المصدر: Cancer Weekly; 7/11/2023, p94-94, 1p

مصطلحات موضوعية: INTEGRATIVE medicine, BIOACTIVE compounds, SAUSSUREA, CANCER cells, ANTINEOPLASTIC agents

مستخلص: Keywords: Anticancer Agents; Biomarkers; Cancer; Cancer Therapy; Diagnostics and Screening; Drugs and Therapies; Health and Medicine; Oncology; Protective Agents; Risk and Prevention EN Anticancer Agents Biomarkers Cancer Cancer Therapy Diagnostics and Screening Drugs and Therapies Health and Medicine Oncology Protective Agents Risk and Prevention 94 94 1 07/10/23 20230711 NES 230711 2023 JUL 11 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Weekly -- Fresh data on cancer are presented in a new report. Anticancer Agents, Biomarkers, Cancer, Cancer Therapy, Diagnostics and Screening, Drugs and Therapies, Health and Medicine, Oncology, Protective Agents, Risk and Prevention Keywords for this news article include: CSIR - Indian Institute of Integrative Medicine, Jammu, India, Asia, Anticancer Agents, Oncology, Biomarkers, Cancer Therapy, Protective Agents, Drugs and Therapies, Health and Medicine, Risk and Prevention, Diagnostics and Screening. [Extracted from the article]

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المصدر: Drug Week; 3/19/2024, p1384-1384, 1p

مصطلحات موضوعية: ANTINEOPLASTIC agents, CANCER treatment, ORAL medication, INTEGRATIVE medicine, UNIVERSITY hospitals

مستخلص: A pilot study conducted at Letterkenny University Hospital in Ireland explored the feasibility of a community-based advanced nurse practitioner-led integrated oncology care model for adults receiving oral anticancer medication (OAMs). The study aimed to assess patient safety, acceptability to patients and staff, and the cost of this new model of care. The results showed that the ANP-led intervention and new model for OAM care were safe, highly acceptable, and cost-effective. Based on the success of the pilot study, the authors recommend further research through a definitive trial. [Extracted from the article]

: Copyright of Drug Week is the property of NewsRx and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المصدر: Drug Week; 2/16/2024, p331-331, 1p

مصطلحات موضوعية: LIVER cancer, ANTINEOPLASTIC agents, TUMORS, T-cell exhaustion, LIFE sciences

مصطلحات جغرافية: FUJIAN Sheng (China)

مستخلص: A study conducted by researchers at Xiamen University in Fujian, China, has found that Pien Tze Huang (PZH) has significant anti-tumor effects in mouse models of melanoma, colorectal cancer, and hepatocellular carcinoma. The study showed that PZH inhibited tumor growth, reduced tumor size, and decreased metastasis in various tumor models. In vitro experiments demonstrated that PZH enhanced T cell activation and cytokine production, while inhibiting T cell exhaustion. The researchers concluded that PZH has potential as a therapeutic agent for cancer treatment. This research has been peer-reviewed and published in the Chinese Journal of Integrative Medicine. [Extracted from the article]

: Copyright of Drug Week is the property of NewsRx and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Saupe, Henning

المصدر: What Doctors Don't Tell You (Nuclear Media); Oct/Nov2023, Issue 26, p48-53, 5p

مصطلحات موضوعية: THERMOTHERAPY, ALTERNATIVE treatment for cancer, CANCER cells, CANCER radiotherapy, CANCER immunotherapy, ANTINEOPLASTIC agents, CANCER patient psychology

مستخلص: The article discusses health information on the use of hyperthermia therapy in the treatment of cancer, adapted from the book "Holistic Cancer Medicine," by Henning Saupe. Topics explored include the impact of hyperthermia on cancer cells during radiation treatment, the possibility of combining hyperthermia with immunotherapy and anticancer medications, and the observed improvement in the mood of cancer patients following hyperthermia therapy.

المصدر: Cancer Weekly; 12/12/2023, p752-752, 1p

مصطلحات موضوعية: GLIOBLASTOMA multiforme, TUMOR growth, BLOOD-brain barrier, ANTINEOPLASTIC agents, BRAIN cancer

مصطلحات جغرافية: HUNAN Sheng (China)

مستخلص: A study conducted at Xiangya Hospital in Hunan, China, has explored the use of carbon dots (CDs) as a potential treatment for glioblastoma, a type of brain cancer. The researchers synthesized a novel type of CDs called MGA-CDs, which demonstrated high permeability through the blood-brain barrier and effective anti-tumor activity. The MGA-CDs were found to target tumor cells' mitochondria, leading to the inhibition of glioblastoma growth. In a mouse model, the MGA-CDs significantly suppressed tumor growth and prolonged the survival of the mice. This research presents a promising strategy for the development of CDs-based therapeutic agents for glioblastoma. [Extracted from the article]

