نتائج البحث - "Ribonucleotide"

1

The consequences of DNA lesions for mitochondrial DNA maintenance

مصطلحات موضوعية: ribonucleotide incorporation, Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy), mitochondrial DNA, DNA replication, DNA polymerase γ, Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci), Mitochondria, DNA lesions

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::73938bbc07437185175c11f0a318f7b9
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-182679

2

A genetic screen pinpoints ribonucleotide reductase residues that sustain dNTP homeostasis and specifies a highly mutagenic type of dNTP imbalance

المؤلفون: Hans Hombauer, Maike Gross, Andrei Chabes, Sushma Sharma, Gloria X Reyes, Kerstin Gries, Jui-Hung Yuan, Rebecca C. Wade, Boyu Zhao, Tobias T. Schmidt

المصدر: Nucleic Acids Research

مصطلحات موضوعية: DNA Replication, Saccharomyces cerevisiae Proteins, Cell- och molekylärbiologi, Deoxyribonucleotides, DNA-Directed DNA Polymerase, Saccharomyces cerevisiae, Genome Integrity, Repair and Replication, Biology, medicine.disease_cause, DNA Mismatch Repair, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Ribonucleotide Reductases, Genetics, medicine, Homeostasis, heterocyclic compounds, Allele, skin and connective tissue diseases, Alleles, 030304 developmental biology, 0303 health sciences, Mutation, DNA replication, humanities, Deoxyribonucleoside, Ribonucleotide reductase, Biochemistry, chemistry, sense organs, 030217 neurology & neurosurgery, Intracellular, Cell and Molecular Biology, Genetic screen

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d592d25edb43717c08ca66aca1b16fa5
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-154182

3

Elimination of rNMPs from mitochondrial DNA has no effect on its stability

المؤلفون: Danielle L. Watt, Paulina H. Wanrooij, Liam J. Thompson, Katrin Kreisel, Anna-Lena Feldberg, Anna Karin Nilsson, Sushma Sharma, Anders R. Clausen, Clara Navarrete, Gustavo Carvalho, Andrei Chabes, Martin K. M. Engqvist, Phong Tran

المصدر: Proceedings of the National Academy of Sciences of the United States of America

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3535937b2dba6b4540da63128926842
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-171765

4

Rnr1, but not Rnr3, facilitates the sustained telomerase-dependent elongation of telomeres

المؤلفون: Gilad Grinberg, Lisette Marjavaara, Inbal Gazy, Sushma Sharma, Martin Kupiec, André Maicher, Keren Shemesh, Andrei Chabes

المصدر: PLoS Genetics
PLoS Genetics, Vol 13, Iss 10, p e1007082 (2017)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Telomerase, Synthesis Phase, Yeast and Fungal Models, Biochemistry, Electrophoretic Blotting, Annan medicinsk grundvetenskap, Fungal Reproduction, Cell Cycle and Cell Division, Other Basic Medicine, Genetics (clinical), Cellular Senescence, Gel Electrophoresis, Chromosome Biology, Biochemistry and Molecular Biology, Eukaryota, Telomere, Nucleic acids, Phenotypes, Ribonucleotide reductase, Telomeres, Experimental Organism Systems, Cell Processes, Saccharomyces Cerevisiae, Research Article, Senescence, DNA Replication, Chromosome Structure and Function, lcsh:QH426-470, DNA damage, Molecular Probe Techniques, Mycology, Biology, Research and Analysis Methods, Chromosomes, 03 medical and health sciences, Telomerase RNA component, Electrophoretic Techniques, Saccharomyces, Telomere Homeostasis, Model Organisms, Ribonucleotide Reductases, Genetics, Fungal Spores, Molecular Biology Techniques, Molecular Biology, Ecology, Evolution, Behavior and Systematics, DNA replication, Organisms, Fungi, Biology and Life Sciences, Cell Biology, DNA, Molecular biology, Yeast, lcsh:Genetics, 030104 developmental biology, Saccharomycetales, Southern Blot, Biokemi och molekylärbiologi

