المؤلفون: Péter Hegyi, Andrea Szentesi, Áron Vincze, Eszter Hegyi, Anna Zsófia Tóth, Miklós Sahin-Tóth

المصدر: Gut. 69:1713-1715

مصطلحات موضوعية: 0301 basic medicine, Genetics, Trypsinogen, Haplotype, Gastroenterology, Locus (genetics), Genome-wide association study, Biology, medicine.disease, Trypsin, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, chemistry, medicine, Pancreatitis, PRSS2, 030211 gastroenterology & hepatology, Allele, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fb01056383518d0180cc5f9e8e68219a
https://doi.org/10.1136/gutjnl-2019-319729

المؤلفون: Miklós Sahin-Tóth, Eszter Hegyi, Zsanett Jancsó

المصدر: Gastroenterology. 155:1017-1021

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Proteolysis, medicine.medical_treatment, Chymotrypsinogen, Arginine, Severity of Illness Index, Article, 03 medical and health sciences, Internal medicine, Enzyme Stability, medicine, Animals, Chymotrypsin, Trypsin, Pancreas, Mice, Knockout, Protease, Hepatology, biology, medicine.diagnostic_test, Chemistry, Chymotrypsin-C, Gastroenterology, medicine.disease, Enzyme Activation, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Endocrinology, Pancreatitis, biology.protein, Female, Secretagogue, Ceruletide, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e913c38a7dd946197177a4c5c2b20142
https://doi.org/10.1053/j.gastro.2018.06.041

المؤلفون: Miklós Sahin-Tóth, Eszter Hegyi

المصدر: Gut. 68:301-312

مصطلحات موضوعية: 0301 basic medicine, Hereditary pancreatitis, Pancreatic disease, business.industry, Gastroenterology, medicine.disease, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Fibrosis, Metaplasia, Cancer research, medicine, Acinar cell, Unfolded protein response, Pancreatitis, 030211 gastroenterology & hepatology, medicine.symptom, Pancreas, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5a80701a5c9624a41091ae3c0d40c4fa
https://doi.org/10.1136/gutjnl-2018-315994

المؤلفون: Daizhan Zhou, Liang-Hao Hu, Miklós Sahin-Tóth, Wen-Bin Zou, An-Jing Zhao, Andrea Geisz, Xiao-Tian Sun, Zhuan Liao, Zhen-Hua Zhao, Hao Wu, Zhao-Shen Li, David Neil Cooper, Lin He, Jian-Min Chen, Dorottya Berki, Claude Férec

المصدر: Human Mutation. 38:959-963

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Carboxypeptidases A, Genotype, Idiopathic chronic pancreatitis, Population, Biology, Bioinformatics, Gastroenterology, Article, DNA sequencing, Cohort Studies, 03 medical and health sciences, symbols.namesake, Asian People, Pancreatitis, Chronic, Internal medicine, Genetics, medicine, Humans, Missense mutation, Genetic Predisposition to Disease, education, Gene, Genetics (clinical), Sanger sequencing, education.field_of_study, medicine.disease, R1, 030104 developmental biology, Mutation, Cohort, symbols, Pancreatitis, Female

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5c112149fc12c60484240b0751e70d
https://doi.org/10.1002/humu.23254

المؤلفون: Zsanett Jancsó, Miklós Sahin-Tóth

المصدر: Gastroenterology

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Trypsinogen, Severity of Illness Index, Article, Cathepsin B, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Edema, Internal medicine, Pancreatitis, Chronic, medicine, Animals, Trypsin, Pancreas, Hepatology, biology, business.industry, Secretagogues, Gastroenterology, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, chemistry, Pancreatitis, Myeloperoxidase, Mutation, biology.protein, Acute pancreatitis, 030211 gastroenterology & hepatology, medicine.symptom, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1290fb2b4ee5ab1ba7d48cb2a37b24b3
https://pubmed.ncbi.nlm.nih.gov/31911102

المؤلفون: Péter Hegyi, Miklós Sahin-Tóth, Balázs Németh, Ákos Szücs

المصدر: American Journal of Gastroenterology. 112:1896-1898

مصطلحات موضوعية: 0301 basic medicine, Hepatology, business.industry, Gastroenterology, medicine.disease, digestive system, Article, digestive system diseases, 03 medical and health sciences, 030104 developmental biology, Mutation (genetic algorithm), Cancer research, Trypsinogen activation peptide, Medicine, Pancreatitis, Medical science, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8cfae0574886ecd055b6cbe651144c0
https://doi.org/10.1038/ajg.2017.393