: Copyright of Cancer Weekly is the property of NewsRx and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المصدر: Cancer Weekly; 8/22/2023, p192-192, 1p

مصطلحات موضوعية: ANTINEOPLASTIC agents, CHEMICAL laboratories, NATURAL products, WORKS councils, INDUSTRIAL research, MARINE natural products

المصدر: Oncology Nurse-APN/PA; Feb2020, Vol. 13 Issue 1, p11-13, 3p

مصطلحات موضوعية: ANTINEOPLASTIC agents, COMBINATION drug therapy, IMMUNOTHERAPY, MELANOMA, METASTASIS, MULTIPLE myeloma, GENETIC mutation, PATIENT safety, SURVIVAL, TREATMENT effectiveness, DEXAMETHASONE, DISEASE progression

المؤلفون: Dzoyem, Jean P., NKuete, Antoine H. L., Kuete, Victor, Tala, Michel F., Wabo, Hippolyte K., Guru, Santosh K., Rajput, Vikrant S., Sharma, Akash, Tane, Pierre, Khan, Inshad A., Saxena, Anil K., Laatsch, Hartmut, Ning-Hua Tan

المصدر: Planta Medica; Jul2012, Vol. 78 Issue 8, p787-792, 6p

مصطلحات موضوعية: FOLIAR diagnosis, ANALYSIS of variance, ANTI-infective agents, ANTINEOPLASTIC agents, BACTERIA, CELL culture, CONFIDENCE intervals, HIGH performance liquid chromatography, MOLECULAR structure, PACLITAXEL, PHARMACEUTICAL chemistry, RESEARCH funding, THIN layer chromatography, TOXICITY testing, YEAST, PLANT extracts

مستخلص: The present study was designed to investigate the antimicrobial activity and the cytotoxicity of the methanol extract (PLA) as well as fractions (PLA1-4) and compounds [cardamomin (1), (±)-polygohomoisoflavanone (2), (S)-(-)-pinostrobin (3), 2',4'-dihydroxy-3',6'-dimethoxychalcone (4), (2S)-(-)-5-hydroxy-6,7-dimethoxyflavanone (5), and (2S)-(-)-5,7-dimethoxyflavanone (6)] obtained from leaves of Polygonum limbatum. The microbroth dilution was used to determine the minimal inhibitory concentration (MIC) of the samples against 11 microbial strains including Candida albicans, C. krusei, C. tropicalis, Aspergillus fumigatus, Pseudomonas aeruginosa, Escherichia coli, vancomycin-resistant Enterococcus faecalis (VRE), Staphylococcus aureus, methicillin-resistant S. aureus (MRSA), S.epidermidis, and Mycobacterium tuberculosis H37Rv. The sulphorhodamine B cell growth inhibition assay was used to assess the cytotoxicity of the above samples on lung A549 adenocarcinoma, breast carcinoma MCF-7, prostate carcinoma PC-3, cervical carcinoma HeLa, and the acute monocytic leukemia cell line THP-1. The results of the MIC determination indicated that, apart from fraction PLA3, all other fractions as well as PLA and compound 3 were selectively active. MIC values were noted on 100% of the 11 tested microorganisms for fraction PLA3, 72.7% for PLA, fraction PLA2, and compound 4, 63.6% for PLA1, and 54.5% for fraction PLA4. The results of the cytotoxicity assay revealed that, except for A459 cells, more than 50% inhibition of the proliferation was obtained with each of the tested samples on at least one of the four other cell lines. IC50 values below 4 μg/mL were obtained with 1 and 4 on THP-1 cells. The overall results of the present study provided baseline information for the possible use of Polygonum limbatum as well as some of the isolated compounds for the control of cancer diseases and mostly leukemia. [ABSTRACT FROM AUTHOR]

: Copyright of Planta Medica is the property of Georg Thieme Verlag Stuttgart and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المصدر: Oncology Nurse-APN/PA; Oct2019, Vol. 12 Issue 5, p8-9, 2p

مصطلحات موضوعية: ANTINEOPLASTIC agents, CANCER patients, MULTIPLE myeloma, TREATMENT effectiveness

المؤلفون: Starr, Phoebe

المصدر: Oncology Nurse-APN/PA; Nov2017, Vol. 10 Issue 6, p16-17, 2p

مصطلحات موضوعية: ANTINEOPLASTIC agents, TRANSFERASES, GENETIC mutation, TUMORS, DRUG approval, TREATMENT effectiveness, INVESTIGATIONAL drugs, THERAPEUTICS