المؤلفون: István Csabai, Judit Moldvay, János Fillinger, Zoltan Szallasi, Viktoria Tisza, Anders Gorm Pedersen, Marcin Krzystanek, Dávid Szüts, Miklos Diossy, Orsolya Rusz, Zsofia Sztupinszki, Judit Borcsok, József Tímár, Sándor Spisák

المصدر: npj Precision Oncology, Vol 5, Iss 1, Pp 1-8 (2021)
NPJ Precision Oncology
Diossy, M, Sztupinszki, Z, Borcsok, J, Krzystanek, M, Tisza, V, Spisak, S, Rusz, O, Timar, J, Csabai, I, Fillinger, J, Moldvay, J, Pedersen, A G, Szuts, D & Szallasi, Z 2021, ' A subset of lung cancer cases shows robust signs of homologous recombination deficiency associated genomic mutational signatures ', n p j Precision Oncology, vol. 5, no. 1, 55 . https://doi.org/10.1038/s41698-021-00199-8

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Biology, Article, Prostate cancer, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, SDG 3 - Good Health and Well-being, medicine, Lung cancer, Gene, Exome sequencing, Loss function, RC254-282, Lung, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, Squamous carcinoma, 030104 developmental biology, medicine.anatomical_structure, Oncology, chemistry, 030220 oncology & carcinogenesis, PARP inhibitor, Cancer research, Adenocarcinoma, Homologous recombination, Non-small-cell lung cancer, DNA

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b8487d7c44c3decc857387b2118d044
https://doaj.org/article/406462c44b26424ba7040c4796c0ef2d

المؤلفون: Matthew L. Freedman, Mark Pomerantz, Orsolya Rusz, Zsofia Sztupinszki, Sándor Spisák, Viktoria Tisza, Marcin Krzystanek, Miklos Diossy, Judit Borcsok, Zoltan Szallasi, István Csabai

المصدر: Clin Cancer Res

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Poly(ADP-ribose) Polymerase Inhibitors, Biology, medicine.disease_cause, Article, Germline, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Prostate, Exome Sequencing, Biomarkers, Tumor, medicine, Humans, Homologous Recombination, Gene, Exome sequencing, BRCA2 Protein, Mutation, BRCA1 Protein, Prostatic Neoplasms, Prognosis, medicine.disease, Gene Expression Regulation, Neoplastic, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, PARP inhibitor, Cancer research, Homologous recombination

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab2fd003cb36f7c422a938b5eac7bb6
https://doi.org/10.1158/1078-0432.ccr-19-2135

المؤلفون: Marcin Krzystanek, Aron Charles Eklund, István Csabai, Miklos Diossy, Anders Gorm Pedersen, Zoltan Szallasi, Zsofia Sztupinszki, Judit Borcsok

المصدر: Briefings in bioinformatics. 22(6)

مصطلحات موضوعية: Computer science, Posterior probability, Cytological Techniques, 03 medical and health sciences, 0302 clinical medicine, Cancer genome, Neoplasms, Databases, Genetic, Humans, Molecular Biology, Exome sequencing, 030304 developmental biology, 0303 health sciences, Artifact (error), Models, Statistical, Orientation (computer vision), business.industry, Detector, High-Throughput Nucleotide Sequencing, Reproducibility of Results, Pattern recognition, DNA, Neoplasm, Sequence Analysis, DNA, Templates, Genetic, Tissue specimen, 030220 oncology & carcinogenesis, Mutation (genetic algorithm), Mutation, Artificial intelligence, business, Artifacts, Algorithms, Information Systems

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ad93f6e799a883a7a64d322247fe09
https://pubmed.ncbi.nlm.nih.gov/34015811

المؤلفون: Dmitry Pruss, Zoltan Szallasi, Gábor Cserni, Janina Kulka, Kirsten Timms, Chris Neff, István Csabai, Orsolya Rusz, József Tímár, Cara Solimeno, Borbála Székely, Tamás Zombori, Miklos Diossy, Zsofia Sztupinszki, Marcin Krzystanek, Erika Tóth, Aron Charles Eklund, Orsolya Kiss, Lilla Reiniger

المصدر: Diossy, M, Reiniger, L, Sztupinszki, Z M, Krzystanek, M, Timms, K M, Neff, C, Solimeno, C, Pruss, D, Eklund, A C, Tóth, E, Kiss, O, Rusz, O, Cserni, G, Zombori, T, Székely, B, Tímár, J, Csabai, I & Szallasi, Z 2018, ' Breast cancer brain metastases show increased levels of genomic aberration based homologous recombination deficiency scores relative to their corresponding primary tumors ', Annals of Oncology, vol. 29, no. 9, pp. 1948-1954 . https://doi.org/10.1093/annonc/mdy216

مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, Cancer therapy, 03 medical and health sciences, Breast cancer, 0302 clinical medicine, SDG 3 - Good Health and Well-being, Internal medicine, DNA Mutational Analysis, medicine, Exome sequencing, business.industry, Brain metastasis, Hematology, medicine.disease, Primary tumor, Clinical trial, 030104 developmental biology, 030220 oncology & carcinogenesis, PARP inhibitor, Cohort, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9105edc33119ce50680dfa00aef0561c
https://doi.org/10.1093/annonc/mdy216

المؤلفون: Aron Charles Eklund, Ali Syed, Lilla Reiniger, Zoltan Szallasi, Miklos Diossy, Francesco Favero, Nicolai Juul Birkbak, Zsofia Sztupinszki, Marcin Krzystanek, István Csabai

المصدر: npj Breast Cancer, Vol 4, Iss 1, Pp 1-4 (2018)
Sztupinszki, Z, Diossy, M, Krzystanek, M, Reiniger, L, Csabai, I, Favero, F, Birkbak, N J, Eklund, A C, Syed, A & Szallasi, Z 2018, ' Migrating the SNP array-based homologous recombination deficiency measures to next generation sequencing data of breast cancer ', n p j Breast Cancer, vol. 4, 16 . https://doi.org/10.1038/s41523-018-0066-6
Sztupinszki, Z, Diossy, M, Krzystanek, M, Reiniger, L, Csabai, I, Favero, F, Birkbak, N J, Eklund, A C, Syed, A & Szallasi, Z 2018, ' Migrating the SNP array-based homologous recombination deficiency measures to next generation sequencing data of breast cancer ', npj Breast Cancer, vol. 4, no. 1, 16, pp. 1-4 . https://doi.org/10.1038/s41523-018-0066-6
NPJ Breast Cancer

مصطلحات موضوعية: 0301 basic medicine, Computational biology, Biology, Brief Communication, Genome, lcsh:RC254-282, DNA sequencing, 03 medical and health sciences, symbols.namesake, 0302 clinical medicine, Breast cancer, SDG 3 - Good Health and Well-being, medicine, SNP, Pharmacology (medical), Radiology, Nuclear Medicine and imaging, Exome, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Pearson product-moment correlation coefficient, Data set, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, symbols, SNP array

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd6f63d45f3b5971779e69de226b408
http://link.springer.com/article/10.1038/s41523-018-0066-6

المؤلفون: Thomas B.K. Watkins, Emilia L. Lim, Selvaraju Veeriah, István Csabai, Maria Greco, Nicholas McGranahan, Gareth A. Wilson, Stefan Boeing, Zoltan Szallasi, Jiri Bartek, Dhruva Biswas, Dijana Djureinovic, Maise Al Bakir, Allan Hackshaw, Charles Swanton, Christopher Abbosh, Rachel Rosenthal, Crispin T. Hiley, Javier Herrero, Krisztián Papp, Kevin Litchfield, Patrick Micke, Judit Moldvay, Balazs Dome, Arul M. Chinnaiyan, Yin Wu, Linnea La Fleur, Marcin Skrzypski, János Fillinger, Mariam Jamal-Hanjani, Marcin Krzystanek, Johan Botling, Nicolai Juul Birkbak, David Allan Moore, Hans Brunnström

المصدر: Biswas, D, Birkbak, N J, Rosenthal, R, Hiley, C T, Lim, E L, Papp, K, Boeing, S, Krzystanek, M, Djureinovic, D, La Fleur, L, Greco, M, Döme, B, Fillinger, J, Brunnström, H, Wu, Y, Moore, D A, Skrzypski, M, Abbosh, C, Litchfield, K, Al Bakir, M, Watkins, T B K, Veeriah, S, Wilson, G A, Jamal-Hanjani, M, Moldvay, J, Botling, J, Chinnaiyan, A M, Micke, P, Hackshaw, A, Bartek, J, Csabai, I, Szallasi, Z, Herrero, J, McGranahan, N, Swanton, C & TRACERx Consortium 2019, ' A clonal expression biomarker associates with lung cancer mortality ', Nature Medicine, vol. 25, no. 10, pp. 1540-1548 . https://doi.org/10.1038/s41591-019-0595-z