المؤلفون: Miklós Sahin-Tóth, Péter Hegyi, Anita Balázs

المصدر: American Journal of Physiology-Gastrointestinal and Liver Physiology. 310:G477-G486

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Protein Folding, Protein Conformation, Physiology, Trypsinogen, Trypsin inhibitor, Biology, Transfection, Substrate Specificity, Protein Aggregates, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Pancreatitis, Chronic, Physiology (medical), medicine, Chymotrypsin, Humans, Genetic Predisposition to Disease, Trypsin, Trypsinogen activation, Pancreatitis, chronic, Genetics, Hereditary pancreatitis, Binding Sites, Hepatology, Gastroenterology, Pancreatic Physiology/Pathophysiology, Endoplasmic Reticulum Stress, medicine.disease, Molecular biology, Enzyme Activation, Kinetics, HEK293 Cells, Phenotype, 030104 developmental biology, chemistry, Trypsin Inhibitor, Kazal Pancreatic, Mutation, Unfolded protein response, Pancreatitis, Carrier Proteins, Protein Binding, Signal Transduction, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e761c5f9e6aba59c4f8b1f9423f6d2
https://doi.org/10.1152/ajpgi.00444.2015

المؤلفون: James R. A. Skipworth, Sebastian Krug, Florence Bühler, Sebastian Gimpfl, Joachim Mössner, Anke Tönjes, Atsushi Masamune, Adrian Saftoiu, Roland H. Pfützer, Marcella Rietschel, Heiko Witt, Felix Stickel, Jens Werner, Peter Kovacs, Nicole Soranzo, Constantin Zimmer, Martin Ziegler, Helmut Laumen, Holger Kirsten, Marco J. Bruno, Joost P.H. Drenth, Markus M. Lerch, Markus M. Nöthen, Claus Hellerbrand, Annette Peters, Philippe Lévy, Jian-Min Chen, Monika Ridinger, Giulia Martina Cavestro, Emmanuelle Masson, Milena Di Leo, Peter Simon, Peter Bugert, Péter Hegyi, Karl Mann, Miklós Sahin-Tóth, Pier Alberto Testoni, Núria Malats, Rene H. M. te Morsche, Konstantin Strauch, Stephen P. Pereira, Josef Frank, Norbert Wodarz, Halina Cichoż-Lach, Jonas Rosendahl, Alexander Schneider, Marcus Hollenbach, Olfert Landt, Markus Löffler, Sergio Pedrazzoli, Volker Keim, Matthias Löhr, Marie Motyka, Sebastian Mueller, Ralph Burkhardt, Antoni Farré, Heidi Griesmann, Falk Kiefer, Giovanni Malerba, Claudia Ruffert, Markus Scholz, Francisco X. Real, Maren Ludwig, Eszter Hegyi, Harald Grallert, Hana Algül, Vinciane Rebours, Eva Rösmann, Frank Ulrich Weiss, Sonja Mohr, Robert Grützmann, Sevastitia Iordache, Michael Soyka, Milan Macek, Peter Lichtner, Patrick Michl, Claude Férec, Giovanni Gambaro, Michael Stumvoll, Katharina Seltsam, Thomas Müller, Grazyna Jurkowska, Ewa Małecka-Panas, Sebastian Beer, Julia Mayerle, Hans-Ulrich Schulz, Lena Werner

