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المؤلفون: Angelica Hollunder Klippel, Elizabeth Bilsland, Sandro Roberto Valentini, Rafael M. Couñago, Mario H. Bengtson, Suelen Fernandes Silva, Andree da Silva Santiago, Katlin B. Massirer, Cleslei Fernando Zanelli, P.Z. Ramos
المساهمون: Universidade Estadual Paulista (Unesp), Universidade Estadual de Campinas (UNICAMP)
المصدر: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
PLoS Neglected Tropical Diseases, Vol 14, Iss 10, p e0008762 (2020)
PLoS Neglected Tropical Diseasesمصطلحات موضوعية: 0301 basic medicine, Nematoda, RC955-962, Drug Evaluation, Preclinical, Protozoan Proteins, Yeast and Fungal Models, Biochemistry, Brugia malayi, chemistry.chemical_compound, 0302 clinical medicine, Arctic medicine. Tropical medicine, Deoxyhypusine synthase, Leishmania major, Brugia Malayi, Enzyme Inhibitors, Enzyme Chemistry, Protozoans, Anthelmintics, Oxidoreductases Acting on CH-NH Group Donors, Crystallography, biology, Physics, Biochemical Cofactors, Eukaryota, Helminth Proteins, Condensed Matter Physics, Enzymes, Infectious Diseases, Bioassays and Physiological Analysis, Experimental Organism Systems, Physical Sciences, Crystal Structure, Saccharomyces Cerevisiae, Public aspects of medicine, RA1-1270, EIF5A, Research Article, Trypanosoma, 030231 tropical medicine, Saccharomyces cerevisiae, Antiprotozoal Agents, Research and Analysis Methods, 03 medical and health sciences, Saccharomyces, Eukaryotic translation, Model Organisms, Brugia, Trypanosoma Brucei, Solid State Physics, Animals, Amino Acid Sequence, Gene, Enzyme Assays, Hypusine, Public Health, Environmental and Occupational Health, Organisms, Fungi, Biology and Life Sciences, Proteins, biology.organism_classification, Invertebrates, Yeast, Parasitic Protozoans, High-Throughput Screening Assays, 030104 developmental biology, chemistry, biology.protein, Animal Studies, Enzymology, Biochemical Analysis, Zoology, Sequence Alignment, Trypanosoma Brucei Gambiense
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5421839c45df0419889cf3653f751e91
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المؤلفون: Harry P. de Koning, Fabio Zuccotto, Juan A. Bueren-Calabuig, Juan F. Quintana, Mark C. Field, David Horn
المصدر: PLoS Neglected Tropical Diseases, Vol 14, Iss 7, p e0008458 (2020)
PLoS Neglected Tropical Diseasesمصطلحات موضوعية: Glycerol, 0301 basic medicine, RC955-962, Drug Resistance, Drug resistance, Endoplasmic Reticulum, Biochemistry, 0302 clinical medicine, Ubiquitin, Arctic medicine. Tropical medicine, Amino Acids, Protozoans, 0303 health sciences, Secretory Pathway, biology, Protein Stability, Organic Compounds, Chemistry, Monomers, Eukaryota, ER retention, Trypanocidal Agents, Endocytosis, 3. Good health, Cell biology, Infectious Diseases, medicine.anatomical_structure, Drug development, Cell Processes, Physical Sciences, Cellular Structures and Organelles, Basic Amino Acids, Public aspects of medicine, RA1-1270, Aquaglyceroporins, Research Article, medicine.drug, Trypanosoma, Endosome, Trypanosoma brucei brucei, Immunoblotting, 030231 tropical medicine, Glycerol transport, Molecular Probe Techniques, Trypanosoma brucei, Research and Analysis Methods, 03 medical and health sciences, Lysosome, Trypanosoma Brucei, medicine, Animals, Amino Acid Sequence, Molecular Biology Techniques, Molecular Biology, 030304 developmental biology, 030306 microbiology, Lysine, Organic Chemistry, Organisms, Chemical Compounds, Public Health, Environmental and Occupational Health, Biology and Life Sciences, Proteins, Cell Biology, Polymer Chemistry, biology.organism_classification, Parasitic Protozoans, Trypanosomiasis, African, 030104 developmental biology, biology.protein, Lysosomes, Trypanosoma Brucei Gambiense, Pentamidine