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fac4d44547c86c82210d4e6530664eb
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-141579

5

Hydroxyurea-Mediated Cytotoxicity Without Inhibition of Ribonucleotide Reductase

المؤلفون: Matan Cohen, Ziqing Kong, Stephen D. Bell, Andrei Chabes, Lisette Marjavaara, Li Phing Liew, Zun Yi Lim

المصدر: Cell Reports, Vol 17, Iss 6, Pp 1657-1670 (2016)
Cell Reports

مصطلحات موضوعية: 0301 basic medicine, Transcription, Genetic, archaea, Cell- och molekylärbiologi, 030106 microbiology, Eukaryotic DNA replication, DNA Primase, DNA replication, General Biochemistry, Genetics and Molecular Biology, Article, hydroxyurea, Substrate Specificity, Sulfolobus, DNA replication factor CDT1, 03 medical and health sciences, Replication factor C, Control of chromosome duplication, Bacterial Proteins, Ribonucleotide Reductases, RNA, Messenger, lcsh:QH301-705.5, S phase, biology, Nucleotides, Molecular biology, 3. Good health, Protein Subunits, 030104 developmental biology, Ribonucleotide reductase, DNA, Archaeal, lcsh:Biology (General), biology.protein, Origin recognition complex, DNA damage, replication fork, Gene Expression Regulation, Archaeal, Cell Division, Cell and Molecular Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf12e6c715c0a7a485ad1b5bd0d72ee5
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-127399

6

Class I Ribonucleotide Reductases : overall activity regulation, oligomerization, and drug targeting

المؤلفون: Jonna, Venkateswara Rao

مصطلحات موضوعية: Biochemistry and Molecular Biology, Ribonucleotide reductase, GEMMA, Allosteric regulation, Biokemi och molekylärbiologi

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b834ac3066b76704c306a26797049d15
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-133817

7

Telomere length kinetics assay (TELKA) sorts the telomere length maintenance (tlm) mutants into functional groups

المؤلفون: Martin Kupiec, Vera Babin, Linda Rubinstein, Yaniv Harari, Gabor Merenyi, Lior Ungar, Shay Ben-Aroya, Lisette Marjavaara, Andrei Chabes

المصدر: Nucleic Acids Research

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::240129b84a873aab9dc62d8b1d4da5a4
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-87935

8

Targeting the nucleotide metabolism of the mammalian pathogen Trypanosoma brucei

المؤلفون: Vodnala, Munender

مصطلحات موضوعية: nucleoside kinases, NTP, doexynucleotide metabolism, Biochemistry and Molecular Biology, RNR, mouser ribonucleotide reductase, adenosine kinase, Ara-A, F-Ara-A, allosteric regulation, dNTP, methylthioadenosine phosphorylase, thymidine kinase, Trypanosoma brucei, E. coli ribonucleotide reductase, Biokemi och molekylärbiologi, nucleosides

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::372d1ccea4caefb46d71a7026a6d4187
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-80904

9

S phase block following MEC1ATR inactivation occurs without severe dNTP depletion

المؤلفون: Gabor Merenyi, Andrei Chabes, Caroline Earp, Rita S. Cha, Samuel P. Rowbotham

المصدر: Biology Open
Biology Open, Vol 4, Iss 12, Pp 1739-1743 (2015)

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25658008be9182a14e5d311d721694be
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-111962

10

Mechanisms controlling DNA damage survival and mutation rates in budding yeast

المؤلفون: Wiberg, Jörgen

مصطلحات موضوعية: dNTPs, Annan medicinsk grundvetenskap, heterocyclic compounds, translesion synthesis, ribonucleotide reductase, Other Basic Medicine, TLS polymerases

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c75797bcc1b0c6d0c016cbf4e8285e89
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-54203

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