المؤلفون: Haojie Huang, Jacob J. Orme

المصدر: Cancer cell

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Neuregulin-1, Anti-Androgen, urologic and male genital diseases, Article, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Castration Resistance, mental disorders, Tumor Microenvironment, medicine, Humans, Neuregulin 1, skin and connective tissue diseases, Receptor, Tumor microenvironment, biology, Extramural, business.industry, Androgen Antagonists, Cell Biology, medicine.disease, body regions, Prostatic Neoplasms, Castration-Resistant, 030104 developmental biology, Oncology, Receptors, Androgen, 030220 oncology & carcinogenesis, Cancer cell, biology.protein, Cancer research, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::487f82ac7d3955fed51972fc63dbd3d3
https://doi.org/10.1016/j.ccell.2020.07.007

المؤلفون: Haojie Huang, Ting Wei, Martin E. Gleave, Ladan Fazli, Lei Shi, Yuzhuo Wang, R. Jeffrey Karnes, Jacob J. Orme, Yundong He, Haoyue Sheng, Zhenqing Ye, Rafael E. Jimenez, Liguo Wang, Liewei Wang, Dong Lin

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications

مصطلحات موضوعية: Male, 0301 basic medicine, General Physics and Astronomy, Angiotensin-Converting Enzyme Inhibitors, Mice, SCID, urologic and male genital diseases, Biochemistry, Mice, chemistry.chemical_compound, Prostate cancer, 0302 clinical medicine, Cancer, Multidisciplinary, Up-Regulation, DNA-Binding Proteins, Organoids, CpG site, Receptors, Androgen, 030220 oncology & carcinogenesis, Benzamides, Signal Transduction, Hepatocyte Nuclear Factor 3-alpha, medicine.drug_class, Science, Article, General Biochemistry, Genetics and Molecular Biology, Angiotensin Receptor Antagonists, 03 medical and health sciences, Nitriles, Phenylthiohydantoin, medicine, Animals, Humans, Enzalutamide, Binding site, Cell Proliferation, Binding Sites, Pioneer factor, Prostatic Neoplasms, Androgen Antagonists, General Chemistry, Androgen, medicine.disease, Xenograft Model Antitumor Assays, Androgen receptor, 030104 developmental biology, chemistry, Cancer research, FOXA1, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28022545df36fab6a142a6da9ae772f9
https://doi.org/10.1038/s41467-021-21860-7

المؤلفون: Yong Du, Chun Xie, Xin J. Zhou, Sneha Ravikumar, Li Li, Chandra Mohan, Jacob J. Orme

المصدر: International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 2059, p 2059 (2021)

مصطلحات موضوعية: 0301 basic medicine, Glomerulonephritis, Membranoproliferative, SMAD, Disease, Kidney, Catalysis, Article, Inorganic Chemistry, lcsh:Chemistry, 03 medical and health sciences, 0302 clinical medicine, Immune system, Transforming Growth Factor beta, medicine, Animals, RNA, Messenger, Smad3 Protein, Physical and Theoretical Chemistry, Molecular Biology, lcsh:QH301-705.5, Spectroscopy, anti-GBM nephritis, 129sv strain, 030203 arthritis & rheumatology, Basement membrane, Crescentic glomerulonephritis, business.industry, Organic Chemistry, General Medicine, medicine.disease, TGF-β/SMAD signaling, Computer Science Applications, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, Gene Expression Regulation, lcsh:Biology (General), lcsh:QD1-999, Cancer research, Phosphorylation, Collagen, business, Nephritis, Signal Transduction, Transforming growth factor

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144075788b168d767e1d5e6983680152
http://europepmc.org/articles/PMC7922100

المؤلفون: Matthew K. Ball, Jose C. Villasboas, Aaron S. Mansfield, Xin Liu, Benjamin J. Madden, Roxana S. Dronca, Bharath Wootla, Jacob J. Orme, M. Cristine Charlesworth, Tiancheng Xie, Yanli Li, Fabrice Lucien, Susan M. Harrington, Haidong Dong, Tariq U. Azam, Khalid Jazieh

المصدر: Oncoimmunology
OncoImmunology, Vol 9, Iss 1 (2020)

