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المؤلفون: Demetra Kiltzanidi, Francesco Tartaglia, Giovanni Carbotta, Giovanni Tortorelli, Luciana Tromba, S Carbotta, Stefania Cavaiola, Fabio Pelle, Alessandro Giuliani, Sara Blasi
المصدر: Journal of Women's Health. 25:348-354
مصطلحات موضوعية: Carotid Artery Diseases, Male, Hyperpnea, 030204 cardiovascular system & hematology, 0302 clinical medicine, Risk Factors, 80 and over, Prevalence, Medicine, Carotid Stenosis, Plaque, Atherosclerotic, Aged, 80 and over, Hypertriglyceridemia, Ultrasound, Apnea, General Medicine, Middle Aged, Plaque, Atherosclerotic, Carotid Arteries, Italy, Hypertension, cardiovascular system, epidemiology, Female, Radiology, medicine.symptom, Adult, medicine.medical_specialty, diagnostic imaging, Hypercholesterolemia, 03 medical and health sciences, Age Distribution, Sex Factors, Heart rate, Diabetes Mellitus, Humans, Aged, Carotid Arteries, diagnostic imaging, Carotid Artery Diseases,diagnostic imaging, Carotid Stenosis, diagnostic imaging, Carotid Stenosis, epidemiology, Carotid Stenosis, pathology, Case-Control Studies, Diabetes Mellitus, epidemiology, Hypercholesterolemia, epidemiology, Hypertension, physiopathology, Hypertriglyceridemia, epidemiology, Plaque, Atherosclerotic, epidemiology, Tunica Intima, pathology, pathology, business.industry, Case-control study, Echogenicity, medicine.disease, Stenosis, physiopathology, Tunica Intima, business, 030217 neurology & neurosurgery
الوصف: We set out to study, through ultrasound examinations, the carotid bifurcation in men and women with/without carotid stenosis to look for anatomical and electrophysiologic differences. We evaluated other variables to look for differences that might explain the dissimilar behavior of this disease in the two sexes and the presence and impact of risk factors.We examined 974 subjects aged 25 to 88 years (478 men and 496 women) in whom we considered heart rate, smoking status, and the presence of hypertension, diabetes, hypercholesterolemia, and hypertriglyceridemia. Ultrasound examination of the neck vessels included measurement of intimal medial thickness (IMT), vessel diameter, and outflow area/inflow area ratio. We established plaque location, echogenicity and echostructure, and the percentage of stenosis owing to plaque and measured systolic velocity, flow direction, and the depth of detection of these parameters. We used the apnea and hyperpnea test to assess cerebrovascular reactivity.Hypertension and hypercholesterolemia were the most frequent risk factors. Women had a higher heart rate, whereas men had significantly greater IMT. The presence of atheromatous plaque was significantly correlated with age in both sexes, with men having a higher prevalence of carotid plaques. The sexes differed significantly with regard to plaque location, echogenicity, echostructure, and intracranial circulation. Women had a slightly higher blood flow velocity in the intracranial arteries. Risk factors affected plaque formation and extent more in men than in women.These findings suggest that carotid stenosis is a gender-related trait.
