المؤلفون: Christian Sprenger, Elke Vlemincx, Christian Büchel

المساهمون: Methodology and Applied Biostatistics, AMS - Musculoskeletal Health

المصدر: Vlemincx, E, Sprenger, C & Büchel, C 2021, ' Expectation and dyspnoea : The neurobiological basis of respiratory nocebo effects ', European Respiratory Journal, vol. 58, no. 3, 2003008, pp. 1-14 . https://doi.org/10.1183/13993003.03008-2020
European Respiratory Journal, 58(3):2003008, 1-14. European Respiratory Society

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, medicine.medical_specialty, media_common.quotation_subject, Pain, Audiology, Periaqueductal gray, 03 medical and health sciences, 0302 clinical medicine, SDG 3 - Good Health and Well-being, Perception, Humans, Medicine, Clinical significance, 030212 general & internal medicine, Nocebo Effect, Anterior cingulate cortex, media_common, Motivation, medicine.diagnostic_test, business.industry, Magnetic Resonance Imaging, Dyspnea, medicine.anatomical_structure, 030228 respiratory system, Bronchoconstriction, medicine.symptom, business, Functional magnetic resonance imaging, Insula

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d6d7ceb82cb4c3b866fb474802649a9
http://www.scopus.com/inward/record.url?scp=85106338322&partnerID=8YFLogxK

المؤلفون: Tomáš Paus, Pauline Frère, Christian Büchel, Herve Lemaitre, Michael N. Smolka, Gunter Schumann, Frauke Nees, Sylvane Desrivières, Andreas Heinz, Arun L.W. Bokde, Louise Poustka, Tobias Banaschewski, Stella Guldner, Eric Artiges, Hélène Vulser, Christian Massot, Herta Flor, Rubén Miranda-Marcos, Hugh Garavan, Dimitri Papadopoulos-Orfanos, Pascal Zille, Patricia J. Conrod, Jean-Luc Martinot, Henrik Walter, Erin Burke Quinlan, Stefan Heintz, Robert Whelan, Nora C. Vetter, Penny A. Gowland, Laura S. Daedelow, Christian Trichard, Irina Filippi, André Galinowski, Marie-Laure Paillère-Martinot, Uli Bromberg

المصدر: European Neuropsychopharmacology. 49:11-22

مصطلحات موضوعية: Adult, Adolescent, Substance-Related Disorders, media_common.quotation_subject, Neuroimaging, Grey matter, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Gyrus, Fractional anisotropy, Humans, Medicine, Personality, Pharmacology (medical), Biological Psychiatry, media_common, Pharmacology, business.industry, Addiction, Brain, Magnetic Resonance Imaging, 030227 psychiatry, Alcoholism, Psychiatry and Mental health, medicine.anatomical_structure, Neurology, Polysubstance dependence, Cohort, Neurology (clinical), business, 030217 neurology & neurosurgery, Follow-Up Studies, Clinical psychology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::754d8f0164ff5f5b02ea47a6ff43ee37
https://doi.org/10.1016/j.euroneuro.2021.03.001

المؤلفون: Jana Christina Müller, Lars Schwabe, Franziska Magdalena Kausche, Gundula Zerbes, Lea Kampermann, Christian Büchel, Klaus Wiedemann

المصدر: European Neuropsychopharmacology. 43:71-81

مصطلحات موضوعية: Hydrocortisone, Stimulation, Stimulus (physiology), Generalization, Psychological, Arousal, Norepinephrine, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, medicine, Humans, Pharmacology (medical), Fear conditioning, Biological Psychiatry, Pharmacology, Antagonist, Yohimbine, Fear, 030227 psychiatry, Psychiatry and Mental health, Neurology, Anxiety, Neurology (clinical), medicine.symptom, Psychology, Neuroscience, 030217 neurology & neurosurgery, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326012438152d82f4bc3ce49e358e9a0
https://doi.org/10.1016/j.euroneuro.2020.11.015

