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المؤلفون: Burdet, Charles, Nguyen, Thu, Duval, Xavier, Ferreira, Stéphanie, Andremont, Antoine, Guedj, Jérémie, Mentré, France
المساهمون: Infection, Anti-microbiens, Modélisation, Evolution (IAME (UMR_S_1137 / U1137)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Université Sorbonne Paris Cité (USPC), Département d'épidémiologie, biostatistique et recherche clinique, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Genoscreen [Lille, France], The randomized clinical trial was sponsored by Da Volterra (Paris) and funded in part by the European Union Seventh Framework Programme (FP7-HEALTH-2011-single-stage) under grant agreement number 282004, EvoTAR., DAV132-CL-1002 study group, European Project: 282004,EC:FP7:HEALTH,FP7-HEALTH-2011-single-stage,EVOTAR(2011), Comets, Emmanuelle, Evolution and Transfer of Antibiotic Resistance - EVOTAR - - EC:FP7:HEALTH2011-10-01 - 2015-09-30 - 282004 - VALID
المصدر: Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2019, 63 (10), pp.e00820-19. ⟨10.1128/AAC.00820-19⟩مصطلحات موضوعية: metagenomics, [SDV.BIBS] Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], nonlinear mixed effect modelling, dysbiosis, moxifloxacin, human activities, intestinal microbiome, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], diversity
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______1398::ce35eee35c168bd954ba87a27ff95896
https://www.hal.inserm.fr/inserm-02362445 -
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المؤلفون: Burdet, Charles, Nguyen, Thu, Duval, Xavier, Ferreira, Stéphanie, Andremont, Antoine, Guedj, Jérémie, Mentré, France
المساهمون: Infection, Anti-microbiens, Modélisation, Evolution (IAME (UMR_S_1137 / U1137)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Université Sorbonne Paris Cité (USPC), Département d'épidémiologie, biostatistique et recherche clinique, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Genoscreen [Lille, France], The randomized clinical trial was sponsored by Da Volterra (Paris) and funded in part by the European Union Seventh Framework Programme (FP7-HEALTH-2011-single-stage) under grant agreement number 282004, EvoTAR., DAV132-CL-1002 study group, European Project: 282004,EC:FP7:HEALTH,FP7-HEALTH-2011-single-stage,EVOTAR(2011)
المصدر: Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2019, 63 (10), pp.e00820-19. ⟨10.1128/AAC.00820-19⟩مصطلحات موضوعية: metagenomics, nonlinear mixed effect modelling, dysbiosis, moxifloxacin, human activities, intestinal microbiome, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], diversity
URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ce35eee35c168bd954ba87a27ff95896
https://www.hal.inserm.fr/inserm-02362445 -
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المؤلفون: Nguyen, Thi Huyen Tram, Nguyen, Thu Thuy, Mentré, France
المساهمون: Infection, Anti-microbiens, Modélisation, Evolution (IAME (UMR_S_1137 / U1137)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Université Sorbonne Paris Cité (USPC)
المصدر: Pharmaceutical Research
Pharmaceutical Research, 2017, ⟨10.1007/s11095-017-2217-0⟩مصطلحات موضوعية: Optimal design, Bayesian Fisher information matrix, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Data below the limit of quantification, Shrinkage, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], Nonlinear mixed effect models
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المؤلفون: Nguyen, Thi Huyen Tram, Nguyen, Thu Thuy, Mentré, France
المساهمون: Comets, Emmanuelle, Infection, Anti-microbiens, Modélisation, Evolution (IAME (UMR_S_1137 / U1137)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Université Sorbonne Paris Cité (USPC)
المصدر: Pharmaceutical Research
Pharmaceutical Research, 2017, ⟨10.1007/s11095-017-2217-0⟩مصطلحات موضوعية: Optimal design, [SDV.BIBS] Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], [SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie, Bayesian Fisher information matrix, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Data below the limit of quantification, Shrinkage, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], Nonlinear mixed effect models
وصف الملف: application/pdf
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المؤلفون: Madelain, Vincent, Nguyen, Thi Huyen Tram, Olivo, Anaelle, de Lamballerie, Xavier, Guedj, Jérémie, Taburet, Anne-Marie, Mentré, France
المساهمون: Comets, Emmanuelle, Evaluation of the efficacy and of the antiviral activity of T-705 (favipiravir) duringEbola virus infection in non-human primates humans - REACTION - - H20202014-11-01 - 2016-10-31 - 666092 - VALID, Infection, Anti-microbiens, Modélisation, Evolution (IAME (UMR_S_1137 / U1137)), Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Immunologie des Maladies Virales et Autoimmunes (IMVA - U1184), Université Paris-Sud - Paris 11 (UP11)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Hospitalier Universitaire Méditerranée Infection (IHU Marseille), Emergence des Pathologies Virales (EPV), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)-Institut National de la Santé et de la Recherche Médicale (INSERM), European Union’s Horizon 2020 research and innovation programme under grant agreements No. 666092, European Project: 666092,H2020,H2020-Adhoc-2014-20,REACTION(2014), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Université Sorbonne Paris Cité (USPC)