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595fabb18712bc382672b6ec7d70dae6
https://doi.org/10.1089/jwh.2015.5300 -
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المؤلفون: Cédric Gubelmann, Pedro Marques-Vidal, Peter Vollenweider
المصدر: European journal of preventive cardiology, vol. 24, no. 5, pp. 514-521
Europe PubMed Centralمصطلحات موضوعية: Male, Muscle Strength Dynamometer, Homocysteine, Epidemiology, Cross-sectional study, 030204 cardiovascular system & hematology, Severity of Illness Index, Body Mass Index, Grip strength, chemistry.chemical_compound, 0302 clinical medicine, Surveys and Questionnaires, Prevalence, 030212 general & internal medicine, education.field_of_study, Hand Strength, Smoking, Age Factors, Middle Aged, Cardiovascular Diseases, Hypertension, Female, Aged, Biomarkers/analysis, Cardiovascular Diseases/diagnosis, Cardiovascular Diseases/epidemiology, Cross-Sectional Studies, Hand Strength/physiology, Health Surveys, Humans, Hypercholesterolemia/diagnosis, Hypercholesterolemia/epidemiology, Hypertension/epidemiology, Linear Models, Multivariate Analysis, Obesity/diagnosis, Obesity/epidemiology, Risk Assessment, Sex Factors, Smoking/epidemiology, Switzerland/epidemiology, Switzerland, anthropometry, blood pressure, glucose, inflammation, lipids, population-based study, Cardiology and Cardiovascular Medicine, medicine.medical_specialty, Hypercholesterolemia, Population, 03 medical and health sciences, Internal medicine, medicine, Obesity, education, business.industry, Anthropometry, Blood pressure, chemistry, Physical therapy, business, Body mass index, Biomarkers
الوصف: Background Mechanisms underlying the association between grip strength and cardiovascular mortality are poorly understood. We aimed to assess the association of grip strength with a panel of cardiovascular risk markers. Design The study was based on a cross-sectional analysis of 3468 adults aged 50-75 years (1891 women) from a population-based sample in Lausanne, Switzerland. Methods Grip strength was measured using a hydraulic hand dynamometer. Cardiovascular risk markers included anthropometry, blood pressure, lipids, glucose, adiposity, inflammatory and other metabolic markers. Results In both genders, grip strength was negatively associated with fat mass (Pearson correlation coefficient: women: -0.170, men: -0.198), systolic blood pressure (women: -0.096, men: -0.074), fasting glucose (women: -0.048, men: -0.071), log-transformed leptin (women: -0.074, men: -0.065), log-transformed high-sensitivity C-reactive protein (women: -0.101, men: -0.079) and log-transformed homocysteine (women: -0.109, men: -0.060). In men, grip strength was also positively associated with diastolic blood pressure (0.068), total (0.106) and low density lipoprotein-cholesterol (0.082), and negatively associated with interleukin-6 (-0.071); in women, grip strength was negatively associated with triglycerides (-0.064) and uric acid (-0.059). After multivariate adjustment, grip strength was negatively associated with waist circumference (change per 5 kg increase in grip strength: -0.82 cm in women and -0.77 cm in men), fat mass (-0.56% in women; -0.27% in men) and high-sensitivity C-reactive protein (-6.8% in women; -3.2% in men) in both genders, and with body mass index (0.22 kg/m javax.xml.bind.JAXBElement@165be361 ) and leptin (-2.7%) in men. Conclusion Grip strength shows only moderate associations with cardiovascular risk markers. The effect of muscle strength as measured by grip strength on cardiovascular disease does not seem to be mediated by cardiovascular risk markers.
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e980f4b37bf0f9e4c1880e66d5fde70
https://zenodo.org/record/211816 -
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المؤلفون: Eduardo Faerstein, Luís Eduardo Teixeira de Macedo
المصدر: Revista de Saúde Pública, Vol 51, Iss 0
Revista de Saúde Públicaمصطلحات موضوعية: medicine.medical_specialty, Hypercholesterolemia, MEDLINE, Guidelines as Topic, Disease, 030204 cardiovascular system & hematology, Risk Assessment, Dyslipidemias, diagnosis, Atherosclerosis, prevention & control, Cardiovascular Diseases, prevention & control, 03 medical and health sciences, Frontier, 0302 clinical medicine, Reference Values, Risk Factors, Dislipidemias, diagnóstico, medicine, Humans, Hypercholesterolemia, epidemiology, 030212 general & internal medicine, Overdiagnosis, Hipercolesterolemia, epidemiologia, Intensive care medicine, Diagnóstico Precoce, Preventive strategy, business.industry, Aterosclerose, prevenção & controle, Public health, lcsh:Public aspects of medicine, Public Health, Environmental and Occupational Health, lcsh:RA1-1270, Atherosclerosis, medicine.disease, Early Diagnosis, Doenças Cardiovasculares, prevenção & controle, Risk assessment, business, Brazil, Comments, Dyslipidemia