وصف الملف: application/pdf
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المؤلفون: Stefan Magez, Carl De Trez, Shahid M. Khan
المساهمون: Department of Bio-engineering Sciences, Cellular and Molecular Immunology
المصدر: PLOS NEGLECTED TROPICAL DISEASES
PLoS Neglected Tropical Diseases, Vol 14, Iss 6, p e0008358 (2020)
PLoS Neglected Tropical Diseasesمصطلحات موضوعية: Protozoan Vaccines, 0301 basic medicine, B Cells, Physiology, RC955-962, Antibodies, Protozoan, Plasma cell, Lymphocyte Activation, Biochemistry, White Blood Cells, Mice, 0302 clinical medicine, Animal Cells, Immune Physiology, Arctic medicine. Tropical medicine, Medicine and Health Sciences, Enzyme-Linked Immunoassays, Alum adjuvant, Memory B cell, Protozoans, B-Lymphocytes, Mice, Inbred BALB C, Immune System Proteins, biology, Malarial Parasites, Eukaryota, medicine.anatomical_structure, Infectious Diseases, Female, Public Health, Cellular Types, Public aspects of medicine, RA1-1270, Antibody, Genetic Background, Research Article, Trypanosoma, ANTIBODY-RESPONSES, Immune Cells, Immunology, Plasma Cells, Trypanosoma brucei brucei, 030231 tropical medicine, B-Lymphocyte Subsets, Antigens, Protozoan, Trypanosoma brucei, Research and Analysis Methods, Antibodies, Host-Parasite Interactions, 03 medical and health sciences, Immune system, Antigen, VARIANT SURFACE GLYCOPROTEIN, Parasitic Diseases, Trypanosoma Brucei, medicine, Animals, Antibody-Producing Cells, Immunoassays, B cell, Immune Evasion, Blood Cells, Environmental and Occupational Health, Organisms, Public Health, Environmental and Occupational Health, Proteins, Biology and Life Sciences, Cell Biology, GAMMA, biology.organism_classification, Parasitic Protozoans, Immunity, Humoral, Mice, Inbred C57BL, Disease Models, Animal, Trypanosomiasis, African, 030104 developmental biology, Immunoglobulin G, Immunologic Techniques, biology.protein, MARGINAL ZONE, Trypanosoma Brucei Gambiense
وصف الملف: application/pdf
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المؤلفون: Emir Salas-Sarduy, Lionel Urán Landaburu, Juan José Cazzulo, Gabriela T. Niemirowicz, Fernán Agüero, Adriana K. Carmona, Vanina E. Alvarez
المصدر: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 13, Iss 7, p e0007560 (2019)مصطلحات موضوعية: 0301 basic medicine, RC955-962, Protozoan Proteins, Carboxypeptidases, Biochemistry, Physical Chemistry, Fluorophotometry, purl.org/becyt/ford/1 [https], 0302 clinical medicine, Protein sequencing, Spectrum Analysis Techniques, Arctic medicine. Tropical medicine, Drug Discovery, Medicine and Health Sciences, Fluorescence Resonance Energy Transfer, Enzyme Inhibitors, chemistry.chemical_classification, Protozoans, biology, Neglected Diseases, Eukaryota, INHIBITOR, Enzyme structure, Enzymes, Chemistry, Infectious Diseases, Spectrophotometry, Physical Sciences, Public aspects of medicine, RA1-1270, Research Article, Neglected Tropical Diseases, Chagas disease, Trypanosoma, CARBOXYPEPTIDASE, Antiparasitic, medicine.drug_class, High-throughput screening, Trypanosoma cruzi, 030231 tropical medicine, Trypanosoma brucei brucei, Trypanosoma brucei, Research and Analysis Methods, Fluorescence, Host-Parasite Interactions, 03 medical and health sciences, Inhibitory Concentration 50, parasitic diseases, medicine, Trypanosoma Brucei, Parasitic Diseases, Humans, Chagas Disease, purl.org/becyt/ford/1.6 [https], Protozoan Infections, Chemical Bonding, Public Health, Environmental and Occupational Health, Organisms, Biology and Life Sciences, Proteins, Hydrogen Bonding, TRYPANOSOMA, biology.organism_classification, medicine.disease, Tropical Diseases, Parasitic Protozoans, High-Throughput Screening Assays, 030104 developmental biology, Enzyme, chemistry, Enzyme Structure, Enzymology, Trypanosoma Brucei Gambiense
