المؤلفون: Yoshihiro Sowa, Ryoko Nakanishi, Toshiyuki Sakai, Masafumi Taniwaki, Hitoji Uchiyama, Chihiro Shimazaki, Mayumi Yogosawa, Miki Wakada, Mano Horinaka

المصدر: Cancer Science. 101:728-734

مصطلحات موضوعية: musculoskeletal diseases, Antimetabolites, Antineoplastic, Cancer Research, Indoles, Jurkat cells, Jurkat Cells, chemistry.chemical_compound, immune system diseases, Cyclin-dependent kinase, parasitic diseases, Dihydrofolate reductase, medicine, Humans, heterocyclic compounds, Promoter Regions, Genetic, skin and connective tissue diseases, Protein Kinase Inhibitors, Gene knockdown, Dose-Response Relationship, Drug, biology, Kinase, Imidazoles, Drug Synergism, General Medicine, medicine.disease, Cyclin-Dependent Kinases, Tetrahydrofolate Dehydrogenase, Leukemia, Methotrexate, Oncology, chemistry, Purines, Antifolate, biology.protein, Cancer research, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d1b7979b8d284a4e351cb9f6c92257
https://doi.org/10.1111/j.1349-7006.2009.01449.x

المؤلفون: Fotini Tzortzatou

المصدر: Scandinavian Journal of Haematology. 19:5-13

مصطلحات موضوعية: Polycythaemia, Dihydrofolate reductase activity, Lymphocyte Activation, hemic and lymphatic diseases, Precursor cell, Dihydrofolate reductase, medicine, Humans, Lymphocytes, Polycythemia Vera, Mitosis, Phytohaemagglutinin, Leukemia, biology, Hematology, medicine.disease, Hematologic Diseases, Hodgkin Disease, Enzyme assay, Leukemia, Lymphoid, Leukemia, Myeloid, Acute, Tetrahydrofolate Dehydrogenase, Methotrexate, Cancer research, biology.protein, Multiple Myeloma, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd696de528455aeb5565830d406f1518
https://doi.org/10.1111/j.1600-0609.1977.tb02712.x

المؤلفون: Isabella Scionti, Francesca Michelacci, Marilù Fanelli, Massimo Serra, Katia Scotlandi, Giuseppina Stoico, Piero Picci, Michela Pasello, Daniel Remondini, Claudia Maria Hattinger, Gastone Castellani

المساهمون: Hattinger CM, Stoico G, Michelacci F, Pasello M, Scionti I, Remondini D, Castellani GC, Fanelli M, Scotlandi K, Picci P, Serra M.

المصدر: Genes, Chromosomes and Cancer. 48:289-309

مصطلحات موضوعية: Cancer Research, ATP Binding Cassette Transporter, Subfamily B, Gene Dosage, Genes, myc, Antineoplastic Agents, Biology, Polymerase Chain Reaction, Gene dosage, Malignant transformation, Cell Line, Tumor, Gene duplication, Gene expression, Genetics, Humans, ATP Binding Cassette Transporter, Subfamily B, Member 1, Copy-number variation, Gene, In Situ Hybridization, Fluorescence, Oligonucleotide Array Sequence Analysis, Regulation of gene expression, Comparative Genomic Hybridization, Osteosarcoma, Gene Amplification, Reproducibility of Results, Histone-Lysine N-Methyltransferase, Molecular biology, Gene Expression Regulation, Neoplastic, Tetrahydrofolate Dehydrogenase, Methotrexate, Doxorubicin, Drug Resistance, Neoplasm, Myeloid-Lymphoid Leukemia Protein, Genes, Neoplasm, Comparative genomic hybridization

وصف الملف: STAMPA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86365d2ec227e49e762f848c0ba5618
https://doi.org/10.1002/gcc.20640

المؤلفون: Feng Chen, Jing Bai, Yang Yu, Yuan-xi Feng, Songbin Fu, Wenjing Sun, Chunyu Zhang

المصدر: Basic Toxicology. 99:141-145

مصطلحات موضوعية: medicine.drug_class, Blotting, Western, Cell Cycle Proteins, Ataxia Telangiectasia Mutated Proteins, Drug resistance, Protein Serine-Threonine Kinases, Biology, Pharmacology, Toxicology, Autoantigens, Antimetabolite, Mice, Western blot, medicine, Animals, Oligonucleotide Array Sequence Analysis, Regulation of gene expression, medicine.diagnostic_test, Gene Expression Profiling, Tumor Suppressor Proteins, General Medicine, In vitro, DNA-Binding Proteins, Tetrahydrofolate Dehydrogenase, Methotrexate, Mechanism of action, Drug Resistance, Neoplasm, Cell culture, Cytogenetic Analysis, NIH 3T3 Cells, Cancer research, Multidrug Resistance-Associated Proteins, Tumor Suppressor Protein p53, medicine.symptom, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e6451e8b8d594e65ffd11eb19dc494
https://doi.org/10.1111/j.1742-7843.2006.pto_470.x

المؤلفون: Michael D. Milsom, Leslie J. Fairbairn

المصدر: The Journal of Gene Medicine. 6:133-146

مصطلحات موضوعية: DNA Repair, Hematopoietic System, Genetic enhancement, Drug Resistance, Gene transfer, Biology, In vivo, Drug Discovery, Genetics, medicine, Selective advantage, Animals, Humans, DNA Modification Methylases, Molecular Biology, Transcription factor, Genetics (clinical), Homeodomain Proteins, Hematopoietic stem cell, Genetic Therapy, Tetrahydrofolate Dehydrogenase, Haematopoiesis, medicine.anatomical_structure, Cancer research, Molecular Medicine, ATP-Binding Cassette Transporters, Stem cell, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::838f8ea6c32c21a65f423ea6f998e8e5
https://doi.org/10.1002/jgm.533

