المؤلفون: Zhang Z; Cardiovascular Research Center, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China., Xie X; Cardiovascular Research Center, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China., Yao Q; Cardiovascular Research Center, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China., Liu J; Cardiovascular Research Center, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China., Tian Y; Cardiovascular Research Center, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China., Yang C; Cardiovascular Research Center, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China., Xiao L; Cardiovascular Research Center, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China., Wang N; The Advanced Institute for Medical Sciences, Dalian Medical University, Dalian, China.

المصدر: British journal of pharmacology [Br J Pharmacol] 2019 Aug; Vol. 176 (16), pp. 2945-2961. Date of Electronic Publication: 2019 Jul 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Biopterins/*analogs & derivatives , PPAR delta/*physiology , Tetrahydrofolate Dehydrogenase/*physiology, Animals ; Aorta/drug effects ; Aorta/physiology ; Biopterins/physiology ; Cells, Cultured ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/physiology ; Gene Expression/drug effects ; Human Umbilical Vein Endothelial Cells/drug effects ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; PPAR delta/agonists ; PPAR delta/antagonists & inhibitors ; PPAR delta/genetics ; Sulfones/pharmacology ; Tetrahydrofolate Dehydrogenase/genetics ; Thiazoles/pharmacology ; Thiophenes/pharmacology ; Thoracic Arteries/drug effects ; Thoracic Arteries/physiology

المؤلفون: Tonddast-Navaei S; Center for the Study of Systems Biology, School of Biology, Georgia Institute of Technology, 950 Atlantic Drive, Atlanta, Georgia, 30332., Srinivasan B; Center for the Study of Systems Biology, School of Biology, Georgia Institute of Technology, 950 Atlantic Drive, Atlanta, Georgia, 30332., Skolnick J; Center for the Study of Systems Biology, School of Biology, Georgia Institute of Technology, 950 Atlantic Drive, Atlanta, Georgia, 30332.

المصدر: Journal of computational chemistry [J Comput Chem] 2017 Jun 05; Vol. 38 (15), pp. 1252-1259. Date of Electronic Publication: 2016 Nov 16.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 9878362 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-987X (Electronic) Linking ISSN: 01928651 NLM ISO Abbreviation: J Comput Chem Subsets: MEDLINE

مواضيع طبية MeSH: Escherichia coli/*enzymology , Folic Acid Antagonists/*pharmacology , Proteins/*metabolism , Small Molecule Libraries/*pharmacology , Tetrahydrofolate Dehydrogenase/*metabolism, Binding Sites ; Drug Discovery ; Escherichia coli/drug effects ; Escherichia coli Infections/drug therapy ; Folic Acid Antagonists/chemistry ; Humans ; Ligands ; Molecular Docking Simulation ; Protein Binding ; Protein Conformation ; Proteins/chemistry ; Small Molecule Libraries/chemistry ; Tetrahydrofolate Dehydrogenase/chemistry

المؤلفون: Li B; Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen, China., Li Y; Shenzhen Polytechnic, Shenzhen, China., Xu S; Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen, China., Chen H; Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen, China., Dai S; Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen, China., Peng X; Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen, China., Wang L; Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen, China., Liang Y; Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen, China., Li C; Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen, China., Tang B; Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen, China., Zhu L; Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen, China., Zhang T; Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen, China., Lv C; Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen, China., Wang C; Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen, China., Han L; Hwa Mei Hospital, University of Chinese Academy of Sciences, Ningbo, China.; Ningbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Ningbo, China.

المصدر: Journal of clinical laboratory analysis [J Clin Lab Anal] 2021 Mar; Vol. 35 (3), pp. e23689. Date of Electronic Publication: 2020 Dec 31.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 8801384 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-2825 (Electronic) Linking ISSN: 08878013 NLM ISO Abbreviation: J Clin Lab Anal Subsets: MEDLINE

مواضيع طبية MeSH: DNA Methylation*, Homocysteine/*metabolism , Hypertension/*genetics , Ischemic Stroke/*genetics, Adenosylhomocysteinase/genetics ; Adenosylhomocysteinase/metabolism ; Aged ; Asian People/genetics ; Case-Control Studies ; Cross-Sectional Studies ; Cystathionine beta-Synthase/genetics ; Cystathionine beta-Synthase/metabolism ; Female ; Glycine Hydroxymethyltransferase/genetics ; Glycine Hydroxymethyltransferase/metabolism ; Homocysteine/genetics ; Humans ; Hypertension/complications ; Ischemic Stroke/metabolism ; Male ; Methylenetetrahydrofolate Dehydrogenase (NADP)/genetics ; Methylenetetrahydrofolate Dehydrogenase (NADP)/metabolism ; Middle Aged ; Minor Histocompatibility Antigens/genetics ; Minor Histocompatibility Antigens/metabolism ; Tetrahydrofolate Dehydrogenase/genetics ; Tetrahydrofolate Dehydrogenase/metabolism