المؤلفون: Barbara J. Sahakian, Herta Flor, Qi Zhao, Christian Büchel, Qiang Luo, Gunter Schumann, Juliane H. Fröhner, Tomáš Paus, Sylvane Desrivières, Penny A. Gowland, Frauke Nees, Sabina Millenet, Arun L.W. Bokde, Michael N. Smolka, Andreas Heinz, Jianfeng Feng, Tobias Banaschewski, Dimitri Papadopoulos Orfanos, Marie-Laure Paillère-Martinot, Tianye Jia, Jean-Luc Martinot, Eric Artiges, Fei Li, Robert Whelan, Erin Burke Quinlan, Chun Shen, Vincent Frouin, Hugh Garavan, Luise Poustka, Henrik Walter, Bernd Ittermann

المصدر: American journal of psychiatry
Shen, C, Luo, Q, Jia, T, Zhao, Q, Desrivières, S, Quinlan, E B, Banaschewski, T, Millenet, S, Bokde, A L W, Büchel, C, Flor, H, Frouin, V, Garavan, H, Gowland, P, Heinz, A, Ittermann, B, Martinot, J L, Artiges, E, Paillère-Martinot, M L, Nees, F, Orfanos, D P, Paus, T, Poustka, L, Fröhner, J H, Smolka, M N, Walter, H, Whelan, R, Li, F, Feng, J, Schumann, G & Sahakian, B J 2020, ' Neural Correlates of the Dual-Pathway Model for ADHD in Adolescents ', American Journal of Psychiatry, vol. 177, no. 9, pp. 844-854 . https://doi.org/10.1176/appi.ajp.2020.19020183

مصطلحات موضوعية: Male, Adolescent, Prefrontal Cortex, Neuroimaging, Behavioral Symptoms, Neuropsychological Tests, Risk Assessment, 03 medical and health sciences, Cognition, 0302 clinical medicine, mental disorders, medicine, Humans, Attention deficit hyperactivity disorder, Longitudinal Studies, Gray Matter, Dual pathway, Motivation, Neural correlates of consciousness, Biobehavioral Sciences, Organ Size, medicine.disease, 030227 psychiatry, Neuroanatomical Tract-Tracing Techniques, Psychiatry and Mental health, medicine.anatomical_structure, Attention Deficit Disorder with Hyperactivity, Female, Occipital Lobe, Psychology, Neuroscience, 030217 neurology & neurosurgery, Neuroanatomy

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372d29f880267b2c4b35eb7e6102311d
https://doi.org/10.1176/appi.ajp.2020.19020183

المؤلفون: Alex Ing, Luise Poustka, Erin Burke Quinlan, Frauke Nees, Tianye Jia, Andreas Heinz, Bernd Ittermann, Biondo Francesca, Michael N. Smolka, Sylvane Desrivières, Tobias Banaschewski, Arun L.W. Bokde, Robert Whelan, Henrik Walter, Jianfeng Feng, Gareth J. Barker, Tomáš Paus, Qiang Luo, Jean-Luc Martinot, Uli Bromberg, Marie-Laure Paillère Martinot, Juliane H. Fröhner, Hugh Garavan, Nicole Tay, Penny A. Gowland, Dimitri Papadopoulos Orfanos, Herta Flor, Antoine Grigis, Christian Büchel, Gunter Schumann

المصدر: Nature Human Behaviour

مصطلحات موضوعية: Male, Elementary cognitive task, Adolescent, Social Psychology, Experimental and Cognitive Psychology, Emotional processing, Impulsivity, Developmental psychology, Reward processing, Functional brain, 03 medical and health sciences, Behavioral Neuroscience, Cognition, 0302 clinical medicine, Reward, Neuroimaging, Functional neuroimaging, medicine, Humans, Attention, Child, Reinforcement, 030304 developmental biology, 0303 health sciences, Facial expression, Functional Neuroimaging, Brain, Anticipation, Psychological, medicine.disease, Magnetic Resonance Imaging, Comorbidity, Anticipation, Facial Expression, Impulsive Behavior, Female, Nerve Net, medicine.symptom, Psychology, Reinforcement, Psychology, 030217 neurology & neurosurgery, Cognitive psychology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a23969b4c2017d956609670c6327cdeb
https://doi.org/10.1038/s41562-020-0846-5

