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المؤلفون: Jennifer C. Obike, Mitchell P. Croatt, Cedric J. Pearce, Nicholas H. Oberlies, Huzefa A. Raja, Zeinab Y. Al Subeh
المصدر: The Journal of Antibiotics
مصطلحات موضوعية: 0301 basic medicine, Molecular Conformation, 01 natural sciences, High-performance liquid chromatography, Article, Lactones, Structure-Activity Relationship, Fungal biology, 03 medical and health sciences, chemistry.chemical_compound, Biosynthesis, Drug Discovery, Organic chemistry, Moiety, Centrifugation, Protein Kinase Inhibitors, Chromatography, High Pressure Liquid, Pharmacology, Strain (chemistry), 010405 organic chemistry, Structure elucidation, Fungi, Stereoisomerism, Resorcinols, MAP Kinase Kinase Kinases, Semisynthesis, Anti-Bacterial Agents, Culture Media, 0104 chemical sciences, 030104 developmental biology, chemistry, Fermentation, Zearalenone, Enone
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المصدر: Planta Medica. 88:855-880
مصطلحات موضوعية: Lichens, Pharmaceutical Science, Gram-Positive Bacteria, Depsides, 01 natural sciences, Antioxidants, Analytical Chemistry, Lactones, 03 medical and health sciences, Stictic acid, chemistry.chemical_compound, Anti-Infective Agents, In vivo, Gram-Negative Bacteria, Drug Discovery, medicine, Animals, Humans, Norstictic acid, Lichen, 030304 developmental biology, Pharmacology, 0303 health sciences, Cytotoxins, Chemistry, Organic Chemistry, Antimicrobial, In vitro, Anti-Bacterial Agents, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Complementary and alternative medicine, Mechanism of action, Biochemistry, Candida spp, Molecular Medicine, medicine.symptom
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4909feb1ec0a38c60517fed4408ac8ab
https://doi.org/10.1055/a-1482-6381 -
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المؤلفون: Mieke Hemiawati Satari, Dikdik Kurnia, Eti Apriyanti
المصدر: Combinatorial Chemistry & High Throughput Screening
مصطلحات موضوعية: Rubiaceae, Lactones, chemistry.chemical_compound, 0302 clinical medicine, Mura, Drug Discovery, Gelatinase, Enzyme Inhibitors, Antibacterial agent, GBAP, chemistry.chemical_classification, 0303 health sciences, biology, Quorum Sensing, Biflavonoid, General Medicine, Anti-Bacterial Agents, Computer Science Applications, Molecular Docking Simulation, Serine protease, Biochemistry, Gelatinases, in silico, 030220 oncology & carcinogenesis, Thermodynamics, Quercetin, Protein Binding, Keyzords: Quorum sensing, In Vitro Techniques, Peptides, Cyclic, Article, Structure-Activity Relationship, M. pendans, 03 medical and health sciences, Bacterial Proteins, Biosynthesis, MurA, Biflavonoids, Humans, Taxifolin, 030304 developmental biology, Alkyl and Aryl Transferases, Organic Chemistry, Quorum sensing, chemistry, Flavonoid, biology.protein, Serine Proteases
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af06da6b52a4dee9ab95bcafb5ba0d0
https://doi.org/10.2174/1386207323666200628111348 -
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المصدر: Applied Microbiology and Biotechnology. 104:7117-7130
مصطلحات موضوعية: Methicillin-Resistant Staphylococcus aureus, Aquatic Organisms, Macrocyclic Compounds, Bacillus amyloliquefaciens, Secondary Metabolism, Microbial Sensitivity Tests, medicine.disease_cause, Applied Microbiology and Biotechnology, Enterococcus faecalis, Microbiology, Lactones, 03 medical and health sciences, chemistry.chemical_compound, Peptide deformylase, Polyketide, Drug Resistance, Multiple, Bacterial, Polyketide synthase, medicine, Computer Simulation, Symbiosis, Actinonin, 030304 developmental biology, 0303 health sciences, Bacteria, biology, 030306 microbiology, Pseudomonas aeruginosa, General Medicine, biology.organism_classification, Anti-Bacterial Agents, Biosynthetic Pathways, Klebsiella pneumoniae, chemistry, Staphylococcus aureus, Multigene Family, Rhodophyta, biology.protein, Biotechnology
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المؤلفون: Renqiong Huang, Xiao Sun, Ran Liu, Fang Fang, Yong Wang, Ziheng An, Tiangang Liu, Aisi Fu, Shuai Fu, Zixin Deng
المصدر: Journal of Industrial Microbiology and Biotechnology. 47:275-285
مصطلحات موضوعية: 0303 health sciences, 030306 microbiology, In silico, Bioengineering, Genomics, Biology, Applied Microbiology and Biotechnology, Anti-Bacterial Agents, Metabolic engineering, Lactones, 03 medical and health sciences, chemistry.chemical_compound, Metabolic Engineering, chemistry, Thioesterase, Biochemistry, Multigene Family, Actinomycetales, Gene cluster, Maduramicin, Overproduction, Gene, 030304 developmental biology, Biotechnology
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المؤلفون: Sibyl F. D. Batey, Barrie Wilkinson, Silke Alt, Govind Chandra, Thomas A. Scott, Patrick Wiencek, Christopher S. Francklyn