مصطلحات موضوعية: 0301 basic medicine, checkpoint inhibitor resistance, Poor prognosis, ADAM10, Immunology, Apoptosis, ADAM17 Protein, B7-H1 Antigen, sPD-L1, 03 medical and health sciences, ADAM10 Protein, 0302 clinical medicine, PD-L1, Cleave, Immunology and Allergy, Humans, In patient, RC254-282, Original Research, ADAM17, biology, Chemistry, Mechanism (biology), Inhibitor resistance, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Membrane Proteins, RC581-607, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, biology.protein, Cancer research, PD-1 resistance, Immunologic diseases. Allergy, Amyloid Precursor Protein Secretases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3830d88090205d3747a536ae3e9a2fc7
http://europepmc.org/articles/PMC7185206

المؤلفون: Nina Staudacher, Manuela Schmidinger, Renate Pichler, Gennadi Tulchiner, Andrea Brunner, Wolfgang Horninger, Zoran Culig, Jacob J. Orme, Martin Thurnher

المصدر: Bju International

مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, Immune checkpoint inhibitors, Urology, medicine.medical_treatment, urologic and male genital diseases, Research Communications, Research Communication, 03 medical and health sciences, 0302 clinical medicine, Renal cell carcinoma, Internal medicine, Biomarkers, Tumor, medicine, Humans, Carcinoma, Renal Cell, Predictive biomarker, MARVEL Domain-Containing Proteins, business.industry, Immunotherapy, medicine.disease, Predictive value, Kidney Neoplasms, 030104 developmental biology, 030220 oncology & carcinogenesis, Potential biomarkers, Cancer research, Immunohistochemistry, Nivolumab, business, Myelin Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f34a48775d4dfedde15b498d19c2508
https://doi.org/10.1016/s0302-2838(21)00926-x

المؤلفون: Di Wu, Dejie Wang, Yunqian Pan, Zhenqing Ye, Yu-Tian Xiao, Haojie Huang, Ting Wei, Shancheng Ren, Liguo Wang, Jacob J. Orme, Yuqian Yan

المصدر: Cell Reports. 34:108744

مصطلحات موضوعية: Male, 0301 basic medicine, BRD4, Nerve Tissue Proteins, Receptors, Cell Surface, Mice, SCID, General Biochemistry, Genetics and Molecular Biology, Histones, Mice, Phosphatidylinositol 3-Kinases, 03 medical and health sciences, Histone H3, 0302 clinical medicine, Cell Line, Tumor, Neoplasms, Animals, Humans, Protein kinase B, PI3K/AKT/mTOR pathway, Cell Proliferation, Phosphoinositide-3 Kinase Inhibitors, biology, Chemistry, HCT116 Cells, Xenograft Model Antitumor Assays, Bromodomain, Histone Deacetylase Inhibitors, 030104 developmental biology, Histone, Drug Resistance, Neoplasm, Acetylation, biology.protein, Cancer research, Histone deacetylase, Proto-Oncogene Proteins c-akt, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b4bef44299ade56993f92e5dd28e481
https://doi.org/10.1016/j.celrep.2021.108744

المؤلفون: Surbhi Sidana, Jacob J. Orme, Wilson I. Gonsalves

المصدر: Mayo Clinic proceedings. 93(10)

مصطلحات موضوعية: 0301 basic medicine, Image-Guided Biopsy, Male, medicine.medical_specialty, Amyloid, medicine.drug_class, Treatment outcome, Antineoplastic Agents, Gastroenterology, Dexamethasone, Bortezomib, 03 medical and health sciences, 0302 clinical medicine, Weight loss, Internal medicine, Natriuretic Peptide, Brain, Weight Loss, medicine, Natriuretic peptide, Humans, Immunoglobulin Light-chain Amyloidosis, Cyclophosphamide, Fatigue, Peritoneal Neoplasms, business.industry, General Medicine, Middle Aged, Immunohistochemistry, Peptide Fragments, 030104 developmental biology, Treatment Outcome, Splenomegaly, medicine.symptom, business, Cardiomyopathies, Tomography, X-Ray Computed, 030215 immunology, Hepatomegaly

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c36ab7c164bae3dd1f75a2bd792ae8b0
https://pubmed.ncbi.nlm.nih.gov/30104045