المؤلفون: Hiroyuki Kobayashi, Yuzuru Takemura, Satomi Asai, Yasuhiko Ando, Hayato Miyachi

المصدر: Cancer Science. 94:210-214

مصطلحات موضوعية: Intracellular Fluid, musculoskeletal diseases, Antimetabolites, Antineoplastic, Cancer Research, Leukemia, T-Cell, medicine.drug_class, DNA Mutational Analysis, Leucovorin, Mutation, Missense, RFC1, Thymidylate synthase, Antimetabolite, Inhibitory Concentration 50, chemistry.chemical_compound, Dihydrofolate reductase, Tumor Cells, Cultured, medicine, Humans, Point Mutation, Northern blot, Selection, Genetic, Codon, Sequence Deletion, Dose-Response Relationship, Drug, biology, Cell growth, Membrane Proteins, Membrane Transport Proteins, Biological Transport, General Medicine, Molecular biology, Drug Resistance, Multiple, Neoplasm Proteins, Tetrahydrofolate Dehydrogenase, Methotrexate, Amino Acid Substitution, Oncology, Biochemistry, chemistry, Drug Resistance, Neoplasm, Cell culture, Antifolate, Trimetrexate, biology.protein, Fluorouracil, Carrier Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d3d0212073f6afb71bb07ae12219f3c
https://doi.org/10.1111/j.1349-7006.2003.tb01421.x

المؤلفون: Z. Chen, D. G. Priest, M. Bunni, J. L. DiCapua, Peter W. Melera, Wei-Yong Zhu, J. M. Dressler

المصدر: Journal of Experimental Therapeutics and Oncology. 2:264-277

مصطلحات موضوعية: Folate Receptor Alpha, Cancer Research, Drug Resistance, Leucovorin, Alpha (ethology), Receptors, Cell Surface, Cricetulus, Folic Acid, Downregulation and upregulation, Cricetinae, Drug Discovery, Dihydrofolate reductase, medicine, Animals, Metallothionein, Cells, Cultured, Pharmacology, biology, Folate Receptors, GPI-Anchored, Molecular biology, Up-Regulation, Tetrahydrofolate Dehydrogenase, Methotrexate, Trimetrexate, Folate receptor, biology.protein, Folic Acid Antagonists, Carrier Proteins, Intracellular, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7171d73dae56f4ac40283351b6995f3
https://doi.org/10.1046/j.1359-4117.2002.01049.x

المؤلفون: Izumi Hirahara, Yuzuru Takemura, Lin Ma, Yasuhiko Ando, Hiroshi Sonehara, Hiroyuki Kobayashi, Hayato Miyachi

المصدر: International Journal of Cancer. 82:63-69

مصطلحات موضوعية: Antimetabolites, Antineoplastic, Cancer Research, Biology, Somatic evolution in cancer, chemistry.chemical_compound, Acute lymphocytic leukemia, Gene expression, Tumor Cells, Cultured, medicine, Humans, ATP Binding Cassette Transporter, Subfamily B, Member 1, RNA, Messenger, Gene, Cloning, Leukemia, medicine.disease, Molecular biology, Tetrahydrofolate Dehydrogenase, Oncology, chemistry, Drug Resistance, Neoplasm, Trimetrexate, Thymidine, Clone (B-cell biology), Microsatellite Repeats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1d9d5f5c96e285082402e64c5ff23a
https://doi.org/10.1002/(sici)1097-0215(19990702)82:1<63::aid-ijc12>3.0.co;2-2

المؤلفون: Cristina Alemany, Mercè Rodríguez, Valentina Bemi, Angela Miralles, Carlos J. Ciudad, Véronique Noé, Isabel Caragol

المصدر: International Journal of Cancer. 81:785-792

مصطلحات موضوعية: Cancer Research, Drug Evaluation, Preclinical, CHO Cells, Biology, Sensitivity and Specificity, Fatty Acids, Monounsaturated, Cricetinae, Dihydrofolate reductase, Tumor Cells, Cultured, Animals, Humans, Cationic liposome, RNA, Messenger, Fluorescent Dyes, Drug Carriers, Messenger RNA, Phosphorothioate Oligonucleotides, Oligonucleotide, Chinese hamster ovary cell, Intron, RNA, Oligonucleotides, Antisense, Molecular biology, Quaternary Ammonium Compounds, Tetrahydrofolate Dehydrogenase, Oncology, Biochemistry, Liposomes, biology.protein, Cell Division

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94fb783a4273760560c4d79ee333c0c1
https://doi.org/10.1002/(sici)1097-0215(19990531)81:5<785::aid-ijc20>3.0.co;2-8

المؤلفون: Björn Stenkvist, Sigrid Lönn, Ulf Lönn, Bo Nilsson

المصدر: Cancer. 77:107-112

مصطلحات موضوعية: Adult, Cancer Research, medicine.drug_class, medicine.medical_treatment, Breast Neoplasms, Polymerase Chain Reaction, Thymidylate synthase, Antimetabolite, chemistry.chemical_compound, Breast cancer, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Cyclophosphamide, Chemotherapy, biology, business.industry, Gene Amplification, Cancer, Thymidylate Synthase, Middle Aged, medicine.disease, Combined Modality Therapy, Tamoxifen, Tetrahydrofolate Dehydrogenase, Methotrexate, Oncology, chemistry, Chemotherapy, Adjuvant, Fluorouracil, Antifolate, Immunology, Cancer research, biology.protein, Female, Neoplasm Recurrence, Local, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ffc9006931ae9fccd56ea748819a03c
https://doi.org/10.1002/(sici)1097-0142(19960101)77:1<107::aid-cncr18>3.0.co;2-9