المصدر: ACS Chemical Biology. 14:2663-2671
مصطلحات موضوعية: 0301 basic medicine, medicine.drug_class, Antibiotics, Pseudomonas fluorescens, Microbial Sensitivity Tests, Gram-Positive Bacteria, 01 natural sciences, Biochemistry, Lactones, 03 medical and health sciences, chemistry.chemical_compound, Immunity, Gram-Negative Bacteria, Threonine-tRNA Ligase, Obafluorin, medicine, chemistry.chemical_classification, Natural product, biology, 010405 organic chemistry, General Medicine, biology.organism_classification, Enzyme assay, Anti-Bacterial Agents, 0104 chemical sciences, 030104 developmental biology, chemistry, Biological target, biology.protein, Molecular Medicine, Lactone
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المؤلفون: Carolina Schillinger, Domen Pogorevc, Silke C. Wenzel, Rolf Jansen, Rolf Müller, Fabian Panter
المصدر: Metabolic Engineering. 55:201-211
مصطلحات موضوعية: 0106 biological sciences, Myxococcus xanthus, Heterologous, Bioengineering, 01 natural sciences, Applied Microbiology and Biotechnology, Lactones, 03 medical and health sciences, chemistry.chemical_compound, Myxobacteria, 010608 biotechnology, RNA polymerase, Polyketide synthase, Binding site, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, biology, biology.organism_classification, Anti-Bacterial Agents, Filaricides, Enzyme, chemistry, Biochemistry, biology.protein, Heterologous expression, Microorganisms, Genetically-Modified, Biotechnology
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المؤلفون: Craig A. Townsend, Trevor A Zandi
المصدر: Proc Natl Acad Sci U S A
مصطلحات موضوعية: Drug, Carbapenem, medicine.drug_class, media_common.quotation_subject, Antibiotics, Microbial Sensitivity Tests, Pharmacology, 01 natural sciences, Meropenem, 03 medical and health sciences, chemistry.chemical_compound, Lactones, Biosynthesis, Pulmonary tuberculosis, medicine, polycyclic compounds, Potency, 030304 developmental biology, media_common, 0303 health sciences, Multidisciplinary, 010405 organic chemistry, Chemistry, biochemical phenomena, metabolism, and nutrition, Biological Sciences, 0104 chemical sciences, Anti-Bacterial Agents, Peptidyl Transferases, medicine.drug, Cysteine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cafcfc0f685457a28a598e3ea6b677f
https://pubmed.ncbi.nlm.nih.gov/34187885 -
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المؤلفون: Junqi Wang, Hui Ji, Shanxiang Jiang, Xinhao Song, Jingjing Zhang, Dawei Guo, Runan Zuo, Lin Peng, Xiaorong Chen, Xiuge Gao, Chunlei Ji
المصدر: Journal of applied toxicology : JATREFERENCES. 41(12)
مصطلحات موضوعية: Endosome, Vacuole, 010501 environmental sciences, Toxicology, 01 natural sciences, Cell Line, 03 medical and health sciences, symbols.namesake, chemistry.chemical_compound, Lactones, Lysosome, medicine, Animals, Micropinocytosis, Maduramicin, 030304 developmental biology, 0105 earth and related environmental sciences, 0303 health sciences, Chemistry, Endoplasmic reticulum, Golgi apparatus, Cardiotoxicity, Cell biology, Anti-Bacterial Agents, Rats, medicine.anatomical_structure, Cytoplasm, symbols, Signal Transduction
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المؤلفون: Laura Reinhardt, Cristina D. Cruz, Gesa Witt, Päivi Tammela, Siham Benramdane, Heike Brötz-Oesterhelt, Elisa Sassetti, Carlos Moreno-Cinos, Mathias Winterhalter, Jurgen Joossens, Irene G. Salado, Philip Gribbon, Koen Augustyns, Björn Windshügel, Pieter Van der Veken
المساهمون: Division of Pharmaceutical Biosciences, Bioactivity Screening Group, Drug Research Program, Publica
المصدر: Journal of Medicinal Chemistry
Journal of medicinal chemistryمصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, 116 Chemical sciences, POTENT INHIBITORS, medicine.disease_cause, 01 natural sciences, CHYMOTRYPSIN, Drug Discovery, LISTERIA-MONOCYTOGENES, Cytotoxicity, biology, Chemistry, Pharmacology. Therapy, Escherichia coli Proteins, Endopeptidase Clp, Anti-Bacterial Agents, 3. Good health, Molecular Docking Simulation, Biochemistry, 317 Pharmacy, ACID, Molecular Medicine, BETA-LACTONES, Serine Proteinase Inhibitors, Protein subunit, Organophosphonates, Virulence, Inhibitory Concentration 50, Structure-Activity Relationship, 03 medical and health sciences, Escherichia coli, medicine, PLASMINOGEN-ACTIVATOR, Mode of action, STAPHYLOCOCCUS-AUREUS, Serine protease, Binding Sites, ANALOGS, Protease, 010405 organic chemistry, Biphenyl Compounds, biology.organism_classification, Protein Structure, Tertiary, 0104 chemical sciences, SERINE-PROTEASE, 030104 developmental biology, biology.protein, VIRULENCE, Bacteria
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