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, medicine.medical_specialty, Lung Neoplasms, Tumour heterogeneity, DNA Copy Number Variations, Disease, Biology, General Biochemistry, Genetics and Molecular Biology, Disease-Free Survival, Article, Transcriptome, Clonal Evolution, 03 medical and health sciences, Genetic Heterogeneity, 0302 clinical medicine, Risk Factors, Internal medicine, Exome Sequencing, medicine, Biomarkers, Tumor, Humans, Exome, Lung cancer, Exome sequencing, Aged, Genetic heterogeneity, Cancer, General Medicine, medicine.disease, Prognosis, Gene Expression Regulation, Neoplastic, 030104 developmental biology, 030220 oncology & carcinogenesis, Biomarker (medicine), Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2225be7c4547fd49cd0909f53c27198
https://pure.au.dk/portal/da/publications/a-clonal-expression-biomarker-associates-with-lung-cancer-mortality(a2adabfd-14ed-486e-b04b-03d3515e134f).html

المؤلفون: Lilla Reiniger, Dezső Ribli, Dávid Szüts, Zsofia Sztupinszki, Tibor Glasz, Marcin Krzystanek, István Csabai, Eszter Németh, Orsolya Pipek, Zoltan Szallasi, Judit Moldvay

المصدر: International journal of cancer. 145(3)

مصطلحات موضوعية: Cancer Research, Lung Neoplasms, Afatinib, Adenocarcinoma of Lung, medicine.disease_cause, 03 medical and health sciences, T790M, Genomic Imprinting, 0302 clinical medicine, medicine, Humans, Neoplasm Metastasis, Gene, Allele frequency, Protein Kinase Inhibitors, Retrospective Studies, Cisplatin, Gene Rearrangement, Mutation, Models, Genetic, business.industry, Cancer, Gefitinib, medicine.disease, ErbB Receptors, Oncology, Mutagenesis, 030220 oncology & carcinogenesis, Cancer research, Adenocarcinoma, business, Algorithms, medicine.drug, Genome-Wide Association Study

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e1763704639b7bd38786b95e181611c
https://pubmed.ncbi.nlm.nih.gov/30694556

المؤلفون: Nicolai Juul Birkbak, April Greene-Colozzi, Andrea L. Richardson, Nadine Tung, Marcin Krzystanek, James Dirk Iglehart, Matija Dreze, Zhenxiong Wang, Yi Li, Daniel P. Silver, P. D. Ryan, Christian Bowman-Colin, Shailja Pathania, Judy Garber, Zsofia Sztupinszki, Miklos Diossy, Dávid Szüts, Zoltan Szallasi

المصدر: Birkbak, N J, Li, Y, Pathania, S, Greene-Colozzi, A, Dreze, M, Bowman-Colin, C, Sztupinszki, Z, Krzystanek, M, Diossy, M, Tung, N, Ryan, P D, Garber, J E, Silver, D P, Iglehart, J D, Wang, Z C, Szuts, D, Szallasi, Z & Richardson, A L 2018, ' Overexpression of BLM promotes DNA damage and increased sensitivity to platinum salts in triple negative breast and serous ovarian cancers ', Annals of Oncology, vol. 29, no. 4, pp. 903-909 . https://doi.org/10.1093/annonc/mdy049
Annals of Oncology

مصطلحات موضوعية: 0301 basic medicine, DNA damage, DNA repair, Antineoplastic Agents, Platinum Compounds, Triple Negative Breast Neoplasms, 03 medical and health sciences, chemistry.chemical_compound, platinum based chemotherapy, SDG 3 - Good Health and Well-being, Fanconi anemia, Breast Tumors, medicine, Humans, platinum-based chemotherapy, gene expression-based predictor of treatment sensitivity, Triple-negative breast cancer, Cisplatin, Ovarian Neoplasms, Gene knockdown, RecQ Helicases, gene expression based predictor of treatment sensitivity, business.industry, Hematology, Original Articles, medicine.disease, 030104 developmental biology, ovarian cancer, Oncology, Paclitaxel, chemistry, triple negative breast cancer, Cancer research, triple-negative breast cancer, Female, business, Ovarian cancer, medicine.drug, DNA Damage

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd70a5a6791a61aa289aa2a6476e4d48
https://orbit.dtu.dk/en/publications/2d81ef14-e8b1-46c4-8ddc-387d560a35f0