المؤلفون: Sabina Millenet, Andreas Heinz, Sylvane Desrivières, Hugh Garavan, Philip A. Spechler, Arun L.W. Bokde, Robert Whelan, Celia Boussebaa, Gunter Schumann, Christian Büchel, Henrik Walter, Evangelos Papanastasiou, Penny A. Gowland, Sukhwinder S. Shergill, Marie-Laure Paillère Martinot, Michael N. Smolka, Tobias Banaschewski, Herta Flor, Antoine Grigis, Juliane H. Fröhner, Bernd Ittermann, Luise Poustka, Frauke Nees, Tomáš Paus, Elias Mouchlianitis, Dimitri Papadopoulos Orfanos, Dan W. Joyce, Erin Burke Quinlan, Philip McGuire, Eric Artiges

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports

مصطلحات موضوعية: Male, Psychosis, Adolescent, Databases, Factual, media_common.quotation_subject, medicine.medical_treatment, Emotions, lcsh:Medicine, Amygdala, behavioral disciplines and activities, Article, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Perception, Human behaviour, medicine, Humans, Young adult, 10. No inequality, Antipsychotic, lcsh:Science, media_common, Cerebral Cortex, Facial expression, Multidisciplinary, lcsh:R, Right insula, Brain, Cognitive neuroscience, Diagnostic markers, medicine.disease, Magnetic Resonance Imaging, 030227 psychiatry, Facial Expression, medicine.anatomical_structure, Psychotic Disorders, nervous system, Female, lcsh:Q, Psychology, Insula, 030217 neurology & neurosurgery, psychological phenomena and processes, Clinical psychology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a953f7300584b45552f956b64bde3026
http://link.springer.com/article/10.1038/s41598-020-62026-7

المؤلفون: Rachel Sjouwerman, Alfons O. Hamm, Christian Büchel, Tina B. Lonsdorf, Manuel Kuhn, Julia Wendt

المصدر: Biological Psychiatry. 87:548-558

مصطلحات موضوعية: 0301 basic medicine, Reflex, Startle, medicine.diagnostic_test, Electromyography, Reproducibility of Results, Fear, Affective neuroscience, Magnetic Resonance Imaging, Amygdala, Fear-potentiated startle, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Moro reflex, medicine, Pupillary response, Humans, Valence (psychology), Functional magnetic resonance imaging, Psychology, Neuroscience, Facial electromyography, 030217 neurology & neurosurgery, Biological Psychiatry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::644a428960425e394180f07946632b93
https://doi.org/10.1016/j.biopsych.2019.07.028

المؤلفون: Markus M. Nöthen, Herta Flor, Ilya M. Veer, Dimitri Papadopoulos-Orfanos, Gunter Schumann, Bernd Ittermann, Nina Romanczuk-Seiferth, Christian Büchel, Erin Burke Quinlan, Susanne Erk, Sylvane Desrivières, Henrik Walter, Marcella Rietschel, Tomáš Paus, Arun L.W. Bokde, Luise Poustka, Marie-Laure Paillère Martinot, Penny A. Gowland, Vassily Trubetskoy, Andreas Meyer-Lindenberg, Bob O. Vogel, Juliane H. Fröhner, Tobias Banaschewski, Vincent Frouin, Jean-Luc Martinot, Eva J. Brandl, Michael N. Smolka, Frauke Nees, Swapnil Awasthi, Tristram A. Lett, Franziska Degenhardt, Stephanie H. Witt, Andreas Heinz, Robert Whelan, Sebastian Mohnke, Hugh Garavan, Stephan Ripke, Carolin Wackerhagen, Heike Tost

المصدر: Cereb Cortex

مصطلحات موضوعية: Male, Oncology, Multifactorial Inheritance, Mediation (statistics), medicine.medical_specialty, Adolescent, Cognitive Neuroscience, Intelligence, Genome-wide association study, Biology, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Neurocognitive Dysfunction, Cortex (anatomy), Internal medicine, medicine, Humans, Longitudinal Studies, 030304 developmental biology, Genetic association, Cerebral Cortex, 0303 health sciences, Explained variation, Genetic load, medicine.anatomical_structure, Original Article, Female, Insula, 030217 neurology & neurosurgery, Genome-Wide Association Study