المساهمون: Publica, Rosendahl, Jona, Kirsten, Holger, Hegyi, Eszter, Kovacs, Peter, Weiss, Frank Ulrich, Laumen, Helmut, Lichtner, Peter, Ruffert, Claudia, Chen, Jian min, Masson, Emmanuelle, Beer, Sebastian, Zimmer, Constantin, Seltsam, Katharina, Algül, Hana, Bühler, Florence, Bruno, Marco J, Bugert, Peter, Burkhardt, Ralph, Cavestro, GIULIA MARTINA, Cichoz lach, Halina, Farré, Antoni, Frank, Josef, Gambaro, Giovanni, Gimpfl, Sebastian, Grallert, Harald, Griesmann, Heidi, Grützmann, Robert, Hellerbrand, Clau, Hegyi, Péter, Hollenbach, Marcu, Iordache, Sevastitia, Jurkowska, Grazyna, Keim, Volker, Kiefer, Falk, Krug, Sebastian, Landt, Olfert, Leo, Milena Di, Lerch, Markus M, Lévy, Philippe, Löffler, Marku, Löhr, Matthia, Ludwig, Maren, Macek, Milan, Malats, Nuria, Malecka panas, Ewa, Malerba, Giovanni, Mann, Karl, Mayerle, Julia, Mohr, Sonja, Te Morsche, Rene H. M, Motyka, Marie, Mueller, Sebastian, Müller, Thoma, Nöthen, Markus M, Pedrazzoli, Sergio, Pereira, Stephen P, Peters, Annette, Pfützer, Roland, Real, Francisco X, Rebours, Vinciane, Ridinger, Monika, Rietschel, Marcella, Rösmann, Eva, Saftoiu, Adrian, Schneider, Alexander, Schulz, Hans ulrich, Soranzo, Nicole, Soyka, Michael, Simon, Peter, Skipworth, Jame, Stickel, Felix, Strauch, Konstantin, Stumvoll, Michael, Testoni, PIER ALBERTO, Tönjes, Anke, Werner, Lena, Werner, Jen, Wodarz, Norbert, Ziegler, Martin, Masamune, Atsushi, Mössner, Joachim, Férec, Claude, Michl, Patrick, Joost, P. H. Drenth, Witt, Heiko, Scholz, Marku, Sahin tóth, Miklós, Gastroenterology & Hepatology

المصدر: Recercat. Dipósit de la Recerca de Catalunya
instname
Gut 67, 1855–186 (2018)
Gut, 67, 1855-1863
Gut, 67, 10, pp. 1855-1863
Gut, 67(10), 1855-1863. BMJ Publishing Group

مصطلحات موضوعية: 0301 basic medicine, Linkage disequilibrium, medicine.medical_specialty, Settore MED/12 - GASTROENTEROLOGIA, Population, Genome Wide Association Study, Chronic Pancreatitis, Genetic Rearrangement, Locus (genetics), Single-nucleotide polymorphism, Genome-wide association study, Biology, Gastroenterology, chronic pancreatitis, 03 medical and health sciences, All institutes and research themes of the Radboud University Medical Center, Internal medicine, Genetic predisposition, medicine, Allele, education, Genetics, education.field_of_study, medicine.disease, ddc, genetic rearrangement, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], 030104 developmental biology, Genome wide association study, Pancreatitis, chronic pancreatiti, Chronic pancreatitis, Genetic rearrangement

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f321354751fbf2627fa55216c2c72c6
https://publica.fraunhofer.de/handle/publica/254910

المؤلفون: Miklós Sahin-Tóth

المصدر: Current Opinion in Gastroenterology

مصطلحات موضوعية: 0301 basic medicine, Protein Folding, enzyme misfolding, Carboxypeptidases A, Trypsinogen, chronic pancreatitis, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pancreatitis, Chronic, Medicine, Humans, Genetic Predisposition to Disease, Trypsin, Carboxypeptidase A1, Pathological, chemistry.chemical_classification, biology, hereditary pancreatitis, business.industry, Mechanism (biology), Endoplasmic reticulum, Gastroenterology, medicine.disease, Endoplasmic Reticulum Stress, 3. Good health, Enzyme Activation, 030104 developmental biology, Enzyme, chemistry, PANCREAS: Edited by Rodger Liddle, Immunology, Digestive enzyme, biology.protein, Pancreatitis, 030211 gastroenterology & hepatology, business, genetic susceptibility

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e1222f72f16a9d81c2d83dbb993a58a
https://pubmed.ncbi.nlm.nih.gov/28650851

المؤلفون: András Szabó, Miklós Sahin-Tóth, Anna Zsófia Tóth, Péter Hegyi, Eszter Hegyi

مصطلحات موضوعية: 0301 basic medicine, Gene isoform, Pathology, medicine.medical_specialty, Physiology, Enzyme-Linked Immunosorbent Assay, Biology, Transfection, 03 medical and health sciences, Feces, Predictive Value of Tests, Physiology (medical), medicine, Humans, Elméleti orvostudományok, Hepatology, medicine.diagnostic_test, Pancreatic Elastase, Stool test, Elastase, Gastroenterology, Genetic Variation, Reproducibility of Results, Orvostudományok, Clinical Enzyme Tests, Isoenzymes, 030104 developmental biology, medicine.anatomical_structure, HEK293 Cells, Molecular targets, Pancreatic Elastase 1, Reagent Kits, Diagnostic, Pancreas, Function (biology), Research Article

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc8fe9bc6a09c21f8873638ef82abd1
https://europepmc.org/articles/PMC5495912/