المؤلفون: Emma Nye, Ben Phillimore, Nicholas McGranahan, Gordon Stamp, Archana Fernando, José I. López, Thomas B.K. Watkins, Hang Xu, Lisa Pickering, Kevin Litchfield, David Nicol, Sharmin Begum, Mariam Jamal-Hanjani, Lewis Au, Sharanpreet Lall, Lavinia Spain, Mary Varia, Nicolai Juul Birkbak, Steve Hazell, Eva Grönroos, Nicholas M. Luscombe, Mark Stares, Martin Gore, Alexander Polson, Aspasia Soultati, Ben Challacombe, Marcin Krzystanek, Nicos Fotiadis, Tim Chambers, Aengus Stewart, Ismaeel Aurangzeb, James Larkin, Dezso Ribli, Adam Huffman, Rachel Rosenthal, Orsolya Pipek, Max Salm, Peter J. Campbell, Charles Swanton, Catherine Horsfield, Samra Turajlic, Mickael Escudero, Bruno Silva, Faiz Jabbar, Thomas J. Mitchell, Zoltan Szallasi, Roland F. Schwarz, Simon Chowdhury, Sarkhara Sharma, Ashish Chandra, Sebastijan Hobor, Stuart Horswell, Wei Xing, Gareth A. Wilson, Sophia Ward, Tim O'Brien, Stefan Boeing, Claudia Eichler-Jonsson, Javier Herrero, Andrew Rowan, Nik Matthews, István Csabai, Peter Van Loo, Jonathan C. Smith, Carolina Navas, Greg Elgar, Joanna Lynch, Marta Costa, Sarah Rudman, Rosalie Fisher

المصدر: Turajlic, S, Xu, H, Litchfield, K, Rowan, A, Horswell, S, Chambers, T, O'Brien, T, Lopez, J I, Watkins, T B K, Nicol, D, Stares, M, Challacombe, B, Hazell, S, Chandra, A, Mitchell, T J, Au, L, Eichler-Jonsson, C, Jabbar, F, Soultati, A, Chowdhury, S, Rudman, S, Lynch, J, Fernando, A, Stamp, G, Nye, E, Stewart, A, Xing, W, Smith, J C, Escudero, M, Huffman, A, Matthews, N, Elgar, G, Phillimore, B, Costa, M, Begum, S, Ward, S, Salm, M, Boeing, S, Fisher, R, Spain, L, Navas, C, Grönroos, E, Hobor, S, Sharma, S, Aurangzeb, I, Lall, S, Polson, A, Varia, M, Horsfield, C, Fotiadis, N, Pickering, L, Schwarz, R F, Silva, B, Herrero, J, Luscombe, N M, Jamal-Hanjani, M, Rosenthal, R, Birkbak, N J, Wilson, G A, Ribli, D, Pipek, O, Krzystanek, M, Csabai, I, Szallasi, Z I, Gore, M, McGranahan, N, Van Loo, P, Campbell, P, Larkin, J & Swanton, C 2018, ' Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal ', Cell, vol. 173, no. 3, e11, pp. 595-610 . https://doi.org/10.1016/j.cell.2018.03.043
Addi. Archivo Digital para la Docencia y la Investigación
instname

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, cell carcinoma, Computational biology, Biology, rhabdoid differentiation, Somatic evolution in cancer, General Biochemistry, Genetics and Molecular Biology, copy-number alterations, 03 medical and health sciences, Renal cell carcinoma, medicine, BAP1, Allele, gene, Genetic heterogeneity, active surveillance, driver mutation, sequencing data, kidney cancer, medicine.disease, Primary tumor, international society, 3. Good health, 030104 developmental biology, Biomarker (medicine), Kidney cancer

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d622d9e406e6e2589f5c1f9901f920d3
https://orbit.dtu.dk/en/publications/0283a41f-f3c8-4e43-bf37-e06dbf418c61

المؤلفون: Charles Swanton, Zoltan Szallasi, Gábor E. Tusnády, Dávid Szüts, Marcin Krzystanek, János Molnár, Orsolya Pipek, István Csabai, Ádám Póti, Nnennaya Kanu

المصدر: G3: Genes|Genomes|Genetics
Molnar, J, Poti, A, Pipek, O, Krzystanek, M, Kanu, N, Swanton, C, Tusnady, G E, Szallasi, Z I, Csabai, I & Szuets, D 2014, ' The Genome of the Chicken DT40 Bursal Lymphoma Cell Line ', G3: Genes, Genomes, Genetics (Bethesda), vol. 4, no. 11, pp. 2231-2240 . https://doi.org/10.1534/g3.114.013482

مصطلحات موضوعية: Cancer genome sequencing, Genome evolution, Lymphoma, Karyotype, Biology, Investigations, Genome, Polymorphism, Single Nucleotide, gene targeting, Proto-Oncogene Proteins c-myc, 03 medical and health sciences, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, single nucleotide polymorphism, Gene density, Cell Line, Tumor, Genetics, Animals, tumor suppressor gene, Molecular Biology, Gene, Genetics (clinical), 030304 developmental biology, 0303 health sciences, Shotgun sequencing, DT40, DNA Helicases, Genome project, chicken genome, Gene Expression Regulation, Neoplastic, Mutagenesis, Insertional, 030220 oncology & carcinogenesis, Chickens, Gene Deletion, Reference genome

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::683bba59733bb8139c6814dac94fbec9
http://europepmc.org/articles/PMC4232548