Paternain Markinez L; Group of Neurodegenerative Diseases, Biodonostia Research Institute, San Sebastian, Spain., Alcalay R; Department of Neurology, Columbia University Medical Center, New York, NY, USA., Hickman RA; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA., Düring J; Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, DD1 5EH, UK., Gomes S; Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, DD1 5EH, UK., Pratuseviciute N; Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, DD1 5EH, UK., Padmanabhan S; The Michael J Fox Foundation for Parkinson's Research, New York, NY, USA., Valldeoriola F; Parkinson's Disease and Movement Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain., Pérez Sisqués L; Departament de Biomedicina, Facultat de Medicina I Ciències de La Salut, Institut de Neurociències, Universitat de Barcelona, Barcelona, Catalonia, Spain., Malagelada C; Departament de Biomedicina, Facultat de Medicina I Ciències de La Salut, Institut de Neurociències, Universitat de Barcelona, Barcelona, Catalonia, Spain.; Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain., Ximelis T; Neurological Tissue Bank of the Biobanc-Hospital Clinic-Institut D'Investigacions Biomediques August Pi I Sunyer (IDIBAPS), Barcelona, Spain., Molina Porcel L; Neurological Tissue Bank of the Biobanc-Hospital Clinic-Institut D'Investigacions Biomediques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic, Institut D'Investigacions Biomediques August Pi I Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain., Martí MJ; Parkinson's Disease and Movement Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain., Tolosa E; Parkinson's Disease and Movement Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain., Alessi DR; Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, DD1 5EH, UK., Sammler EM; Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, DD1 5EH, UK. e.m.sammler@dundee.ac.uk.; Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, DD1 9SY, UK. e.m.sammler@dundee.ac.uk.

المصدر: Acta neuropathologica [Acta Neuropathol] 2021 Sep; Vol. 142 (3), pp. 475-494. Date of Electronic Publication: 2021 Jun 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE

مواضيع طبية MeSH: Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/*genetics , Mutation/*genetics , Neutrophils/*metabolism , rab GTP-Binding Proteins/*genetics, Adult ; Aged ; Aged, 80 and over ; Autopsy ; Biomarkers ; Female ; Heterozygote ; Humans ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/antagonists & inhibitors ; Male ; Middle Aged ; Parkinson Disease/genetics ; Parkinson Disease/pathology ; Phosphorylation ; Protein Kinase Inhibitors/pharmacology ; Protein Processing, Post-Translational