الوصف: Control of atherosclerotic cardiovascular disease - a highly prevalent condition and one of the main causes of mortality in Brazil and worldwide - is a recurrent subject of great interest for public health. Recently, three new guidelines on dyslipidemia and atherosclerosis prevention have been published. The close release of these important publications is a good opportunity for comparison: the Brazilian model has greater sensitivity, the English model does not work with risk stratification, and the American model may be overestimating the risk. This will allow reflection on current progress and identification of controversial aspects which still require further research and debate. It is also an opportunity to discuss issues related to early diagnosis and its efficiency as a preventive strategy for atherosclerotic disease: the transformation of risk into disease, the gradual reduction of cut-off points, the limitations of the screening strategy, and the problem of overdiagnosis. RESUMO O controle da doença cardiovascular aterosclerótica - morbidade de alta prevalência e uma das principais causas de mortalidade no Brasil e no mundo - continua sendo tema de grande interesse para a Saúde Pública. Recentemente, três novas diretrizes sobre dislipidemia e prevenção da aterosclerose foram divulgadas. A convergência no tempo dessas importantes publicações constitui boa oportunidade para sua comparação: o modelo brasileiro tem maior sensibilidade, o inglês não trabalha com risco estratificado e o norte-americano parece estar superestimando o risco.Isso permitirá reflexões acerca dos avanços que já foram alcançados e identificação de aspectos ainda controversos, que seguem exigindo novas pesquisas e debates. É também uma oportunidade para discutir questões relacionadas ao diagnóstico precoce e sua eficiência como estratégia preventiva da doença aterosclerótica: as transformações do risco em doença, a diminuição progressiva de pontos de corte, as insuficiências da estratégia de rastreamento e o problema do sobrediagnóstico.
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b47253044067e5228bb4cafcbac55e3
http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0034-89102017000100601&lng=en&tlng=en -
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المصدر: BMC Public Health, Vol 16, Iss 1, Pp 1-11 (2016)
BMC Public Healthمصطلحات موضوعية: Male, 0301 basic medicine, Cross-sectional study, 0302 clinical medicine, Risk Factors, Epidemiology, Prevalence, 030212 general & internal medicine, education.field_of_study, lcsh:Public aspects of medicine, Age Factors, Cardiovascular disease/epidemiology, Odds ratio, Middle Aged, 3. Good health, Self disclosure, Cholesterol, Cardiovascular Diseases, Hypertension, Income, Hypercholesterolemia/epidemiology, Female, Research Article, Adult, medicine.medical_specialty, Adolescent, Health surveys, Hypercholesterolemia, Population, Young Adult, 03 medical and health sciences, Hypertension/epidemiology, Environmental health, Diabetes mellitus, Diabetes Mellitus, medicine, Humans, Risk factor, education, Aged, business.industry, Public health, Australia, Public Health, Environmental and Occupational Health, lcsh:RA1-1270, medicine.disease, Logistic models, Cross-Sectional Studies, 030104 developmental biology, Blood pressure, Multivariate analysis, Self Report, Diabetes mellitus/epidemiology, business
الوصف: Background Measuring and monitoring the true prevalence of risk factors for chronic conditions is essential for evidence-based policy and health service planning. Understanding the prevalence of risk factors for cardiovascular disease (CVD) in Australia relies heavily on self-report measures from surveys, such as the triennial National Health Survey. However, international evidence suggests that self-reported data may substantially underestimate actual risk factor prevalence. This study sought to characterise the extent of misreporting in a large, nationally-representative health survey that included objective measures of clinical risk factors for CVD. Methods This study employed a cross-sectional analysis of 7269 adults aged 18 years and over who provided fasting blood samples as part of the 2011–12 Australian Health Survey. Self-reported prevalence of high blood pressure, high cholesterol and diabetes was compared to measured prevalence, and univariate and multivariate logistic regression analyses identified socio-demographic characteristics associated with underreporting for each risk factor. Results Approximately 16 % of the total sample underreported high blood pressure (measured to be at high risk but didn’t report a diagnosis), 33 % underreported high cholesterol, and 1.3 % underreported diabetes. Among those measured to be at high risk, 68 % did not report a diagnosis for high blood pressure, nor did 89 % of people with high cholesterol and 29 % of people with high fasting plasma glucose. Younger age was associated with underreporting high blood pressure and high cholesterol, while lower area-level disadvantage and higher income were associated with underreporting diabetes. Conclusions Underreporting has important implications for CVD risk factor surveillance, policy planning and decisions, and clinical best-practice guidelines. This analysis highlights concerns about the reach of primary prevention efforts in certain groups and implications for patients who may be unaware of their disease risk status.
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d41d0f4645efc7cf04a570a65411285
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