المؤلفون: Hu J; Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, China., Zhu H; Gynecology & Obstetrics Department, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China., Xu G; Medical Record Statistics Room, Ningbo Medical Center Lihuili Hospital, Ningbo, China., Chen Z; HwaMei Hospital, University of Chinese Academy of Sciences, Ningbo, China., Li L; Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, China., Wang S; Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, China., Deng H; Department of Otorhinolaryngology Head and Neck Surgery, Ningbo Medical Center Lihuili Hospital, Ningbo, China., Bao X; HwaMei Hospital, University of Chinese Academy of Sciences, Ningbo, China.; Ningbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Ningbo, China., Shen Z; Department of Otorhinolaryngology Head and Neck Surgery, Ningbo Medical Center Lihuili Hospital, Ningbo, China.

المصدر: Journal of clinical laboratory analysis [J Clin Lab Anal] 2020 Aug; Vol. 34 (8), pp. e23322. Date of Electronic Publication: 2020 Apr 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 8801384 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-2825 (Electronic) Linking ISSN: 08878013 NLM ISO Abbreviation: J Clin Lab Anal Subsets: MEDLINE

مواضيع طبية MeSH: Hypertension*/complications , Hypertension*/epidemiology , Ischemic Stroke*/complications , Ischemic Stroke*/epidemiology , Ischemic Stroke*/genetics, DNA Methylation/*genetics , Promoter Regions, Genetic/*genetics , Tetrahydrofolate Dehydrogenase/*genetics, Aged ; Case-Control Studies ; China ; Female ; Homocysteine ; Humans ; Male ; Middle Aged ; ROC Curve

المؤلفون: Zheng S; Department of Chemical Engineering, University of Virginia, Charlottesville, VA 22904-4741, USA., Kwon I

المصدر: Biotechnology and bioengineering [Biotechnol Bioeng] 2013 Sep; Vol. 110 (9), pp. 2361-70. Date of Electronic Publication: 2013 Apr 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 7502021 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0290 (Electronic) Linking ISSN: 00063592 NLM ISO Abbreviation: Biotechnol Bioeng Subsets: MEDLINE

مواضيع طبية MeSH: Alanine/*analogs & derivatives , Phenylalanine/*analogs & derivatives , Protein Engineering/*methods , Recombinant Proteins/*genetics , Tetrahydrofolate Dehydrogenase/*genetics, Alanine/chemistry ; Alanine/genetics ; Alanine/metabolism ; Amino Acid Sequence ; Amino Acid Substitution/genetics ; Animals ; Computer Simulation ; Escherichia coli/genetics ; Folic Acid/analogs & derivatives ; Folic Acid/metabolism ; Folic Acid Antagonists ; Methotrexate ; Mice ; Models, Molecular ; Molecular Sequence Data ; Naphthalenes/chemistry ; Naphthalenes/metabolism ; Phenylalanine/chemistry ; Phenylalanine/genetics ; Phenylalanine/metabolism ; Protein Binding/genetics ; Recombinant Proteins/chemistry ; Recombinant Proteins/metabolism ; Sequence Alignment ; Tetrahydrofolate Dehydrogenase/chemistry ; Tetrahydrofolate Dehydrogenase/metabolism ; Tryptophan

المؤلفون: Ottesen JJ; Laboratory of Synthetic Protein Chemistry, The Rockefeller University, New York, NY 10021, USA., Bar-Dagan M, Giovani B, Muir TW

المصدر: Biopolymers [Biopolymers] 2008; Vol. 90 (3), pp. 406-14.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 0372525 Publication Model: Print Cited Medium: Print ISSN: 0006-3525 (Print) Linking ISSN: 00063525 NLM ISO Abbreviation: Biopolymers Subsets: MEDLINE

مواضيع طبية MeSH: Peptide Biosynthesis*, Proto-Oncogene Proteins c-crk/*chemical synthesis , Proto-Oncogene Proteins c-crk/*chemistry , Ribosomes/*chemistry , Tetrahydrofolate Dehydrogenase/*chemical synthesis, Amino Acid Sequence ; Binding Sites ; Carbon Isotopes/metabolism ; Chromatography, High Pressure Liquid ; Cloning, Molecular ; Cysteine/chemistry ; Escherichia coli/genetics ; Models, Chemical ; Nitrogen Isotopes/metabolism ; Nuclear Magnetic Resonance, Biomolecular ; Protein Engineering/methods ; Protein Structure, Tertiary ; Proto-Oncogene Proteins c-crk/genetics ; Proto-Oncogene Proteins c-crk/metabolism ; Recombinant Proteins/chemical synthesis ; Recombinant Proteins/chemistry ; Recombinant Proteins/metabolism ; Tetrahydrofolate Dehydrogenase/chemistry ; Tetrahydrofolate Dehydrogenase/genetics ; Tetrahydrofolate Dehydrogenase/metabolism