المصدر: Clinical Pharmacokinetics
Clinical Pharmacokinetics, Springer Verlag, 2016, 55 (8), pp.907-23. ⟨10.1007/s40262-015-0364-1⟩
Clinical Pharmacokinetics, 2016, 55 (8), pp.907-23. ⟨10.1007/s40262-015-0364-1⟩مصطلحات موضوعية: 0301 basic medicine, pharmacocinétique, Adenosine, Pyrrolidines, BCX4430, Pharmacology, medicine.disease_cause, Disease Outbreaks, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Pharmacology (medical), media_common, non human primates, [SDV.BIBS] Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], Anticoagulant drug, ZMapp, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences, Ebolavirus, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], Healthy Volunteers, 3. Good health, [SDV.SP] Life Sciences [q-bio]/Pharmaceutical sciences, Pyrazines, Models, Animal, Ebola, [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, medicine.drug, Drug, media_common.quotation_subject, Favipiravir, favipiravir, Antiviral Agents, Article, 03 medical and health sciences, medicine, Animals, Humans, Ebola virus, business.industry, Adenine, Purine Nucleosides, Hemorrhagic Fever, Ebola, Amides, Clinical trial, pharmacodynamique, 030104 developmental biology, Pharmacodynamics, business, Ebola treatment
وصف الملف: application/pdf
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المؤلفون: Panhard, Xavière, Legrand, Mayeule, Taburet, Anne-Marie, Diquet, Bertrand, Goujard, Cécile, Mentré, France, Anrs 102 Study Group, Cophar 1
المساهمون: Modèles et méthodes de l'évaluation thérapeutique des maladies chroniques (U738 / UMR_S738), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Diderot - Paris 7 (UPD7), Département d'épidémiologie, biostatistique et recherche clinique, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de pharmacie, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Bicêtre, Département de Pharmacologie-Toxicologie [CHU Angers], Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM), Service de médecine interne et maladies infectieuses, Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Bicêtre, Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Comets, Emmanuelle
المصدر: European Journal of Clinical Pharmacology
European Journal of Clinical Pharmacology, Springer Verlag, 2007, 63 (11), pp.1019-29. ⟨10.1007/s00228-007-0337-x⟩مصطلحات موضوعية: Male, MESH: Drug Interactions, HIV Infections, Indinavir, Pharmacology, 030226 pharmacology & pharmacy, MESH: Antiretroviral Therapy, Highly Active, 0302 clinical medicine, Antiretroviral Therapy, Highly Active, Drug Interactions, Tissue Distribution, Pharmacology (medical), Population pharmacokinetics, MESH: Anti-HIV Agents, [INFO.INFO-BI] Computer Science [cs]/Bioinformatics [q-bio.QM], MESH: Aged, Volume of distribution, 0303 health sciences, education.field_of_study, [SDV.BIBS] Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], Nelfinavir, MESH: Middle Aged, Stavudine, MESH: Zidovudine, Lamivudine, MESH: HIV Infections, General Medicine, Middle Aged, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], 3. Good health, Reverse Transcriptase Inhibitors, Nucleoside analogs, Female, Zidovudine, MESH: Lamivudine, medicine.drug, Adult, Anti-HIV Agents, MESH: Nelfinavir, Population, MESH: Stavudine, Biology, Models, Biological, Article, 03 medical and health sciences, Pharmacokinetics, medicine, Humans, Drug-drug interactions, MESH: Tissue Distribution, education, Aged, MESH: Humans, 030306 microbiology, MESH: Indinavir, MESH: Models, Biological, MESH: Adult, MESH: Male, MESH: Reverse Transcriptase Inhibitors, [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM], MESH: Female
وصف الملف: application/pdf
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المؤلفون: Nguyen, Thi Huyen Tram, Mentré, France, Levi, Micha, Yu, Jing, Guedj, Jérémie
المساهمون: Infection, Anti-microbiens, Modélisation, Evolution (IAME (UMR_S_1137 / U1137)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Université Sorbonne Paris Cité (USPC), Novartis Pharmaceutical Corporation, Novartis Institutes for BioMedical Research (NIBR), Comets, Emmanuelle
المصدر: Clinical Pharmacology and Therapeutics
Clinical Pharmacology and Therapeutics, American Society for Clinical Pharmacology and Therapeutics, 2014, 96 (5), pp.599-608. ⟨10.1038/clpt.2014.173⟩مصطلحات موضوعية: [SDV.BIBS] Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], FOS: Biological sciences, Quantitative Biology - Quantitative Methods, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], Quantitative Methods (q-bio.QM)
وصف الملف: application/pdf
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المؤلفون: Nyberg, Joakim, Bazzoli, Caroline, Ogungbenro, Kay, Aliev, Alexander, Leonov, Sergei, Duffull, Stephen, Hooker, Andrew, Mentré, France