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edeb0948d4ef9982e37d8e9a9a2c88c9
https://doi.org/10.1093/cercor/bhz270

المؤلفون: Alexandra Tinnermann, Dimitri Van De Ville, Cornelia Laule, Sean Mackey, Robert L. Barry, Benjamin De Leener, Anna Pichiecchio, Eva Alonso-Ortiz, Giancarlo Germani, Ali Khatibi, Nico Papinutto, Marc J. Ruitenberg, René Labounek, Nawal Kinany, Francesco Grussu, Michela Fratini, Petr Kudlička, Christophe Lenglet, Kouhei Kamiya, Pierre-Gilles Henry, Julien Cohen-Adad, Richard G. Wise, Deborah Pareto, Tomáš Horák, Jürgen Finsterbusch, Alex Rovira, Todd B. Parrish, Y. Suzuki, George Tackley, Junqian Xu, Falk Eippert, Virginie Callot, Daniel Papp, Laura Barlow, Karla R. Epperson, Charley Gros, Nicole Atcheson, Akifumi Hagiwara, Jan Valošek, Yaou Liu, Patrick Freund, Maria Marcella Laganà, James M. Joers, Marco Battiston, Markus Barth, Adam V. Dvorak, Masaaki Hori, Joo Won Kim, Miloš Keřkovský, Paulo Loureiro de Sousa, Sara Llufriu, Mihael Abramovic, Igor Nestrasil, Kenneth A. Weber, Christine S. Law, Paul Kuntke, Elisabeth Solana, Kristin P. O’Grady, Alexandru Foias, Slawomir Kusmia, Claudia A. M. Wheeler-Kingshott, Hagen H. Kitzler, Alex K. Smith, Nyoman D. Kurniawan, Shannon H. Kolind, Marios C. Yiannakas, Seth A. Smith, Zachary A. Smith, Federico Giove, Tobias Leutritz, Matthew D. Budde, Rebecca S. Samson, Christian Büchel, Kevin S. Epperson, Marek Dostál, Giovanni Savini, Issei Fukunaga, Haleh Karbasforoushan, Loan Mattera, Nikolaus Weiskopf, Guillaume Gilbert, Yazhuo Kong, Ferran Prados, Maryam Seif, Anna J.E. Combes, Julien Doyon, P Wyss, Alan C. Seifert, Carina Arneitz, Eloy Martinez-Heras, Maxime Descoteaux