المؤلفون: Alakent B; Department of Chemical Engineering, Bogazici University, Bebek, Istanbul 34342, Turkey. burak.alakent@boun.edu.tr, Baskan S, Doruker P

المصدر: Journal of computational chemistry [J Comput Chem] 2011 Feb; Vol. 32 (3), pp. 483-96. Date of Electronic Publication: 2010 Aug 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 9878362 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-987X (Electronic) Linking ISSN: 01928651 NLM ISO Abbreviation: J Comput Chem Subsets: MEDLINE

مواضيع طبية MeSH: Escherichia coli/*enzymology , Tetrahydrofolate Dehydrogenase/*metabolism , Triose-Phosphate Isomerase/*metabolism, Ligands ; Molecular Dynamics Simulation ; Principal Component Analysis ; Protein Binding ; Tetrahydrofolate Dehydrogenase/chemistry ; Triose-Phosphate Isomerase/chemistry

المؤلفون: Rastelli G; Dipartimento di Scienze Farmaceutiche, Università di Modena e Reggio Emilia, Via Campi 183, 41100 Modena, Italy. giulio.rastelli@unimore.it, Del Rio A, Degliesposti G, Sgobba M

المصدر: Journal of computational chemistry [J Comput Chem] 2010 Mar; Vol. 31 (4), pp. 797-810.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 9878362 Publication Model: Print Cited Medium: Internet ISSN: 1096-987X (Electronic) Linking ISSN: 01928651 NLM ISO Abbreviation: J Comput Chem Subsets: MEDLINE

مواضيع طبية MeSH: Models, Chemical* , Molecular Dynamics Simulation* , Quantum Theory*, Enzyme Inhibitors/*chemistry , Tetrahydrofolate Dehydrogenase/*chemistry, Binding Sites ; Enzyme Inhibitors/pharmacology ; High-Throughput Screening Assays ; Ligands ; Models, Molecular ; Molecular Structure ; Plasmodium falciparum/enzymology ; Tetrahydrofolate Dehydrogenase/metabolism ; Water/chemistry

المؤلفون: Murata K; Department of Theoretical Drug Design, Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto, 606-8501 Japan. murata@pharm.kyoto-u.ac.jp, Nagata N, Nakanishi I, Kitaura K

المصدر: Journal of computational chemistry [J Comput Chem] 2010 Mar; Vol. 31 (4), pp. 791-6.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 9878362 Publication Model: Print Cited Medium: Internet ISSN: 1096-987X (Electronic) Linking ISSN: 01928651 NLM ISO Abbreviation: J Comput Chem Subsets: MEDLINE

مواضيع طبية MeSH: Enzyme Inhibitors/*chemistry , Tacrolimus Binding Proteins/*chemistry , Tetrahydrofolate Dehydrogenase/*chemistry, Binding Sites ; Computer Simulation ; Enzyme Inhibitors/pharmacology ; Ligands ; Models, Molecular ; Molecular Conformation ; Quantitative Structure-Activity Relationship ; Solvents/chemistry ; Tacrolimus Binding Proteins/antagonists & inhibitors ; Tacrolimus Binding Proteins/metabolism ; Tetrahydrofolate Dehydrogenase/metabolism

المؤلفون: Boroujerdi AF; Department of Chemistry, Mississippi State University, MS 39762, USA., Young JK

المصدر: Biopolymers [Biopolymers] 2009 Feb; Vol. 91 (2), pp. 140-4.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 0372525 Publication Model: Print Cited Medium: Print ISSN: 0006-3525 (Print) Linking ISSN: 00063525 NLM ISO Abbreviation: Biopolymers Subsets: MEDLINE

مواضيع طبية MeSH: Archaeal Proteins/*chemistry , Folic Acid/*chemistry , Haloferax volcanii/*enzymology , Tetrahydrofolate Dehydrogenase/*chemistry, Archaeal Proteins/metabolism ; Magnetic Resonance Spectroscopy ; Models, Molecular ; Protein Conformation ; Tetrahydrofolate Dehydrogenase/metabolism ; Thermodynamics