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f82d557d2d9a265b8dce6af2420bde
http://dx.plos.org/10.1371/journal.pntd.0007560 -
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المؤلفون: Sabine Kuettel, Michele Tinti, Michael A. J. Ferguson, Alan R. Prescott, Maria Lucia S. Güther
المصدر: PLoS Neglected Tropical Diseases, Vol 15, Iss 2, p e0009132 (2021)
PLoS Neglected Tropical Diseasesمصطلحات موضوعية: 0301 basic medicine, Cell Membranes, RC955-962, Nucleotide sugar, Microbodies, Biochemistry, chemistry.chemical_compound, Fluorescence Microscopy, Mutase, Arctic medicine. Tropical medicine, Protozoans, Microscopy, biology, Nucleotides, Eukaryota, Light Microscopy, Peroxisome, 3. Good health, Infectious Diseases, Cellular Structures and Organelles, Public aspects of medicine, RA1-1270, Research Article, Immunofluorescence Microscopy, Trypanosoma, Trypanosoma brucei brucei, 030106 microbiology, Trypanosoma brucei, Biosynthesis, Research and Analysis Methods, Glycosome, 03 medical and health sciences, Organelle, Trypanosoma Brucei, Life Cycle Stages, Organisms, Public Health, Environmental and Occupational Health, Biology and Life Sciences, Membrane Proteins, Cell Biology, biology.organism_classification, Parasitic Protozoans, carbohydrates (lipids), 030104 developmental biology, chemistry, Sugars, Trypanosoma Brucei Gambiense
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المؤلفون: Ralph Minter, Steven Rust, Matthew K. Higgins, Arnaud Tiberghien, Katrien Van Bocxlaer, Amanda F. Francisco, Alan Sandercock, Conor S. Barry, Tristan J. Vaughan, Fatoumatta Jobe, Andrea L. Gonzalez-Munoz, Martin C. Taylor, Olivia J. S. Macleod, Philip W. Howard, Paula MacGregor, Mark Carrington, Francois D'Hooge
المساهمون: MacGregor, Paula [0000-0003-0919-3745], Macleod, Olivia JS [0000-0002-5747-8019], Tiberghien, Arnaud [0000-0002-2936-0515], Carrington, Mark [0000-0002-6435-7266], Apollo - University of Cambridge Repository
المصدر: PLoS Neglected Tropical Diseases, Vol 13, Iss 5, p e0007373 (2019)
PLoS Neglected Tropical Diseasesمصطلحات موضوعية: 0301 basic medicine, Physiology, RC955-962, Toxicology, Pathology and Laboratory Medicine, Biochemistry, law.invention, Benzodiazepines, Mice, 0302 clinical medicine, law, Immune Physiology, Arctic medicine. Tropical medicine, Medicine and Health Sciences, Toxins, African trypanosomiasis, Protozoans, 0303 health sciences, Mice, Inbred BALB C, Immune System Proteins, biology, Antibodies, Monoclonal, Eukaryota, Animal Models, 3. Good health, Infectious Diseases, Experimental Organism Systems, Recombinant DNA, Female, Antibody, Public aspects of medicine, RA1-1270, Research Article, Trypanosoma, Antibody-drug conjugate, medicine.drug_class, Trypanosoma brucei brucei, Toxic Agents, Immunology, 030231 tropical medicine, Antiprotozoal Agents, Mouse Models, Trypanosoma brucei, Research and Analysis Methods, Monoclonal antibody, Microbiology, Antibodies, 03 medical and health sciences, Model Organisms, Therapeutic index, parasitic diseases, Trypanosoma Brucei, Parasitic Diseases, medicine, Animals, Humans, Pyrroles, Animal Models of Disease, 030304 developmental biology, business.industry, Organisms, Public Health, Environmental and Occupational Health, Biology and Life Sciences, Proteins, medicine.disease, biology.organism_classification, Virology, Parasitic Protozoans, Animal Models of Infection, Trypanosomiasis, African, 030104 developmental biology, biology.protein, Animal Studies, business, Trypanosomiasis, Trypanosoma Brucei Gambiense, Conjugate
وصف الملف: application/pdf
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المؤلفون: Corinna Benz, Nadin Fathallah, Henry J Benns, Ashley Connor-Guscott, Winston Lo, Michael D. Urbaniak
المصدر: PLoS ONE