المساهمون: Centre de résonance magnétique biologique et médicale (CRMBM), Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)-Centre National de la Recherche Scientifique (CNRS), Centre d'Exploration Métabolique par Résonance Magnétique [Hôpital de la Timone - AP-HM] (CEMEREM), Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)-Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)-Centre National de la Recherche Scientifique (CNRS)- Hôpital de la Timone [CHU - APHM] (TIMONE), Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie (ICube), École Nationale du Génie de l'Eau et de l'Environnement de Strasbourg (ENGEES)-Université de Strasbourg (UNISTRA)-Institut National des Sciences Appliquées - Strasbourg (INSA Strasbourg), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Matériaux et nanosciences d'Alsace (FMNGE), Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Réseau nanophotonique et optique, Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA), Universitat Oberta de Catalunya (UOC), Universitat Oberta de Catalunya. eHealth Center, Institut Català de la Salut, [Cohen-Adad J] NeuroPoly Lab, Institute of Biomedical Engineering, Polytechnique Montreal, Montreal, QC, Canada. Functional Neuroimaging Unit, CRIUGM, Université de Montréal, Montreal, QC, Canada. Mila - Quebec AI Institute, Montreal, QC, Canada. [Alonso-Ortiz E] NeuroPoly Lab, Institute of Biomedical Engineering, Polytechnique Montreal, Montreal, QC, Canada. [Abramovic M, Arneitz C] Department of Radiology, Swiss Paraplegic Centre, Nottwil, Switzerland. [Atcheson N] Centre for Advanced Imaging, The University of Queensland, Brisbane, Australia. [Barlow L] Department of Radiology, University of British Columbia, Vancouver, BC, Canada. [Grussu F] NMR Research Unit, Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK. Radiomics Group, Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain. Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Pareto D, Rovira À] Secció de Neuroradiologia, Vall d’Hebron Hospital Universitri, Barcelona, Spain, Vall d'Hebron Barcelona Hospital Campus, Centre d'Exploration Métabolique par Résonance Magnétique [Hôpital de la Timone - APHM] (CEMEREM), Hôpital de la Timone [CHU - APHM] (TIMONE)-Centre de résonance magnétique biologique et médicale (CRMBM), Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)-Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)-Centre National de la Recherche Scientifique (CNRS), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de Recherche en Informatique et en Automatique (Inria)-Les Hôpitaux Universitaires de Strasbourg (HUS)-Centre National de la Recherche Scientifique (CNRS)-Matériaux et Nanosciences Grand-Est (MNGE), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Réseau nanophotonique et optique, Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Scientific Data
Scientific Data, Nature Publishing Group, 2021, 8 (1), ⟨10.1038/s41597-021-00941-8⟩
Scientia
Scientific Data, 2021, 8 (1), ⟨10.1038/s41597-021-00941-8⟩
Scientific Data, Vol 8, Iss 1, Pp 1-17 (2021)
O2, repositorio institucional de la UOC
Universitat Oberta de Catalunya (UOC)

مصطلحات موضوعية: Statistics and Probability, Data Descriptor, medicine.medical_specialty, Sciences du Vivant [q-bio]/Neurosciences [q-bio.NC], Investigació - Avaluació, Nervous System::Central Nervous System::Spinal Cord [ANATOMY], databases, Computer science, Science, of-the-art, Spinal cord diseases, Spinal Cord Diseases, Imaging techniques, Library and Information Sciences, 030218 nuclear medicine & medical imaging, Education, Databases, 03 medical and health sciences, 0302 clinical medicine, Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Tomography::Magnetic Resonance Imaging [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT], Investigative Techniques::Epidemiologic Methods::Epidemiologic Research Design::Reproducibility of Results [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT], medicine, Medical physics, diagnóstico::técnicas y procedimientos diagnósticos::diagnóstico por imagen::tomografía::imagen por resonancia magnética [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS], Other subheadings::Other subheadings::/diagnostic imaging [Other subheadings], Protocol (science), Reproducibility, Extramural, Otros calificadores::Otros calificadores::/diagnóstico por imagen [Otros calificadores], técnicas de investigación::métodos epidemiológicos::diseño de la investigación epidemiológica::reproducibilidad de los resultados [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS], white, Spinal cord, spinal cord diseases, Toolbox, imaging techniques, matter, Computer Science Applications, magnetization-transfer, medicine.anatomical_structure, Imatgeria per ressonància magnètica, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], sistema nervioso::sistema nervioso central::médula espinal [ANATOMÍA], Statistics, Probability and Uncertainty, Medul·la espinal - Malalties - Imatgeria, 030217 neurology & neurosurgery, Information Systems

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c5540515bdd8d039cbee3450a1bd07a
https://hal.archives-ouvertes.fr/hal-03402837/file/2021_scientific_data_consensus_repro_cohen-adad.pdf

المؤلفون: Alexandra Tinnermann, Christian Büchel, Jan Haaker

المصدر: Science Advances

مصطلحات موضوعية: Brain activation, 0303 health sciences, Multidisciplinary, business.industry, Cognitive Neuroscience, SciAdv r-articles, Social Sciences, Stimulation, Heat pain, Dorsolateral, Spinal cord, Physiological responses, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Medicine, business, Social information, Neuroscience, Research Articles, 030217 neurology & neurosurgery, Research Article, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3eb4eef2ff6d2150f8f17f124a2f6d9
https://doi.org/10.1126/sciadv.abe8444