المساهمون: Comets, Emmanuelle, Department of Pharmaceutical Biosciences, Uppsala University, Laboratoire Jean Kuntzmann (LJK), Université Pierre Mendès France - Grenoble 2 (UPMF)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS), Centre for Applied Pharmacokinetic Research, University of Manchester [Manchester], Institute for Systems Analysis, Russian Academy of Sciences [Moscow] (RAS), AstraZeneca, School of Pharmacy, University of Otago [Dunedin, Nouvelle-Zélande], Modèles et méthodes de l'évaluation thérapeutique des maladies chroniques (U738 / UMR_S738), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM)
المصدر: British Journal of Clinical Pharmacology
British Journal of Clinical Pharmacology, 2015, 79 (1), pp.6-17. ⟨10.1111/bcp.12352⟩مصطلحات موضوعية: PopDes, [SDV.BIBS] Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], population PKPD, PkSaMp, nonlinear mixed effect models, PFIM, Fisher information matrix, population design, POPT, optimal design, POpED, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM]
وصف الملف: application/pdf
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المؤلفون: Nyberg, Joakim, Bazzoli, Caroline, Ogungbenro, Kay, Aliev, Alexander, Leonov, Sergei, Duffull, Stephen, Hooker, Andrew, Mentré, France
المساهمون: Department of Pharmaceutical Biosciences, Uppsala University, Laboratoire Jean Kuntzmann (LJK), Centre National de la Recherche Scientifique (CNRS)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Université Joseph Fourier - Grenoble 1 (UJF)-Université Pierre Mendès France - Grenoble 2 (UPMF), Centre for Applied Pharmacokinetic Research, University of Manchester [Manchester], Institute for Systems Analysis, Russian Academy of Sciences [Moscow] (RAS), AstraZeneca, School of Pharmacy, University of Otago [Dunedin, Nouvelle-Zélande], Modèles et méthodes de l'évaluation thérapeutique des maladies chroniques (U738 / UMR_S738), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Diderot - Paris 7 (UPD7)
المصدر: British Journal of Clinical Pharmacology
British Journal of Clinical Pharmacology, Wiley, 2015, 79 (1), pp.6-17. ⟨10.1111/bcp.12352⟩مصطلحات موضوعية: PopDes, PkSaMp, population PKPD, PFIM, nonlinear mixed effect models, Fisher information matrix, population design, optimal design, POPT, POpED, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM]
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المؤلفون: Couffignal, Camille, Pajot, Olivier, Laouénan, Cédric, Burdet, Charles, Foucrier, Arnaud, Wolff, Michel, Armand-Lefevre, Laurence, Mentré, France, Massias, Laurent
المساهمون: Service de Biostatistique [Bichat], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Infection, Anti-microbiens, Modélisation, Evolution (IAME (UMR_S_1137 / U1137)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Université Sorbonne Paris Cité (USPC), Unité de soins intensifs [Dupouy], Centre Hospitalier Victor Dupouy, Reanimation Médicale et Infectieuse [Bichat], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Bichat-Claude Bernard, Service de Bactériologie [Bichat], Laboratoire de Toxicologie et Pharmacocinétique [Bichat], This study was funded by the Contrat d'Initiation à la Recherche Clinique 2006 (Assistance Publique- Hôpitaux de Paris, Département de la Recherche Clinique et du Développement, CRC 06049), Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Couffignal, Camille, Département d'épidémiologie, biostatistique et recherche clinique, Unité de Soins Intensifs et de Maladies Infectieuses, Pharmacie, This study was funded by the Contrat d’Initiation à la Recherche Clinique 2006 (Assistance Publique-Hôpitaux de Paris, Département de la Recherche Clinique et du Développement, CRC 06049)
المصدر: British Journal of Clinical Pharmacology
British Journal of Clinical Pharmacology, Wiley, 2014, 78 (5), pp.1022-34. ⟨10.1111/bcp.12435⟩مصطلحات موضوعية: Adult, Male, Critical Illness, MESH: Pneumonia, Ventilator-Associated, MESH: Monte Carlo Method, Models, Biological, MESH: Dose-Response Relationship, Drug, MESH: Aged, 80 and over, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, MESH: Anti-Bacterial Agents, MESH: Gram-Negative Bacteria, Gram-Negative Bacteria, Humans, Ventilator-associated pneumonia, Pharmacokinetics, Prospective Studies, Population pharmacokinetics, MESH: Infusions, Intravenous, Infusions, Intravenous, Aged, MESH: Aged, MESH: Imipenem, Aged, 80 and over, MESH: Middle Aged, MESH: Humans, Models, Statistical, Dose-Response Relationship, Drug, MESH: Models, Biological, Pneumonia, Ventilator-Associated, MESH: Adult, Middle Aged, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], MESH: Male, MESH: Prospective Studies, Anti-Bacterial Agents, critical care, [SDV.SP] Life Sciences [q-bio]/Pharmaceutical sciences, criticalcare, Imipenem, MESH: Critical Illness, Female, MESH: Female, Monte Carlo Method, MESH: Models, Statistical
وصف الملف: application/pdf
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