PLoS ONE, Vol 13, Iss 12, p e0206332 (2018)مصطلحات موضوعية: 0301 basic medicine, Protozoan Proteins, Gene Expression, Biochemistry, Green fluorescent protein, Cell Fusion, Database and Informatics Methods, Post-Transcriptional Gene Regulation, 3' Untranslated Regions, Protozoans, Regulation of gene expression, 2. Zero hunger, chemistry.chemical_classification, 0303 health sciences, Multidisciplinary, biology, Messenger RNA, 030302 biochemistry & molecular biology, Eukaryota, Iron Deficiencies, Enzymes, Cell biology, Nucleic acids, Ribosomal RNA, Medicine, Oxidoreductases, Luciferase, Sequence Analysis, Research Article, Trypanosoma, Cell Physiology, Cellular structures and organelles, Bioinformatics, Science, Trypanosoma brucei brucei, Transferrin receptor, Trypanosoma brucei, Research and Analysis Methods, Endocytosis, Cell Line, 03 medical and health sciences, Downregulation and upregulation, Gene Types, Receptors, Transferrin, Trypanosoma Brucei, Genetics, Humans, Gene Regulation, Non-coding RNA, 030304 developmental biology, Reporter gene, Organisms, Biology and Life Sciences, Proteins, Cell Biology, biology.organism_classification, Parasitic Protozoans, 030104 developmental biology, Gene Expression Regulation, chemistry, Transferrin, Enzymology, RNA, Sequence Alignment, Ribosomes, Trypanosoma Brucei Gambiense, Reporter Genes
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07688f03d5f38b25d4878896dc7cacb3
https://doi.org/10.1101/441931 -
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المؤلفون: Sanaa S. Botros, Harry P. de Koning, Geert Jan Sterk, Titilola D. Kalejaiye, Sheng Xiang Huang, Zainab Abbasi, Jane C. Munday, Samia William, Susanne Schroeder, David G. Brown, Marco Siderius, Abdel-Nasser A. Sabra, Ali H. Alghamdi, Anne M. Donachie, Stefan Kunz, Daniel Paape, Rob Leurs, Charles S. Hoffman
المساهمون: AIMMS, Medicinal chemistry
المصدر: PLoS Neglected Tropical Diseases, Vol 14, Iss 7, p e0008447 (2020)
PLoS Neglected Tropical Diseases
Munday, J C, Kunz, S, Kalejaiye, T D, Siderius, M, Schroeder, S, Paape, D, Alghamdi, A H, Abbasi, Z, Huang, S X, Donachie, A M, William, S, Sabra, A N, Sterk, G J, Botros, S S, Brown, D G, Hoffman, C S, Leurs, R & de Koning, H P 2020, ' Cloning and functional complementation of ten Schistosoma mansoni phosphodiesterases expressed in the mammalian host stages ', PLoS Neglected Tropical Diseases, vol. 14, no. 7, e0008447, pp. 1-29 . https://doi.org/10.1371/journal.pntd.0008447
PLoS Neglected Tropical Diseases, 14(7):e0008447, 1-29. Public Library of Scienceمصطلحات موضوعية: Male, 0301 basic medicine, Schistosoma Mansoni, RC955-962, Yeast and Fungal Models, Biochemistry, Schizosaccharomyces Pombe, Mice, 0302 clinical medicine, Yeasts, Arctic medicine. Tropical medicine, Invertebrate Genomics, Cloning, Molecular, Phylogeny, Protozoans, biology, Cyclic nucleotide phosphodiesterase, Drug discovery, Eukaryota, Phosphodiesterase, Genomics, Helminth Proteins, Enzymes, Complementation, Infectious Diseases, Experimental Organism Systems, Drug development, Phosphodiesterases, Schistosoma, Saccharomyces Cerevisiae, Gene Cloning, Schistosoma mansoni, Public aspects of medicine, RA1-1270, Research Article, Trypanosoma, Trypanosoma brucei brucei, 030231 tropical medicine, Molecular cloning, Research and Analysis Methods, Gene Expression Regulation, Enzymologic, Cell Line, Saccharomyces, 03 medical and health sciences, Model Organisms, SDG 3 - Good Health and Well-being, Helminths, Schizosaccharomyces, parasitic diseases, Genetics, Trypanosoma Brucei, Animals, Molecular Biology Techniques, Molecular Biology, Gene, Genome, Helminth, Phosphoric Diester Hydrolases, Gene Expression Profiling, Organisms, Fungi, Public Health, Environmental and Occupational Health, Biology and Life Sciences, Proteins, biology.organism_classification, Invertebrates, Yeast, Parasitic Protozoans, 030104 developmental biology, Animal Genomics, Animal Studies, Enzymology, Zoology, Gene Deletion, Trypanosoma Brucei Gambiense, Cloning