المؤلفون: Jacob J. Orme, Diana Purushotham

المصدر: The American Journal of Medicine. 130:e541-e542

مصطلحات موضوعية: medicine.medical_specialty, Lymphoma, B-Cell, medicine.diagnostic_test, business.industry, Physical examination, General Medicine, 030218 nuclear medicine & medical imaging, Surgery, 03 medical and health sciences, 0302 clinical medicine, Antineoplastic Combined Chemotherapy Protocols, Axilla, Hypercalcemia, medicine, Humans, Axillary mass, Female, 030212 general & internal medicine, Radiology, business, Value (mathematics), Aged

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::327751c2d66b5c84f5d43276ab57e3b3
https://doi.org/10.1016/j.amjmed.2017.06.023

المؤلفون: Cristina Arriens, Jessica M. Mayeux, Jack Hutcheson, Laurie S. Davis, Kamala Vanarsa, Anne B. Satterthwaite, Jacob J. Orme, Benjamin F. Chong, Yong Du, Chandra Mohan, So Youn Min, Azza Mutwally, Tianfu Wu, Li Li

المصدر: Clinical immunology (Orlando, Fla.). 169

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Mice, Inbred MRL lpr, ADAM10, Immunology, Blotting, Western, Gene Expression, Inflammation, Biology, ADAM17 Protein, Receptor tyrosine kinase, Article, Cell Line, 03 medical and health sciences, ADAM10 Protein, Young Adult, 0302 clinical medicine, immune system diseases, Proto-Oncogene Proteins, medicine, Immunology and Allergy, Animals, Humans, Lupus Erythematosus, Systemic, Receptor, skin and connective tissue diseases, Mice, Knockout, Systemic lupus erythematosus, AXL receptor tyrosine kinase, GAS6, Reverse Transcriptase Polymerase Chain Reaction, Macrophages, Receptor Protein-Tyrosine Kinases, Middle Aged, medicine.disease, Axl Receptor Tyrosine Kinase, Mice, Inbred C57BL, 030104 developmental biology, Ectodomain, 030220 oncology & carcinogenesis, biology.protein, Leukocytes, Mononuclear, Intercellular Signaling Peptides and Proteins, Female, medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba06d680848c099af507406eba91b7fe
https://pubmed.ncbi.nlm.nih.gov/27237127

المؤلفون: Kamala Vanarsa, Yong Du, Jacob J. Orme, Anne B. Satterthwaite, Chandra Mohan, Tianfu Wu

المصدر: PLoS ONE
PLoS ONE, Vol 11, Iss 8, p e0161682 (2016)

مصطلحات موضوعية: 0301 basic medicine, Male, lcsh:Medicine, Pathogenesis, medicine.disease_cause, Pathology and Laboratory Medicine, Biochemistry, Autoimmunity, Mice, White Blood Cells, Animal Cells, Transcriptional regulation, Leukocytes, Medicine and Health Sciences, Lupus Erythematosus, Systemic, Enzyme-Linked Immunoassays, lcsh:Science, skin and connective tissue diseases, Wnt Signaling Pathway, beta Catenin, Multidisciplinary, Systemic lupus erythematosus, biology, Wnt signaling pathway, Catenins, Animal Models, Intercellular Signaling Peptides and Proteins, Female, Cellular Types, Anatomy, Research Article, Beta-catenin, Follistatin-Related Proteins, Immune Cells, Immunology, Mice, Transgenic, Mouse Models, Research and Analysis Methods, Systemic Lupus Erythematosus, Autoimmune Diseases, 03 medical and health sciences, Model Organisms, Axin Protein, Rheumatology, medicine, Animals, Humans, Immunoassays, Lupus erythematosus, Blood Cells, Lupus Erythematosus, Macrophages, lcsh:R, Biology and Life Sciences, Proteins, Kidneys, Dendritic cell, Dendritic Cells, Cell Biology, Renal System, medicine.disease, Mice, Inbred C57BL, Wnt Proteins, Disease Models, Animal, Cytoskeletal Proteins, 030104 developmental biology, Gene Expression Regulation, Catenin, biology.protein, Immunologic Techniques, lcsh:Q, Clinical Immunology, Clinical Medicine, Gene Deletion, Spleen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa8e795a36850aeac9917df7c0e4bab7
https://pubmed.ncbi.nlm.nih.gov/27548498