وصف الملف: application/pdf
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المؤلفون: Vanina E. Alvarez, Javier G. De Gaudenzi, María Agustina Berazategui, Paula Ana Iribarren, Lucía Ayelén Di Marzio
المصدر: CIC Digital (CICBA)
Comisión de Investigaciones Científicas de la Provincia de Buenos Aires
instacron:CICBA
PLoS ONE, Vol 13, Iss 2, p e0193528 (2018)
PLoS ONE
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICETمصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Amino Acid Motifs, Biotecnología del Medio Ambiente, Lysine, SUMO protein, Gene Expression, lcsh:Medicine, Biochemistry, purl.org/becyt/ford/1 [https], Database and Informatics Methods, Amino Acids, lcsh:Science, Protozoans, Multidisciplinary, biology, Organic Compounds, Chromosome Biology, Chemistry, Eukaryota, Bioquímica y Biología Molecular, SUMOylation, Chromatin, Cell biology, Synaptonemal complex, Telomeres, Physical Sciences, Small Ubiquitin-Related Modifier Proteins, Epigenetics, Post-translational modification, Basic Amino Acids, Sequence Analysis, CIENCIAS NATURALES Y EXACTAS, Research Article, Trypanosoma, Chromosome Structure and Function, Bioinformatics, Transgene, Trypanosoma brucei brucei, Saccharomyces cerevisiae, SUMO CHAINS, Trypanosoma brucei, Research and Analysis Methods, Chromosomes, Ciencias Biológicas, 03 medical and health sciences, Protein Domains, Sequence Motif Analysis, Trypanosoma Brucei, Genetics, Amino Acid Sequence, purl.org/becyt/ford/1.6 [https], Protein Structure, Quaternary, Cell Nucleus, Biology and life sciences, Organic Chemistry, lcsh:R, Organisms, Chemical Compounds, Proteins, Cell Biology, TRYPANOSOMA, Subcellular localization, biology.organism_classification, Parasitic Protozoans, NUCLEAR FOCI, 030104 developmental biology, Mutation, CHROMATIN ORGANIZATION, lcsh:Q, Protein Multimerization, Trypanosoma Brucei Gambiense
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b00ba236a89868c567b649baaab38891
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0193528 -
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المصدر: PLoS Pathogens
PLoS Pathogens, Vol 14, Iss 5, p e1007101 (2018)مصطلحات موضوعية: 0301 basic medicine, Transcription Elongation, Genetic, Protozoan Proteins, Kinesins, Cell morphology, Pathology and Laboratory Medicine, Biochemistry, Protein Structure, Secondary, RNA interference, Medicine and Health Sciences, Cytoskeleton, Procyclin, lcsh:QH301-705.5, Protozoans, Membrane Glycoproteins, biology, Chemistry, musculoskeletal, neural, and ocular physiology, Microtubule Motors, Eukaryota, Cell biology, Precipitation Techniques, Nucleic acids, Genetic interference, Flagella, Kinesin, Epigenetics, Cellular Structures and Organelles, Pathogens, Research Article, lcsh:Immunologic diseases. Allergy, Pathogen Motility, Trypanosoma, Virulence Factors, Immunology, Trypanosoma brucei brucei, Importin, Trypanosoma brucei, Flagellum, Research and Analysis Methods, Microbiology, 03 medical and health sciences, Molecular Motors, Virology, Genetics, Trypanosoma Brucei, Immunoprecipitation, Amino Acid Sequence, Molecular Biology, urogenital system, Organisms, Biology and Life Sciences, Proteins, Cell Biology, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, Parasitic Protozoans, Cytoskeletal Proteins, 030104 developmental biology, Kinetoplasts, lcsh:Biology (General), bacteria, RNA, Parasitology, Gene expression, lcsh:RC581-607, Carrier Proteins, Sequence Alignment, Trypanosoma Brucei Gambiense
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